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MILES D HOUSLAY
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Articles

Identification and characterization of small-molecule ligands that maintain pluripotency of human embryonic stem cells

Peter Burton, David R. Adams, Achamma Abraham, Robert W. Allcock, Zhong Jiang, Angela McCahill, Jane Gilmour, John McAbney, Nicole M. Kane, George S. Baillie, Fergus R. McKenzie, Andrew H. Baker, Miles D. Houslay, Joanne C. Mountford, Graeme Milligan
Journal: Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (4): 1058–1061.
https://doi.org/10.1042/BST0381058
Published: 26 July 2010
View article titled, Identification and characterization of small-molecule ligands that maintain pluripotency of human embryonic stem cells
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Articles

136 Antisense technology reveals distinct roles for protein kinase C isoforms during 3T3-F442A preadipocyte differentiation

IONA M. FLEMING, SIMON J. MacKENZIE, MILES D. HOUSLAY, RICHARD G. VERNON, ELAINE KILGOUR
Journal: Biochemical Society Transactions
Biochem Soc Trans (1997) 25 (4): S665.
https://doi.org/10.1042/bst025s665
Published: 01 November 1997
View article titled, 136 Antisense technology reveals distinct roles for protein kinase C isoforms during 3T3-F442A preadipocyte differentiation
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Articles

143 Development of lipid metabolism in ovine preadipocytes in vitro

BEATRIZ SORET, SHONA E. MELROSE, ERIC FINLEY, MAUREEN T. TRAVERS, MILES D. HOUSLAY, RICHARD G. VERNON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1997) 25 (4): S671.
https://doi.org/10.1042/bst025s671
Published: 01 November 1997
View article titled, 143 Development of lipid metabolism in ovine preadipocytes in vitro
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Articles

Modulation of adenosine signalling in sheep adipose tissue by growth hormone

ROSEMARIE DORIS, ELAINE KILGOUR, MILES D. HOUSLAY, GORDON E. THOMPSON, RICHARD G. VERNON
Journal: Biochemical Society Transactions
Biochem Soc Trans (1995) 23 (1): 16S.
https://doi.org/10.1042/bst023016s
Published: 01 February 1995
View article titled, Modulation of adenosine signalling in sheep adipose tissue by growth hormone
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Articles

Growth hormone suppresses the expression of G 12 in rat adipocytes

ROSEMARIE DORIS, RICHARD G. VERNON, MILES D. HOUSLAY, ELAINE KILGOUR
Journal: Biochemical Society Transactions
Biochem Soc Trans (1993) 21 (4): 432S.
https://doi.org/10.1042/bst021432s
Published: 01 November 1993
View article titled, Growth hormone suppresses the expression of G 12 in rat adipocytes
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Articles

Regulation of intracellular cyclic AMP concentrations in hepatocytes involves the integrated activation and desensitization of adenylyl cyclase coupled with the action and activation of specific isoforms of cyclic AMP phosphodiesterase

Miles D. Houslay, Susanne L. Griffiths, Yvonne M. Horton, Callum Livingstone, Margaret Lobban, Fiona Macdonald, Nicholas Morris, James Pryde, Grant Scotland, Yasmin Shakur, Gary Sweeney, Eric K. Y. Tang
Journal: Biochemical Society Transactions
Biochem Soc Trans (1992) 20 (1): 140–146.
https://doi.org/10.1042/bst0200140
Published: 01 February 1992
View article titled, Regulation of intracellular cyclic AMP concentrations in hepatocytes involves the integrated activation and desensitization of adenylyl cyclase coupled with the action and activation of specific isoforms of cyclic AMP phosphodiesterase
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Articles

G-protein α-subunit mRNAs in diabetic rat tissues

SUSANNE L. GRIFFITHS, MILES D. HOUSLAY
Journal: Biochemical Society Transactions
Biochem Soc Trans (1990) 18 (3): 475–476.
https://doi.org/10.1042/bst0180475
Published: 01 June 1990
View article titled, G-protein α-subunit mRNAs in diabetic rat tissues
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Articles

Regulation of the phosphorylation state of G i 2 in intact rat hepatocytes

MARK BUSHFIELD, MILES D. HOUSLAY
Journal: Biochemical Society Transactions
Biochem Soc Trans (1990) 18 (3): 456.
https://doi.org/10.1042/bst0180456
Published: 01 June 1990
View article titled, Regulation of the phosphorylation state of G i 2 in intact rat hepatocytes
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Articles

Proteolysis of the 52 kDa, insulin-stimulated, peripheral, plasma-membrane cyclic AMP-specific phosphodiesterase

NIGEL J. PYNE, ROWENA STEVENS, MILES D. HOUSLAY
Journal: Biochemical Society Transactions
Biochem Soc Trans (1989) 17 (4): 666–667.
https://doi.org/10.1042/bst0170666
Published: 01 August 1989
View article titled, Proteolysis of the 52 kDa, insulin-stimulated, peripheral, plasma-membrane cyclic AMP-specific phosphodiesterase
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Articles

Expression of G-protein β-subunit in lean and obese Zucker rats and streptozotocin-induced diabetic and normal rats

NIGEL J. PYNE, GRAEME MILLIGAN, MILES D. HOUSLAY
Journal: Biochemical Society Transactions
Biochem Soc Trans (1989) 17 (4): 667–668.
https://doi.org/10.1042/bst0170667
Published: 01 August 1989
View article titled, Expression of G-protein β-subunit in lean and obese Zucker rats and streptozotocin-induced diabetic and normal rats
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Articles

Guanine nucleotide regulatory proteins in insulin's action and in diabetes

MILES D. HOUSLAY, NIGEL J. PYNE, RICHARD M. O'BRIEN, KENNETH SIDDLE, DEREK STRASSHEIM, TIMOTHY PALMER, SANDRA SPENCE, MARY WOODS, ANDREW WILSON, BRIAN LAVAN, GREGORY J. MURPHY, MARK SAVILLE, MARY-ANNE McGREGOR, ELAINE KILGOUR, NEIL ANDERSON, JOHN T. KNOWLER, SUSANNE GRIFFITHS, GRAEME MILLIGAN
Journal: Biochemical Society Transactions
Biochem Soc Trans (1989) 17 (4): 627–629.
https://doi.org/10.1042/bst0170627
Published: 01 August 1989
View article titled, Guanine nucleotide regulatory proteins in insulin's action and in diabetes
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Articles

The insulin-sensitivity of phosphodiesterase activities released by hypotonic extraction of hepatocyte particulate fractions

NEIL G. ANDERSON, MILES D. HOUSLAY
Journal: Biochemical Society Transactions
Biochem Soc Trans (1989) 17 (1): 217.
https://doi.org/10.1042/bst0170217
Published: 01 February 1989
View article titled, The insulin-sensitivity of phosphodiesterase activities released by hypotonic extraction of hepatocyte particulate fractions
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Articles

Activation of the ‘dense-vesicle” cyclic AMP-phosphodiesterase from rat liver by cyclic AMP-dependent protein kinase

ELAINE KILGOUR, NEIL G. ANDERSON, MILES D. HOUSLAY
Journal: Biochemical Society Transactions
Biochem Soc Trans (1988) 16 (6): 1025–1026.
https://doi.org/10.1042/bst0161025
Published: 01 December 1988
View article titled, Activation of the ‘dense-vesicle” cyclic AMP-phosphodiesterase from rat liver by cyclic AMP-dependent protein kinase
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Articles

The role of N- ras p21 in the coupling of growth factor receptors to inositol phospholipid turnover

MICHAEL J. O. WAKELAM, MILES D. HOUSLAY, SHIREEN A. DAVIES, CHRISTOPHER J. MARSHALL, ALAN HALL
Journal: Biochemical Society Transactions
Biochem Soc Trans (1987) 15 (1): 45–47.
https://doi.org/10.1042/bst0150045
Published: 01 February 1987
View article titled, The role of N- ras p21 in the coupling of growth factor receptors to inositol phospholipid turnover
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Articles

Glucagon stimulates adenylate cyclase through GR2 glucagon receptors: a process which can be attenuated by glucagon stimulating inositol phospholipid metabolism through GR1 glucagon receptors

MILES D HOUSLAY, MICHAEL J. O. WAKELAM, GREGORY J. MURPHY, DEBRA J. GAWLER, NIGEL J. PYNE
Journal: Biochemical Society Transactions
Biochem Soc Trans (1987) 15 (1): 21–24.
https://doi.org/10.1042/bst0150021
Published: 01 February 1987
View article titled, Glucagon stimulates adenylate cyclase through GR2 glucagon receptors: a process which can be attenuated by glucagon stimulating inositol phospholipid metabolism through GR1 glucagon receptors
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Articles

A novel method for the purification of the insulin-activated peripheral plasma membrane, high-affinity cyclic AMP phosphodiesterase

NIGEL J. PYNE, MICHAEL E. COOPER, HUGH G. NIMMO, MILES D. HOUSLAY
Journal: Biochemical Society Transactions
Biochem Soc Trans (1986) 14 (6): 1016.
https://doi.org/10.1042/bst0141016
Published: 01 December 1986
View article titled, A novel method for the purification of the insulin-activated peripheral plasma membrane, high-affinity cyclic AMP phosphodiesterase
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Articles

Insulin, glucagon and the receptor-mediated control of cyclic AMP concentrations in liver

MILES D. HOUSLAY
Journal: Biochemical Society Transactions
Biochem Soc Trans (1986) 14 (2): 183–193.
https://doi.org/10.1042/bst0140183
Published: 01 April 1986
View article titled, Insulin, glucagon and the receptor-mediated control of cyclic AMP concentrations in liver
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Articles

Does insulin exert certain of its actions through a distinct species of guanine nucleotide regulatory protein?

MILES D. HOUSLAY, ALAN V. WALLACE, MICHAEL E. COOPER, NIGEL J. PAYNE, SALLY R. WILSON, CLARE M. HEYWORTH
Journal: Biochemical Society Transactions
Biochem Soc Trans (1984) 12 (5): 766–768.
https://doi.org/10.1042/bst0120766
Published: 01 October 1984
View article titled, Does insulin exert certain of its actions through a distinct species of guanine nucleotide regulatory protein?
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Articles

Insulin activates a rat liver peripheral plasma-membrane cyclic AMP phosphodiesterase by a phosphorylation mechanism

ROBERT J. MARCHMONT, MILES D. HOUSLAY
Journal: Biochemical Society Transactions
Biochem Soc Trans (1980) 8 (5): 537–538.
https://doi.org/10.1042/bst0080537
Published: 01 October 1980
View article titled, Insulin activates a rat liver peripheral plasma-membrane cyclic AMP phosphodiesterase by a phosphorylation mechanism
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Articles

Coupling of the Glucagon Receptor to Adenylate Cyclase

MILES D. HOUSLAY
Journal: Biochemical Society Transactions
Biochem Soc Trans (1979) 7 (5): 843–846.
https://doi.org/10.1042/bst0070843
Published: 01 October 1979
View article titled, Coupling of the Glucagon Receptor to Adenylate Cyclase
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