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Articles

Host gene effects on gut microbiota in type 1 diabetes

Keyu Guo, Juan Huang, Zhiguang Zhou

Biochem Soc Trans (2022) BST20220004.

DOI: https://doi.org/10.1042/BST20220004

Published: 06 May 2022

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Transgenic mouse models to study the physiological and pathophysiological roles of human Siglecs

Kelli A. McCord, Matthew S. Macauley

Biochem Soc Trans (2022) 50 (2): 935–950.

DOI: https://doi.org/10.1042/BST20211203

Published: 06 April 2022

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Articles

Understanding immune signaling using advanced imaging techniques

Mario Brameshuber, Enrico Klotzsch, Aleks Ponjavic, Erdinc Sezgin

Biochem Soc Trans (2022) 50 (2): 853–866.

DOI: https://doi.org/10.1042/BST20210479

Published: 28 March 2022

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Articles

Regulation of the antigen presentation machinery in cancer and its implication for immune surveillance

Adithya Balasubramanian, Thomas John, Marie-Liesse Asselin-Labat

Biochem Soc Trans (2022) 50 (2): 825–837.

DOI: https://doi.org/10.1042/BST20210961

Published: 28 March 2022

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Articles

Linear ubiquitination in immune and neurodegenerative diseases, and beyond

Fuminori Tokunaga, Fumiyo Ikeda

Biochem Soc Trans (2022) 50 (2): 799–811.

DOI: https://doi.org/10.1042/BST20211078

Published: 28 March 2022

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New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease

Valerie B. O'Donnell

Biochem Soc Trans (2022) 50 (1): 1–11.

DOI: https://doi.org/10.1042/BST20210579

Published: 28 February 2022

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Articles

Role of macrophage extracellular traps in innate immunity and inflammatory disease

Kristian H. Rasmussen, Clare L. Hawkins

Biochem Soc Trans (2022) 50 (1): 21–32.

DOI: https://doi.org/10.1042/BST20210962

Published: 22 February 2022

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Articles

Rare catastrophes and evolutionary legacies: human germline gene variants in MLKL and the necroptosis signalling pathway

Sarah E. Garnish, Joanne M. Hildebrand

Biochem Soc Trans (2022) 50 (1): 529–539.

DOI: https://doi.org/10.1042/BST20210517

Published: 15 February 2022

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Articles

A proteomic perspective on TNF-mediated signalling and cell death

Maria C. Tanzer

Biochem Soc Trans (2022) 50 (1): 13–20.

DOI: https://doi.org/10.1042/BST20211114

Published: 15 February 2022

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Articles

The role of IL-36 subfamily in intestinal disease

Peng Xu, Haidi Guan, Weidong Xiao, Lihua Sun

Biochem Soc Trans (2022) 50 (1): 223–230.

DOI: https://doi.org/10.1042/BST20211264

Published: 15 February 2022

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Articles

The interplay of helminthic neuropeptides and proteases in parasite survival and host immunomodulation

Rimanpreet Kaur, Naina Arora, Meera G. Nair, Amit Prasad

Biochem Soc Trans (2022) 50 (1): 107–118.

DOI: https://doi.org/10.1042/BST20210405

Published: 25 January 2022

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Articles

Defensin–lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics

Matthew J. A. Hein, Marc Kvansakul, Fung T. Lay, Thanh Kha Phan, Mark D. Hulett

Biochem Soc Trans (2022) 50 (1): 423–437.

DOI: https://doi.org/10.1042/BST20200884

Published: 11 January 2022

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Articles

Identifying new molecular players in extracellular proteostasis

Sandeep Satapathy, Mark R. Wilson

Biochem Soc Trans (2022) 50 (1): 321–334.

DOI: https://doi.org/10.1042/BST20210369

Published: 23 December 2021

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Articles

Inflammasome-independent functions of NAIPs and NLRs in the intestinal epithelium

Lisa Scarfe, Gillian M. Mackie, Kendle M. Maslowski

Biochem Soc Trans (2021) 49 (6): 2601–2610.

DOI: https://doi.org/10.1042/BST20210365

Published: 02 December 2021

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The emergence of SARS-CoV-2 variants threatens to decrease the efficacy of neutralizing antibodies and vaccines

Kensaku Murano, Youjia Guo, Haruhiko Siomi

Biochem Soc Trans (2021) 49 (6): 2879–2890.

DOI: https://doi.org/10.1042/BST20210859

Published: 02 December 2021

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Articles

PHOrming the inflammasome: phosphorylation is a critical switch in inflammasome signalling

Chloe M. McKee, Fabian A. Fischer, Jelena S. Bezbradica, Rebecca C. Coll

Biochem Soc Trans (2021) 49 (6): 2495–2507.

DOI: https://doi.org/10.1042/BST20200987

Published: 02 December 2021

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Articles

Applications of Cryo-EM in small molecule and biologics drug design

Joshua A. Lees, Joao M. Dias, Seungil Han

Biochem Soc Trans (2021) 49 (6): 2627–2638.

DOI: https://doi.org/10.1042/BST20210444

Published: 23 November 2021

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Articles

Molecular and structural aspects of gasdermin family pores and insights into gasdermin-elicited programmed cell death

Ayesha Zahid, Hazrat Ismail, Tengchuan Jin

Biochem Soc Trans (2021) 49 (6): 2697–2710.

DOI: https://doi.org/10.1042/BST20210672

Published: 23 November 2021

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Articles

Non-canonical roles of autophagy proteins in endocytosis and exocytosis

Christian Münz

Biochem Soc Trans (2021) 49 (6): 2841–2851.

DOI: https://doi.org/10.1042/BST20210811

Published: 16 November 2021

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Articles

Itaconate as an inflammatory mediator and therapeutic target in cardiovascular medicine

Marina Diotallevi, Faseeha Ayaz, Thomas Nicol, Mark J. Crabtree

Biochem Soc Trans (2021) 49 (5): 2189–2198.

DOI: https://doi.org/10.1042/BST20210269

Published: 19 October 2021

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Articles

Modeling of human T cell development in vitro as a read-out for hematopoietic stem cell multipotency

Steven Strubbe, Tom Taghon

Biochem Soc Trans (2021) 49 (5): 2113–2122.

DOI: https://doi.org/10.1042/BST20210144

Published: 13 October 2021

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Articles

An integrated view of innate immune mechanisms in C. elegans

Benjamin W. Harding, Jonathan J. Ewbank

Biochem Soc Trans (2021) 49 (5): 2307–2317.

DOI: https://doi.org/10.1042/BST20210399

Published: 08 October 2021

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Articles

The pockets guide to HLA class I molecules

Andrea T. Nguyen, Christopher Szeto, Stephanie Gras

Biochem Soc Trans (2021) 49 (5): 2319–2331.

DOI: https://doi.org/10.1042/BST20210410

Published: 28 September 2021

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Articles

Type 2 immunity in intestinal homeostasis and inflammatory bowel disease

Xinxin Luo, Eduardo J. Villablanca

Biochem Soc Trans (2021) 49 (5): 2371–2380.

DOI: https://doi.org/10.1042/BST20210535

Published: 28 September 2021

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Articles

Our evolving understanding of the role of the γδ T cell receptor in γδ T cell mediated immunity

Benjamin S. Gully, Jamie Rossjohn, Martin S. Davey

Biochem Soc Trans (2021) 49 (5): 1985–1995.

DOI: https://doi.org/10.1042/BST20200890

Published: 13 September 2021

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Articles

Post-translational modifications and stabilization of microtubules regulate transport of viral factors during infections

Silvia Requena, Francisco Sánchez-Madrid, Noa B. Martín-Cófreces

Biochem Soc Trans (2021) 49 (4): 1735–1748.

DOI: https://doi.org/10.1042/BST20210017

Published: 26 August 2021

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Articles

Extracellular Hsp90 and protection of neuronal cells through Nrf2

Stuart K. Calderwood, Thiago J. Borges, Takanori Eguchi, Benjamin J. Lang, Ayesha Murshid, Yuka Okusha, Thomas L. Prince

Biochem Soc Trans (2021) 49 (5): 2299–2306.

DOI: https://doi.org/10.1042/BST20210370

Published: 20 August 2021

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Articles

Are cachexia-associated tumors transmitTERS of ER stress?

Ana Sayuri Yamagata, Paula Paccielli Freire

Biochem Soc Trans (2021) 49 (4): 1841–1853.

DOI: https://doi.org/10.1042/BST20210496

Published: 02 August 2021

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Articles

The Hitchhiker's guide to glycoproteomics

Tiago Oliveira, Morten Thaysen-Andersen, Nicolle H. Packer, Daniel Kolarich

Biochem Soc Trans (2021) 49 (4): 1643–1662.

DOI: https://doi.org/10.1042/BST20200879

Published: 20 July 2021

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Articles

Metabolic determinants of B-cell selection

Lai N. Chan, Eamon Aghania, Etienne Leveille, Markus Müschen

Biochem Soc Trans (2021) 49 (3): 1467–1478.

DOI: https://doi.org/10.1042/BST20201316

Published: 01 July 2021

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Articles

Latest update on chemokine receptors as therapeutic targets

Wing Yee Lai, Anja Mueller

Biochem Soc Trans (2021) 49 (3): 1385–1395.

DOI: https://doi.org/10.1042/BST20201114

Published: 01 June 2021

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Articles

Great balls of fire: activation and signalling of inflammatory caspases

Georgia Bateman, Benjamin Hill, Ryan Knight, Dave Boucher

Biochem Soc Trans (2021) 49 (3): 1311–1324.

DOI: https://doi.org/10.1042/BST20200986

Published: 01 June 2021

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Articles

Interferon-induced GTPases orchestrate host cell-autonomous defence against bacterial pathogens

Heike L. Rafeld, Waldemar Kolanus, Ian R. van Driel, Elizabeth L. Hartland

Biochem Soc Trans (2021) 49 (3): 1287–1297.

DOI: https://doi.org/10.1042/BST20200900

Published: 18 May 2021

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Articles

Leucine-rich repeat kinase 2-related functions in GLIA: an update of the last years

Alice Filippini, Massimo Gennarelli, Isabella Russo

Biochem Soc Trans (2021) 49 (3): 1375–1384.

DOI: https://doi.org/10.1042/BST20201092

Published: 07 May 2021

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Articles

Heterochromatin and Polycomb as regulators of haematopoiesis

Christine R. Keenan

Biochem Soc Trans (2021) 49 (2): 805–814.

DOI: https://doi.org/10.1042/BST20200737

Published: 30 April 2021

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Articles

The complex, bidirectional role of extracellular vesicles in infection

Joni Renee White, Priscila Dauros-Singorenko, Jiwon Hong, Frédérique Vanholsbeeck, Anthony Phillips, Simon Swift

Biochem Soc Trans (2021) 49 (2): 881–891.

DOI: https://doi.org/10.1042/BST20200788

Published: 16 April 2021

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Articles

Phagocytic clearance of apoptotic, necrotic, necroptotic and pyroptotic cells

Georgia K. Atkin-Smith

Biochem Soc Trans (2021) 49 (2): 793–804.

DOI: https://doi.org/10.1042/BST20200696

Published: 12 April 2021

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Articles

Unlocking immune-mediated disease mechanisms with transcriptomics

Emma de Jong, Anthony Bosco

Biochem Soc Trans (2021) 49 (2): 705–714.

DOI: https://doi.org/10.1042/BST20200652

Published: 12 April 2021

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Articles

Bioengineered in vitro models of leukocyte–vascular interactions

Jaehyun Lee, Cort B. Breuer, Esak Lee

Biochem Soc Trans (2021) 49 (2): 693–704.

DOI: https://doi.org/10.1042/BST20200620

Published: 12 April 2021

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Articles

The role of lactobacilli in inhibiting skin pathogens

Lize Delanghe, Irina Spacova, Joke Van Malderen, Eline Oerlemans, Ingmar Claes, Sarah Lebeer

Biochem Soc Trans (2021) 49 (2): 617–627.

DOI: https://doi.org/10.1042/BST20200329

Published: 11 March 2021

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Articles

Keratan sulfate-based glycomimetics using Langerin as a target for COPD: lessons from studies on Fut8 and core fucose

Yuki Ohkawa, Yoichiro Harada, Naoyuki Taniguchi

Biochem Soc Trans (2021) 49 (1): 441–453.

DOI: https://doi.org/10.1042/BST20200780

Published: 22 February 2021

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Articles

Pore-forming toxins in infection and immunity

Pratima Verma, Shraddha Gandhi, Kusum Lata, Kausik Chattopadhyay

Biochem Soc Trans (2021) 49 (1): 455–465.

DOI: https://doi.org/10.1042/BST20200836

Published: 25 January 2021

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Articles

Understanding the immune responses involved in mediating protection or immunopathology during leishmaniasis

Thalia Pacheco-Fernandez, Greta Volpedo, Chaitenya Verma, Abhay R. Satoskar

Biochem Soc Trans (2021) 49 (1): 297–311.

DOI: https://doi.org/10.1042/BST20200606

Published: 15 January 2021

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Articles

Hypoxia signalling in the regulation of innate immune training

Lauren Eades, Michael Drozd, Richard M. Cubbon

Biochem Soc Trans (2022) 50 (1): 413–422.

DOI: https://doi.org/10.1042/BST20210857

Published: 11 January 2021

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Articles

The emerging roles of semaphorin4D/CD100 in immunological diseases

Liu Wang, Xiangfen Li, Yao Song, Dongzhe Song, Dingming Huang

Biochem Soc Trans (2020) 48 (6): 2875–2890.

DOI: https://doi.org/10.1042/BST20200821

Published: 01 December 2020

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Articles

Caveolin-1, tetraspanin CD81 and flotillins in lymphocyte cell membrane organization, signaling and immunopathology

Anna-Maria Schaffer, Susana Minguet

Biochem Soc Trans (2020) 48 (6): 2387–2397.

DOI: https://doi.org/10.1042/BST20190387

Published: 26 November 2020

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The development of proteinase-activated receptor-2 modulators and the challenges involved

Kathryn A. McIntosh, Margaret R. Cunningham, Trevor Bushell, Robin Plevin

Biochem Soc Trans (2020) 48 (6): 2525–2537.

DOI: https://doi.org/10.1042/BST20200191

Published: 26 November 2020

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Serological antibody testing in the COVID-19 pandemic: their molecular basis and applications

Jiayue-Clara Jiang, Yan Zhang

Biochem Soc Trans (2020) 48 (6): 2851–2863.

DOI: https://doi.org/10.1042/BST20200744

Published: 10 November 2020

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Mitochondrial DNA in innate immune responses against infectious diseases

Palamou Das, Oishee Chakrabarti

Biochem Soc Trans (2020) 48 (6): 2823–2838.

DOI: https://doi.org/10.1042/BST20200687

Published: 06 November 2020

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Small molecule ERK5 kinase inhibitors paradoxically activate ERK5 signalling: be careful what you wish for…

Simon J. Cook, Julie A. Tucker, Pamela A. Lochhead

Biochem Soc Trans (2020) 48 (5): 1859–1875.

DOI: https://doi.org/10.1042/BST20190338

Published: 11 September 2020

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