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Issues
December 2019
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Cover Image
Cover Image
The second messenger 3′,5′-cyclic nucleoside adenosine monophosphate (cAMP) plays a key role in signal transduction across prokaryotes and eukaryotes. In this issue Klausen and colleagues (1733–1748) provide an overview about the optogenetic tools and biosensors used to explore the subcellular organization of cAMP signalling. The cover image depicts time projection (colour represents time) of a head-tethered transgenic mouse sperm expressing the photo-activated adenylate cyclase bPAC. Image courtesy of Dagmar Wachten.
ISSN 0300-5127
EISSN 1470-8752
In this Issue
Review Articles
Bacterial glycans and their interactions with lectins in the innate immune system
Biochem Soc Trans (2019) 47 (6): 1569–1579.
New insights into the evolutionary conservation of the sole PIKK pseudokinase Tra1/TRRAP
Biochem Soc Trans (2019) 47 (6): 1597–1608.
Structural mechanism of DNA-end synapsis in the non-homologous end joining pathway for repairing double-strand breaks: bridge over troubled ends
Biochem Soc Trans (2019) 47 (6): 1609–1619.
The evolution of spherical cell shape; progress and perspective
Biochem Soc Trans (2019) 47 (6): 1621–1634.
High spatiotemporal resolution and low photo-toxicity fluorescence imaging in live cells and in vivo
Biochem Soc Trans (2019) 47 (6): 1635–1650.
Immunomodulatory role of the extracellular matrix protein tenascin-C in neuroinflammation
Biochem Soc Trans (2019) 47 (6): 1651–1660.
Understanding the mechanisms that determine extracellular matrix remodeling in the infarcted myocardium
Biochem Soc Trans (2019) 47 (6): 1679–1687.
3D multicellular models to study the regulation and roles of acid–base transporters in breast cancer
Biochem Soc Trans (2019) 47 (6): 1689–1700.
The non-receptor tyrosine kinase ACK: regulatory mechanisms, signalling pathways and opportunities for attACKing cancer
Biochem Soc Trans (2019) 47 (6): 1715–1731.
Elucidating cyclic AMP signaling in subcellular domains with optogenetic tools and fluorescent biosensors
Biochem Soc Trans (2019) 47 (6): 1733–1747.
Impact of pharmacological agents on mitochondrial function: a growing opportunity?
Biochem Soc Trans (2019) 47 (6): 1757–1772.
Engineering of industrially important microorganisms for assimilation of cellulosic biomass: towards consolidated bioprocessing
Biochem Soc Trans (2019) 47 (6): 1781–1794.
Regulation of FKBP51 and FKBP52 functions by post-translational modifications
Cristina Daneri-Becerra; Nadia R. Zgajnar; Cecilia M. Lotufo; Ana B. Ramos Hryb; Graciela Piwien-Pilipuk; Mario D. Galigniana
Biochem Soc Trans (2019) 47 (6): 1815–1831.
Chloride transporters and channels in β-cell physiology: revisiting a 40-year-old model
Biochem Soc Trans (2019) 47 (6): 1843–1855.
Ubiquitin-specific protease 8 (USP8/UBPy): a prototypic multidomain deubiquitinating enzyme with pleiotropic functions
Biochem Soc Trans (2019) 47 (6): 1867–1879.
Beyond reversal: ubiquitin and ubiquitin-like proteases and the orchestration of the DNA double strand break repair response
Biochem Soc Trans (2019) 47 (6): 1881–1893.
Methylotrophic methanogens everywhere — physiology and ecology of novel players in global methane cycling
Biochem Soc Trans (2019) 47 (6): 1895–1907.
The furanosidic scaffold of d-ribose: a milestone for cell life
Antonella Del-Corso; Mario Cappiello; Roberta Moschini; Francesco Balestri; Umberto Mura; Piero Luigi Ipata
Biochem Soc Trans (2019) 47 (6): 1931–1940.
Multitalented actors inside and outside the cell: recent discoveries add to the number of moonlighting proteins
Biochem Soc Trans (2019) 47 (6): 1941–1948.
The ‘dark matter’ of ubiquitin-mediated processes: opportunities and challenges in the identification of ubiquitin-binding domains
Biochem Soc Trans (2019) 47 (6): 1949–1962.