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Articles

NLR immune receptors: structure and function in plant disease resistance

Alexander Förderer, Jiorgos Kourelis
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1473–1483.
https://doi.org/10.1042/BST20221087
Published: 21 August 2023
View article titled, NLR immune receptors: structure and function in plant disease resistance
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Articles

Guanylate-binding proteins in virus infection

Simran Chhabra, Manjula Kalia
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1621–1633.
https://doi.org/10.1042/BST20221500
Published: 03 August 2023
View article titled, Guanylate-binding proteins in virus infection
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Articles

Mapping lipid pathways during phagocytosis

Ojal Saharan, Siddhesh S. Kamat
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1279–1287.
https://doi.org/10.1042/BST20221424
Published: 14 June 2023
View article titled, Mapping lipid pathways during phagocytosis
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Articles

Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence

In Collection
Coronavirus
Xiyuan Bai, Tony Schountz, Ashley M. Buckle, Janet L. Talbert, Robert A. Sandhaus, Edward D. Chan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1361–1375.
https://doi.org/10.1042/BST20230078
Published: 09 June 2023
View article titled, Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence
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Articles

Mechanisms of impairment of interferon production by SARS-CoV-2

In Collection
Coronavirus
Huy-Dung Hoang, Parisa Naeli, Tommy Alain, Seyed Mehdi Jafarnejad
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1047–1056.
https://doi.org/10.1042/BST20221037
Published: 18 May 2023
View article titled, Mechanisms of impairment of interferon production by SARS-CoV-2
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Articles

Recent insights into mechanisms of cellular toxicity and cell recognition associated with the ABC family of pore-forming toxins

Nadezhda A. Aleksandrova, Solace G. Roche, Yu Shang Low, Michael J. Landsberg
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1235–1244.
https://doi.org/10.1042/BST20221409
Published: 18 May 2023
View article titled, Recent insights into mechanisms of cellular toxicity and cell recognition associated with the ABC family of pore-forming toxins
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Articles

The role of Klebsiella populations in preterm infants

Anne L. McCartney, Lesley Hoyles
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 887–896.
https://doi.org/10.1042/BST20200325
Published: 26 April 2023
View article titled, The role of Klebsiella populations in preterm infants
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Includes: Supplementary data
Articles

The dynamic balance of the skin microbiome across the lifespan

Elizabeth C. Townsend, Lindsay R. Kalan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 71–86.
https://doi.org/10.1042/BST20220216
Published: 06 January 2023
View article titled, The dynamic balance of the skin microbiome across the lifespan
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Articles

RNA interference, an emerging component of antiviral immunity in mammals

Dario Pasquale Anobile, Enzo Z. Poirier
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 137–146.
https://doi.org/10.1042/BST20220385
Published: 06 January 2023
View article titled, RNA interference, an emerging component of antiviral immunity in mammals
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Articles

How viral infections cause neuronal dysfunction: a focus on the role of microglia and astrocytes

Shirin Hosseini, Martin Korte
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 259–274.
https://doi.org/10.1042/BST20220771
Published: 06 January 2023
View article titled, How viral infections cause neuronal dysfunction: a focus on the role of microglia and astrocytes
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Articles

RIPK1 and RIPK3 in antibacterial defence

In Collection
Cell death and survival
Hui Wen Yeap, Kaiwen W. Chen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1583–1594.
https://doi.org/10.1042/BST20211242
Published: 24 November 2022
View article titled, RIPK1 and RIPK3 in antibacterial defence
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Articles

ISG15 driven cellular responses to virus infection

Deeksha Munnur, Adrianna Banducci-Karp, Sumana Sanyal
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1837–1846.
https://doi.org/10.1042/BST20220839
Published: 23 November 2022
View article titled, ISG15 driven cellular responses to virus infection
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Articles

The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI

Dmitry Lyumkis, Nancy C. Horton
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1703–1714.
https://doi.org/10.1042/BST20220547
Published: 18 November 2022
View article titled, The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI
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Articles

The diverse arsenal of type III CRISPR–Cas-associated CARF and SAVED effectors

Jurre A. Steens, Carl Raymund P. Salazar, Raymond H.J. Staals
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1353–1364.
https://doi.org/10.1042/BST20220289
Published: 25 October 2022
View article titled, The diverse arsenal of type III CRISPR–Cas-associated CARF and SAVED effectors
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Articles

Relationship between mucosa-associated gut microbiota and human diseases

Nathalie Juge
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1225–1236.
https://doi.org/10.1042/BST20201201
Published: 10 October 2022
View article titled, Relationship between mucosa-associated gut microbiota and human diseases
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Articles

The long and the short of Periscope Proteins

Fiona Whelan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1293–1302.
https://doi.org/10.1042/BST20220194
Published: 05 October 2022
View article titled, The long and the short of Periscope Proteins
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Articles

Using genomics to understand the mechanisms of virulence and drug resistance in fungal pathogens

Miquel Àngel Schikora-Tamarit, Toni Gabaldón
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1259–1268.
https://doi.org/10.1042/BST20211123
Published: 17 June 2022
View article titled, Using genomics to understand the mechanisms of virulence and drug resistance in fungal pathogens
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Articles

CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact

Takahiro Ishizaki, Sophia Hernandez, Martina S. Paoletta, Theo Sanderson, Ellen S.C. Bushell
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1069–1079.
https://doi.org/10.1042/BST20210281
Published: 27 May 2022
View article titled, CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact
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Articles

Host gene effects on gut microbiota in type 1 diabetes

Keyu Guo, Juan Huang, Zhiguang Zhou
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1133–1142.
https://doi.org/10.1042/BST20220004
Published: 06 May 2022
View article titled, Host gene effects on gut microbiota in type 1 diabetes
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Articles

Organismal and cellular interactions in vertebrate–alga symbioses

Hui Yang, Baptiste Genot, Solange Duhamel, Ryan Kerney, John A. Burns
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 609–620.
https://doi.org/10.1042/BST20210153
Published: 28 February 2022
View article titled, Organismal and cellular interactions in vertebrate–alga symbioses
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Includes: Supplementary data
Articles

Understanding the key functions of Myosins in viral infection

Jiayi He, Yixing Qiu, Lei Tan, Deyong Duan, Xiaomin Yuan, Lingchen Yang, Aibing Wang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 597–607.
https://doi.org/10.1042/BST20211239
Published: 25 February 2022
View article titled, Understanding the key functions of Myosins in viral infection
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Articles

Three-dimensional insights into human enveloped viruses in vitro and in situ

Naveen Vankadari, Doulin C. Shepherd, Stephen D. Carter, Debnath Ghosal
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 95–105.
https://doi.org/10.1042/BST20210433
Published: 25 January 2022
View article titled, Three-dimensional insights into human enveloped viruses in vitro and in situ
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Articles

Defensin–lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics

Matthew J. A. Hein, Marc Kvansakul, Fung T. Lay, Thanh Kha Phan, Mark D. Hulett
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 423–437.
https://doi.org/10.1042/BST20200884
Published: 11 January 2022
View article titled, Defensin–lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics
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Articles

Inflammasome-independent functions of NAIPs and NLRs in the intestinal epithelium

Lisa Scarfe, Gillian M. Mackie, Kendle M. Maslowski
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2601–2610.
https://doi.org/10.1042/BST20210365
Published: 02 December 2021
View article titled, Inflammasome-independent functions of NAIPs and NLRs in the intestinal epithelium
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Articles

To export, or not to export: how nuclear export factor variants resolve Piwi's dilemma

Sheng Wang, Xiaohua Lu, Ding Qiu, Yang Yu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2073–2079.
https://doi.org/10.1042/BST20201171
Published: 13 October 2021
View article titled, To export, or not to export: how nuclear export factor variants resolve Piwi's dilemma
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Articles

An integrated view of innate immune mechanisms in C. elegans

Benjamin W. Harding, Jonathan J. Ewbank
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2307–2317.
https://doi.org/10.1042/BST20210399
Published: 08 October 2021
View article titled, An integrated view of innate immune mechanisms in C. elegans
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Articles

How activated NLRs induce anti-microbial defenses in plants

Farid El Kasmi
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2177–2188.
https://doi.org/10.1042/BST20210242
Published: 08 October 2021
View article titled, How activated NLRs induce anti-microbial defenses in plants
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Articles

Type 2 immunity in intestinal homeostasis and inflammatory bowel disease

Xinxin Luo, Eduardo J. Villablanca
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2371–2380.
https://doi.org/10.1042/BST20210535
Published: 28 September 2021
View article titled, Type 2 immunity in intestinal homeostasis and inflammatory bowel disease
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Articles

Post-translational modifications and stabilization of microtubules regulate transport of viral factors during infections

Silvia Requena, Francisco Sánchez-Madrid, Noa B. Martín-Cófreces
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1735–1748.
https://doi.org/10.1042/BST20210017
Published: 26 August 2021
View article titled, Post-translational modifications and stabilization of microtubules regulate transport of viral factors during infections
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Articles

Lipid–protein interactions in virus assembly and budding from the host cell plasma membrane

Balindile B. Motsa, Robert V. Stahelin
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1633–1641.
https://doi.org/10.1042/BST20200854
Published: 25 August 2021
View article titled, Lipid–protein interactions in virus assembly and budding from the host cell plasma membrane
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Articles

Integrated mass spectrometry-based multi-omics for elucidating mechanisms of bacterial virulence

Lok Man, William P. Klare, Ashleigh L. Dale, Joel A. Cain, Stuart J. Cordwell
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 1905–1926.
https://doi.org/10.1042/BST20191088
Published: 10 August 2021
View article titled, Integrated mass spectrometry-based multi-omics for elucidating mechanisms of bacterial virulence
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Articles

Host ADP-ribosylation and the SARS-CoV-2 macrodomain

Nicolas C. Hoch
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1711–1721.
https://doi.org/10.1042/BST20201212
Published: 05 August 2021
View article titled, Host ADP-ribosylation and the SARS-CoV-2 macrodomain
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Articles

Interferon-induced GTPases orchestrate host cell-autonomous defence against bacterial pathogens

Heike L. Rafeld, Waldemar Kolanus, Ian R. van Driel, Elizabeth L. Hartland
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (3): 1287–1297.
https://doi.org/10.1042/BST20200900
Published: 18 May 2021
View article titled, Interferon-induced GTPases orchestrate host cell-autonomous defence against bacterial pathogens
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Articles

The complex, bidirectional role of extracellular vesicles in infection

Joni Renee White, Priscila Dauros-Singorenko, Jiwon Hong, Frédérique Vanholsbeeck, Anthony Phillips, Simon Swift
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 881–891.
https://doi.org/10.1042/BST20200788
Published: 16 April 2021
View article titled, The complex, bidirectional role of extracellular vesicles in infection
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Articles

The role of lactobacilli in inhibiting skin pathogens

Lize Delanghe, Irina Spacova, Joke Van Malderen, Eline Oerlemans, Ingmar Claes, Sarah Lebeer
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 617–627.
https://doi.org/10.1042/BST20200329
Published: 11 March 2021
View article titled, The role of lactobacilli in inhibiting skin pathogens
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Articles

Rhizobia: highways to NO

Bryan Ruiz, Åsa Frostegård, Claude Bruand, Eliane Meilhoc
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 495–505.
https://doi.org/10.1042/BST20200989
Published: 05 February 2021
View article titled, Rhizobia: highways to NO
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Articles

Advances in modelling the human microbiome–gut–brain axis in vitro

Chrysanthi-Maria Moysidou, Róisín M. Owens
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 187–201.
https://doi.org/10.1042/BST20200338
Published: 05 February 2021
View article titled, Advances in modelling the human microbiome–gut–brain axis in vitro
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Articles

Pore-forming toxins in infection and immunity

Pratima Verma, Shraddha Gandhi, Kusum Lata, Kausik Chattopadhyay
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 455–465.
https://doi.org/10.1042/BST20200836
Published: 25 January 2021
View article titled, Pore-forming toxins in infection and immunity
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Articles

Understanding the immune responses involved in mediating protection or immunopathology during leishmaniasis

Thalia Pacheco-Fernandez, Greta Volpedo, Chaitenya Verma, Abhay R. Satoskar
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 297–311.
https://doi.org/10.1042/BST20200606
Published: 15 January 2021
View article titled, Understanding the immune responses involved in mediating protection or immunopathology during leishmaniasis
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Articles

Antivirals that target the host IMPα/β1-virus interface

Alexander J. Martin, David A. Jans
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 281–295.
https://doi.org/10.1042/BST20200568
Published: 13 January 2021
View article titled, Antivirals that target the host IMPα/β1-virus interface
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Articles

Varicella-zoster virus: molecular controls of cell fusion-dependent pathogenesis

Stefan L. Oliver, Momei Zhou, Ann M. Arvin
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (6): 2415–2435.
https://doi.org/10.1042/BST20190511
Published: 01 December 2020
View article titled, Varicella-zoster virus: molecular controls of cell fusion-dependent pathogenesis
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Articles

ER functions are exploited by viruses to support distinct stages of their life cycle

Yu-Jie Chen, Parikshit Bagchi, Billy Tsai
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 2173–2184.
https://doi.org/10.1042/BST20200395
Published: 29 October 2020
View article titled, ER functions are exploited by viruses to support distinct stages of their life cycle
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Articles

Transmission and prevention of SARS-CoV-2

In Collection
Coronavirus
Zhongyi Wang, Yingying Fu, Zhendong Guo, Jiaming Li, Jingjing Li, Hongliang Cheng, Bing Lu, Qiang Sun
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 2307–2316.
https://doi.org/10.1042/BST20200693
Published: 21 October 2020
View article titled, Transmission and prevention of SARS-CoV-2
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Articles

A ‘tad’ of hope in the fight against airway disease

Eamon Dubaissi
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 2347–2357.
https://doi.org/10.1042/BST20200745
Published: 20 October 2020
View article titled, A ‘tad’ of hope in the fight against airway disease
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Articles

The tryptophan biosynthetic pathway is essential for Mycobacterium tuberculosis to cause disease

J. Shaun Lott
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 2029–2037.
https://doi.org/10.1042/BST20200194
Published: 11 September 2020
View article titled, The tryptophan biosynthetic pathway is essential for Mycobacterium tuberculosis to cause disease
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Articles

Unleashing the therapeutic potential of apoptotic bodies

Thanh Kha Phan, Dilara Ceyda Ozkocak, Ivan Ka Ho Poon
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 2079–2088.
https://doi.org/10.1042/BST20200225
Published: 01 September 2020
View article titled, Unleashing the therapeutic potential of apoptotic bodies
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Articles

Like mother, like microbe: human milk oligosaccharide mediated microbiome symbiosis

Schuyler A. Chambers, Steven D. Townsend
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 1139–1151.
https://doi.org/10.1042/BST20191144
Published: 29 June 2020
View article titled, Like mother, like microbe: human milk oligosaccharide mediated microbiome symbiosis
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Articles

α-glucosidase inhibitors as host-directed antiviral agents with potential for the treatment of COVID-19

In Collection
Coronavirus
Spencer J. Williams, Ethan D. Goddard-Borger
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 1287–1295.
https://doi.org/10.1042/BST20200505
Published: 08 June 2020
View article titled, α-glucosidase inhibitors as host-directed antiviral agents with potential for the treatment of COVID-19
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Articles

Gut microbiota and metabolites in the pathogenesis of endocrine disease

Aline C. Fenneman, Elena Rampanelli, Yue S. Yin, Jesse Ames, Martin J. Blaser, Eric Fliers, Max Nieuwdorp
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 915–931.
https://doi.org/10.1042/BST20190686
Published: 15 May 2020
View article titled, Gut microbiota and metabolites in the pathogenesis of endocrine disease
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Articles

Using automated reasoning to explore the metabolism of unconventional organisms: a first step to explore host–microbial interactions

Clémence Frioux, Simon M. Dittami, Anne Siegel
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (3): 901–913.
https://doi.org/10.1042/BST20190667
Published: 07 May 2020
View article titled, Using automated reasoning to explore the metabolism of unconventional organisms: a first step to explore host–microbial interactions
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