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Articles

Structures and coordination chemistry of transporters involved in manganese and iron homeostasis

Shamayeeta Ray, Rachelle Gaudet
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) BST20210699.
DOI: https://doi.org/10.1042/BST20210699
Published: 07 June 2023
View article titled, Structures and coordination chemistry of transporters involved in manganese and iron homeostasis
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Articles

Caveolae and the oxidative stress response

Yeping Wu, Ye-Wheen Lim, Robert G. Parton
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) BST20230121.
DOI: https://doi.org/10.1042/BST20230121
Published: 30 May 2023
View article titled, Caveolae and the oxidative stress response
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Articles

The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis

Fabian Gude, Jurij Froese, Georg Steffes, Kay Grobe
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) BST20220719.
DOI: https://doi.org/10.1042/BST20220719
Published: 24 May 2023
View article titled, The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis
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Articles

The multiple ubiquitination mechanisms in CFTR peripheral quality control

Shogo Taniguchi, Ryosuke Fukuda, Tsukasa Okiyoneda
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) BST20221468.
DOI: https://doi.org/10.1042/BST20221468
Published: 04 May 2023
View article titled, The multiple ubiquitination mechanisms in CFTR peripheral quality control
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Articles

The building blocks of caveolae revealed: caveolins finally take center stage

Anne K. Kenworthy
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 855–869.
DOI: https://doi.org/10.1042/BST20221298
Published: 21 April 2023
View article titled, The building blocks of caveolae revealed: caveolins finally take center stage
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Articles

What voltage-sensing phosphatases can reveal about the mechanisms of ion channel regulation by phosphoinositides

Yasushi Okamura, Daisuke Yoshioka
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 827–839.
DOI: https://doi.org/10.1042/BST20221065
Published: 13 April 2023
View article titled, What voltage-sensing phosphatases can reveal about the mechanisms of ion channel regulation by phosphoinositides
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Articles

New discoveries in ER–mitochondria communication

Margret Helene Bülow, Julia Sellin
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 571–577.
DOI: https://doi.org/10.1042/BST20221305
Published: 09 March 2023
View article titled, New discoveries in ER–mitochondria communication
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Articles

The role of CaMKK2 in Golgi-associated vesicle trafficking

Grace Kennedy, Olivia Gibson, Dáire T. O'Hare, Ian G. Mills, Emma Evergren
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 331–342.
DOI: https://doi.org/10.1042/BST20220833
Published: 23 February 2023
View article titled, The role of CaMKK2 in Golgi-associated vesicle trafficking
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Articles

The mechanisms of alkali therapy in targeting renal diseases

Pedro Henrique Imenez Silva, Donald E. Wesson, Carsten A. Wagner
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 223–232.
DOI: https://doi.org/10.1042/BST20220690
Published: 06 February 2023
View article titled, The mechanisms of alkali therapy in targeting renal diseases
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Articles

Lumenal components of cytoplasmic microtubules

Chisato Tsuji, Mark P. Dodding
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1953–1962.
DOI: https://doi.org/10.1042/BST20220851
Published: 16 December 2022
View article titled, Lumenal components of cytoplasmic microtubules
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Articles

The mechanisms of chromogranin B-regulated Cl − homeostasis

Qiu-Xing Jiang, Gaya Yadav
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1659–1672.
DOI: https://doi.org/10.1042/BST20220435
Published: 13 December 2022
View article titled, The mechanisms of chromogranin B-regulated Cl − homeostasis
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Articles

Placental extracellular vesicles in maternal-fetal communication during pregnancy

Charlène Martin, Mathilde Bergamelli, Cécile E. Malnou, Gisela D'Angelo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1785–1795.
DOI: https://doi.org/10.1042/BST20220734
Published: 09 December 2022
View article titled, Placental extracellular vesicles in maternal-fetal communication during pregnancy
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Articles

Mitolysosome exocytosis: a novel mitochondrial quality control pathway linked with parkinsonism-like symptoms

Feixiang Bao, Lingyan Zhou, Jiahui Xiao, Xingguo Liu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1773–1783.
DOI: https://doi.org/10.1042/BST20220726
Published: 09 December 2022
View article titled, Mitolysosome exocytosis: a novel mitochondrial quality control pathway linked with parkinsonism-like symptoms
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Articles

Structure and function of the peroxisomal ubiquitin ligase complex

Peiqiang Feng, Michael L. Skowyra, Tom A. Rapoport
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1921–1930.
DOI: https://doi.org/10.1042/BST20221393
Published: 24 November 2022
View article titled, Structure and function of the peroxisomal ubiquitin ligase complex
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Articles

Fundamental roles for inter-organelle communication in aging

Eric K. F. Donahue, Elizabeth M. Ruark, Kristopher Burkewitz
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1389–1402.
DOI: https://doi.org/10.1042/BST20220519
Published: 28 October 2022
View article titled, Fundamental roles for inter-organelle communication in aging
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Articles

Strength in numbers: effect of protein crowding on the shape of cell membranes

Victoria Thusgaard Ruhoff, Guillermo Moreno-Pescador, Weria Pezeshkian, Poul Martin Bendix
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1257–1267.
DOI: https://doi.org/10.1042/BST20210883
Published: 10 October 2022
View article titled, Strength in numbers: effect of protein crowding on the shape of cell membranes
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Articles

The functional importance of VCP to maintaining cellular protein homeostasis

Brittany A. Ahlstedt, Rakesh Ganji, Malavika Raman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1457–1469.
DOI: https://doi.org/10.1042/BST20220648
Published: 05 October 2022
View article titled, The functional importance of VCP to maintaining cellular protein homeostasis
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Articles

Propagation of Parkinson's disease by extracellular vesicle production and secretion

Laura E. Shippey, Susan G. Campbell, Andrew F. Hill, David P. Smith
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1303–1314.
DOI: https://doi.org/10.1042/BST20220204
Published: 16 September 2022
View article titled, Propagation of Parkinson's disease by extracellular vesicle production and secretion
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Articles

Studying actin-induced cell shape changes using Giant Unilamellar Vesicles and reconstituted actin networks

Rogério Lopes dos Santos, Clément Campillo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1527–1539.
DOI: https://doi.org/10.1042/BST20220900
Published: 16 September 2022
View article titled, Studying actin-induced cell shape changes using Giant Unilamellar Vesicles and reconstituted actin networks
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Articles

Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques

Chung Yu Chan, Youssef Faragalla, Ling-Gang Wu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (4): 1157–1167.
DOI: https://doi.org/10.1042/BST20210263
Published: 12 August 2022
View article titled, Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques
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Articles

Two-pore channels: going with the flows

Anthony J. Morgan, Lora L. Martucci, Lianne C. Davis, Antony Galione
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (4): 1143–1155.
DOI: https://doi.org/10.1042/BST20220229
Published: 12 August 2022
View article titled, Two-pore channels: going with the flows
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Articles

Clusters of apoptotic signaling molecule-enriched rafts, CASMERs: membrane platforms for protein assembly in Fas/CD95 signaling and targets in cancer therapy

In Collection
Cell death and survival
Faustino Mollinedo, Consuelo Gajate
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1105–1118.
DOI: https://doi.org/10.1042/BST20211115
Published: 19 May 2022
View article titled, Clusters of apoptotic signaling molecule-enriched rafts, CASMERs: membrane platforms for protein assembly in Fas/CD95 signaling and targets in cancer therapy
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Articles

New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease

In Collection
Awards
Valerie B. O'Donnell
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 1–11.
DOI: https://doi.org/10.1042/BST20210579
Published: 28 February 2022
View article titled, New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease
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Articles

How lipids affect the energetics of co-translational alpha helical membrane protein folding

Ryan Brady, Nicola J. Harris, Grant A. Pellowe, Samuel Gulaidi Breen, Paula J. Booth
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 555–567.
DOI: https://doi.org/10.1042/BST20201063
Published: 25 February 2022
View article titled, How lipids affect the energetics of co-translational alpha helical membrane protein folding
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Articles

Bile acid metabolism and FXR-mediated effects in human cholestatic liver disorders

Antonio Molinaro, Hanns-Ulrich Marschall
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 361–373.
DOI: https://doi.org/10.1042/BST20210658
Published: 22 February 2022
View article titled, Bile acid metabolism and FXR-mediated effects in human cholestatic liver disorders
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Articles

Non-canonical roles of ATG8 for TFEB activation

In Collection
Cell death and survival
Shuhei Nakamura, Shiori Akayama, Tamotsu Yoshimori
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 47–54.
DOI: https://doi.org/10.1042/BST20210813
Published: 15 February 2022
View article titled, Non-canonical roles of ATG8 for TFEB activation
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Articles

Three-dimensional insights into human enveloped viruses in vitro and in situ

Naveen Vankadari, Doulin C. Shepherd, Stephen D. Carter, Debnath Ghosal
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 95–105.
DOI: https://doi.org/10.1042/BST20210433
Published: 25 January 2022
View article titled, Three-dimensional insights into human enveloped viruses in vitro and in situ
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Articles

Molecular regulation of autophagosome formation

In Collection
Cell death and survival
Yan Hu, Fulvio Reggiori
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 55–69.
DOI: https://doi.org/10.1042/BST20210819
Published: 25 January 2022
View article titled, Molecular regulation of autophagosome formation
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Articles

Structural and functional approaches to studying cAMP regulation of HCN channels

Andrea Saponaro, Gerhard Thiel, Anna Moroni
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2573–2579.
DOI: https://doi.org/10.1042/BST20210290
Published: 23 November 2021
View article titled, Structural and functional approaches to studying cAMP regulation of HCN channels
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Articles

Applications of Cryo-EM in small molecule and biologics drug design

Joshua A. Lees, Joao M. Dias, Seungil Han
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2627–2638.
DOI: https://doi.org/10.1042/BST20210444
Published: 23 November 2021
View article titled, Applications of Cryo-EM in small molecule and biologics drug design
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Articles

The dynamics of mitochondrial autophagy at the initiation stage

Nicholas T. Ktistakis
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2199–2210.
DOI: https://doi.org/10.1042/BST20210272
Published: 19 October 2021
View article titled, The dynamics of mitochondrial autophagy at the initiation stage
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Articles

Ca 2+ -dependent modulation of voltage-gated myocyte sodium channels

Samantha C. Salvage, Zaki F. Habib, Hugh R. Matthews, Antony P. Jackson, Christopher L.-H. Huang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 1941–1961.
DOI: https://doi.org/10.1042/BST20200604
Published: 13 October 2021
View article titled, Ca 2+ -dependent modulation of voltage-gated myocyte sodium channels
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Articles

Biophysical characterisation of SMALPs

Stephanie A. Nestorow, Tim R. Dafforn, Verna Frasca
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2037–2050.
DOI: https://doi.org/10.1042/BST20201088
Published: 13 October 2021
View article titled, Biophysical characterisation of SMALPs
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Articles

Dispatching plasma membrane cholesterol and Sonic Hedgehog dispatch: two sides of the same coin?

Kristina Ehring, Kay Grobe
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2455–2463.
DOI: https://doi.org/10.1042/BST20210918
Published: 13 September 2021
View article titled, Dispatching plasma membrane cholesterol and Sonic Hedgehog dispatch: two sides of the same coin?
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Articles

Correlative nanophotonic approaches to enlighten the nanoscale dynamics of living cell membranes

Pamina M. Winkler, María F. García-Parajo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2357–2369.
DOI: https://doi.org/10.1042/BST20210457
Published: 08 September 2021
View article titled, Correlative nanophotonic approaches to enlighten the nanoscale dynamics of living cell membranes
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Articles

Lipid–protein interactions in virus assembly and budding from the host cell plasma membrane

Balindile B. Motsa, Robert V. Stahelin
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1633–1641.
DOI: https://doi.org/10.1042/BST20200854
Published: 25 August 2021
View article titled, Lipid–protein interactions in virus assembly and budding from the host cell plasma membrane
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Articles

Methods for the solubilisation of membrane proteins: the micelle-aneous world of membrane protein solubilisation

Giedre Ratkeviciute, Benjamin F. Cooper, Timothy J. Knowles
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1763–1777.
DOI: https://doi.org/10.1042/BST20210181
Published: 20 August 2021
View article titled, Methods for the solubilisation of membrane proteins: the micelle-aneous world of membrane protein solubilisation
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Articles

Ion channels as convergence points in the pathology of pulmonary arterial hypertension

Thibault R. H. Jouen-Tachoire, Stephen J. Tucker, Paolo Tammaro
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1855–1865.
DOI: https://doi.org/10.1042/BST20210538
Published: 04 August 2021
View article titled, Ion channels as convergence points in the pathology of pulmonary arterial hypertension
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Articles

Single-molecule fluorescence vistas of how lipids regulate membrane proteins

Alyssa E. Ward, Yujie Ye, Jennifer A. Schuster, Shushu Wei, Francisco N. Barrera
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1685–1694.
DOI: https://doi.org/10.1042/BST20201074
Published: 04 August 2021
View article titled, Single-molecule fluorescence vistas of how lipids regulate membrane proteins
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Articles

Unravelling the structural complexity of protein–lipid interactions with neutron reflectometry

Luke A. Clifton
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1537–1546.
DOI: https://doi.org/10.1042/BST20201071
Published: 09 July 2021
View article titled, Unravelling the structural complexity of protein–lipid interactions with neutron reflectometry
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Articles

Biological insights from SMA-extracted proteins

Lucas Unger, Alejandro Ronco-Campaña, Philip Kitchen, Roslyn M. Bill, Alice J. Rothnie
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (3): 1349–1359.
DOI: https://doi.org/10.1042/BST20201067
Published: 10 June 2021
View article titled, Biological insights from SMA-extracted proteins
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Articles

Root hairs: the villi of plants

Manuela Désirée Bienert, Lena M. Werner, Monika A. Wimmer, Gerd Patrick Bienert
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (3): 1133–1146.
DOI: https://doi.org/10.1042/BST20200716
Published: 20 May 2021
View article titled, Root hairs: the villi of plants
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Articles

Roles of interstitial fluid pH and weak organic acids in development and amelioration of insulin resistance

Yoshinori Marunaka
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 715–726.
DOI: https://doi.org/10.1042/BST20200667
Published: 26 March 2021
View article titled, Roles of interstitial fluid pH and weak organic acids in development and amelioration of insulin resistance
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Articles

Mechanisms of mitochondrial cell death

In Collection
Cell death and survival
Shashank Dadsena, Cristiana Zollo, Ana J. García-Sáez
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 663–674.
DOI: https://doi.org/10.1042/BST20200522
Published: 11 March 2021
View article titled, Mechanisms of mitochondrial cell death
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Articles

Class II phosphatidylinositol 3-kinase isoforms in vesicular trafficking

Kazuaki Yoshioka
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 893–901.
DOI: https://doi.org/10.1042/BST20200835
Published: 05 March 2021
View article titled, Class II phosphatidylinositol 3-kinase isoforms in vesicular trafficking
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Articles

HTR6 and SSTR3 targeting to primary cilia

Pablo Barbeito, Francesc R. Garcia-Gonzalo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 79–91.
DOI: https://doi.org/10.1042/BST20191005
Published: 18 February 2021
View article titled, HTR6 and SSTR3 targeting to primary cilia
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Articles

Endothelial response to glucose: dysfunction, metabolism, and transport

Alisa Morss Clyne
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 313–325.
DOI: https://doi.org/10.1042/BST20200611
Published: 01 February 2021
View article titled, Endothelial response to glucose: dysfunction, metabolism, and transport
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Articles

RNA transfer through tunneling nanotubes

Gal Haimovich, Sandipan Dasgupta, Jeffrey E. Gerst
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 145–160.
DOI: https://doi.org/10.1042/BST20200113
Published: 24 December 2020
View article titled, RNA transfer through tunneling nanotubes
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Articles

Protein–membrane interactions in small GTPase signalling and pharmacology: perspectives from Arf GTPases studies

Agata Nawrotek, Mahel Zeghouf, Jacqueline Cherfils
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (6): 2721–2728.
DOI: https://doi.org/10.1042/BST20200482
Published: 18 December 2020
View article titled, Protein–membrane interactions in small GTPase signalling and pharmacology: perspectives from Arf GTPases studies
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Articles

Intrinsically disordered proteins and membranes: a marriage of convenience for cell signalling?

Jasmine Cornish, Samuel G. Chamberlain, Darerca Owen, Helen R. Mott
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (6): 2669–2689.
DOI: https://doi.org/10.1042/BST20200467
Published: 06 November 2020
View article titled, Intrinsically disordered proteins and membranes: a marriage of convenience for cell signalling?
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