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Eliminating oncogenic RAS: back to the future at the drawing board

Candy Laura Steffen, Pelin Kaya, Elisabeth Schaffner-Reckinger, Daniel Abankwa

Biochem Soc Trans (2023) BST20221343.

DOI: https://doi.org/10.1042/BST20221343

Published: 23 January 2023

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Includes: Supplementary data

Articles

Therapeutic targeting of eukaryotic initiation factor (eIF) 4E

Jerry Pelletier, Nahum Sonenberg

Biochem Soc Trans (2023) BST20220285.

DOI: https://doi.org/10.1042/BST20220285

Published: 20 January 2023

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Articles

G4-interacting proteins endangering genomic stability at G4 DNA-forming sites

Nayun Kim

Biochem Soc Trans (2023) BST20221018.

DOI: https://doi.org/10.1042/BST20221018

Published: 11 January 2023

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Articles

Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery

Lionel Urán Landaburu, Mercedes Didier Garnham, Fernán Agüero

Biochem Soc Trans (2023) BST20220618.

DOI: https://doi.org/10.1042/BST20220618

Published: 06 January 2023

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Articles

Interactions governing transcriptional activity of nuclear receptors

Sabab Hasan Khan, C. Denise Okafor

Biochem Soc Trans (2022) 50 (6): 1941–1952.

DOI: https://doi.org/10.1042/BST20220338

Published: 16 December 2022

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Articles

LncRNA: a new perspective on the study of neurological diseases

Yun Ma, Siqi He, Tianhe Gu, Yixuan Liu, Shuya He, Zhisheng Jiang

Biochem Soc Trans (2022) 50 (2): 951–963.

DOI: https://doi.org/10.1042/BST20211181

Published: 06 April 2022

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Articles

Cofactor F 420 , an emerging redox power in biosynthesis of secondary metabolites

Ghader Bashiri

Biochem Soc Trans (2022) 50 (1): 253–267.

DOI: https://doi.org/10.1042/BST20211286

Published: 22 February 2022

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Articles

Tyrosine- O -sulfation is a widespread affinity enhancer among thrombin interactors

Jorge Ripoll-Rozada, Joshua W. C. Maxwell, Richard J. Payne, Pedro José Barbosa Pereira

Biochem Soc Trans (2022) 50 (1): 387–401.

DOI: https://doi.org/10.1042/BST20210600

Published: 07 January 2022

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Articles

Writing and erasing O- GlcNAc from target proteins in cells

Yun Ge, Christina M. Woo

Biochem Soc Trans (2021) 49 (6): 2891–2901.

DOI: https://doi.org/10.1042/BST20210865

Published: 16 November 2021

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Articles

Live-cell visualization of cytochrome c : a tool to explore apoptosis

João Pessoa

Biochem Soc Trans (2021) 49 (6): 2903–2915.

DOI: https://doi.org/10.1042/BST20211028

Published: 08 November 2021

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Articles

Structural insights into glucocorticoid receptor function

Filipp Frank, Eric A. Ortlund, Xu Liu

Biochem Soc Trans (2021) 49 (5): 2333–2343.

DOI: https://doi.org/10.1042/BST20210419

Published: 28 October 2021

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Articles

Chemical biology approaches to study histone interactors

Antony J. Burton, Ghaith M. Hamza, Andrew X. Zhang, Tom W. Muir

Biochem Soc Trans (2021) 49 (5): 2431–2441.

DOI: https://doi.org/10.1042/BST20210772

Published: 28 October 2021

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Articles

Controlled metabolic cascades for protein synthesis in an artificial cell

Huong Thanh Nguyen, Sungwoo Lee, Kwanwoo Shin

Biochem Soc Trans (2021) 49 (5): 2143–2151.

DOI: https://doi.org/10.1042/BST20210175

Published: 08 October 2021

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Articles

The pockets guide to HLA class I molecules

Andrea T. Nguyen, Christopher Szeto, Stephanie Gras

Biochem Soc Trans (2021) 49 (5): 2319–2331.

DOI: https://doi.org/10.1042/BST20210410

Published: 28 September 2021

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Articles

Discovery, development and application of drugs targeting BCL-2 pro-survival proteins in cancer

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Cell death and survival

Erinna F. Lee, W. Douglas Fairlie

Biochem Soc Trans (2021) 49 (5): 2381–2395.

DOI: https://doi.org/10.1042/BST20210749

Published: 13 September 2021

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Articles

Semi- and fully synthetic carbohydrate vaccines against pathogenic bacteria: recent developments

Magdalena E. Zasłona, A. Michael Downey, Peter H. Seeberger, Oren Moscovitz

Biochem Soc Trans (2021) 49 (5): 2411–2429.

DOI: https://doi.org/10.1042/BST20210766

Published: 08 September 2021

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Articles

Functional interrogation and therapeutic targeting of protein tyrosine phosphatases

Aaron D. Krabill, Zhong-Yin Zhang

Biochem Soc Trans (2021) 49 (4): 1723–1734.

DOI: https://doi.org/10.1042/BST20201308

Published: 25 August 2021

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Articles

Exploring chromatin structural roles of non-coding RNAs at imprinted domains

David Llères, Yui Imaizumi, Robert Feil

Biochem Soc Trans (2021) 49 (4): 1867–1879.

DOI: https://doi.org/10.1042/BST20210758

Published: 02 August 2021

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Articles

Unravelling the structural complexity of protein–lipid interactions with neutron reflectometry

Luke A. Clifton

Biochem Soc Trans (2021) 49 (4): 1537–1546.

DOI: https://doi.org/10.1042/BST20201071

Published: 09 July 2021

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Articles

Progress in the therapeutic inhibition of Cdc42 signalling

Natasha P. Murphy, Helen R. Mott, Darerca Owen

Biochem Soc Trans (2021) 49 (3): 1443–1456.

DOI: https://doi.org/10.1042/BST20210112

Published: 08 June 2021

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Articles

Chemical reporters to study mammalian O-glycosylation

Kathryn E. Huxley, Lianne I. Willems

Biochem Soc Trans (2021) 49 (2): 903–913.

DOI: https://doi.org/10.1042/BST20200839

Published: 16 April 2021

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Articles

Combinatorial biosynthesis for the generation of new-to-nature peptide antimicrobials

Fleur Ruijne, Oscar P. Kuipers

Biochem Soc Trans (2021) 49 (1): 203–215.

DOI: https://doi.org/10.1042/BST20200425

Published: 13 January 2021

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Articles

Inhibition of RAF dimers: it takes two to tango

Frazer A. Cook, Simon J. Cook

Biochem Soc Trans (2021) 49 (1): 237–251.

DOI: https://doi.org/10.1042/BST20200485

Published: 24 December 2020

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Articles

Protein–membrane interactions in small GTPase signalling and pharmacology: perspectives from Arf GTPases studies

Agata Nawrotek, Mahel Zeghouf, Jacqueline Cherfils

Biochem Soc Trans (2020) 48 (6): 2721–2728.

DOI: https://doi.org/10.1042/BST20200482

Published: 18 December 2020

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Articles

Multifunctionality of F-rich nucleoporins

Nike Heinß, Mikhail Sushkin, Miao Yu, Edward A. Lemke

Biochem Soc Trans (2020) 48 (6): 2603–2614.

DOI: https://doi.org/10.1042/BST20200357

Published: 18 December 2020

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Articles

Engineering with NanoLuc: a playground for the development of bioluminescent protein switches and sensors

Lieuwe Biewenga, Bas J.H.M. Rosier, Maarten Merkx

Biochem Soc Trans (2020) 48 (6): 2643–2655.

DOI: https://doi.org/10.1042/BST20200440

Published: 26 November 2020

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Articles

Fluorescent proteins for in vivo imaging, where's the biliverdin?

Felipe Montecinos-Franjola, John Y. Lin, Erik A. Rodriguez

Biochem Soc Trans (2020) 48 (6): 2657–2667.

DOI: https://doi.org/10.1042/BST20200444

Published: 16 November 2020

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Articles

Studying the surfaces of bacteria using neutron scattering: finding new openings for antibiotics

Nicolò Paracini, Luke A. Clifton, Jeremy H. Lakey

Biochem Soc Trans (2020) 48 (5): 2139–2149.

DOI: https://doi.org/10.1042/BST20200320

Published: 02 October 2020

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Articles

The tryptophan biosynthetic pathway is essential for Mycobacterium tuberculosis to cause disease

J. Shaun Lott

Biochem Soc Trans (2020) 48 (5): 2029–2037.

DOI: https://doi.org/10.1042/BST20200194

Published: 11 September 2020

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Articles

Small molecule ERK5 kinase inhibitors paradoxically activate ERK5 signalling: be careful what you wish for…

Simon J. Cook, Julie A. Tucker, Pamela A. Lochhead

Biochem Soc Trans (2020) 48 (5): 1859–1875.

DOI: https://doi.org/10.1042/BST20190338

Published: 11 September 2020

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Articles

Current problems and future avenues in proteoliposome research

Andrea Marco Amati, Simone Graf, Sabina Deutschmann, Nicolas Dolder, Christoph von Ballmoos

Biochem Soc Trans (2020) 48 (4): 1473–1492.

DOI: https://doi.org/10.1042/BST20190966

Published: 24 August 2020

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Articles

Genetically encoded selective cross-linkers and emerging applications

Haiyan Ren

Biochem Soc Trans (2020) 48 (4): 1807–1817.

DOI: https://doi.org/10.1042/BST20200508

Published: 13 July 2020

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Articles

Controlling gene expression with light: a multidisciplinary endeavour

In Collection

Awards

Denis Hartmann, Jefferson M. Smith, Giacomo Mazzotti, Razia Chowdhry, Michael J. Booth

Biochem Soc Trans (2020) 48 (4): 1645–1659.

DOI: https://doi.org/10.1042/BST20200014

Published: 13 July 2020

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Articles

Engineered peptide ligases for cell signaling and bioconjugation

Clara L. Frazier, Amy M. Weeks

Biochem Soc Trans (2020) 48 (3): 1153–1165.

DOI: https://doi.org/10.1042/BST20200001

Published: 15 June 2020

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Articles

α-glucosidase inhibitors as host-directed antiviral agents with potential for the treatment of COVID-19

In Collection

Coronavirus

Spencer J. Williams, Ethan D. Goddard-Borger

Biochem Soc Trans (2020) 48 (3): 1287–1295.

DOI: https://doi.org/10.1042/BST20200505

Published: 08 June 2020

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Articles

Small molecules that target the ubiquitin system

Hai Qiu Wu, David Baker, Huib Ovaa

Biochem Soc Trans (2020) 48 (2): 479–497.

DOI: https://doi.org/10.1042/BST20190535

Published: 20 March 2020

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Articles

The role of ligand-gated conformational changes in enzyme catalysis

Cátia Moreira, Ana Rita Calixto, John P. Richard, Shina Caroline Lynn Kamerlin

Biochem Soc Trans (2019) 47 (5): 1449–1460.

DOI: https://doi.org/10.1042/BST20190298

Published: 28 October 2019

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Articles

The fitness challenge of studying molecular adaptation

David Coombes, James W.B. Moir, Anthony M. Poole, Tim F. Cooper, Renwick C.J. Dobson

Biochem Soc Trans (2019) 47 (5): 1533–1542.

DOI: https://doi.org/10.1042/BST20180626

Published: 23 October 2019

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Articles

Selective small-molecule EPAC activators

Urszula Luchowska-Stańska, David Morgan, Stephen J. Yarwood, Graeme Barker

Biochem Soc Trans (2019) 47 (5): 1415–1427.

DOI: https://doi.org/10.1042/BST20190254

Published: 11 October 2019

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Articles

Fostering open collaboration in drug development for paediatric brain tumours

Jong Fu Wong, Elizabeth J. Brown, Eleanor Williams, Alex N. Bullock

Biochem Soc Trans (2019) 47 (5): 1471–1479.

DOI: https://doi.org/10.1042/BST20190315

Published: 24 September 2019

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Articles

Carcinogens and DNA damage

Jessica L. Barnes, Maria Zubair, Kaarthik John, Miriam C. Poirier, Francis L. Martin

Biochem Soc Trans (2018) 46 (5): 1213–1224.

DOI: https://doi.org/10.1042/BST20180519

Published: 04 October 2018

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Articles

Do nitric oxide, carbon monoxide and hydrogen sulfide really qualify as ‘gasotransmitters’ in bacteria?

Lauren K. Wareham, Hannah M. Southam, Robert K. Poole

Biochem Soc Trans (2018) 46 (5): 1107–1118.

DOI: https://doi.org/10.1042/BST20170311

Published: 06 September 2018

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Articles

Bacterial zinc uptake regulator proteins and their regulons

Alevtina Mikhaylina, Amira Z. Ksibe, David J. Scanlan, Claudia A. Blindauer

Biochem Soc Trans (2018) 46 (4): 983–1001.

DOI: https://doi.org/10.1042/BST20170228

Published: 31 July 2018

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Articles

Coenzyme A, protein CoAlation and redox regulation in mammalian cells

Ivan Gout

Biochem Soc Trans (2018) 46 (3): 721–728.

DOI: https://doi.org/10.1042/BST20170506

Published: 25 May 2018

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Articles

Probing ubiquitin and SUMO conjugation and deconjugation

Huib Ovaa, Alfred C.O. Vertegaal

Biochem Soc Trans (2018) 46 (2): 423–436.

DOI: https://doi.org/10.1042/BST20170086

Published: 27 March 2018

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Articles

The fumarylacetoacetate hydrolase (FAH) superfamily of enzymes: multifunctional enzymes from microbes to mitochondria

Alexander K.H. Weiss, Johannes R. Loeffler, Klaus R. Liedl, Hubert Gstach, Pidder Jansen-Dürr

Biochem Soc Trans (2018) 46 (2): 295–309.

DOI: https://doi.org/10.1042/BST20170518

Published: 27 February 2018

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Includes: Supplementary data

Articles

Mass spectrometry techniques for studying the ubiquitin system

Rachel E. Heap, Megan S. Gant, Frederic Lamoliatte, Julien Peltier, Matthias Trost

Biochem Soc Trans (2017) 45 (5): 1137–1148.

DOI: https://doi.org/10.1042/BST20170091

Published: 22 September 2017

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Articles

Structure and function of DHHC protein S -acyltransferases

Colin D. Gottlieb, Maurine E. Linder

Biochem Soc Trans (2017) 45 (4): 923–928.

DOI: https://doi.org/10.1042/BST20160304

Published: 16 June 2017

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Articles

Substrate selectivity in the zDHHC family of S -acyltransferases

Kimon Lemonidis, Christine Salaun, Marianna Kouskou, Cinta Diez-Ardanuy, Luke H. Chamberlain, Jennifer Greaves

Biochem Soc Trans (2017) 45 (3): 751–758.

DOI: https://doi.org/10.1042/BST20160309

Published: 15 June 2017

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Articles

How RNA acts as a nuclease: some mechanistic comparisons in the nucleolytic ribozymes

David M.J. Lilley

Biochem Soc Trans (2017) 45 (3): 683–691.

DOI: https://doi.org/10.1042/BST20160158

Published: 15 June 2017

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