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Articles

Caveolae and the oxidative stress response

Yeping Wu, Ye-Wheen Lim, Robert G. Parton

Biochem Soc Trans (2023) BST20230121.

DOI: https://doi.org/10.1042/BST20230121

Published: 30 May 2023

View article titled, Caveolae and the oxidative stress response

Articles

Messenger functions of cell death during development and homeostasis

Loic Fort

Biochem Soc Trans (2023) 51 (2): 759–769.

DOI: https://doi.org/10.1042/BST20220925

Published: 06 April 2023

View article titled, Messenger functions of cell death during development and homeostasis

Articles

The role of the blood–brain barrier during neurological disease and infection

Adjanie Patabendige, Damir Janigro

Biochem Soc Trans (2023) 51 (2): 613–626.

DOI: https://doi.org/10.1042/BST20220830

Published: 17 March 2023

View article titled, The role of the blood–brain barrier during neurological disease and infection

Articles

Mitochondrial DNA in cell death and inflammation

In Collection

Cell death and survival

Rosalie Heilig, Jordan Lee, Stephen W.G. Tait

Biochem Soc Trans (2023) 51 (1): 457–472.

DOI: https://doi.org/10.1042/BST20221525

Published: 23 February 2023

View article titled, Mitochondrial DNA in cell death and inflammation

Articles

Targeting NRF2 to promote epithelial repair

Paul Hiebert, Sabine Werner

Biochem Soc Trans (2023) 51 (1): 101–111.

DOI: https://doi.org/10.1042/BST20220228

Published: 10 February 2023

View article titled, Targeting NRF2 to promote epithelial repair

Articles

Inflammatory cell death: how macrophages sense neighbouring cell infection and damage

Xiaohui Wang, Larisa I. Labzin

Biochem Soc Trans (2023) 51 (1): 303–313.

DOI: https://doi.org/10.1042/BST20220807

Published: 25 January 2023

View article titled, Inflammatory cell death: how macrophages sense neighbouring cell infection and damage

Articles

CD95/Fas ligand induced toxicity

In Collection

Cell death and survival

Ashley Haluck-Kangas, Marcus E. Peter

Biochem Soc Trans (2023) 51 (1): 21–29.

DOI: https://doi.org/10.1042/BST20211187

Published: 11 January 2023

View article titled, CD95/Fas ligand induced toxicity

Articles

Therapeutic targeting of TRAIL death receptors

In Collection

Cell death and survival

Francesca Di Cristofano, Andrew George, Vida Tajiknia, Maryam Ghandali, Laura Wu, Yiqun Zhang, Praveen Srinivasan, Jillian Strandberg, Marina Hahn, Ashley Sanchez Sevilla Uruchurtu, Attila A. Seyhan, Benedito A. Carneiro, Lanlan Zhou, Kelsey E. Huntington, Wafik S. El-Deiry

Biochem Soc Trans (2023) 51 (1): 57–70.

DOI: https://doi.org/10.1042/BST20220098

Published: 11 January 2023

View article titled, Therapeutic targeting of TRAIL death receptors

Articles

RIPK1 and RIPK3 in antibacterial defence

In Collection

Cell death and survival

Hui Wen Yeap, Kaiwen W. Chen

Biochem Soc Trans (2022) 50 (6): 1583–1594.

DOI: https://doi.org/10.1042/BST20211242

Published: 24 November 2022

View article titled, RIPK1 and RIPK3 in antibacterial defence

Articles

The diverse arsenal of type III CRISPR–Cas-associated CARF and SAVED effectors

Jurre A. Steens, Carl Raymund P. Salazar, Raymond H.J. Staals

Biochem Soc Trans (2022) 50 (5): 1353–1364.

DOI: https://doi.org/10.1042/BST20220289

Published: 25 October 2022

View article titled, The diverse arsenal of type III CRISPR–Cas-associated CARF and SAVED effectors

Articles

Mechanisms of germ cell survival and plasticity in Caenorhabditis elegans

Wei Cao, Roger Pocock

Biochem Soc Trans (2022) 50 (5): 1517–1526.

DOI: https://doi.org/10.1042/BST20220878

Published: 05 October 2022

View article titled, Mechanisms of germ cell survival and plasticity in Caenorhabditis elegans

Articles

The role of RHIM in necroptosis

In Collection

Cell death and survival

Theresa Riebeling, Ulrich Kunzendorf, Stefan Krautwald

Biochem Soc Trans (2022) 50 (4): 1197–1205.

DOI: https://doi.org/10.1042/BST20220535

Published: 30 August 2022

View article titled, The role of RHIM in necroptosis

Articles

Clusters of apoptotic signaling molecule-enriched rafts, CASMERs: membrane platforms for protein assembly in Fas/CD95 signaling and targets in cancer therapy

In Collection

Cell death and survival

Faustino Mollinedo, Consuelo Gajate

Biochem Soc Trans (2022) 50 (3): 1105–1118.

DOI: https://doi.org/10.1042/BST20211115

Published: 19 May 2022

View article titled, Clusters of apoptotic signaling molecule-enriched rafts, CASMERs: membrane platforms for protein assembly in Fas/CD95 signaling and targets in cancer therapy

Articles

MMP-7 marks severe pancreatic cancer and alters tumor cell signaling by proteolytic release of ectodomains

Steven R. Van Doren

Biochem Soc Trans (2022) 50 (2): 839–851.

DOI: https://doi.org/10.1042/BST20210640

Published: 28 March 2022

View article titled, MMP-7 marks severe pancreatic cancer and alters tumor cell signaling by proteolytic release of ectodomains

Articles

Linear ubiquitination in immune and neurodegenerative diseases, and beyond

In Collection

Cell death and survival

Fuminori Tokunaga, Fumiyo Ikeda

Biochem Soc Trans (2022) 50 (2): 799–811.

DOI: https://doi.org/10.1042/BST20211078

Published: 28 March 2022

View article titled, Linear ubiquitination in immune and neurodegenerative diseases, and beyond

Articles

PIDD1 in cell cycle control, sterile inflammation and cell death

In Collection

Cell death and survival

Elias S. Weiler, Tamas G. Szabo, Irmina Garcia-Carpio, Andreas Villunger

Biochem Soc Trans (2022) 50 (2): 813–824.

DOI: https://doi.org/10.1042/BST20211186

Published: 28 March 2022

View article titled, PIDD1 in cell cycle control, sterile inflammation and cell death

Articles

Therapeutic targeting of mitophagy in Parkinson's disease

In Collection

Cell death and survival

Shashank Masaldan, Sylvie Callegari, Grant Dewson

Biochem Soc Trans (2022) 50 (2): 783–797.

DOI: https://doi.org/10.1042/BST20211107

Published: 21 March 2022

View article titled, Therapeutic targeting of mitophagy in Parkinson's disease

Articles

Role of macrophage extracellular traps in innate immunity and inflammatory disease

In Collection

Cell death and survival

Kristian H. Rasmussen, Clare L. Hawkins

Biochem Soc Trans (2022) 50 (1): 21–32.

DOI: https://doi.org/10.1042/BST20210962

Published: 22 February 2022

View article titled, Role of macrophage extracellular traps in innate immunity and inflammatory disease

Articles

Rare catastrophes and evolutionary legacies: human germline gene variants in MLKL and the necroptosis signalling pathway

In Collection

Cell death and survival

Sarah E. Garnish, Joanne M. Hildebrand

Biochem Soc Trans (2022) 50 (1): 529–539.

DOI: https://doi.org/10.1042/BST20210517

Published: 15 February 2022

View article titled, Rare catastrophes and evolutionary legacies: human germline gene variants in MLKL and the necroptosis signalling pathway

Articles

A proteomic perspective on TNF-mediated signalling and cell death

In Collection

Cell death and survival

Maria C. Tanzer

Biochem Soc Trans (2022) 50 (1): 13–20.

DOI: https://doi.org/10.1042/BST20211114

Published: 15 February 2022

View article titled, A proteomic perspective on TNF-mediated signalling and cell death

Articles

Cardiac regeneration following myocardial infarction: the need for regeneration and a review of cardiac stromal cell populations used for transplantation

Rita Alonaizan, Carolyn Carr

Biochem Soc Trans (2022) 50 (1): 269–281.

DOI: https://doi.org/10.1042/BST20210231

Published: 07 February 2022

View article titled, Cardiac regeneration following myocardial infarction: the need for regeneration and a review of cardiac stromal cell populations used for transplantation

Articles

Identifying new molecular players in extracellular proteostasis

Sandeep Satapathy, Mark R. Wilson

Biochem Soc Trans (2022) 50 (1): 321–334.

DOI: https://doi.org/10.1042/BST20210369

Published: 23 December 2021

View article titled, Identifying new molecular players in extracellular proteostasis

Articles

The role of caspases as executioners of apoptosis

In Collection

Cell death and survival

Sharad Kumar, Loretta Dorstyn, Yoon Lim

Biochem Soc Trans (2022) 50 (1): 33–45.

DOI: https://doi.org/10.1042/BST20210751

Published: 23 December 2021

View article titled, The role of caspases as executioners of apoptosis

Articles

VDAC2 and the BCL-2 family of proteins

In Collection

Cell death and survival

Zheng Yuan, Grant Dewson, Peter E. Czabotar, Richard W. Birkinshaw

Biochem Soc Trans (2021) 49 (6): 2787–2795.

DOI: https://doi.org/10.1042/BST20210753

Published: 16 December 2021

View article titled, VDAC2 and the BCL-2 family of proteins

Articles

Molecular and structural aspects of gasdermin family pores and insights into gasdermin-elicited programmed cell death

In Collection

Cell death and survival

Ayesha Zahid, Hazrat Ismail, Tengchuan Jin

Biochem Soc Trans (2021) 49 (6): 2697–2710.

DOI: https://doi.org/10.1042/BST20210672

Published: 23 November 2021

View article titled, Molecular and structural aspects of gasdermin family pores and insights into gasdermin-elicited programmed cell death

Articles

Targeting the BCL-2-regulated apoptotic pathway for the treatment of solid cancers

In Collection

Cell death and survival

W. Douglas Fairlie, Erinna F. Lee

Biochem Soc Trans (2021) 49 (5): 2397–2410.

DOI: https://doi.org/10.1042/BST20210750

Published: 28 September 2021

View article titled, Targeting the BCL-2-regulated apoptotic pathway for the treatment of solid cancers

Articles

Discovery, development and application of drugs targeting BCL-2 pro-survival proteins in cancer

In Collection

Cell death and survival

Erinna F. Lee, W. Douglas Fairlie

Biochem Soc Trans (2021) 49 (5): 2381–2395.

DOI: https://doi.org/10.1042/BST20210749

Published: 13 September 2021

View article titled, Discovery, development and application of drugs targeting BCL-2 pro-survival proteins in cancer

Articles

LRRK2 along the Golgi and lysosome connection: a jamming situation

Giovanni Piccoli, Mattia Volta

Biochem Soc Trans (2021) 49 (5): 2063–2072.

DOI: https://doi.org/10.1042/BST20201146

Published: 08 September 2021

View article titled, LRRK2 along the Golgi and lysosome connection: a jamming situation

Articles

Musculoskeletal complications associated with pathological iron toxicity and its molecular mechanisms

Márcio Simão, M. Leonor Cancela

Biochem Soc Trans (2021) 49 (2): 747–759.

DOI: https://doi.org/10.1042/BST20200672

Published: 30 April 2021

View article titled, Musculoskeletal complications associated with pathological iron toxicity and its molecular mechanisms

Articles

Phagocytic clearance of apoptotic, necrotic, necroptotic and pyroptotic cells

In Collection

Cell death and survival

Georgia K. Atkin-Smith

Biochem Soc Trans (2021) 49 (2): 793–804.

DOI: https://doi.org/10.1042/BST20200696

Published: 12 April 2021

View article titled, Phagocytic clearance of apoptotic, necrotic, necroptotic and pyroptotic cells

Articles

Mechanisms of mitochondrial cell death

In Collection

Cell death and survival

Shashank Dadsena, Cristiana Zollo, Ana J. García-Sáez

Biochem Soc Trans (2021) 49 (2): 663–674.

DOI: https://doi.org/10.1042/BST20200522

Published: 11 March 2021

View article titled, Mechanisms of mitochondrial cell death

Articles

Mitochondrial DNA in innate immune responses against infectious diseases

Palamou Das, Oishee Chakrabarti

Biochem Soc Trans (2020) 48 (6): 2823–2838.

DOI: https://doi.org/10.1042/BST20200687

Published: 06 November 2020

View article titled, Mitochondrial DNA in innate immune responses against infectious diseases

Articles

Emerging roles of lamins and DNA damage repair mechanisms in ovarian cancer

Duhita Sengupta, Asima Mukhopadhyay, Kaushik Sengupta

Biochem Soc Trans (2020) 48 (5): 2317–2333.

DOI: https://doi.org/10.1042/BST20200713

Published: 21 October 2020

View article titled, Emerging roles of lamins and DNA damage repair mechanisms in ovarian cancer

Articles

Emerging aspects in the regulation of ferroptosis

Helene Nehring, Svenja Meierjohann, Jose Pedro Friedmann Angeli

Biochem Soc Trans (2020) 48 (5): 2253–2259.

DOI: https://doi.org/10.1042/BST20200523

Published: 14 October 2020

View article titled, Emerging aspects in the regulation of ferroptosis

Articles

Splitting up to heal: mitochondrial shape regulates signaling for focal membrane repair

Adam Horn, Jyoti K. Jaiswal

Biochem Soc Trans (2020) 48 (5): 1995–2002.

DOI: https://doi.org/10.1042/BST20200120

Published: 28 September 2020

View article titled, Splitting up to heal: mitochondrial shape regulates signaling for focal membrane repair

Articles

Unleashing the therapeutic potential of apoptotic bodies

Thanh Kha Phan, Dilara Ceyda Ozkocak, Ivan Ka Ho Poon

Biochem Soc Trans (2020) 48 (5): 2079–2088.

DOI: https://doi.org/10.1042/BST20200225

Published: 01 September 2020

View article titled, Unleashing the therapeutic potential of apoptotic bodies

Articles

Hydrogen peroxide reactivity and specificity in thiol-based cell signalling

Christine C. Winterbourn

Biochem Soc Trans (2020) 48 (3): 745–754.

DOI: https://doi.org/10.1042/BST20190049

Published: 15 May 2020

View article titled, Hydrogen peroxide reactivity and specificity in thiol-based cell signalling

Articles

Cytotoxicity of snake venom enzymatic toxins: phospholipase A2 and l-amino acid oxidase

Jia Jin Hiu, Michelle Khai Khun Yap

Biochem Soc Trans (2020) 48 (2): 719–731.

DOI: https://doi.org/10.1042/BST20200110

Published: 08 April 2020

View article titled, Cytotoxicity of snake venom enzymatic toxins: phospholipase A2 and l-amino acid oxidase

Articles

The double-edged role of neutrophil extracellular traps in inflammation

Maximilien Euler, Markus H. Hoffmann

Biochem Soc Trans (2019) 47 (6): 1921–1930.

DOI: https://doi.org/10.1042/BST20190629

Published: 22 November 2019

View article titled, The double-edged role of neutrophil extracellular traps in inflammation

Articles

Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes

Mark A. Watson, Hoi-Shan Wong, Martin D. Brand

Biochem Soc Trans (2019) 47 (5): 1461–1469.

DOI: https://doi.org/10.1042/BST20190305

Published: 10 September 2019

View article titled, Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes

Articles

Structural snapshots of RAF kinase interactions

Soheila Rezaei Adariani, Marcel Buchholzer, Mohammad Akbarzadeh, Saeideh Nakhaei-Rad, Radovan Dvorsky, Mohammad Reza Ahmadian

Biochem Soc Trans (2018) 46 (6): 1393–1406.

DOI: https://doi.org/10.1042/BST20170528

Published: 31 October 2018

View article titled, Structural snapshots of RAF kinase interactions

Includes: Supplementary data

Articles

New perspectives on IL-33 and IL-1 family cytokines as innate environmental sensors

Ian C. Scott, D. Gareth Rees, E. Suzanne Cohen

Biochem Soc Trans (2018) 46 (5): 1345–1353.

DOI: https://doi.org/10.1042/BST20170567

Published: 09 October 2018

View article titled, New perspectives on IL-33 and IL-1 family cytokines as innate environmental sensors

Articles

The creatine kinase system as a therapeutic target for myocardial ischaemia–reperfusion injury

Fang Cao, Sevasti Zervou, Craig A. Lygate

Biochem Soc Trans (2018) 46 (5): 1119–1127.

DOI: https://doi.org/10.1042/BST20170504

Published: 21 September 2018

View article titled, The creatine kinase system as a therapeutic target for myocardial ischaemia–reperfusion injury

Articles

Emerging role of extracellular vesicles in mediating cancer cachexia

Sai V. Chitti, Pamali Fonseka, Suresh Mathivanan

Biochem Soc Trans (2018) 46 (5): 1129–1136.

DOI: https://doi.org/10.1042/BST20180213

Published: 21 September 2018

View article titled, Emerging role of extracellular vesicles in mediating cancer cachexia

Articles

Communicating with the dead: lipids, lipid mediators and extracellular vesicles

Andrew Devitt, Helen R. Griffiths, Ivana Milic

Biochem Soc Trans (2018) 46 (3): 631–639.

DOI: https://doi.org/10.1042/BST20160477

Published: 09 May 2018

View article titled, Communicating with the dead: lipids, lipid mediators and extracellular vesicles

Articles

Subverting the mechanisms of cell death: flavivirus manipulation of host cell responses to infection

Elisa Vicenzi, Isabel Pagani, Silvia Ghezzi, Sarah L. Taylor, Timothy R. Rudd, Marcelo A. Lima, Mark A. Skidmore, Edwin A. Yates

Biochem Soc Trans (2018) 46 (3): 609–617.

DOI: https://doi.org/10.1042/BST20170399

Published: 20 April 2018

View article titled, Subverting the mechanisms of cell death: flavivirus manipulation of host cell responses to infection

Articles

The mechanistic target of rapamycin (mTOR) and the silent mating-type information regulation 2 homolog 1 (SIRT1): oversight for neurodegenerative disorders

Kenneth Maiese

Biochem Soc Trans (2018) 46 (2): 351–360.

DOI: https://doi.org/10.1042/BST20170121

Published: 09 March 2018

View article titled, The mechanistic target of rapamycin (mTOR) and the silent mating-type information regulation 2 homolog 1 (SIRT1): oversight for neurodegenerative disorders

Articles

Lysosomal membrane permeabilization as a cell death mechanism in cancer cells

Ana Serrano-Puebla, Patricia Boya

Biochem Soc Trans (2018) 46 (2): 207–215.

DOI: https://doi.org/10.1042/BST20170130

Published: 22 February 2018

View article titled, Lysosomal membrane permeabilization as a cell death mechanism in cancer cells

Articles

Biochemical targets of drugs mitigating oxidative stress via redox-independent mechanisms

Bernd Gesslbauer, Valery Bochkov

Biochem Soc Trans (2017) 45 (6): 1225–1252.

DOI: https://doi.org/10.1042/BST20160473

Published: 03 November 2017

View article titled, Biochemical targets of drugs mitigating oxidative stress via redox-independent mechanisms

Articles

Oxidative stress and endoplasmic reticulum (ER) stress in the development of neonatal hypoxic–ischaemic brain injury

Claire Thornton, Ana A. Baburamani, Anton Kichev, Henrik Hagberg

Biochem Soc Trans (2017) 45 (5): 1067–1076.

DOI: https://doi.org/10.1042/BST20170017

Published: 22 September 2017

View article titled, Oxidative stress and endoplasmic reticulum (ER) stress in the development of neonatal hypoxic–ischaemic brain injury

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