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Articles

Experimental systems for the analysis of mutational signatures: no ‘one-size-fits-all' solution

Dmitri Ivanov, Taejoo Hwang, Lukasz Karol Sitko, Semin Lee, Anton Gartner

Biochem Soc Trans (2023) BST20221482.

DOI: https://doi.org/10.1042/BST20221482

Published: 07 June 2023

View article titled, Experimental systems for the analysis of mutational signatures: no ‘one-size-fits-all' solution

Articles

The functional importance of bacterial oxidative phosphonate pathways

Katharina Pallitsch, David L. Zechel

Biochem Soc Trans (2023) 51 (2): 487–499.

DOI: https://doi.org/10.1042/BST20220479

Published: 09 March 2023

View article titled, The functional importance of bacterial oxidative phosphonate pathways

Articles

Uncovering novel regulators of memory using C. elegans genetic and genomic analysis

Katie L. Brandel-Ankrapp, Rachel N. Arey

Biochem Soc Trans (2023) 51 (1): 161–171.

DOI: https://doi.org/10.1042/BST20220455

Published: 06 February 2023

View article titled, Uncovering novel regulators of memory using C. elegans genetic and genomic analysis

Articles

Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery

Lionel Urán Landaburu, Mercedes Didier Garnham, Fernán Agüero

Biochem Soc Trans (2023) 51 (1): 195–206.

DOI: https://doi.org/10.1042/BST20220618

Published: 06 January 2023

View article titled, Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery

Articles

Form and function of archaeal genomes

Stephen D. Bell

Biochem Soc Trans (2022) 50 (6): 1931–1939.

DOI: https://doi.org/10.1042/BST20221396

Published: 13 December 2022

View article titled, Form and function of archaeal genomes

Articles

General strategies for using amino acid sequence data to guide biochemical investigation of protein function

Emily N. Kennedy, Clay A. Foster, Sarah A. Barr, Robert B. Bourret

Biochem Soc Trans (2022) 50 (6): 1847–1858.

DOI: https://doi.org/10.1042/BST20220849

Published: 23 November 2022

View article titled, General strategies for using amino acid sequence data to guide biochemical investigation of protein function

Articles

Using genomics to understand the mechanisms of virulence and drug resistance in fungal pathogens

Miquel Àngel Schikora-Tamarit, Toni Gabaldón

Biochem Soc Trans (2022) 50 (3): 1259–1268.

DOI: https://doi.org/10.1042/BST20211123

Published: 17 June 2022

View article titled, Using genomics to understand the mechanisms of virulence and drug resistance in fungal pathogens

Articles

Investigating chromatin accessibility during development and differentiation by ATAC-sequencing to guide the identification of cis -regulatory elements

Emily Louise Smith, Gi Fay Mok, Andrea Münsterberg

Biochem Soc Trans (2022) 50 (3): 1167–1177.

DOI: https://doi.org/10.1042/BST20210834

Published: 23 May 2022

View article titled, Investigating chromatin accessibility during development and differentiation by ATAC-sequencing to guide the identification of cis -regulatory elements

Articles

Role of SWI/SNF chromatin remodeling genes in lung cancer development

Beatriz Monterde, Ignacio Varela

Biochem Soc Trans (2022) 50 (3): 1143–1150.

DOI: https://doi.org/10.1042/BST20211084

Published: 19 May 2022

View article titled, Role of SWI/SNF chromatin remodeling genes in lung cancer development

Articles

Encyclopaedia of eukaryotic DNA methylation: from patterns to mechanisms and functions

Peter Sarkies

Biochem Soc Trans (2022) 50 (3): 1179–1190.

DOI: https://doi.org/10.1042/BST20210725

Published: 06 May 2022

View article titled, Encyclopaedia of eukaryotic DNA methylation: from patterns to mechanisms and functions

Articles

Phenomics approaches to understand genetic networks and gene function in yeast

Clarence Hue Lok Yeung, Nil Sahin, Brenda Andrews

Biochem Soc Trans (2022) 50 (2): 713–721.

DOI: https://doi.org/10.1042/BST20210285

Published: 14 March 2022

View article titled, Phenomics approaches to understand genetic networks and gene function in yeast

Articles

Decoding the sorghum methylome: understanding epigenetic contributions to agronomic traits

Ulduz Vafadarshamasbi, Emma Mace, David Jordan, Peter A. Crisp

Biochem Soc Trans (2022) 50 (1): 583–596.

DOI: https://doi.org/10.1042/BST20210908

Published: 25 February 2022

View article titled, Decoding the sorghum methylome: understanding epigenetic contributions to agronomic traits

Articles

Rare catastrophes and evolutionary legacies: human germline gene variants in MLKL and the necroptosis signalling pathway

In Collection

Cell death and survival

Sarah E. Garnish, Joanne M. Hildebrand

Biochem Soc Trans (2022) 50 (1): 529–539.

DOI: https://doi.org/10.1042/BST20210517

Published: 15 February 2022

View article titled, Rare catastrophes and evolutionary legacies: human germline gene variants in MLKL and the necroptosis signalling pathway

Articles

Whole-genome methods to define DNA and histone accessibility and long-range interactions in chromatin

Luke T. Marr, Prasoon Jaya, Laxmi N. Mishra, Jeffrey J. Hayes

Biochem Soc Trans (2022) 50 (1): 199–212.

DOI: https://doi.org/10.1042/BST20210959

Published: 15 February 2022

View article titled, Whole-genome methods to define DNA and histone accessibility and long-range interactions in chromatin

Articles

Control of non-productive RNA polymerase II transcription via its early termination in metazoans

Jérôme O. Rouvière, Søren Lykke-Andersen, Torben Heick Jensen

Biochem Soc Trans (2022) 50 (1): 283–295.

DOI: https://doi.org/10.1042/BST20201140

Published: 15 February 2022

View article titled, Control of non-productive RNA polymerase II transcription via its early termination in metazoans

Articles

The role of chromatin at transcription-replication conflicts as a genome safeguard

Aleix Bayona-Feliu, Andrés Aguilera

Biochem Soc Trans (2021) 49 (6): 2727–2736.

DOI: https://doi.org/10.1042/BST20210691

Published: 25 November 2021

View article titled, The role of chromatin at transcription-replication conflicts as a genome safeguard

Articles

Programmed DNA elimination: silencing genes and repetitive sequences in somatic cells

Maxim V. Zagoskin, Jianbin Wang

Biochem Soc Trans (2021) 49 (5): 1891–1903.

DOI: https://doi.org/10.1042/BST20190951

Published: 19 October 2021

View article titled, Programmed DNA elimination: silencing genes and repetitive sequences in somatic cells

Articles

Integration of functional genomics data to uncover cell type-specific pathways affected in Parkinson's disease

Viola Volpato

Biochem Soc Trans (2021) 49 (5): 2091–2100.

DOI: https://doi.org/10.1042/BST20210128

Published: 28 September 2021

View article titled, Integration of functional genomics data to uncover cell type-specific pathways affected in Parkinson's disease

Articles

Regulation of retrotransposition in Arabidopsis

Seung Cho Lee, Robert A. Martienssen

Biochem Soc Trans (2021) 49 (5): 2241–2251.

DOI: https://doi.org/10.1042/BST20210337

Published: 08 September 2021

View article titled, Regulation of retrotransposition in Arabidopsis

Articles

Quantitative neurogenetics: applications in understanding disease

Ali Afrasiabi, Jeremy T. Keane, Julian Ik-Tsen Heng, Elizabeth E. Palmer, Nigel H. Lovell, Hamid Alinejad-Rokny

Biochem Soc Trans (2021) 49 (4): 1621–1631.

DOI: https://doi.org/10.1042/BST20200732

Published: 20 July 2021

View article titled, Quantitative neurogenetics: applications in understanding disease

Articles

Sequence determinants, function, and evolution of CpG islands

Allegra Angeloni, Ozren Bogdanovic

Biochem Soc Trans (2021) 49 (3): 1109–1119.

DOI: https://doi.org/10.1042/BST20200695

Published: 22 June 2021

View article titled, Sequence determinants, function, and evolution of CpG islands

Articles

Molecular genetics of renal ciliopathies

Miguel Barroso-Gil, Eric Olinger, John A. Sayer

Biochem Soc Trans (2021) 49 (3): 1205–1220.

DOI: https://doi.org/10.1042/BST20200791

Published: 07 May 2021

View article titled, Molecular genetics of renal ciliopathies

Articles

Dynamics of bacterial adaptation

Huei-Yi Lai, Tim F. Cooper

Biochem Soc Trans (2021) 49 (2): 945–951.

DOI: https://doi.org/10.1042/BST20200885

Published: 12 April 2021

View article titled, Dynamics of bacterial adaptation

Articles

Beyond the pan-genome: current perspectives on the functional and practical outcomes of the distributed genome hypothesis

Jocelyn A. Hammond, Emma A. Gordon, Kayla M. Socarras, Joshua Chang Mell, Garth D. Ehrlich

Biochem Soc Trans (2020) 48 (6): 2437–2455.

DOI: https://doi.org/10.1042/BST20190713

Published: 27 November 2020

View article titled, Beyond the pan-genome: current perspectives on the functional and practical outcomes of the distributed genome hypothesis

Articles

Decoding co-/post-transcriptional complexities of plant transcriptomes and epitranscriptome using next-generation sequencing technologies

Anireddy S.N. Reddy, Jie Huang, Naeem H. Syed, Asa Ben-Hur, Suomeng Dong, Lianfeng Gu

Biochem Soc Trans (2020) 48 (6): 2399–2414.

DOI: https://doi.org/10.1042/BST20190492

Published: 16 November 2020

View article titled, Decoding co-/post-transcriptional complexities of plant transcriptomes and epitranscriptome using next-generation sequencing technologies

Includes: Supplementary data

Articles

Architectural RNA in chromatin organization

Jitendra Thakur, Steven Henikoff

Biochem Soc Trans (2020) 48 (5): 1967–1978.

DOI: https://doi.org/10.1042/BST20191226

Published: 08 September 2020

View article titled, Architectural RNA in chromatin organization

Articles

The evolutionary dynamics of venom toxins made by insects and other animals

Andrew A. Walker

Biochem Soc Trans (2020) 48 (4): 1353–1365.

DOI: https://doi.org/10.1042/BST20190820

Published: 05 August 2020

View article titled, The evolutionary dynamics of venom toxins made by insects and other animals

Articles

DNA copy number and structural variation (CNV) contributions to adult and childhood obesity

Megan Phillips, Jeganathan Ramesh Babu, Xu Wang, Thangiah Geetha

Biochem Soc Trans (2020) 48 (4): 1819–1828.

DOI: https://doi.org/10.1042/BST20200556

Published: 29 July 2020

View article titled, DNA copy number and structural variation (CNV) contributions to adult and childhood obesity

Articles

Computational discovery and modeling of novel gene expression rules encoded in the mRNA

Shir Bahiri-Elitzur, Tamir Tuller

Biochem Soc Trans (2020) 48 (4): 1519–1528.

DOI: https://doi.org/10.1042/BST20191048

Published: 14 July 2020

View article titled, Computational discovery and modeling of novel gene expression rules encoded in the mRNA

Articles

Small nucleolar RNAs: continuing identification of novel members and increasing diversity of their molecular mechanisms of action

Danny Bergeron, Étienne Fafard-Couture, Michelle S. Scott

Biochem Soc Trans (2020) 48 (2): 645–656.

DOI: https://doi.org/10.1042/BST20191046

Published: 08 April 2020

View article titled, Small nucleolar RNAs: continuing identification of novel members and increasing diversity of their molecular mechanisms of action

Articles

Detection of CRISPR adaptation

Anna Shiriaeva, Ivan Fedorov, Danylo Vyhovskyi, Konstantin Severinov

Biochem Soc Trans (2020) 48 (1): 257–269.

DOI: https://doi.org/10.1042/BST20190662

Published: 03 February 2020

View article titled, Detection of CRISPR adaptation

Includes: Supplementary data

Articles

Using single-cell RNA sequencing to unravel cell lineage relationships in the respiratory tract

L.E. Zaragosi, M. Deprez, P. Barbry

Biochem Soc Trans (2020) 48 (1): 327–336.

DOI: https://doi.org/10.1042/BST20191010

Published: 10 January 2020

View article titled, Using single-cell RNA sequencing to unravel cell lineage relationships in the respiratory tract

Articles

Characterization and applications of Type I CRISPR-Cas systems

Claudio Hidalgo-Cantabrana, Rodolphe Barrangou

Biochem Soc Trans (2020) 48 (1): 15–23.

DOI: https://doi.org/10.1042/BST20190119

Published: 10 January 2020

View article titled, Characterization and applications of Type I CRISPR-Cas systems

Articles

‘Stop’ in protein synthesis is modulated with exquisite subtlety by an extended RNA translation signal

Warren P. Tate, Andrew G. Cridge, Chris M. Brown

Biochem Soc Trans (2018) 46 (6): 1615–1625.

DOI: https://doi.org/10.1042/BST20180190

Published: 12 November 2018

View article titled, ‘Stop’ in protein synthesis is modulated with exquisite subtlety by an extended RNA translation signal

Articles

The molecular clock and evolutionary timescales

Arong Luo, Simon Y. W. Ho

Biochem Soc Trans (2018) 46 (5): 1183–1190.

DOI: https://doi.org/10.1042/BST20180186

Published: 28 August 2018

View article titled, The molecular clock and evolutionary timescales

Articles

The biological relevance of a medieval king's DNA

Maarten H.D. Larmuseau, Martin Bodner

Biochem Soc Trans (2018) 46 (4): 1013–1020.

DOI: https://doi.org/10.1042/BST20170173

Published: 31 July 2018

View article titled, The biological relevance of a medieval king's DNA

Articles

RHO GTPases in cancer: known facts, open questions, and therapeutic challenges

Xosé R. Bustelo

Biochem Soc Trans (2018) 46 (3): 741–760.

DOI: https://doi.org/10.1042/BST20170531

Published: 05 June 2018

View article titled, RHO GTPases in cancer: known facts, open questions, and therapeutic challenges

Articles

Studying X chromosome inactivation in the single-cell genomic era

Andrew Keniry, Marnie E. Blewitt

Biochem Soc Trans (2018) 46 (3): 577–586.

DOI: https://doi.org/10.1042/BST20170346

Published: 20 April 2018

View article titled, Studying X chromosome inactivation in the single-cell genomic era

Articles

Biomolecular coevolution and its applications: Going from structure prediction toward signaling, epistasis, and function

Mehari B. Zerihun, Alexander Schug

Biochem Soc Trans (2017) 45 (6): 1253–1261.

DOI: https://doi.org/10.1042/BST20170063

Published: 20 October 2017

View article titled, Biomolecular coevolution and its applications: Going from structure prediction toward signaling, epistasis, and function

Articles

When mRNA translation meets decay

Alicia A. Bicknell, Emiliano P. Ricci

Biochem Soc Trans (2017) 45 (2): 339–351.

DOI: https://doi.org/10.1042/BST20160243

Published: 13 April 2017

View article titled, When mRNA translation meets decay

Articles

Constraints in cancer evolution

Subramanian Venkatesan, Nicolai J. Birkbak, Charles Swanton

Biochem Soc Trans (2017) 45 (1): 1–13.

DOI: https://doi.org/10.1042/BST20160229

Published: 15 February 2017

View article titled, Constraints in cancer evolution

Articles

Structure and function of bacterial H-NS protein

David C. Grainger

Biochem Soc Trans (2016) 44 (6): 1561–1569.

DOI: https://doi.org/10.1042/BST20160190

Published: 02 December 2016

View article titled, Structure and function of bacterial H-NS protein

Articles

Dawn of the in vivo RNA structurome and interactome

Chun Kit Kwok

Biochem Soc Trans (2016) 44 (5): 1395–1410.

DOI: https://doi.org/10.1042/BST20160075

Published: 19 October 2016

View article titled, Dawn of the in vivo RNA structurome and interactome

Articles

‘Nothing of chemistry disappears in biology’: the Top 30 damage-prone endogenous metabolites

Claudia Lerma-Ortiz, James G. Jeffryes, Arthur J.L. Cooper, Thomas D. Niehaus, Antje M.K. Thamm, Océane Frelin, Thomas Aunins, Oliver Fiehn, Valérie de Crécy-Lagard, Christopher S. Henry, Andrew D. Hanson

Biochem Soc Trans (2016) 44 (3): 961–971.

DOI: https://doi.org/10.1042/BST20160073

Published: 09 June 2016

View article titled, ‘Nothing of chemistry disappears in biology’: the Top 30 damage-prone endogenous metabolites

Includes: Supplementary data

Articles

Mutational patterns in oncogenes and tumour suppressors

Hanadi M. Baeissa, Graeme Benstead-Hume, Christopher J. Richardson, Frances M.G. Pearl

Biochem Soc Trans (2016) 44 (3): 925–931.

DOI: https://doi.org/10.1042/BST20160001

Published: 09 June 2016

View article titled, Mutational patterns in oncogenes and tumour suppressors

Includes: Supplementary data

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