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Articles

The Nrd1–Nab3–Sen1 transcription termination complex from a structural perspective

Belén Chaves-Arquero, José Manuel Pérez-Cañadillas
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) BST20221418.
DOI: https://doi.org/10.1042/BST20221418
Published: 24 May 2023
View article titled, The Nrd1–Nab3–Sen1 transcription termination complex from a structural perspective
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Articles

The regulation of meiotic crossover distribution: a coarse solution to a century-old mystery?

Chloe Girard, David Zwicker, Raphael Mercier
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) BST20221329.
DOI: https://doi.org/10.1042/BST20221329
Published: 05 May 2023
View article titled, The regulation of meiotic crossover distribution: a coarse solution to a century-old mystery?
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Includes: Multimedia, Supplementary data
Articles

Sculpting with stiffness: rigidity as a regulator of morphogenesis

Adam Shellard, Roberto Mayor
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) BST20220826.
DOI: https://doi.org/10.1042/BST20220826
Published: 28 April 2023
View article titled, Sculpting with stiffness: rigidity as a regulator of morphogenesis
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Articles

Improving the hole picture: towards a consensus on the mechanism of nuclear transport

David Cowburn, Michael Rout
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 871–886.
DOI: https://doi.org/10.1042/BST20220494
Published: 26 April 2023
View article titled, Improving the hole picture: towards a consensus on the mechanism of nuclear transport
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Articles

The building blocks of caveolae revealed: caveolins finally take center stage

Anne K. Kenworthy
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 855–869.
DOI: https://doi.org/10.1042/BST20221298
Published: 21 April 2023
View article titled, The building blocks of caveolae revealed: caveolins finally take center stage
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Articles

What voltage-sensing phosphatases can reveal about the mechanisms of ion channel regulation by phosphoinositides

Yasushi Okamura, Daisuke Yoshioka
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (2): 827–839.
DOI: https://doi.org/10.1042/BST20221065
Published: 13 April 2023
View article titled, What voltage-sensing phosphatases can reveal about the mechanisms of ion channel regulation by phosphoinositides
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Articles

The interactions of amyloid β aggregates with phospholipid membranes and the implications for neurodegeneration

Rima Budvytyte, Gintaras Valincius
Journal: Biochemical Society Transactions
Biochem Soc Trans (2023) 51 (1): 147–159.
DOI: https://doi.org/10.1042/BST20220434
Published: 11 January 2023
View article titled, The interactions of amyloid β aggregates with phospholipid membranes and the implications for neurodegeneration
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Articles

The mechanisms of chromogranin B-regulated Cl − homeostasis

Qiu-Xing Jiang, Gaya Yadav
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1659–1672.
DOI: https://doi.org/10.1042/BST20220435
Published: 13 December 2022
View article titled, The mechanisms of chromogranin B-regulated Cl − homeostasis
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Articles

The influence of high-order chromatin state in the regulation of stem cell fate

Xinpeng Chen, Haiyan Lin, Guohong Li
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1809–1822.
DOI: https://doi.org/10.1042/BST20220763
Published: 09 December 2022
View article titled, The influence of high-order chromatin state in the regulation of stem cell fate
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Articles

Deciphering the mechanism and function of Hsp100 unfoldases from protein structure

Grace Lee, Rebecca S. Kim, Sang Bum Lee, Sukyeong Lee, Francis T.F. Tsai
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1725–1736.
DOI: https://doi.org/10.1042/BST20220590
Published: 01 December 2022
View article titled, Deciphering the mechanism and function of Hsp100 unfoldases from protein structure
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Articles

Investigating how intrinsically disordered regions contribute to protein function using HDX-MS

Matthew A.H. Parson, Meredith L. Jenkins, John E. Burke
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1607–1617.
DOI: https://doi.org/10.1042/BST20220206
Published: 01 December 2022
View article titled, Investigating how intrinsically disordered regions contribute to protein function using HDX-MS
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Articles

Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt

Neha Mani, Rie Nygaard, Filippo Mancia
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1763–1772.
DOI: https://doi.org/10.1042/BST20220634
Published: 23 November 2022
View article titled, Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt
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Articles

Cardiotoxicity of pyrethroids: molecular mechanisms and therapeutic options for acute and long-term toxicity

Leisiane P. Marques, Julliane V. Joviano-Santos, Diego S. Souza, A. Santos-Miranda, D. Roman-Campos
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (6): 1737–1751.
DOI: https://doi.org/10.1042/BST20220593
Published: 16 November 2022
View article titled, Cardiotoxicity of pyrethroids: molecular mechanisms and therapeutic options for acute and long-term toxicity
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Articles

The role of UV-DDB in processing 8-oxoguanine during base excision repair

Ashna Nagpal, Sripriya Raja, Bennett Van Houten
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1481–1488.
DOI: https://doi.org/10.1042/BST20220748
Published: 28 October 2022
View article titled, The role of UV-DDB in processing 8-oxoguanine during base excision repair
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Articles

Dynamics of phagocytosis mediated by phosphatidylserine

Daan Vorselen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1281–1291.
DOI: https://doi.org/10.1042/BST20211254
Published: 25 October 2022
View article titled, Dynamics of phagocytosis mediated by phosphatidylserine
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Articles

Characterising ion channel structure and dynamics using fluorescence spectroscopy techniques

Shreyas Bhat, Rikard Blunck
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1427–1445.
DOI: https://doi.org/10.1042/BST20220605
Published: 25 October 2022
View article titled, Characterising ion channel structure and dynamics using fluorescence spectroscopy techniques
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Articles

A comprehensive review of methods to study lncRNA–protein interactions in solution

Maulik D. Badmalia, Higor Sette Pereira, M. Quadir Siddiqui, Trushar R. Patel
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1415–1426.
DOI: https://doi.org/10.1042/BST20220604
Published: 17 October 2022
View article titled, A comprehensive review of methods to study lncRNA–protein interactions in solution
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Articles

Strength in numbers: effect of protein crowding on the shape of cell membranes

Victoria Thusgaard Ruhoff, Guillermo Moreno-Pescador, Weria Pezeshkian, Poul Martin Bendix
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1257–1267.
DOI: https://doi.org/10.1042/BST20210883
Published: 10 October 2022
View article titled, Strength in numbers: effect of protein crowding on the shape of cell membranes
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Articles

How does an organism extract relevant information from transcription factor concentrations?

Marianne Bauer
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1365–1376.
DOI: https://doi.org/10.1042/BST20220333
Published: 16 September 2022
View article titled, How does an organism extract relevant information from transcription factor concentrations?
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Articles

Studying actin-induced cell shape changes using Giant Unilamellar Vesicles and reconstituted actin networks

Rogério Lopes dos Santos, Clément Campillo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1527–1539.
DOI: https://doi.org/10.1042/BST20220900
Published: 16 September 2022
View article titled, Studying actin-induced cell shape changes using Giant Unilamellar Vesicles and reconstituted actin networks
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Articles

Effects of antibiotics on bacterial cell morphology and their physiological origins

Callaghan Cylke, Fangwei Si, Shiladitya Banerjee
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1269–1279.
DOI: https://doi.org/10.1042/BST20210894
Published: 12 September 2022
View article titled, Effects of antibiotics on bacterial cell morphology and their physiological origins
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Articles

Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques

Chung Yu Chan, Youssef Faragalla, Ling-Gang Wu
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (4): 1157–1167.
DOI: https://doi.org/10.1042/BST20210263
Published: 12 August 2022
View article titled, Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques
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Articles

AAA+ proteins: one motor, multiple ways to work

JiaBei Lin, James Shorter, Aaron L. Lucius
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 895–906.
DOI: https://doi.org/10.1042/BST20200350
Published: 31 March 2022
View article titled, AAA+ proteins: one motor, multiple ways to work
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Articles

Understanding immune signaling using advanced imaging techniques

Mario Brameshuber, Enrico Klotzsch, Aleks Ponjavic, Erdinc Sezgin
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 853–866.
DOI: https://doi.org/10.1042/BST20210479
Published: 28 March 2022
View article titled, Understanding immune signaling using advanced imaging techniques
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Articles

A guide into the world of high-resolution 3D imaging: the case of soft X-ray tomography for the life sciences

Chidinma Adanna Okolo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 649–663.
DOI: https://doi.org/10.1042/BST20210886
Published: 08 March 2022
View article titled, A guide into the world of high-resolution 3D imaging: the case of soft X-ray tomography for the life sciences
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Articles

Exploring cryo-electron microscopy with molecular dynamics

John W. Vant, Daipayan Sarkar, Jonathan Nguyen, Alexander T. Baker, Josh V. Vermaas, Abhishek Singharoy
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 569–581.
DOI: https://doi.org/10.1042/BST20210485
Published: 25 February 2022
View article titled, Exploring cryo-electron microscopy with molecular dynamics
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Articles

How lipids affect the energetics of co-translational alpha helical membrane protein folding

Ryan Brady, Nicola J. Harris, Grant A. Pellowe, Samuel Gulaidi Breen, Paula J. Booth
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 555–567.
DOI: https://doi.org/10.1042/BST20201063
Published: 25 February 2022
View article titled, How lipids affect the energetics of co-translational alpha helical membrane protein folding
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Articles

Studying membrane proteins with MicroED

Marc J. Gallenito, Tamir Gonen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 231–239.
DOI: https://doi.org/10.1042/BST20210911
Published: 22 February 2022
View article titled, Studying membrane proteins with MicroED
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Articles

Conformational ensembles of intrinsically disordered proteins and flexible multidomain proteins

F. Emil Thomasen, Kresten Lindorff-Larsen
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 541–554.
DOI: https://doi.org/10.1042/BST20210499
Published: 07 February 2022
View article titled, Conformational ensembles of intrinsically disordered proteins and flexible multidomain proteins
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Articles

Norovirus–glycan interactions — how strong are they really?

Thomas Peters, Robert Creutznacher, Thorben Maass, Alvaro Mallagaray, Patrick Ogrissek, Stefan Taube, Lars Thiede, Charlotte Uetrecht
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (1): 347–359.
DOI: https://doi.org/10.1042/BST20210526
Published: 23 December 2021
View article titled, Norovirus–glycan interactions — how strong are they really?
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Articles

Viscoelastic properties of epithelial cells

Andreas Janshoff
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2687–2695.
DOI: https://doi.org/10.1042/BST20210476
Published: 02 December 2021
View article titled, Viscoelastic properties of epithelial cells
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Articles

Spatiotemporal regulation of store-operated calcium entry in cancer metastasis

Fujian Lu, Yunzhan Li, Shengchen Lin, Heping Cheng, Shengyu Yang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2581–2589.
DOI: https://doi.org/10.1042/BST20210307
Published: 02 December 2021
View article titled, Spatiotemporal regulation of store-operated calcium entry in cancer metastasis
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Articles

MsbA: an ABC transporter paradigm

Christian Bonifer, Clemens Glaubitz
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2917–2927.
DOI: https://doi.org/10.1042/BST20211030
Published: 25 November 2021
View article titled, MsbA: an ABC transporter paradigm
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Articles

Structural and functional approaches to studying cAMP regulation of HCN channels

Andrea Saponaro, Gerhard Thiel, Anna Moroni
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2573–2579.
DOI: https://doi.org/10.1042/BST20210290
Published: 23 November 2021
View article titled, Structural and functional approaches to studying cAMP regulation of HCN channels
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Articles

Applications of Cryo-EM in small molecule and biologics drug design

Joshua A. Lees, Joao M. Dias, Seungil Han
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2627–2638.
DOI: https://doi.org/10.1042/BST20210444
Published: 23 November 2021
View article titled, Applications of Cryo-EM in small molecule and biologics drug design
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Articles

Pluripotency transcription factors at the focus: the phase separation paradigm in stem cells

Camila Oses, Martin Stortz, Paula Verneri, Alejandra Guberman, Valeria Levi
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2871–2878.
DOI: https://doi.org/10.1042/BST20210856
Published: 23 November 2021
View article titled, Pluripotency transcription factors at the focus: the phase separation paradigm in stem cells
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Articles

Computational methods to study enveloped viral entry

Alzbeta Tuerkova, Peter M. Kasson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2527–2537.
DOI: https://doi.org/10.1042/BST20210190
Published: 16 November 2021
View article titled, Computational methods to study enveloped viral entry
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Includes: Supplementary data
Articles

Challenges and approaches to studying pore-forming proteins

Joshua T. Benton, Charles Bayly-Jones
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2749–2765.
DOI: https://doi.org/10.1042/BST20210706
Published: 08 November 2021
View article titled, Challenges and approaches to studying pore-forming proteins
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Articles

Structural insights into the interactions of Polycomb Repressive Complex 2 with chromatin

Akhil Gargey Iragavarapu, Liqi Yao, Vignesh Kasinath
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (6): 2639–2653.
DOI: https://doi.org/10.1042/BST20210450
Published: 08 November 2021
View article titled, Structural insights into the interactions of Polycomb Repressive Complex 2 with chromatin
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Articles

Conquer by cryo-EM without physically dividing

Gabriel C. Lander, Robert M. Glaeser
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2287–2298.
DOI: https://doi.org/10.1042/BST20210360
Published: 28 October 2021
View article titled, Conquer by cryo-EM without physically dividing
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Articles

Ca 2+ -dependent modulation of voltage-gated myocyte sodium channels

Samantha C. Salvage, Zaki F. Habib, Hugh R. Matthews, Antony P. Jackson, Christopher L.-H. Huang
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 1941–1961.
DOI: https://doi.org/10.1042/BST20200604
Published: 13 October 2021
View article titled, Ca 2+ -dependent modulation of voltage-gated myocyte sodium channels
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Articles

Biophysical characterisation of SMALPs

Stephanie A. Nestorow, Tim R. Dafforn, Verna Frasca
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2037–2050.
DOI: https://doi.org/10.1042/BST20201088
Published: 13 October 2021
View article titled, Biophysical characterisation of SMALPs
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Articles

Thermodynamic and structural basis of temperature-dependent gating in TRP channels

Ignacio Diaz-Franulic, Christian Verdugo, Felipe Gonzalez, Fernando Gonzalez-Nilo, Ramon Latorre
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2211–2219.
DOI: https://doi.org/10.1042/BST20210301
Published: 08 October 2021
View article titled, Thermodynamic and structural basis of temperature-dependent gating in TRP channels
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Articles

Structure determination of GPCRs: cryo-EM compared with X-ray crystallography

Javier García-Nafría, Christopher G. Tate
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2345–2355.
DOI: https://doi.org/10.1042/BST20210431
Published: 28 September 2021
View article titled, Structure determination of GPCRs: cryo-EM compared with X-ray crystallography
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Articles

Correlative nanophotonic approaches to enlighten the nanoscale dynamics of living cell membranes

Pamina M. Winkler, María F. García-Parajo
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (5): 2357–2369.
DOI: https://doi.org/10.1042/BST20210457
Published: 08 September 2021
View article titled, Correlative nanophotonic approaches to enlighten the nanoscale dynamics of living cell membranes
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Articles

Lipid–protein interactions in virus assembly and budding from the host cell plasma membrane

Balindile B. Motsa, Robert V. Stahelin
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1633–1641.
DOI: https://doi.org/10.1042/BST20200854
Published: 25 August 2021
View article titled, Lipid–protein interactions in virus assembly and budding from the host cell plasma membrane
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Articles

The influence of lipid digestion on the fate of orally administered drug delivery vehicles

Ben J. Boyd, Andrew J. Clulow
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1749–1761.
DOI: https://doi.org/10.1042/BST20210168
Published: 25 August 2021
View article titled, The influence of lipid digestion on the fate of orally administered drug delivery vehicles
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Articles

Methods for the solubilisation of membrane proteins: the micelle-aneous world of membrane protein solubilisation

Giedre Ratkeviciute, Benjamin F. Cooper, Timothy J. Knowles
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1763–1777.
DOI: https://doi.org/10.1042/BST20210181
Published: 20 August 2021
View article titled, Methods for the solubilisation of membrane proteins: the micelle-aneous world of membrane protein solubilisation
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Articles

Mechanisms of catalytic RNA molecules

Dulce Alonso, Alfonso Mondragón
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1529–1535.
DOI: https://doi.org/10.1042/BST20200465
Published: 20 August 2021
View article titled, Mechanisms of catalytic RNA molecules
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Articles

Solid state NMR of membrane proteins: methods and applications

Vivien Yeh, Boyan B. Bonev
Journal: Biochemical Society Transactions
Biochem Soc Trans (2021) 49 (4): 1505–1513.
DOI: https://doi.org/10.1042/BST20200070
Published: 16 August 2021
View article titled, Solid state NMR of membrane proteins: methods and applications
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