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Articles

Cytoophidia and filaments: you must unlearn what you have learned

Chen-Jun Guo, Ji-Long Liu

Biochem Soc Trans (2023) BST20221410.

DOI: https://doi.org/10.1042/BST20221410

Published: 30 May 2023

View article titled, Cytoophidia and filaments: you must unlearn what you have learned

Articles

The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation

Shang Liang, Rajaei Almohammed, Victoria H. Cowling

Biochem Soc Trans (2023) BST20221154.

DOI: https://doi.org/10.1042/BST20221154

Published: 05 May 2023

View article titled, The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation

Includes: Supplementary data

Articles

The molecular mechanisms of human separase regulation

Jun Yu, David O. Morgan, Andreas Boland

Biochem Soc Trans (2023) BST20221400.

DOI: https://doi.org/10.1042/BST20221400

Published: 04 May 2023

View article titled, The molecular mechanisms of human separase regulation

Articles

The functional importance of bacterial oxidative phosphonate pathways

Katharina Pallitsch, David L. Zechel

Biochem Soc Trans (2023) 51 (2): 487–499.

DOI: https://doi.org/10.1042/BST20220479

Published: 09 March 2023

View article titled, The functional importance of bacterial oxidative phosphonate pathways

Articles

Deciphering the mechanism and function of Hsp100 unfoldases from protein structure

Grace Lee, Rebecca S. Kim, Sang Bum Lee, Sukyeong Lee, Francis T.F. Tsai

Biochem Soc Trans (2022) 50 (6): 1725–1736.

DOI: https://doi.org/10.1042/BST20220590

Published: 01 December 2022

View article titled, Deciphering the mechanism and function of Hsp100 unfoldases from protein structure

Articles

General strategies for using amino acid sequence data to guide biochemical investigation of protein function

Emily N. Kennedy, Clay A. Foster, Sarah A. Barr, Robert B. Bourret

Biochem Soc Trans (2022) 50 (6): 1847–1858.

DOI: https://doi.org/10.1042/BST20220849

Published: 23 November 2022

View article titled, General strategies for using amino acid sequence data to guide biochemical investigation of protein function

Articles

The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI

Dmitry Lyumkis, Nancy C. Horton

Biochem Soc Trans (2022) 50 (6): 1703–1714.

DOI: https://doi.org/10.1042/BST20220547

Published: 18 November 2022

View article titled, The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI

Articles

The functional importance of VCP to maintaining cellular protein homeostasis

Brittany A. Ahlstedt, Rakesh Ganji, Malavika Raman

Biochem Soc Trans (2022) 50 (5): 1457–1469.

DOI: https://doi.org/10.1042/BST20220648

Published: 05 October 2022

View article titled, The functional importance of VCP to maintaining cellular protein homeostasis

Articles

Unveiling the mechanisms and biosynthesis of a novel nickel-pincer enzyme

Shramana Chatterjee, Santhosh Gatreddi, Swati Gupta, Jorge L. Nevarez, Joel A. Rankin, Aiko Turmo, Jian Hu, Robert P. Hausinger

Biochem Soc Trans (2022) 50 (4): 1187–1196.

DOI: https://doi.org/10.1042/BST20220490

Published: 12 August 2022

View article titled, Unveiling the mechanisms and biosynthesis of a novel nickel-pincer enzyme

Articles

New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease

In Collection

Awards

Valerie B. O'Donnell

Biochem Soc Trans (2022) 50 (1): 1–11.

DOI: https://doi.org/10.1042/BST20210579

Published: 28 February 2022

View article titled, New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease

Articles

IMPDH dysregulation in disease: a mini review

Anika L. Burrell, Justin M. Kollman

Biochem Soc Trans (2022) 50 (1): 71–82.

DOI: https://doi.org/10.1042/BST20210446

Published: 22 February 2022

View article titled, IMPDH dysregulation in disease: a mini review

Articles

The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation

Daria Sicari, Janine Weber, Elena Maspero, Simona Polo

Biochem Soc Trans (2022) 50 (1): 473–485.

DOI: https://doi.org/10.1042/BST20210731

Published: 07 February 2022

View article titled, The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation

Articles

Improving photosynthesis through the enhancement of Rubisco carboxylation capacity

Concepción Iñiguez, Pere Aguiló-Nicolau, Jeroni Galmés

Biochem Soc Trans (2021) 49 (5): 2007–2019.

DOI: https://doi.org/10.1042/BST20201056

Published: 08 October 2021

View article titled, Improving photosynthesis through the enhancement of Rubisco carboxylation capacity

Articles

The surprising structural and mechanistic dichotomy of membrane-associated phosphoglycosyl transferases

Katherine H. O'Toole, Hannah M. Bernstein, Karen N. Allen, Barbara Imperiali

Biochem Soc Trans (2021) 49 (3): 1189–1203.

DOI: https://doi.org/10.1042/BST20200762

Published: 08 June 2021

View article titled, The surprising structural and mechanistic dichotomy of membrane-associated phosphoglycosyl transferases

Articles

Great balls of fire: activation and signalling of inflammatory caspases

Georgia Bateman, Benjamin Hill, Ryan Knight, Dave Boucher

Biochem Soc Trans (2021) 49 (3): 1311–1324.

DOI: https://doi.org/10.1042/BST20200986

Published: 01 June 2021

View article titled, Great balls of fire: activation and signalling of inflammatory caspases

Articles

Serpins in cartilage and osteoarthritis: what do we know?

David J. Wilkinson

Biochem Soc Trans (2021) 49 (2): 1013–1026.

DOI: https://doi.org/10.1042/BST20201231

Published: 12 April 2021

View article titled, Serpins in cartilage and osteoarthritis: what do we know?

Articles

Collagen hydroxylysine glycosylation: non-conventional substrates for atypical glycosyltransferase enzymes

Francesca De Giorgi, Marco Fumagalli, Luigi Scietti, Federico Forneris

Biochem Soc Trans (2021) 49 (2): 855–866.

DOI: https://doi.org/10.1042/BST20200767

Published: 11 March 2021

View article titled, Collagen hydroxylysine glycosylation: non-conventional substrates for atypical glycosyltransferase enzymes

Articles

Plant asparaginyl endopeptidases and their structural determinants of function

Samuel G. Nonis, Joel Haywood, Joshua S. Mylne

Biochem Soc Trans (2021) 49 (2): 965–976.

DOI: https://doi.org/10.1042/BST20200908

Published: 05 March 2021

View article titled, Plant asparaginyl endopeptidases and their structural determinants of function

Articles

Structure and evolution of the bifidobacterial carbohydrate metabolism proteins and enzymes

Shinya Fushinobu, Maher Abou Hachem

Biochem Soc Trans (2021) 49 (2): 563–578.

DOI: https://doi.org/10.1042/BST20200163

Published: 05 March 2021

View article titled, Structure and evolution of the bifidobacterial carbohydrate metabolism proteins and enzymes

Articles

Computational investigations of allostery in aromatic amino acid biosynthetic enzymes

Wanting Jiao

Biochem Soc Trans (2021) 49 (1): 415–429.

DOI: https://doi.org/10.1042/BST20200741

Published: 05 February 2021

View article titled, Computational investigations of allostery in aromatic amino acid biosynthetic enzymes

Articles

Lytic polysaccharide monooxygenases and other histidine-brace copper proteins: structure, oxygen activation and biotechnological applications

Johan Ø. Ipsen, Magnus Hallas-Møller, Søren Brander, Leila Lo Leggio, Katja S. Johansen

Biochem Soc Trans (2021) 49 (1): 531–540.

DOI: https://doi.org/10.1042/BST20201031

Published: 15 January 2021

View article titled, Lytic polysaccharide monooxygenases and other histidine-brace copper proteins: structure, oxygen activation and biotechnological applications

Articles

Solid-state NMR approaches to investigate large enzymes in complex with substrates and inhibitors

Anne K. Schütz

Biochem Soc Trans (2021) 49 (1): 131–144.

DOI: https://doi.org/10.1042/BST20200099

Published: 24 December 2020

View article titled, Solid-state NMR approaches to investigate large enzymes in complex with substrates and inhibitors

Articles

Anatomy of a twin DNA replication factory

Huilin Li, Nina Y. Yao, Michael E. O'Donnell

Biochem Soc Trans (2020) 48 (6): 2769–2778.

DOI: https://doi.org/10.1042/BST20200640

Published: 10 December 2020

View article titled, Anatomy of a twin DNA replication factory

Articles

‘PIPs’ in DNA polymerase: PCNA interaction affairs

Narottam Acharya, Shraddheya Kumar Patel, Satya Ranjan Sahu, Premlata Kumari

Biochem Soc Trans (2020) 48 (6): 2811–2822.

DOI: https://doi.org/10.1042/BST20200678

Published: 16 November 2020

View article titled, ‘PIPs’ in DNA polymerase: PCNA interaction affairs

Articles

Protein phosphatase-1: dual activity regulation by Inhibitor-2

Sarah Lemaire, Mathieu Bollen

Biochem Soc Trans (2020) 48 (5): 2229–2240.

DOI: https://doi.org/10.1042/BST20200503

Published: 14 October 2020

View article titled, Protein phosphatase-1: dual activity regulation by Inhibitor-2

Articles

Biosynthesis of lanthionine-constrained agonists of G protein-coupled receptors

Gert N. Moll, Anneke Kuipers, Rick Rink, Tjibbe Bosma, Louwe de Vries, Pawel Namsolleck

Biochem Soc Trans (2020) 48 (5): 2195–2203.

DOI: https://doi.org/10.1042/BST20200427

Published: 14 October 2020

View article titled, Biosynthesis of lanthionine-constrained agonists of G protein-coupled receptors

Articles

Human 2-oxoglutarate-dependent oxygenases: nutrient sensors, stress responders, and disease mediators

Sally C. Fletcher, Mathew L. Coleman

Biochem Soc Trans (2020) 48 (5): 1843–1858.

DOI: https://doi.org/10.1042/BST20190333

Published: 28 September 2020

View article titled, Human 2-oxoglutarate-dependent oxygenases: nutrient sensors, stress responders, and disease mediators

Articles

The tryptophan biosynthetic pathway is essential for Mycobacterium tuberculosis to cause disease

J. Shaun Lott

Biochem Soc Trans (2020) 48 (5): 2029–2037.

DOI: https://doi.org/10.1042/BST20200194

Published: 11 September 2020

View article titled, The tryptophan biosynthetic pathway is essential for Mycobacterium tuberculosis to cause disease

Articles

Driving antimalarial design through understanding of target mechanism

Petar P. S. Calic, Mahta Mansouri, Peter J. Scammells, Sheena McGowan

Biochem Soc Trans (2020) 48 (5): 2067–2078.

DOI: https://doi.org/10.1042/BST20200224

Published: 01 September 2020

View article titled, Driving antimalarial design through understanding of target mechanism

Articles

Chain reactions: molecular mechanisms of RBR ubiquitin ligases

Thomas R. Cotton, Bernhard C. Lechtenberg

Biochem Soc Trans (2020) 48 (4): 1737–1750.

DOI: https://doi.org/10.1042/BST20200237

Published: 17 July 2020

View article titled, Chain reactions: molecular mechanisms of RBR ubiquitin ligases

Articles

Leloir glycosyltransferases of natural product C -glycosylation: structure, mechanism and specificity

Gregor Tegl, Bernd Nidetzky

Biochem Soc Trans (2020) 48 (4): 1583–1598.

DOI: https://doi.org/10.1042/BST20191140

Published: 13 July 2020

View article titled, Leloir glycosyltransferases of natural product C -glycosylation: structure, mechanism and specificity

Articles

Functional (un)cooperativity in elevator transport proteins

Katharina Holzhüter, Eric R. Geertsma

Biochem Soc Trans (2020) 48 (3): 1047–1055.

DOI: https://doi.org/10.1042/BST20190970

Published: 23 June 2020

View article titled, Functional (un)cooperativity in elevator transport proteins

Articles

Engineered peptide ligases for cell signaling and bioconjugation

Clara L. Frazier, Amy M. Weeks

Biochem Soc Trans (2020) 48 (3): 1153–1165.

DOI: https://doi.org/10.1042/BST20200001

Published: 15 June 2020

View article titled, Engineered peptide ligases for cell signaling and bioconjugation

Articles

Cytotoxicity of snake venom enzymatic toxins: phospholipase A2 and l-amino acid oxidase

Jia Jin Hiu, Michelle Khai Khun Yap

Biochem Soc Trans (2020) 48 (2): 719–731.

DOI: https://doi.org/10.1042/BST20200110

Published: 08 April 2020

View article titled, Cytotoxicity of snake venom enzymatic toxins: phospholipase A2 and l-amino acid oxidase

Articles

Signal-regulated oxidation of proteins via MICAL

Clara Ortegón Salas, Katharina Schneider, Christopher Horst Lillig, Manuela Gellert

Biochem Soc Trans (2020) 48 (2): 613–620.

DOI: https://doi.org/10.1042/BST20190866

Published: 27 March 2020

View article titled, Signal-regulated oxidation of proteins via MICAL

Articles

Small molecules that target the ubiquitin system

Hai Qiu Wu, David Baker, Huib Ovaa

Biochem Soc Trans (2020) 48 (2): 479–497.

DOI: https://doi.org/10.1042/BST20190535

Published: 20 March 2020

View article titled, Small molecules that target the ubiquitin system

Articles

Inorganic polyphosphate in mammals: where's Wally?

Yann Desfougères, Adolfo Saiardi, Cristina Azevedo

Biochem Soc Trans (2020) 48 (1): 95–101.

DOI: https://doi.org/10.1042/BST20190328

Published: 12 February 2020

View article titled, Inorganic polyphosphate in mammals: where's Wally?

Articles

Editor's cut: DNA cleavage by CRISPR RNA-guided nucleases Cas9 and Cas12a

Thomas Swartjes, Raymond H.J. Staals, John van der Oost

Biochem Soc Trans (2020) 48 (1): 207–219.

DOI: https://doi.org/10.1042/BST20190563

Published: 24 December 2019

View article titled, Editor's cut: DNA cleavage by CRISPR RNA-guided nucleases Cas9 and Cas12a

Articles

Bacterial DUBs: deubiquitination beyond the seven classes

Thomas Hermanns, Kay Hofmann

Biochem Soc Trans (2019) 47 (6): 1857–1866.

DOI: https://doi.org/10.1042/BST20190526

Published: 17 December 2019

View article titled, Bacterial DUBs: deubiquitination beyond the seven classes

Articles

Multitalented actors inside and outside the cell: recent discoveries add to the number of moonlighting proteins

Constance J. Jeffery

Biochem Soc Trans (2019) 47 (6): 1941–1948.

DOI: https://doi.org/10.1042/BST20190798

Published: 05 December 2019

View article titled, Multitalented actors inside and outside the cell: recent discoveries add to the number of moonlighting proteins

Articles

Beyond reversal: ubiquitin and ubiquitin-like proteases and the orchestration of the DNA double strand break repair response

Alexander J. Garvin

Biochem Soc Trans (2019) 47 (6): 1881–1893.

DOI: https://doi.org/10.1042/BST20190534

Published: 26 November 2019

View article titled, Beyond reversal: ubiquitin and ubiquitin-like proteases and the orchestration of the DNA double strand break repair response

Articles

How is the acyl chain composition of phosphoinositides created and does it matter?

David Barneda, Sabina Cosulich, Len Stephens, Phillip Hawkins

Biochem Soc Trans (2019) 47 (5): 1291–1305.

DOI: https://doi.org/10.1042/BST20190205

Published: 28 October 2019

View article titled, How is the acyl chain composition of phosphoinositides created and does it matter?

Articles

The role of ligand-gated conformational changes in enzyme catalysis

Cátia Moreira, Ana Rita Calixto, John P. Richard, Shina Caroline Lynn Kamerlin

Biochem Soc Trans (2019) 47 (5): 1449–1460.

DOI: https://doi.org/10.1042/BST20190298

Published: 28 October 2019

View article titled, The role of ligand-gated conformational changes in enzyme catalysis

Articles

Structural dynamics of P-type ATPase ion pumps

Mateusz Dyla, Sara Basse Hansen, Poul Nissen, Magnus Kjaergaard

Biochem Soc Trans (2019) 47 (5): 1247–1257.

DOI: https://doi.org/10.1042/BST20190124

Published: 11 October 2019

View article titled, Structural dynamics of P-type ATPase ion pumps

Articles

Making the cut(s): how Cas12a cleaves target and non-target DNA

Daan C. Swarts

Biochem Soc Trans (2019) 47 (5): 1499–1510.

DOI: https://doi.org/10.1042/BST20190564

Published: 11 October 2019

View article titled, Making the cut(s): how Cas12a cleaves target and non-target DNA

Articles

The missing link: allostery and catalysis in the anti-viral protein SAMHD1

Elizabeth R. Morris, Ian A. Taylor

Biochem Soc Trans (2019) 47 (4): 1013–1027.

DOI: https://doi.org/10.1042/BST20180348

Published: 11 July 2019

View article titled, The missing link: allostery and catalysis in the anti-viral protein SAMHD1

Articles

PseudoGTPase domains in p190RhoGAP proteins: a mini-review

Amy L. Stiegler, Titus J. Boggon

Biochem Soc Trans (2018) 46 (6): 1713–1720.

DOI: https://doi.org/10.1042/BST20180481

Published: 04 December 2018

View article titled, PseudoGTPase domains in p190RhoGAP proteins: a mini-review

Articles

The regulatory role of the kinase-homology domain in receptor guanylyl cyclases: nothing ‘pseudo’ about it!

Vishwas Mishra, Ridhima Goel, Sandhya S. Visweswariah

Biochem Soc Trans (2018) 46 (6): 1729–1742.

DOI: https://doi.org/10.1042/BST20180472

Published: 12 November 2018

View article titled, The regulatory role of the kinase-homology domain in receptor guanylyl cyclases: nothing ‘pseudo’ about it!

Articles

Metallocluster transactions: dynamic protein interactions guide the biosynthesis of Fe–S clusters in bacteria

Chenkang Zheng, Patricia C. Dos Santos

Biochem Soc Trans (2018) 46 (6): 1593–1603.

DOI: https://doi.org/10.1042/BST20180365

Published: 31 October 2018

View article titled, Metallocluster transactions: dynamic protein interactions guide the biosynthesis of Fe–S clusters in bacteria

Articles

Recent insights into lytic polysaccharide monooxygenases (LPMOs)

Tobias Tandrup, Kristian E. H. Frandsen, Katja S. Johansen, Jean-Guy Berrin, Leila Lo Leggio

Biochem Soc Trans (2018) 46 (6): 1431–1447.

DOI: https://doi.org/10.1042/BST20170549

Published: 31 October 2018

View article titled, Recent insights into lytic polysaccharide monooxygenases (LPMOs)

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