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Articles

New insights into the mechanochemical coupling mechanism of kinesin–microtubule complexes from their high-resolution structures

Matthieu P.M.H. Benoit, Byron Hunter, John S. Allingham, Hernando Sosa

Biochem Soc Trans (2023) 51 (4): 1505–1520.

https://doi.org/10.1042/BST20221238

Published: 10 August 2023

View article titled, New insights into the mechanochemical coupling mechanism of kinesin–microtubule complexes from their high-resolution structures

Includes: Supplementary data

Articles

Maximizing the performance of protein-based fluorescent biosensors

Fu Chai, Dazhou Cheng, Yusuke Nasu, Takuya Terai, Robert E. Campbell

Biochem Soc Trans (2023) 51 (4): 1585–1595.

https://doi.org/10.1042/BST20221413

Published: 11 July 2023

View article titled, Maximizing the performance of protein-based fluorescent biosensors

Articles

How far can omics go in unveiling the mechanisms of floral senescence?

Hilary J. Rogers

Biochem Soc Trans (2023) 51 (4): 1485–1493.

https://doi.org/10.1042/BST20221097

Published: 30 June 2023

View article titled, How far can omics go in unveiling the mechanisms of floral senescence?

Articles

Recent advances in membrane mimetics for membrane protein research

John William Young

Biochem Soc Trans (2023) 51 (3): 1405–1416.

https://doi.org/10.1042/BST20230164

Published: 22 June 2023

View article titled, Recent advances in membrane mimetics for membrane protein research

Articles

Fast-forward on P-type ATPases: recent advances on structure and function

Charlott Stock, Tomáš Heger, Sara Basse Hansen, Sigrid Thirup Larsen, Michael Habeck, Thibaud Dieudonné, Ronja Driller, Poul Nissen

Biochem Soc Trans (2023) 51 (3): 1347–1360.

https://doi.org/10.1042/BST20221543

Published: 02 June 2023

View article titled, Fast-forward on P-type ATPases: recent advances on structure and function

Articles

Improving the hole picture: towards a consensus on the mechanism of nuclear transport

David Cowburn, Michael Rout

Biochem Soc Trans (2023) 51 (2): 871–886.

https://doi.org/10.1042/BST20220494

Published: 26 April 2023

View article titled, Improving the hole picture: towards a consensus on the mechanism of nuclear transport

Articles

Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology

Zhengyuan Huang, Pei F. Lai, Alexander T. H. Cocker, Stuart M. Haslam, Anne Dell, Hugh J. M. Brady, Mark R. Johnson

Biochem Soc Trans (2023) 51 (2): 639–653.

https://doi.org/10.1042/BST20221406

Published: 16 March 2023

View article titled, Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology

Articles

Single-molecule tracking (SMT): a window into live-cell transcription biochemistry

Liza Dahal, Nike Walther, Robert Tjian, Xavier Darzacq, Thomas G.W. Graham

Biochem Soc Trans (2023) 51 (2): 557–569.

https://doi.org/10.1042/BST20221242

Published: 06 March 2023

View article titled, Single-molecule tracking (SMT): a window into live-cell transcription biochemistry

Articles

Towards using 3D cellular cultures to model the activation and diverse functions of macrophages

Sean Cutter, Mark D. Wright, Nicholas P. Reynolds, Katrina Jean Binger

Biochem Soc Trans (2023) 51 (1): 387–401.

https://doi.org/10.1042/BST20221008

Published: 06 February 2023

View article titled, Towards using 3D cellular cultures to model the activation and diverse functions of macrophages

Articles

Eliminating oncogenic RAS: back to the future at the drawing board

Candy Laura Steffen, Pelin Kaya, Elisabeth Schaffner-Reckinger, Daniel Abankwa

Biochem Soc Trans (2023) 51 (1): 447–456.

https://doi.org/10.1042/BST20221343

Published: 23 January 2023

View article titled, Eliminating oncogenic RAS: back to the future at the drawing board

Includes: Supplementary data

Articles

Interactions governing transcriptional activity of nuclear receptors

Sabab Hasan Khan, C. Denise Okafor

Biochem Soc Trans (2022) 50 (6): 1941–1952.

https://doi.org/10.1042/BST20220338

Published: 16 December 2022

View article titled, Interactions governing transcriptional activity of nuclear receptors

Articles

General strategies for using amino acid sequence data to guide biochemical investigation of protein function

Emily N. Kennedy, Clay A. Foster, Sarah A. Barr, Robert B. Bourret

Biochem Soc Trans (2022) 50 (6): 1847–1858.

https://doi.org/10.1042/BST20220849

Published: 23 November 2022

View article titled, General strategies for using amino acid sequence data to guide biochemical investigation of protein function

Articles

Specific isotopic labelling and reverse labelling for protein NMR spectroscopy: using metabolic precursors in sample preparation

Benjamin Rowlinson, Elodie Crublet, Rime Kerfah, Michael J. Plevin

Biochem Soc Trans (2022) 50 (6): 1555–1567.

https://doi.org/10.1042/BST20210586

Published: 16 November 2022

View article titled, Specific isotopic labelling and reverse labelling for protein NMR spectroscopy: using metabolic precursors in sample preparation

Articles

Frankenstein Cas9: engineering improved gene editing systems

Pascal D. Vos, Aleksandra Filipovska, Oliver Rackham

Biochem Soc Trans (2022) 50 (5): 1505–1516.

https://doi.org/10.1042/BST20220873

Published: 28 October 2022

View article titled, Frankenstein Cas9: engineering improved gene editing systems

Articles

Characterising ion channel structure and dynamics using fluorescence spectroscopy techniques

Shreyas Bhat, Rikard Blunck

Biochem Soc Trans (2022) 50 (5): 1427–1445.

https://doi.org/10.1042/BST20220605

Published: 25 October 2022

View article titled, Characterising ion channel structure and dynamics using fluorescence spectroscopy techniques

Articles

A comprehensive review of methods to study lncRNA–protein interactions in solution

Maulik D. Badmalia, Higor Sette Pereira, M. Quadir Siddiqui, Trushar R. Patel

Biochem Soc Trans (2022) 50 (5): 1415–1426.

https://doi.org/10.1042/BST20220604

Published: 17 October 2022

View article titled, A comprehensive review of methods to study lncRNA–protein interactions in solution

Articles

Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques

Chung Yu Chan, Youssef Faragalla, Ling-Gang Wu

Biochem Soc Trans (2022) 50 (4): 1157–1167.

https://doi.org/10.1042/BST20210263

Published: 12 August 2022

View article titled, Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques

Articles

AAA+ proteins: one motor, multiple ways to work

JiaBei Lin, James Shorter, Aaron L. Lucius

Biochem Soc Trans (2022) 50 (2): 895–906.

https://doi.org/10.1042/BST20200350

Published: 31 March 2022

View article titled, AAA+ proteins: one motor, multiple ways to work

Articles

Stop CRYing! Inhibition of cryptochrome function by small proteins

Valdeko Kruusvee, Arendse Maria Toft, Blanche Aguida, Margaret Ahmad, Stephan Wenkel

Biochem Soc Trans (2022) 50 (2): 773–782.

https://doi.org/10.1042/BST20190062

Published: 21 March 2022

View article titled, Stop CRYing! Inhibition of cryptochrome function by small proteins

Articles

A guide into the world of high-resolution 3D imaging: the case of soft X-ray tomography for the life sciences

Chidinma Adanna Okolo

Biochem Soc Trans (2022) 50 (2): 649–663.

https://doi.org/10.1042/BST20210886

Published: 08 March 2022

View article titled, A guide into the world of high-resolution 3D imaging: the case of soft X-ray tomography for the life sciences

Articles

New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease

In Collection

Awards

Valerie B. O'Donnell

Biochem Soc Trans (2022) 50 (1): 1–11.

https://doi.org/10.1042/BST20210579

Published: 28 February 2022

View article titled, New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease

Articles

How lipids affect the energetics of co-translational alpha helical membrane protein folding

Ryan Brady, Nicola J. Harris, Grant A. Pellowe, Samuel Gulaidi Breen, Paula J. Booth

Biochem Soc Trans (2022) 50 (1): 555–567.

https://doi.org/10.1042/BST20201063

Published: 25 February 2022

View article titled, How lipids affect the energetics of co-translational alpha helical membrane protein folding

Articles

Whole-genome methods to define DNA and histone accessibility and long-range interactions in chromatin

Luke T. Marr, Prasoon Jaya, Laxmi N. Mishra, Jeffrey J. Hayes

Biochem Soc Trans (2022) 50 (1): 199–212.

https://doi.org/10.1042/BST20210959

Published: 15 February 2022

View article titled, Whole-genome methods to define DNA and histone accessibility and long-range interactions in chromatin

Articles

Multiple roles of Pol epsilon in eukaryotic chromosome replication

Milos A. Cvetkovic, Esther Ortega, Roberto Bellelli, Alessandro Costa

Biochem Soc Trans (2022) 50 (1): 309–320.

https://doi.org/10.1042/BST20210082

Published: 07 February 2022

View article titled, Multiple roles of Pol epsilon in eukaryotic chromosome replication

Articles

Artificial protein assemblies with well-defined supramolecular protein nanostructures

Suyeong Han, Yongwon Jung

Biochem Soc Trans (2021) 49 (6): 2821–2830.

https://doi.org/10.1042/BST20210808

Published: 23 November 2021

View article titled, Artificial protein assemblies with well-defined supramolecular protein nanostructures

Articles

Writing and erasing O- GlcNAc from target proteins in cells

Yun Ge, Christina M. Woo

Biochem Soc Trans (2021) 49 (6): 2891–2901.

https://doi.org/10.1042/BST20210865

Published: 16 November 2021

View article titled, Writing and erasing O- GlcNAc from target proteins in cells

Articles

Live-cell visualization of cytochrome c : a tool to explore apoptosis

João Pessoa

Biochem Soc Trans (2021) 49 (6): 2903–2915.

https://doi.org/10.1042/BST20211028

Published: 08 November 2021

View article titled, Live-cell visualization of cytochrome c : a tool to explore apoptosis

Articles

Challenges and approaches to studying pore-forming proteins

Joshua T. Benton, Charles Bayly-Jones

Biochem Soc Trans (2021) 49 (6): 2749–2765.

https://doi.org/10.1042/BST20210706

Published: 08 November 2021

View article titled, Challenges and approaches to studying pore-forming proteins

Articles

TOP2B's contributions to transcription

Caroline A. Austin, Ian G. Cowell, Mushtaq M. Khazeem, Dawn Lok, Huei Teng Ng

Biochem Soc Trans (2021) 49 (6): 2483–2493.

https://doi.org/10.1042/BST20200454

Published: 08 November 2021

View article titled, TOP2B's contributions to transcription

Articles

Conquer by cryo-EM without physically dividing

Gabriel C. Lander, Robert M. Glaeser

Biochem Soc Trans (2021) 49 (5): 2287–2298.

https://doi.org/10.1042/BST20210360

Published: 28 October 2021

View article titled, Conquer by cryo-EM without physically dividing

Articles

Controlled metabolic cascades for protein synthesis in an artificial cell

Huong Thanh Nguyen, Sungwoo Lee, Kwanwoo Shin

Biochem Soc Trans (2021) 49 (5): 2143–2151.

https://doi.org/10.1042/BST20210175

Published: 08 October 2021

View article titled, Controlled metabolic cascades for protein synthesis in an artificial cell

Articles

Profiling novel pharmacology of receptor complexes using Receptor-HIT

Elizabeth K.M. Johnstone, Kevin D.G. Pfleger

Biochem Soc Trans (2021) 49 (4): 1555–1565.

https://doi.org/10.1042/BST20201110

Published: 26 August 2021

View article titled, Profiling novel pharmacology of receptor complexes using Receptor-HIT

Articles

The use of fluorescence correlation spectroscopy to characterise the molecular mobility of G protein-coupled receptors in membrane microdomains: an update

Laura E. Kilpatrick, Stephen J. Hill

Biochem Soc Trans (2021) 49 (4): 1547–1554.

https://doi.org/10.1042/BST20201001

Published: 26 August 2021

View article titled, The use of fluorescence correlation spectroscopy to characterise the molecular mobility of G protein-coupled receptors in membrane microdomains: an update

Articles

Advances in microglia cellular models: focus on extracellular vesicle production

Lorenzo Ceccarelli, Laura Marchetti, Chiara Giacomelli, Claudia Martini

Biochem Soc Trans (2021) 49 (4): 1791–1802.

https://doi.org/10.1042/BST20210203

Published: 20 August 2021

View article titled, Advances in microglia cellular models: focus on extracellular vesicle production

Articles

Methods for the solubilisation of membrane proteins: the micelle-aneous world of membrane protein solubilisation

Giedre Ratkeviciute, Benjamin F. Cooper, Timothy J. Knowles

Biochem Soc Trans (2021) 49 (4): 1763–1777.

https://doi.org/10.1042/BST20210181

Published: 20 August 2021

View article titled, Methods for the solubilisation of membrane proteins: the micelle-aneous world of membrane protein solubilisation

Articles

Solid state NMR of membrane proteins: methods and applications

Vivien Yeh, Boyan B. Bonev

Biochem Soc Trans (2021) 49 (4): 1505–1513.

https://doi.org/10.1042/BST20200070

Published: 16 August 2021

View article titled, Solid state NMR of membrane proteins: methods and applications

Articles

Organ-on-chip applications in drug discovery: an end user perspective

Naomi Clapp, Augustin Amour, Wendy C. Rowan, Pelin L. Candarlioglu

Biochem Soc Trans (2021) 49 (4): 1881–1890.

https://doi.org/10.1042/BST20210840

Published: 16 August 2021

View article titled, Organ-on-chip applications in drug discovery: an end user perspective

Articles

Single-molecule fluorescence vistas of how lipids regulate membrane proteins

Alyssa E. Ward, Yujie Ye, Jennifer A. Schuster, Shushu Wei, Francisco N. Barrera

Biochem Soc Trans (2021) 49 (4): 1685–1694.

https://doi.org/10.1042/BST20201074

Published: 04 August 2021

View article titled, Single-molecule fluorescence vistas of how lipids regulate membrane proteins

Articles

The Hitchhiker's guide to glycoproteomics

Tiago Oliveira, Morten Thaysen-Andersen, Nicolle H. Packer, Daniel Kolarich

Biochem Soc Trans (2021) 49 (4): 1643–1662.

https://doi.org/10.1042/BST20200879

Published: 20 July 2021

View article titled, The Hitchhiker's guide to glycoproteomics

Articles

Unravelling the structural complexity of protein–lipid interactions with neutron reflectometry

Luke A. Clifton

Biochem Soc Trans (2021) 49 (4): 1537–1546.

https://doi.org/10.1042/BST20201071

Published: 09 July 2021

View article titled, Unravelling the structural complexity of protein–lipid interactions with neutron reflectometry

Articles

Protein-fragment complementation assays for large-scale analysis of protein–protein interactions

Ewa Blaszczak, Natalia Lazarewicz, Aswani Sudevan, Robert Wysocki, Gwenaël Rabut

Biochem Soc Trans (2021) 49 (3): 1337–1348.

https://doi.org/10.1042/BST20201058

Published: 22 June 2021

View article titled, Protein-fragment complementation assays for large-scale analysis of protein–protein interactions

Articles

Biological insights from SMA-extracted proteins

Lucas Unger, Alejandro Ronco-Campaña, Philip Kitchen, Roslyn M. Bill, Alice J. Rothnie

Biochem Soc Trans (2021) 49 (3): 1349–1359.

https://doi.org/10.1042/BST20201067

Published: 10 June 2021

View article titled, Biological insights from SMA-extracted proteins

Articles

New insights into promoter–enhancer communication mechanisms revealed by dynamic single-molecule imaging

Jieru Li, Alexandros Pertsinidis

Biochem Soc Trans (2021) 49 (3): 1299–1309.

https://doi.org/10.1042/BST20200963

Published: 01 June 2021

View article titled, New insights into promoter–enhancer communication mechanisms revealed by dynamic single-molecule imaging

Articles

Methodology to detect oxidised phospholipids and their relevance in disease

Ahilanandan Dushianthan, Anthony Postle

Biochem Soc Trans (2021) 49 (3): 1241–1250.

https://doi.org/10.1042/BST20200852

Published: 07 May 2021

View article titled, Methodology to detect oxidised phospholipids and their relevance in disease

Articles

What's in a mass?

Juan J. Calvete, Libia Sanz, Diana Mora-Obando, Bruno Lomonte, Anita M. Tanaka-Azevedo, Karen de Morais-Zani, Sávio S. Sant'Anna, Cleópatra A.S. Caldeira

Biochem Soc Trans (2021) 49 (2): 1027–1037.

https://doi.org/10.1042/BST20210288

Published: 30 April 2021

View article titled, What's in a mass?

Articles

Chemical reporters to study mammalian O-glycosylation

Kathryn E. Huxley, Lianne I. Willems

Biochem Soc Trans (2021) 49 (2): 903–913.

https://doi.org/10.1042/BST20200839

Published: 16 April 2021

View article titled, Chemical reporters to study mammalian O-glycosylation

Articles

Collagen hydroxylysine glycosylation: non-conventional substrates for atypical glycosyltransferase enzymes

Francesca De Giorgi, Marco Fumagalli, Luigi Scietti, Federico Forneris

Biochem Soc Trans (2021) 49 (2): 855–866.

https://doi.org/10.1042/BST20200767

Published: 11 March 2021

View article titled, Collagen hydroxylysine glycosylation: non-conventional substrates for atypical glycosyltransferase enzymes

Articles

Advances in modelling the human microbiome–gut–brain axis in vitro

Chrysanthi-Maria Moysidou, Róisín M. Owens

Biochem Soc Trans (2021) 49 (1): 187–201.

https://doi.org/10.1042/BST20200338

Published: 05 February 2021

View article titled, Advances in modelling the human microbiome–gut–brain axis in vitro

Articles

The search for RNA-binding proteins: a technical and interdisciplinary challenge

Jeffrey M. Smith, Jarrod J. Sandow, Andrew I. Webb

Biochem Soc Trans (2021) 49 (1): 393–403.

https://doi.org/10.1042/BST20200688

Published: 25 January 2021

View article titled, The search for RNA-binding proteins: a technical and interdisciplinary challenge

Articles

A mass spectrometry-based glycotope-centric cellular glycomics is the more fruitful way forward to see the forest for the trees

Kay-Hooi Khoo

Biochem Soc Trans (2021) 49 (1): 55–69.

https://doi.org/10.1042/BST20190861

Published: 25 January 2021

View article titled, A mass spectrometry-based glycotope-centric cellular glycomics is the more fruitful way forward to see the forest for the trees

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