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December 2017
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Cover Image
Cover Image
Cryo-electron microscopy density map of a Cowpea Mosaic virus (CPMV) empty virus-like particle (eVLP) at 2.7 Å resolution (EMD-3952). The large (L) subunit is displayed in green and the small (S) subunit in blue. Five S subunits interact to form pronounced turrets at the 5-fold axis. Here we show a view down a two-fold axis. The eVLP was produced by transient co-expression in plants of the precursor of the L and S subunits (VP60) and the virus-encoded protease (24K) required for its processing. For further details, please see article by Lomonossoff et al, pages 1263–1269
ISSN 0300-5127
EISSN 1470-8752
In this Issue
Review Articles
Regulated intramembrane proteolysis: emergent role in cell signalling pathways
Biochem Soc Trans (2017) 45 (6): 1185–1202.
Platelet mitochondrial dysfunction and the correlation with human diseases
Biochem Soc Trans (2017) 45 (6): 1213–1223.
Biochemical targets of drugs mitigating oxidative stress via redox-independent mechanisms
Biochem Soc Trans (2017) 45 (6): 1225–1252.
Biomolecular coevolution and its applications: Going from structure prediction toward signaling, epistasis, and function
Biochem Soc Trans (2017) 45 (6): 1253–1261.
Combining high-resolution cryo-electron microscopy and mutagenesis to develop cowpea mosaic virus for bionanotechnology
Biochem Soc Trans (2017) 45 (6): 1263–1269.
SNARE phosphorylation: a control mechanism for insulin-stimulated glucose transport and other regulated exocytic events
Biochem Soc Trans (2017) 45 (6): 1271–1277.
Emerging candidate treatment strategies for Hutchinson-Gilford progeria syndrome
Biochem Soc Trans (2017) 45 (6): 1279–1293.
Transcriptional regulators of redox balance and other homeostatic processes with the potential to alter neurodegenerative disease trajectory
Biochem Soc Trans (2017) 45 (6): 1295–1303.
The devil is in the domain: understanding protein recognition of multiple RNA targets
Biochem Soc Trans (2017) 45 (6): 1305–1311.
Distinct RNA-unwinding mechanisms of DEAD-box and DEAH-box RNA helicase proteins in remodeling structured RNAs and RNPs
Biochem Soc Trans (2017) 45 (6): 1313–1321.
Autophagy in the context of the cellular membrane-trafficking system: the enigma of Atg9 vesicles
Biochem Soc Trans (2017) 45 (6): 1323–1331.
Breaking the scale: how disrupting the karyoplasmic ratio gives cancer cells an advantage for metastatic invasion
Biochem Soc Trans (2017) 45 (6): 1333–1344.
Corrections
Correction: Role of conformational change and K-path ligands in controlling cytochrome c oxidase activity
Biochem Soc Trans (2017) 45 (6): 1345.
