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Articles

The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer

Samuel J. Rodgers, Christina A. Mitchell, Lisa M. Ooms
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (4): 1459–1472.
https://doi.org/10.1042/BST20220866
Published: 20 July 2023
View article titled, The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer
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Articles

Contributions of coxsackievirus adenovirus receptor to tumorigenesis

Claudia Owczarek, Yassmin Elmasry, Maddy Parsons
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1143–1155.
https://doi.org/10.1042/BST20221203
Published: 12 June 2023
View article titled, Contributions of coxsackievirus adenovirus receptor to tumorigenesis
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Articles

Mechanisms of epithelial growth and development in the zebrafish intestine

Reegan J. Willms, Edan Foley
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1213–1224.
https://doi.org/10.1042/BST20221375
Published: 09 June 2023
View article titled, Mechanisms of epithelial growth and development in the zebrafish intestine
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Articles

The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis

Fabian Gude, Jurij Froese, Georg Steffes, Kay Grobe
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 983–993.
https://doi.org/10.1042/BST20220719
Published: 24 May 2023
View article titled, The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis
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Articles

The emerging theme of 3′UTR mRNA isoform regulation in reprogramming of cell metabolism

Qiang Zhang, Bin Tian
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1111–1119.
https://doi.org/10.1042/BST20221128
Published: 12 May 2023
View article titled, The emerging theme of 3′UTR mRNA isoform regulation in reprogramming of cell metabolism
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Articles

The assembly of the MCM2–7 hetero-hexamer and its significance in DNA replication

Yuki Hatoyama, Masato T. Kanemaki
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1289–1295.
https://doi.org/10.1042/BST20221465
Published: 05 May 2023
View article titled, The assembly of the MCM2–7 hetero-hexamer and its significance in DNA replication
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Articles

The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation

Shang Liang, Rajaei Almohammed, Victoria H. Cowling
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1131–1141.
https://doi.org/10.1042/BST20221154
Published: 05 May 2023
View article titled, The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation
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Includes: Supplementary data
Articles

The regulation of meiotic crossover distribution: a coarse solution to a century-old mystery?

Chloe Girard, David Zwicker, Raphael Mercier
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1179–1190.
https://doi.org/10.1042/BST20221329
Published: 05 May 2023
View article titled, The regulation of meiotic crossover distribution: a coarse solution to a century-old mystery?
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Includes: Multimedia, Supplementary data
Articles

The molecular mechanisms of human separase regulation

Jun Yu, David O. Morgan, Andreas Boland
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (3): 1225–1233.
https://doi.org/10.1042/BST20221400
Published: 04 May 2023
View article titled, The molecular mechanisms of human separase regulation
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Articles

Regulation of mTORC1 by the Rag GTPases

Tshering D. Lama-Sherpa, Mi-Hyeon Jeong, Jenna L. Jewell
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 655–664.
https://doi.org/10.1042/BST20210038
Published: 16 March 2023
View article titled, Regulation of mTORC1 by the Rag GTPases
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Articles

Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling

Tahir Muhammad, Jian Li
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 501–512.
https://doi.org/10.1042/BST20220616
Published: 09 March 2023
View article titled, Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling
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Articles

Targeting NRF2 to promote epithelial repair

Paul Hiebert, Sabine Werner
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 101–111.
https://doi.org/10.1042/BST20220228
Published: 10 February 2023
View article titled, Targeting NRF2 to promote epithelial repair
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Articles

Mechanisms of germ cell survival and plasticity in Caenorhabditis elegans

Wei Cao, Roger Pocock
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1517–1526.
https://doi.org/10.1042/BST20220878
Published: 05 October 2022
View article titled, Mechanisms of germ cell survival and plasticity in Caenorhabditis elegans
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Articles

Processing DNA lesions during mitosis to prevent genomic instability

Anastasia Audrey, Lauren de Haan, Marcel A.T.M. van Vugt, H. Rudolf de Boer
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (4): 1105–1118.
https://doi.org/10.1042/BST20220049
Published: 30 August 2022
View article titled, Processing DNA lesions during mitosis to prevent genomic instability
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Articles

Tumour invasion and dissemination

Ryan Lusby, Philip Dunne, Vijay K. Tiwari
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1245–1257.
https://doi.org/10.1042/BST20220452
Published: 17 June 2022
View article titled, Tumour invasion and dissemination
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Articles

CDK activity sensors: genetically encoded ratiometric biosensors for live analysis of the cell cycle

Michael A. Q. Martinez, David Q. Matus
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1081–1090.
https://doi.org/10.1042/BST20211131
Published: 08 June 2022
View article titled, CDK activity sensors: genetically encoded ratiometric biosensors for live analysis of the cell cycle
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Articles

Mitotic drive in asymmetric epigenetic inheritance

Rajesh Ranjan, Xin Chen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 675–688.
https://doi.org/10.1042/BST20200267
Published: 19 April 2022
View article titled, Mitotic drive in asymmetric epigenetic inheritance
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Articles

Functional diversity in the RAS subfamily of small GTPases

Gabriela Bernal Astrain, Maya Nikolova, Matthew J. Smith
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 921–933.
https://doi.org/10.1042/BST20211166
Published: 31 March 2022
View article titled, Functional diversity in the RAS subfamily of small GTPases
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Articles

PIDD1 in cell cycle control, sterile inflammation and cell death

In Collection
Cell death and survival
Elias S. Weiler, Tamas G. Szabo, Irmina Garcia-Carpio, Andreas Villunger
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 813–824.
https://doi.org/10.1042/BST20211186
Published: 28 March 2022
View article titled, PIDD1 in cell cycle control, sterile inflammation and cell death
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Articles

The intricate roles of RCC1 in normal cells and cancer cells

Li Jing, Hang Fai Kwok
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 83–93.
https://doi.org/10.1042/BST20210861
Published: 22 February 2022
View article titled, The intricate roles of RCC1 in normal cells and cancer cells
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Articles

Bioimaging approaches for quantification of individual cell behavior during cell fate decisions

Karine R. Begnini, Luiza C. Pereira, Juliano L. Faccioni, Guido Lenz, Eduardo C. Filippi-Chiela
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 513–527.
https://doi.org/10.1042/BST20210534
Published: 15 February 2022
View article titled, Bioimaging approaches for quantification of individual cell behavior during cell fate decisions
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Articles

Chromosome clustering in mitosis by the nuclear protein Ki-67

Konstantinos Stamatiou, Paola Vagnarelli
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2767–2776.
https://doi.org/10.1042/BST20210717
Published: 16 November 2021
View article titled, Chromosome clustering in mitosis by the nuclear protein Ki-67
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Articles

Identifying key regulators of the intestinal stem cell niche

Carrie A. Duckworth
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2163–2176.
https://doi.org/10.1042/BST20210223
Published: 19 October 2021
View article titled, Identifying key regulators of the intestinal stem cell niche
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Articles

Targeting the BCL-2-regulated apoptotic pathway for the treatment of solid cancers

In Collection
Cell death and survival
W. Douglas Fairlie, Erinna F. Lee
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2397–2410.
https://doi.org/10.1042/BST20210750
Published: 28 September 2021
View article titled, Targeting the BCL-2-regulated apoptotic pathway for the treatment of solid cancers
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Articles

Efficiency and equity in origin licensing to ensure complete DNA replication

Liu Mei, Jeanette Gowen Cook
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2133–2141.
https://doi.org/10.1042/BST20210161
Published: 21 September 2021
View article titled, Efficiency and equity in origin licensing to ensure complete DNA replication
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Articles

Mechanisms of vascular smooth muscle cell investment and phenotypic diversification in vascular diseases

Matthew D. Worssam, Helle F. Jørgensen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2101–2111.
https://doi.org/10.1042/BST20210138
Published: 08 September 2021
View article titled, Mechanisms of vascular smooth muscle cell investment and phenotypic diversification in vascular diseases
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Articles

Progress and challenges in understanding the regulation and function of p53 dynamics

Zhilin Yang, Ryan L. Hanson, Eric Batchelor
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2123–2131.
https://doi.org/10.1042/BST20210148
Published: 08 September 2021
View article titled, Progress and challenges in understanding the regulation and function of p53 dynamics
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Articles

How neural stem cells contribute to neocortex development

Lei Xing, Michaela Wilsch-Bräuninger, Wieland B. Huttner
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 1997–2006.
https://doi.org/10.1042/BST20200923
Published: 16 August 2021
View article titled, How neural stem cells contribute to neocortex development
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Articles

Cellular feedback dynamics and multilevel regulation driven by the hippo pathway

Jiwon Park, Carsten Gram Hansen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1515–1527.
https://doi.org/10.1042/BST20200253
Published: 10 August 2021
View article titled, Cellular feedback dynamics and multilevel regulation driven by the hippo pathway
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Articles

Evolution and diversification of the nuclear pore complex

Alexandr A. Makarov, Norma E. Padilla-Mejia, Mark C. Field
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1601–1619.
https://doi.org/10.1042/BST20200570
Published: 20 July 2021
View article titled, Evolution and diversification of the nuclear pore complex
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Articles

Transcriptional control of ribosome biogenesis in yeast: links to growth and stress signals

David Shore, Sevil Zencir, Benjamin Albert
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1589–1599.
https://doi.org/10.1042/BST20201136
Published: 09 July 2021
View article titled, Transcriptional control of ribosome biogenesis in yeast: links to growth and stress signals
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Articles

Roles for growth factors and mutations in metastatic dissemination

Nishanth Belugali Nataraj, Ilaria Marrocco, Yosef Yarden
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (3): 1409–1423.
https://doi.org/10.1042/BST20210048
Published: 08 June 2021
View article titled, Roles for growth factors and mutations in metastatic dissemination
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Articles

Links between the unfolded protein response and the DNA damage response in hypoxia: a systematic review

Hannah Bolland, Tiffany S. Ma, Syafiq Ramlee, Kristijan Ramadan, Ester M. Hammond
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (3): 1251–1263.
https://doi.org/10.1042/BST20200861
Published: 18 May 2021
View article titled, Links between the unfolded protein response and the DNA damage response in hypoxia: a systematic review
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Includes: Supplementary data
Articles

SAPs as a new model to probe the pathway of centriole and centrosome assembly

Alan Wainman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (3): 1233–1240.
https://doi.org/10.1042/BST20200833
Published: 07 May 2021
View article titled, SAPs as a new model to probe the pathway of centriole and centrosome assembly
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Articles

Engineered cell-laden alginate microparticles for 3D culture

Bumseok Namgung, Kalpana Ravi, Pooja Prathyushaa Vikraman, Shiladitya Sengupta, Hae Lin Jang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 761–773.
https://doi.org/10.1042/BST20200673
Published: 16 April 2021
View article titled, Engineered cell-laden alginate microparticles for 3D culture
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Articles

Primary cilia and the DNA damage response: linking a cellular antenna and nuclear signals

Ciaran G. Morrison
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 829–841.
https://doi.org/10.1042/BST20200751
Published: 12 April 2021
View article titled, Primary cilia and the DNA damage response: linking a cellular antenna and nuclear signals
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Articles

The regulation of the DNA damage response at telomeres: focus on kinases

Michela Galli, Chiara Frigerio, Maria Pia Longhese, Michela Clerici
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (2): 933–943.
https://doi.org/10.1042/BST20200856
Published: 26 March 2021
View article titled, The regulation of the DNA damage response at telomeres: focus on kinases
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Articles

CHCHD4 (MIA40) and the mitochondrial disulfide relay system

Hasan Al-Habib, Margaret Ashcroft
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 17–27.
https://doi.org/10.1042/BST20190232
Published: 18 February 2021
View article titled, CHCHD4 (MIA40) and the mitochondrial disulfide relay system
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Articles

Promotion of cancer cell stemness by Ras

Rohan Chippalkatti, Daniel Abankwa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 467–476.
https://doi.org/10.1042/BST20200964
Published: 05 February 2021
View article titled, Promotion of cancer cell stemness by Ras
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Articles

The ERK mitogen-activated protein kinase signaling network: the final frontier in RAS signal transduction

Jennifer E. Klomp, Jeff A. Klomp, Channing J. Der
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 253–267.
https://doi.org/10.1042/BST20200507
Published: 05 February 2021
View article titled, The ERK mitogen-activated protein kinase signaling network: the final frontier in RAS signal transduction
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Articles

The structure and function of protein kinase C-related kinases (PRKs)

Georgios Sophocleous, Darerca Owen, Helen R. Mott
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 217–235.
https://doi.org/10.1042/BST20200466
Published: 01 February 2021
View article titled, The structure and function of protein kinase C-related kinases (PRKs)
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Articles

Aneuploidy in human eggs: contributions of the meiotic spindle

In Collection
Awards
Christopher Thomas, Tommaso Cavazza, Melina Schuh
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 107–118.
https://doi.org/10.1042/BST20200043
Published: 15 January 2021
View article titled, Aneuploidy in human eggs: contributions of the meiotic spindle
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Articles

Inhibition of RAF dimers: it takes two to tango

Frazer A. Cook, Simon J. Cook
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (1): 237–251.
https://doi.org/10.1042/BST20200485
Published: 24 December 2020
View article titled, Inhibition of RAF dimers: it takes two to tango
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Articles

Plant cell divisions: variations from the shortest symmetric path

Léo Serra, Sarah Robinson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (6): 2743–2752.
https://doi.org/10.1042/BST20200529
Published: 18 December 2020
View article titled, Plant cell divisions: variations from the shortest symmetric path
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Articles

Post-transcriptional control of mitochondrial protein composition in changing environmental conditions

Tatsuhisa Tsuboi, Jordan Leff, Brian M. Zid
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (6): 2565–2578.
https://doi.org/10.1042/BST20200250
Published: 27 November 2020
View article titled, Post-transcriptional control of mitochondrial protein composition in changing environmental conditions
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Articles

Spatio-temporal regulation of gene expression defines subpopulations of epidermal stem cells

Maneesha Aruketty, Svitlana Kurinna
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (6): 2839–2850.
https://doi.org/10.1042/BST20200740
Published: 10 November 2020
View article titled, Spatio-temporal regulation of gene expression defines subpopulations of epidermal stem cells
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Articles

Effects of carboxyl-terminal methylation on holoenzyme function of the PP2A subfamily

Isha Nasa, Arminja N. Kettenbach
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 2015–2027.
https://doi.org/10.1042/BST20200177
Published: 14 October 2020
View article titled, Effects of carboxyl-terminal methylation on holoenzyme function of the PP2A subfamily
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Articles

Human 2-oxoglutarate-dependent oxygenases: nutrient sensors, stress responders, and disease mediators

Sally C. Fletcher, Mathew L. Coleman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 1843–1858.
https://doi.org/10.1042/BST20190333
Published: 28 September 2020
View article titled, Human 2-oxoglutarate-dependent oxygenases: nutrient sensors, stress responders, and disease mediators
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Articles

Smc5/6, an atypical SMC complex with two RING-type subunits

Roger Solé-Soler, Jordi Torres-Rosell
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 2159–2171.
https://doi.org/10.1042/BST20200389
Published: 23 September 2020
View article titled, Smc5/6, an atypical SMC complex with two RING-type subunits
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Articles

Review on material parameters to enhance bone cell function in vitro and in vivo

Eric Madsen, Merjem Mededovic, David H. Kohn
Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (5): 2039–2050.
https://doi.org/10.1042/BST20200210
Published: 17 September 2020
View article titled, Review on material parameters to enhance bone cell function in vitro and in vivo
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