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Clusters of apoptotic signaling molecule-enriched rafts, CASMERs: membrane platforms for protein assembly in Fas/CD95 signaling and targets in cancer therapy

Faustino Mollinedo, Consuelo Gajate

Biochem Soc Trans (2022) 50 (3): 1105–1118.

DOI: https://doi.org/10.1042/BST20211115

Published: 19 May 2022

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Articles

MMP-7 marks severe pancreatic cancer and alters tumor cell signaling by proteolytic release of ectodomains

Steven R. Van Doren

Biochem Soc Trans (2022) 50 (2): 839–851.

DOI: https://doi.org/10.1042/BST20210640

Published: 28 March 2022

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Articles

Linear ubiquitination in immune and neurodegenerative diseases, and beyond

Fuminori Tokunaga, Fumiyo Ikeda

Biochem Soc Trans (2022) 50 (2): 799–811.

DOI: https://doi.org/10.1042/BST20211078

Published: 28 March 2022

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Articles

PIDD1 in cell cycle control, sterile inflammation and cell death

Elias S. Weiler, Tamas G. Szabo, Irmina Garcia-Carpio, Andreas Villunger

Biochem Soc Trans (2022) 50 (2): 813–824.

DOI: https://doi.org/10.1042/BST20211186

Published: 28 March 2022

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Articles

Therapeutic targeting of mitophagy in Parkinson's disease

Shashank Masaldan, Sylvie Callegari, Grant Dewson

Biochem Soc Trans (2022) 50 (2): 783–797.

DOI: https://doi.org/10.1042/BST20211107

Published: 21 March 2022

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Articles

Role of macrophage extracellular traps in innate immunity and inflammatory disease

Kristian H. Rasmussen, Clare L. Hawkins

Biochem Soc Trans (2022) 50 (1): 21–32.

DOI: https://doi.org/10.1042/BST20210962

Published: 22 February 2022

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Articles

Rare catastrophes and evolutionary legacies: human germline gene variants in MLKL and the necroptosis signalling pathway

Sarah E. Garnish, Joanne M. Hildebrand

Biochem Soc Trans (2022) 50 (1): 529–539.

DOI: https://doi.org/10.1042/BST20210517

Published: 15 February 2022

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Articles

A proteomic perspective on TNF-mediated signalling and cell death

Maria C. Tanzer

Biochem Soc Trans (2022) 50 (1): 13–20.

DOI: https://doi.org/10.1042/BST20211114

Published: 15 February 2022

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Articles

Cardiac regeneration following myocardial infarction: the need for regeneration and a review of cardiac stromal cell populations used for transplantation

Rita Alonaizan, Carolyn Carr

Biochem Soc Trans (2022) 50 (1): 269–281.

DOI: https://doi.org/10.1042/BST20210231

Published: 07 February 2022

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Articles

Identifying new molecular players in extracellular proteostasis

Sandeep Satapathy, Mark R. Wilson

Biochem Soc Trans (2022) 50 (1): 321–334.

DOI: https://doi.org/10.1042/BST20210369

Published: 23 December 2021

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Articles

The role of caspases as executioners of apoptosis

Sharad Kumar, Loretta Dorstyn, Yoon Lim

Biochem Soc Trans (2022) 50 (1): 33–45.

DOI: https://doi.org/10.1042/BST20210751

Published: 23 December 2021

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Articles

VDAC2 and the BCL-2 family of proteins

Zheng Yuan, Grant Dewson, Peter E. Czabotar, Richard W. Birkinshaw

Biochem Soc Trans (2021) 49 (6): 2787–2795.

DOI: https://doi.org/10.1042/BST20210753

Published: 16 December 2021

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Articles

Molecular and structural aspects of gasdermin family pores and insights into gasdermin-elicited programmed cell death

Ayesha Zahid, Hazrat Ismail, Tengchuan Jin

Biochem Soc Trans (2021) 49 (6): 2697–2710.

DOI: https://doi.org/10.1042/BST20210672

Published: 23 November 2021

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Articles

Targeting the BCL-2-regulated apoptotic pathway for the treatment of solid cancers

W. Douglas Fairlie, Erinna F. Lee

Biochem Soc Trans (2021) 49 (5): 2397–2410.

DOI: https://doi.org/10.1042/BST20210750

Published: 28 September 2021

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Articles

Discovery, development and application of drugs targeting BCL-2 pro-survival proteins in cancer

Erinna F. Lee, W. Douglas Fairlie

Biochem Soc Trans (2021) 49 (5): 2381–2395.

DOI: https://doi.org/10.1042/BST20210749

Published: 13 September 2021

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Articles

LRRK2 along the Golgi and lysosome connection: a jamming situation

Giovanni Piccoli, Mattia Volta

Biochem Soc Trans (2021) 49 (5): 2063–2072.

DOI: https://doi.org/10.1042/BST20201146

Published: 08 September 2021

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Articles

Musculoskeletal complications associated with pathological iron toxicity and its molecular mechanisms

Márcio Simão, M. Leonor Cancela

Biochem Soc Trans (2021) 49 (2): 747–759.

DOI: https://doi.org/10.1042/BST20200672

Published: 30 April 2021

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Articles

Phagocytic clearance of apoptotic, necrotic, necroptotic and pyroptotic cells

Georgia K. Atkin-Smith

Biochem Soc Trans (2021) 49 (2): 793–804.

DOI: https://doi.org/10.1042/BST20200696

Published: 12 April 2021

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Articles

Mechanisms of mitochondrial cell death

Shashank Dadsena, Cristiana Zollo, Ana J. García-Sáez

Biochem Soc Trans (2021) 49 (2): 663–674.

DOI: https://doi.org/10.1042/BST20200522

Published: 11 March 2021

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Articles

Mitochondrial DNA in innate immune responses against infectious diseases

Palamou Das, Oishee Chakrabarti

Biochem Soc Trans (2020) 48 (6): 2823–2838.

DOI: https://doi.org/10.1042/BST20200687

Published: 06 November 2020

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Articles

Emerging roles of lamins and DNA damage repair mechanisms in ovarian cancer

Duhita Sengupta, Asima Mukhopadhyay, Kaushik Sengupta

Biochem Soc Trans (2020) 48 (5): 2317–2333.

DOI: https://doi.org/10.1042/BST20200713

Published: 21 October 2020

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Articles

Emerging aspects in the regulation of ferroptosis

Helene Nehring, Svenja Meierjohann, Jose Pedro Friedmann Angeli

Biochem Soc Trans (2020) 48 (5): 2253–2259.

DOI: https://doi.org/10.1042/BST20200523

Published: 14 October 2020

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Articles

Splitting up to heal: mitochondrial shape regulates signaling for focal membrane repair

Adam Horn, Jyoti K. Jaiswal

Biochem Soc Trans (2020) 48 (5): 1995–2002.

DOI: https://doi.org/10.1042/BST20200120

Published: 28 September 2020

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Articles

Unleashing the therapeutic potential of apoptotic bodies

Thanh Kha Phan, Dilara Ceyda Ozkocak, Ivan Ka Ho Poon

Biochem Soc Trans (2020) 48 (5): 2079–2088.

DOI: https://doi.org/10.1042/BST20200225

Published: 01 September 2020

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Articles

Hydrogen peroxide reactivity and specificity in thiol-based cell signalling

Christine C. Winterbourn

Biochem Soc Trans (2020) 48 (3): 745–754.

DOI: https://doi.org/10.1042/BST20190049

Published: 15 May 2020

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Articles

Cytotoxicity of snake venom enzymatic toxins: phospholipase A2 and l-amino acid oxidase

Jia Jin Hiu, Michelle Khai Khun Yap

Biochem Soc Trans (2020) 48 (2): 719–731.

DOI: https://doi.org/10.1042/BST20200110

Published: 08 April 2020

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Articles

The double-edged role of neutrophil extracellular traps in inflammation

Maximilien Euler, Markus H. Hoffmann

Biochem Soc Trans (2019) 47 (6): 1921–1930.

DOI: https://doi.org/10.1042/BST20190629

Published: 22 November 2019

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Articles

Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes

Mark A. Watson, Hoi-Shan Wong, Martin D. Brand

Biochem Soc Trans (2019) 47 (5): 1461–1469.

DOI: https://doi.org/10.1042/BST20190305

Published: 10 September 2019

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Articles

Structural snapshots of RAF kinase interactions

Soheila Rezaei Adariani, Marcel Buchholzer, Mohammad Akbarzadeh, Saeideh Nakhaei-Rad, Radovan Dvorsky, Mohammad Reza Ahmadian

Biochem Soc Trans (2018) 46 (6): 1393–1406.

DOI: https://doi.org/10.1042/BST20170528

Published: 31 October 2018

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Includes: Supplementary data

Articles

New perspectives on IL-33 and IL-1 family cytokines as innate environmental sensors

Ian C. Scott, D. Gareth Rees, E. Suzanne Cohen

Biochem Soc Trans (2018) 46 (5): 1345–1353.

DOI: https://doi.org/10.1042/BST20170567

Published: 09 October 2018

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Articles

The creatine kinase system as a therapeutic target for myocardial ischaemia–reperfusion injury

Fang Cao, Sevasti Zervou, Craig A. Lygate

Biochem Soc Trans (2018) 46 (5): 1119–1127.

DOI: https://doi.org/10.1042/BST20170504

Published: 21 September 2018

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Articles

Emerging role of extracellular vesicles in mediating cancer cachexia

Sai V. Chitti, Pamali Fonseka, Suresh Mathivanan

Biochem Soc Trans (2018) 46 (5): 1129–1136.

DOI: https://doi.org/10.1042/BST20180213

Published: 21 September 2018

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Articles

Communicating with the dead: lipids, lipid mediators and extracellular vesicles

Andrew Devitt, Helen R. Griffiths, Ivana Milic

Biochem Soc Trans (2018) 46 (3): 631–639.

DOI: https://doi.org/10.1042/BST20160477

Published: 09 May 2018

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Articles

Subverting the mechanisms of cell death: flavivirus manipulation of host cell responses to infection

Elisa Vicenzi, Isabel Pagani, Silvia Ghezzi, Sarah L. Taylor, Timothy R. Rudd, Marcelo A. Lima, Mark A. Skidmore, Edwin A. Yates

Biochem Soc Trans (2018) 46 (3): 609–617.

DOI: https://doi.org/10.1042/BST20170399

Published: 20 April 2018

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Articles

The mechanistic target of rapamycin (mTOR) and the silent mating-type information regulation 2 homolog 1 (SIRT1): oversight for neurodegenerative disorders

Kenneth Maiese

Biochem Soc Trans (2018) 46 (2): 351–360.

DOI: https://doi.org/10.1042/BST20170121

Published: 09 March 2018

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Articles

Lysosomal membrane permeabilization as a cell death mechanism in cancer cells

Ana Serrano-Puebla, Patricia Boya

Biochem Soc Trans (2018) 46 (2): 207–215.

DOI: https://doi.org/10.1042/BST20170130

Published: 22 February 2018

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Articles

Biochemical targets of drugs mitigating oxidative stress via redox-independent mechanisms

Bernd Gesslbauer, Valery Bochkov

Biochem Soc Trans (2017) 45 (6): 1225–1252.

DOI: https://doi.org/10.1042/BST20160473

Published: 03 November 2017

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Articles

Oxidative stress and endoplasmic reticulum (ER) stress in the development of neonatal hypoxic–ischaemic brain injury

Claire Thornton, Ana A. Baburamani, Anton Kichev, Henrik Hagberg

Biochem Soc Trans (2017) 45 (5): 1067–1076.

DOI: https://doi.org/10.1042/BST20170017

Published: 22 September 2017

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Articles

Mechanisms of LRRK2-dependent neurodegeneration: role of enzymatic activity and protein aggregation

Md. Shariful Islam, Darren J. Moore

Biochem Soc Trans (2017) 45 (1): 163–172.

DOI: https://doi.org/10.1042/BST20160264

Published: 15 February 2017

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Articles

Stress-induced O-GlcNAcylation: an adaptive process of injured cells

Marissa R. Martinez, Thiago Braido Dias, Peter S. Natov, Natasha E. Zachara

Biochem Soc Trans (2017) 45 (1): 237–249.

DOI: https://doi.org/10.1042/BST20160153

Published: 15 February 2017

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Articles

Neuronal death signaling pathways triggered by mutant LRRK2

Hardy J. Rideout

Biochem Soc Trans (2017) 45 (1): 123–129.

DOI: https://doi.org/10.1042/BST20160256

Published: 15 February 2017

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Articles

The multiple assemblies of VDAC: from conformational heterogeneity to β-aggregation and amyloid formation

Alexandre Boulbrima, Davina Temple, Georgios Psakis

Biochem Soc Trans (2016) 44 (5): 1531–1540.

DOI: https://doi.org/10.1042/BST20160114

Published: 19 October 2016

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