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Articles

Mechanisms of impairment of interferon production by SARS-CoV-2

In Collection

Coronavirus

Huy-Dung Hoang, Parisa Naeli, Tommy Alain, Seyed Mehdi Jafarnejad

Biochem Soc Trans (2023) BST20221037.

DOI: https://doi.org/10.1042/BST20221037

Published: 18 May 2023

View article titled, Mechanisms of impairment of interferon production by SARS-CoV-2

Articles

The CD56 − CD16 + NK cell subset in chronic infections

Alexander T.H. Cocker, Lisbeth A. Guethlein, Peter Parham

Biochem Soc Trans (2023) BST20221374.

DOI: https://doi.org/10.1042/BST20221374

Published: 04 May 2023

View article titled, The CD56 − CD16 + NK cell subset in chronic infections

Articles

Mitochondrial DNA as inflammatory DAMP: a warning of an aging immune system?

Giada Zanini, Valentina Selleri, Sandra Lopez Domenech, Mara Malerba, Milena Nasi, Anna Vittoria Mattioli, Marcello Pinti

Biochem Soc Trans (2023) 51 (2): 735–745.

DOI: https://doi.org/10.1042/BST20221010

Published: 04 April 2023

View article titled, Mitochondrial DNA as inflammatory DAMP: a warning of an aging immune system?

Articles

The interplay between monocytes, α-synuclein and LRRK2 in Parkinson's disease

Samuel Strader, Andrew B. West

Biochem Soc Trans (2023) 51 (2): 747–758.

DOI: https://doi.org/10.1042/BST20201091

Published: 04 April 2023

View article titled, The interplay between monocytes, α-synuclein and LRRK2 in Parkinson's disease

Articles

Immunosuppressive mechanisms of oncofetal reprogramming in the tumor microenvironment: implications in immunotherapy response

Jennifer Currenti, Archita Mishra, Michael Wallace, Jacob George, Ankur Sharma

Biochem Soc Trans (2023) 51 (2): 597–612.

DOI: https://doi.org/10.1042/BST20220157

Published: 20 March 2023

View article titled, Immunosuppressive mechanisms of oncofetal reprogramming in the tumor microenvironment: implications in immunotherapy response

Articles

The role of the blood–brain barrier during neurological disease and infection

Adjanie Patabendige, Damir Janigro

Biochem Soc Trans (2023) 51 (2): 613–626.

DOI: https://doi.org/10.1042/BST20220830

Published: 17 March 2023

View article titled, The role of the blood–brain barrier during neurological disease and infection

Articles

Mitochondrial dynamics in macrophages: divide to conquer or unite to survive?

Syeda Farhana Afroz, Karoline D. Raven, Grace M.E.P. Lawrence, Ronan Kapetanovic, Kate Schroder, Matthew J. Sweet

Biochem Soc Trans (2023) 51 (1): 41–56.

DOI: https://doi.org/10.1042/BST20220014

Published: 23 February 2023

View article titled, Mitochondrial dynamics in macrophages: divide to conquer or unite to survive?

Articles

Towards using 3D cellular cultures to model the activation and diverse functions of macrophages

Sean Cutter, Mark D. Wright, Nicholas P. Reynolds, Katrina Jean Binger

Biochem Soc Trans (2023) 51 (1): 387–401.

DOI: https://doi.org/10.1042/BST20221008

Published: 06 February 2023

View article titled, Towards using 3D cellular cultures to model the activation and diverse functions of macrophages

Articles

The mechanisms of alkali therapy in targeting renal diseases

Pedro Henrique Imenez Silva, Donald E. Wesson, Carsten A. Wagner

Biochem Soc Trans (2023) 51 (1): 223–232.

DOI: https://doi.org/10.1042/BST20220690

Published: 06 February 2023

View article titled, The mechanisms of alkali therapy in targeting renal diseases

Articles

Inflammatory cell death: how macrophages sense neighbouring cell infection and damage

Xiaohui Wang, Larisa I. Labzin

Biochem Soc Trans (2023) 51 (1): 303–313.

DOI: https://doi.org/10.1042/BST20220807

Published: 25 January 2023

View article titled, Inflammatory cell death: how macrophages sense neighbouring cell infection and damage

Articles

Advancing our knowledge of antigen processing with computational modelling, structural biology, and immunology

Steven Turner, Jonathan W. Essex, Tim Elliott

Biochem Soc Trans (2023) 51 (1): 275–285.

DOI: https://doi.org/10.1042/BST20220782

Published: 16 January 2023

View article titled, Advancing our knowledge of antigen processing with computational modelling, structural biology, and immunology

Articles

RNA interference, an emerging component of antiviral immunity in mammals

Dario Pasquale Anobile, Enzo Z. Poirier

Biochem Soc Trans (2023) 51 (1): 137–146.

DOI: https://doi.org/10.1042/BST20220385

Published: 06 January 2023

View article titled, RNA interference, an emerging component of antiviral immunity in mammals

Articles

Placental extracellular vesicles in maternal-fetal communication during pregnancy

Charlène Martin, Mathilde Bergamelli, Cécile E. Malnou, Gisela D'Angelo

Biochem Soc Trans (2022) 50 (6): 1785–1795.

DOI: https://doi.org/10.1042/BST20220734

Published: 09 December 2022

View article titled, Placental extracellular vesicles in maternal-fetal communication during pregnancy

Articles

The octadecanoids: an emerging class of lipid mediators

Alessandro Quaranta, Johanna Revol-Cavalier, Craig E. Wheelock

Biochem Soc Trans (2022) 50 (6): 1569–1582.

DOI: https://doi.org/10.1042/BST20210644

Published: 01 December 2022

View article titled, The octadecanoids: an emerging class of lipid mediators

Articles

Humoral immunity and B-cell memory in response to SARS-CoV-2 infection and vaccination

In Collection

Coronavirus

Holly A. Fryer, Gemma E. Hartley, Emily S.J. Edwards, Robyn E. O'Hehir, Menno C. van Zelm

Biochem Soc Trans (2022) 50 (6): 1643–1658.

DOI: https://doi.org/10.1042/BST20220415

Published: 24 November 2022

View article titled, Humoral immunity and B-cell memory in response to SARS-CoV-2 infection and vaccination

Articles

RIPK1 and RIPK3 in antibacterial defence

In Collection

Cell death and survival

Hui Wen Yeap, Kaiwen W. Chen

Biochem Soc Trans (2022) 50 (6): 1583–1594.

DOI: https://doi.org/10.1042/BST20211242

Published: 24 November 2022

View article titled, RIPK1 and RIPK3 in antibacterial defence

Articles

The intracellular signaling pathways governing macrophage activation and function in human atherosclerosis

Heather M. Wilson

Biochem Soc Trans (2022) 50 (6): 1673–1682.

DOI: https://doi.org/10.1042/BST20220441

Published: 23 November 2022

View article titled, The intracellular signaling pathways governing macrophage activation and function in human atherosclerosis

Articles

ISG15 driven cellular responses to virus infection

Deeksha Munnur, Adrianna Banducci-Karp, Sumana Sanyal

Biochem Soc Trans (2022) 50 (6): 1837–1846.

DOI: https://doi.org/10.1042/BST20220839

Published: 23 November 2022

View article titled, ISG15 driven cellular responses to virus infection

Articles

ERK1/2 in immune signalling

Richard M. Lucas, Lin Luo, Jennifer L. Stow

Biochem Soc Trans (2022) 50 (5): 1341–1352.

DOI: https://doi.org/10.1042/BST20220271

Published: 25 October 2022

View article titled, ERK1/2 in immune signalling

Articles

Dynamics of phagocytosis mediated by phosphatidylserine

Daan Vorselen

Biochem Soc Trans (2022) 50 (5): 1281–1291.

DOI: https://doi.org/10.1042/BST20211254

Published: 25 October 2022

View article titled, Dynamics of phagocytosis mediated by phosphatidylserine

Articles

Protective HLA-B57: T cell and natural killer cell recognition in HIV infection

Christian A. Lobos, Jonathan Downing, Lloyd J. D'Orsogna, Demetra S.M. Chatzileontiadou, Stephanie Gras

Biochem Soc Trans (2022) 50 (5): 1329–1339.

DOI: https://doi.org/10.1042/BST20220244

Published: 16 September 2022

View article titled, Protective HLA-B57: T cell and natural killer cell recognition in HIV infection

Articles

The role of RHIM in necroptosis

In Collection

Cell death and survival

Theresa Riebeling, Ulrich Kunzendorf, Stefan Krautwald

Biochem Soc Trans (2022) 50 (4): 1197–1205.

DOI: https://doi.org/10.1042/BST20220535

Published: 30 August 2022

View article titled, The role of RHIM in necroptosis

Articles

Host gene effects on gut microbiota in type 1 diabetes

Keyu Guo, Juan Huang, Zhiguang Zhou

Biochem Soc Trans (2022) 50 (3): 1133–1142.

DOI: https://doi.org/10.1042/BST20220004

Published: 06 May 2022

View article titled, Host gene effects on gut microbiota in type 1 diabetes

Articles

Transgenic mouse models to study the physiological and pathophysiological roles of human Siglecs

Kelli A. McCord, Matthew S. Macauley

Biochem Soc Trans (2022) 50 (2): 935–950.

DOI: https://doi.org/10.1042/BST20211203

Published: 06 April 2022

View article titled, Transgenic mouse models to study the physiological and pathophysiological roles of human Siglecs

Articles

Understanding immune signaling using advanced imaging techniques

Mario Brameshuber, Enrico Klotzsch, Aleks Ponjavic, Erdinc Sezgin

Biochem Soc Trans (2022) 50 (2): 853–866.

DOI: https://doi.org/10.1042/BST20210479

Published: 28 March 2022

View article titled, Understanding immune signaling using advanced imaging techniques

Articles

Regulation of the antigen presentation machinery in cancer and its implication for immune surveillance

Adithya Balasubramanian, Thomas John, Marie-Liesse Asselin-Labat

Biochem Soc Trans (2022) 50 (2): 825–837.

DOI: https://doi.org/10.1042/BST20210961

Published: 28 March 2022

View article titled, Regulation of the antigen presentation machinery in cancer and its implication for immune surveillance

Articles

Linear ubiquitination in immune and neurodegenerative diseases, and beyond

In Collection

Cell death and survival

Fuminori Tokunaga, Fumiyo Ikeda

Biochem Soc Trans (2022) 50 (2): 799–811.

DOI: https://doi.org/10.1042/BST20211078

Published: 28 March 2022

View article titled, Linear ubiquitination in immune and neurodegenerative diseases, and beyond

Articles

New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease

In Collection

Awards

Valerie B. O'Donnell

Biochem Soc Trans (2022) 50 (1): 1–11.

DOI: https://doi.org/10.1042/BST20210579

Published: 28 February 2022

View article titled, New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease

Articles

Role of macrophage extracellular traps in innate immunity and inflammatory disease

In Collection

Cell death and survival

Kristian H. Rasmussen, Clare L. Hawkins

Biochem Soc Trans (2022) 50 (1): 21–32.

DOI: https://doi.org/10.1042/BST20210962

Published: 22 February 2022

View article titled, Role of macrophage extracellular traps in innate immunity and inflammatory disease

Articles

Rare catastrophes and evolutionary legacies: human germline gene variants in MLKL and the necroptosis signalling pathway

In Collection

Cell death and survival

Sarah E. Garnish, Joanne M. Hildebrand

Biochem Soc Trans (2022) 50 (1): 529–539.

DOI: https://doi.org/10.1042/BST20210517

Published: 15 February 2022

View article titled, Rare catastrophes and evolutionary legacies: human germline gene variants in MLKL and the necroptosis signalling pathway

Articles

A proteomic perspective on TNF-mediated signalling and cell death

In Collection

Cell death and survival

Maria C. Tanzer

Biochem Soc Trans (2022) 50 (1): 13–20.

DOI: https://doi.org/10.1042/BST20211114

Published: 15 February 2022

View article titled, A proteomic perspective on TNF-mediated signalling and cell death

Articles

The role of IL-36 subfamily in intestinal disease

Peng Xu, Haidi Guan, Weidong Xiao, Lihua Sun

Biochem Soc Trans (2022) 50 (1): 223–230.

DOI: https://doi.org/10.1042/BST20211264

Published: 15 February 2022

View article titled, The role of IL-36 subfamily in intestinal disease

Articles

The interplay of helminthic neuropeptides and proteases in parasite survival and host immunomodulation

Rimanpreet Kaur, Naina Arora, Meera G. Nair, Amit Prasad

Biochem Soc Trans (2022) 50 (1): 107–118.

DOI: https://doi.org/10.1042/BST20210405

Published: 25 January 2022

View article titled, The interplay of helminthic neuropeptides and proteases in parasite survival and host immunomodulation

Articles

Defensin–lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics

Matthew J. A. Hein, Marc Kvansakul, Fung T. Lay, Thanh Kha Phan, Mark D. Hulett

Biochem Soc Trans (2022) 50 (1): 423–437.

DOI: https://doi.org/10.1042/BST20200884

Published: 11 January 2022

View article titled, Defensin–lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics

Articles

Identifying new molecular players in extracellular proteostasis

Sandeep Satapathy, Mark R. Wilson

Biochem Soc Trans (2022) 50 (1): 321–334.

DOI: https://doi.org/10.1042/BST20210369

Published: 23 December 2021

View article titled, Identifying new molecular players in extracellular proteostasis

Articles

PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

In Collection

Cell death and survival

Chloe M. McKee, Fabian A. Fischer, Jelena S. Bezbradica, Rebecca C. Coll

Biochem Soc Trans (2021) 49 (6): 2495–2507.

DOI: https://doi.org/10.1042/BST20200987

Published: 02 December 2021

View article titled, PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

Articles

Inflammasome-independent functions of NAIPs and NLRs in the intestinal epithelium

Lisa Scarfe, Gillian M. Mackie, Kendle M. Maslowski

Biochem Soc Trans (2021) 49 (6): 2601–2610.

DOI: https://doi.org/10.1042/BST20210365

Published: 02 December 2021

View article titled, Inflammasome-independent functions of NAIPs and NLRs in the intestinal epithelium

Articles

The emergence of SARS-CoV-2 variants threatens to decrease the efficacy of neutralizing antibodies and vaccines

Kensaku Murano, Youjia Guo, Haruhiko Siomi

Biochem Soc Trans (2021) 49 (6): 2879–2890.

DOI: https://doi.org/10.1042/BST20210859

Published: 02 December 2021

View article titled, The emergence of SARS-CoV-2 variants threatens to decrease the efficacy of neutralizing antibodies and vaccines

Articles

Applications of Cryo-EM in small molecule and biologics drug design

Joshua A. Lees, Joao M. Dias, Seungil Han

Biochem Soc Trans (2021) 49 (6): 2627–2638.

DOI: https://doi.org/10.1042/BST20210444

Published: 23 November 2021

View article titled, Applications of Cryo-EM in small molecule and biologics drug design

Articles

Molecular and structural aspects of gasdermin family pores and insights into gasdermin-elicited programmed cell death

In Collection

Cell death and survival

Ayesha Zahid, Hazrat Ismail, Tengchuan Jin

Biochem Soc Trans (2021) 49 (6): 2697–2710.

DOI: https://doi.org/10.1042/BST20210672

Published: 23 November 2021

View article titled, Molecular and structural aspects of gasdermin family pores and insights into gasdermin-elicited programmed cell death

Articles

Non-canonical roles of autophagy proteins in endocytosis and exocytosis

In Collection

Cell death and survival

Christian Münz

Biochem Soc Trans (2021) 49 (6): 2841–2851.

DOI: https://doi.org/10.1042/BST20210811

Published: 16 November 2021

View article titled, Non-canonical roles of autophagy proteins in endocytosis and exocytosis

Articles

Itaconate as an inflammatory mediator and therapeutic target in cardiovascular medicine

Marina Diotallevi, Faseeha Ayaz, Thomas Nicol, Mark J. Crabtree

Biochem Soc Trans (2021) 49 (5): 2189–2198.

DOI: https://doi.org/10.1042/BST20210269

Published: 19 October 2021

View article titled, Itaconate as an inflammatory mediator and therapeutic target in cardiovascular medicine

Articles

Modeling of human T cell development in vitro as a read-out for hematopoietic stem cell multipotency

Steven Strubbe, Tom Taghon

Biochem Soc Trans (2021) 49 (5): 2113–2122.

DOI: https://doi.org/10.1042/BST20210144

Published: 13 October 2021

View article titled, Modeling of human T cell development in vitro as a read-out for hematopoietic stem cell multipotency

Articles

An integrated view of innate immune mechanisms in C. elegans

Benjamin W. Harding, Jonathan J. Ewbank

Biochem Soc Trans (2021) 49 (5): 2307–2317.

DOI: https://doi.org/10.1042/BST20210399

Published: 08 October 2021

View article titled, An integrated view of innate immune mechanisms in C. elegans

Articles

The pockets guide to HLA class I molecules

Andrea T. Nguyen, Christopher Szeto, Stephanie Gras

Biochem Soc Trans (2021) 49 (5): 2319–2331.

DOI: https://doi.org/10.1042/BST20210410

Published: 28 September 2021

View article titled, The pockets guide to HLA class I molecules

Articles

Type 2 immunity in intestinal homeostasis and inflammatory bowel disease

Xinxin Luo, Eduardo J. Villablanca

Biochem Soc Trans (2021) 49 (5): 2371–2380.

DOI: https://doi.org/10.1042/BST20210535

Published: 28 September 2021

View article titled, Type 2 immunity in intestinal homeostasis and inflammatory bowel disease

Articles

Our evolving understanding of the role of the γδ T cell receptor in γδ T cell mediated immunity

Benjamin S. Gully, Jamie Rossjohn, Martin S. Davey

Biochem Soc Trans (2021) 49 (5): 1985–1995.

DOI: https://doi.org/10.1042/BST20200890

Published: 13 September 2021

View article titled, Our evolving understanding of the role of the γδ T cell receptor in γδ T cell mediated immunity

Articles

Post-translational modifications and stabilization of microtubules regulate transport of viral factors during infections

Silvia Requena, Francisco Sánchez-Madrid, Noa B. Martín-Cófreces

Biochem Soc Trans (2021) 49 (4): 1735–1748.

DOI: https://doi.org/10.1042/BST20210017

Published: 26 August 2021

View article titled, Post-translational modifications and stabilization of microtubules regulate transport of viral factors during infections

Articles

Extracellular Hsp90 and protection of neuronal cells through Nrf2

Stuart K. Calderwood, Thiago J. Borges, Takanori Eguchi, Benjamin J. Lang, Ayesha Murshid, Yuka Okusha, Thomas L. Prince

Biochem Soc Trans (2021) 49 (5): 2299–2306.

DOI: https://doi.org/10.1042/BST20210370

Published: 20 August 2021

View article titled, Extracellular Hsp90 and protection of neuronal cells through Nrf2

Articles

Are cachexia-associated tumors transmitTERS of ER stress?

Ana Sayuri Yamagata, Paula Paccielli Freire

Biochem Soc Trans (2021) 49 (4): 1841–1853.

DOI: https://doi.org/10.1042/BST20210496

Published: 02 August 2021

View article titled, Are cachexia-associated tumors transmitTERS of ER stress?

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