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Issues

Volume 47, Issue 5
October 2019
Issue Cover
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  • Cover Image

    Cover Image

    issue cover

    The cover image depicts immunofluorescence analysis of Multimerin-2 expression in the vessels of the gastric mucosa. Multimerin-2 is downregulated in various types of cancer. In this issue Mongiat and colleagues (1543–1565) discuss the role of the extracellular matrix as a gatekeeper, regulating tumour angiogenesis. Image courtesy of Maurizio Mongiat.

ISSN 0300-5127
EISSN 1470-8752
In this Issue

Review Articles

Targeting centrosome amplification, an Achilles' heel of cancer
Dorota Sabat-Pośpiech; Kim Fabian-Kolpanowicz; Ian A. Prior; Judy M. Coulson; Andrew B. Fielding
Biochem Soc Trans (2019) 47 (5): 1209–1222.
View Articletitled, Targeting centrosome amplification, an Achilles' heel of cancer
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Applications of catalyzed cytoplasmic disulfide bond formation
Mirva J. Saaranen; Lloyd W. Ruddock
Biochem Soc Trans (2019) 47 (5): 1223–1231.
View Articletitled, Applications of catalyzed cytoplasmic disulfide bond formation
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Designing minimalist membrane proteins
Paul Curnow
Biochem Soc Trans (2019) 47 (5): 1233–1245.
View Articletitled, Designing minimalist membrane proteins
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Structural dynamics of P-type ATPase ion pumps
Mateusz Dyla; Sara Basse Hansen; Poul Nissen; Magnus Kjaergaard
Biochem Soc Trans (2019) 47 (5): 1247–1257.
View Articletitled, Structural dynamics of P-type ATPase ion pumps
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ABCG5/G8: a structural view to pathophysiology of the hepatobiliary cholesterol secretion
Aiman A. Zein; Rupinder Kaur; Toka O.K. Hussein; Gregory A. Graf; Jyh-Yeuan Lee
Biochem Soc Trans (2019) 47 (5): 1259–1268.
View Articletitled, ABCG5/G8: a structural view to pathophysiology of the hepatobiliary cholesterol secretion
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Multifaceted roles of porin in mitochondrial protein and lipid transport
Toshiya Endo; Haruka Sakaue
Biochem Soc Trans (2019) 47 (5): 1269–1277.
View Articletitled, Multifaceted roles of porin in mitochondrial protein and lipid transport
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Reprogramming bacteria with RNA regulators
Patrícia Apura; Susana Domingues; Sandra C. Viegas; Cecília M. Arraiano
Biochem Soc Trans (2019) 47 (5): 1279–1289.
View Articletitled, Reprogramming bacteria with RNA regulators
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How is the acyl chain composition of phosphoinositides created and does it matter?
David Barneda; Sabina Cosulich; Len Stephens; Phillip Hawkins
Biochem Soc Trans (2019) 47 (5): 1291–1305.
View Articletitled, How is the acyl chain composition of phosphoinositides created and does it matter?
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Bone marrow niche crosses paths with BMPs: a road to protection and persistence in CML
Caroline Busch; Helen Wheadon
Biochem Soc Trans (2019) 47 (5): 1307–1325.
View Articletitled, Bone marrow niche crosses paths with BMPs: a road to protection and persistence in CML
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cGMP signalling in cardiomyocyte microdomains
Nadja I. Bork; Cristina E. Molina; Viacheslav O. Nikolaev
Biochem Soc Trans (2019) 47 (5): 1327–1339.
View Articletitled, cGMP signalling in cardiomyocyte microdomains
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The role of A-kinase anchoring proteins in cardiac oxidative stress
Dario Diviani; Halima Osman; Marion Delaunay; Simon Kaiser
Biochem Soc Trans (2019) 47 (5): 1341–1353.
View Articletitled, The role of A-kinase anchoring proteins in cardiac oxidative stress
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Swimming regulations for protein kinase A catalytic subunit
Matthew G. Gold
Biochem Soc Trans (2019) 47 (5): 1355–1366.
View Articletitled, Swimming regulations for protein kinase A catalytic subunit
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Evolving mtDNA populations within cells
Iain G. Johnston; Joerg P. Burgstaller
Biochem Soc Trans (2019) 47 (5): 1367–1382.
View Articletitled, Evolving mtDNA populations within cells
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Imaging cAMP nanodomains in the heart
Ying-Chi Chao; Nicoletta C. Surdo; Sergio Pantano; Manuela Zaccolo
Biochem Soc Trans (2019) 47 (5): 1383–1392.
View Articletitled, Imaging cAMP nanodomains in the heart
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POPDC proteins and cardiac function
Thomas Brand
Biochem Soc Trans (2019) 47 (5): 1393–1404.
View Articletitled, POPDC proteins and cardiac function
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Reshaping cAMP nanodomains through targeted disruption of compartmentalised phosphodiesterase signalosomes
Connor M. Blair; George S. Baillie
Biochem Soc Trans (2019) 47 (5): 1405–1414.
View Articletitled, Reshaping cAMP nanodomains through targeted disruption of compartmentalised phosphodiesterase signalosomes
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Selective small-molecule EPAC activators
Urszula Luchowska-Stańska; David Morgan; Stephen J. Yarwood; Graeme Barker
Biochem Soc Trans (2019) 47 (5): 1415–1427.
View Articletitled, Selective small-molecule EPAC activators
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Mammalian mitochondrial translation — revealing consequences of divergent evolution
Rawaa A. Z. Al-Faresi; Robert. N. Lightowlers; Zofia M. A. Chrzanowska-Lightowlers
Biochem Soc Trans (2019) 47 (5): 1429–1436.
View Articletitled, Mammalian mitochondrial translation — revealing consequences of divergent evolution
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Molecular pathways of mitochondrial outer membrane protein degradation
Jing Zheng; Lanlan Li; Hui Jiang
Biochem Soc Trans (2019) 47 (5): 1437–1447.
View Articletitled, Molecular pathways of mitochondrial outer membrane protein degradation
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The role of ligand-gated conformational changes in enzyme catalysis
Cátia Moreira; Ana Rita Calixto; John P. Richard; Shina Caroline Lynn Kamerlin
Biochem Soc Trans (2019) 47 (5): 1449–1460.
View Articletitled, The role of ligand-gated conformational changes in enzyme catalysis
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Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes
Mark A. Watson; Hoi-Shan Wong; Martin D. Brand
Biochem Soc Trans (2019) 47 (5): 1461–1469.
View Articletitled, Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes
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Fostering open collaboration in drug development for paediatric brain tumours
Jong Fu Wong; Elizabeth J. Brown; Eleanor Williams; Alex N. Bullock
Biochem Soc Trans (2019) 47 (5): 1471–1479.
View Articletitled, Fostering open collaboration in drug development for paediatric brain tumours
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Towards a model of GCN2 activation
Glenn R. Masson
Biochem Soc Trans (2019) 47 (5): 1481–1488.
View Articletitled, Towards a model of GCN2 activation
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Secondary structure of caveolins: a mini review
Kyle T. Root; Jeffrey A. Julien; Kerney Jebrell Glover
Biochem Soc Trans (2019) 47 (5): 1489–1498.
View Articletitled, Secondary structure of caveolins: a mini review
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Making the cut(s): how Cas12a cleaves target and non-target DNA
Daan C. Swarts
Biochem Soc Trans (2019) 47 (5): 1499–1510.
View Articletitled, Making the cut(s): how Cas12a cleaves target and non-target DNA
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RecA and DNA recombination: a review of molecular mechanisms
Elsa del Val; William Nasser; Hafid Abaibou; Sylvie Reverchon
Biochem Soc Trans (2019) 47 (5): 1511–1531.
View Articletitled, RecA and DNA recombination: a review of molecular mechanisms
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The fitness challenge of studying molecular adaptation
David Coombes; James W.B. Moir; Anthony M. Poole; Tim F. Cooper; Renwick C.J. Dobson
Biochem Soc Trans (2019) 47 (5): 1533–1542.
View Articletitled, The fitness challenge of studying molecular adaptation
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Extracellular matrix: the gatekeeper of tumor angiogenesis
Maurizio Mongiat; Simone Buraschi; Eva Andreuzzi; Thomas Neill; Renato V. Iozzo
Biochem Soc Trans (2019) 47 (5): 1543–1555.
View Articletitled, Extracellular matrix: the gatekeeper of tumor angiogenesis
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Understanding PDE4's function in Alzheimer's disease; a target for novel therapeutic approaches
Amy J. Tibbo; Gonzalo S. Tejeda; George S. Baillie
Biochem Soc Trans (2019) 47 (5): 1557–1565.
View Articletitled, Understanding PDE4's function in Alzheimer's disease; a target for novel therapeutic approaches
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Corrections

Correction: Glutamate transporters: a broad review of the most recent archaeal and human structures
Ana Pavić; Alexandra O. M. Holmes; Vincent L. G. Postis; Adrian Goldman
Biochem Soc Trans (2019) 47 (5): 1567.
View Articletitled, Correction: Glutamate transporters: a broad review of the most recent archaeal and human structures
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Submit your work
Developing high-affinity, oxygen-insensitive [NiFe]-hydrogenases as biocatalysts for energy conversion
Chemical catalysis by biological amyloids
A tail of their own: regulation of cardiolipin and phosphatidylinositol fatty acyl profile by the acyltransferase LCLAT1
Histone mutations in cancer
Insights into the function of cytoglobin
  • Online ISSN 1470-8752
  • Print ISSN 0300-5127

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