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December 2014
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ISSN 0300-5127
EISSN 1470-8752
Biochemical Society Focused Meetings
Protein Kinase C Signalling in Health and Disease
Imaging tumour heterogeneity of the consequences of a PKCα–substrate interaction in breast cancer patients
Gregory Weitsman; Katherine Lawler; Muireann T. Kelleher; James E. Barrett; Paul R. Barber; Eamon Shamil; Frederic Festy; Gargi Patel; Gilbert O. Fruhwirth; Lufei Huang; Iain D.C. Tullis; Natalie Woodman; Enyinnaya Ofo; Simon M. Ameer-Beg; Sheeba Irshad; John Condeelis; Cheryl E. Gillett; Paul A. Ellis; Borivoj Vojnovic; Anthony C.C. Coolen; Tony Ng
Biochem Soc Trans (2014) 42 (6): 1498–1505.
PKCη is an anti-apoptotic kinase that predicts poor prognosis in breast and lung cancer
Biochem Soc Trans (2014) 42 (6): 1519–1523.
Selective protein kinase Cθ (PKCθ) inhibitors for the treatment of autoimmune diseases
Adam Curnock; Clare Bolton; Peter Chiu; Elisabeth Doyle; Damien Fraysse; Matthias Hesse; Julie Jones; Peter Weber; Juan-Miguel Jimenez
Biochem Soc Trans (2014) 42 (6): 1524–1528.
Differential targeting of cPKC and nPKC decodes and regulates Ca2+ and lipid signalling
Biochem Soc Trans (2014) 42 (6): 1538–1542.
C1 domain-targeted isophthalates as protein kinase C modulators: structure-based design, structure–activity relationships and biological activities
Biochem Soc Trans (2014) 42 (6): 1543–1549.
Targeting PKCθ in skeletal muscle and muscle diseases: good or bad?
Valeria Marrocco; Piera Fiore; Luca Madaro; Annunziata Crupi; Biliana Lozanoska-Ochser; Marina Bouché
Biochem Soc Trans (2014) 42 (6): 1550–1555.
Angiogenesis and Vascular Remodelling: New Perspectives
Notch functions in developmental and tumour angiogenesis by diverse mechanisms1
Biochem Soc Trans (2014) 42 (6): 1563–1568.
Exploring the role of endothelium in the tumour response to anti-angiogenic therapy
Biochem Soc Trans (2014) 42 (6): 1569–1575.
VEGF, Notch and TGFβ/BMPs in regulation of sprouting angiogenesis and vascular patterning
Biochem Soc Trans (2014) 42 (6): 1576–1583.
The role of ERK5 in endothelial cell function
Gopika N. Nithianandarajah-Jones; Bettina Wilm; Christopher E.P. Goldring; Jürgen Müller; Michael J. Cross
Biochem Soc Trans (2014) 42 (6): 1584–1589.
Redefining the role(s) of endothelial αvβ3-integrin in angiogenesis
Biochem Soc Trans (2014) 42 (6): 1590–1595.
The development of anti-angiogenic heparan sulfate oligosaccharides
Biochem Soc Trans (2014) 42 (6): 1596–1600.
Mechanisms that influence tumour response to VEGF-pathway inhibitors
Biochem Soc Trans (2014) 42 (6): 1601–1607.
The emerging quest for the optimal angiostatic combination therapy
Arjan W. Griffioen; Andrea Weiss; Robert H. Berndsen; U. Kulsoom Abdul; Marije T. te Winkel; Patrycja Nowak-Sliwinska
Biochem Soc Trans (2014) 42 (6): 1608–1615.
Capillary growth in human skeletal muscle: physiological factors and the balance between pro-angiogenic and angiostatic factors
Biochem Soc Trans (2014) 42 (6): 1616–1622.
Split for the cure: VEGF, PDGF-BB and intussusception in therapeutic angiogenesis
Biochem Soc Trans (2014) 42 (6): 1637–1642.
The glioblastoma vasculature as a target for cancer therapy
Biochem Soc Trans (2014) 42 (6): 1647–1652.
Therapeutic vaccination targeting the tumour vasculature
Biochem Soc Trans (2014) 42 (6): 1653–1657.
Regulation of neovascularization by S-glutathionylation via the Wnt5a/sFlt-1 pathway
Biochem Soc Trans (2014) 42 (6): 1665–1670.
The Biological and Biomedical Consequences of Protein Moonlighting
Can bioinformatics help in the identification of moonlighting proteins?
Sergio Hernández; Alejandra Calvo; Gabriela Ferragut; Luís Franco; Antoni Hermoso; Isaac Amela; Antonio Gómez; Enrique Querol; Juan Cedano
Biochem Soc Trans (2014) 42 (6): 1692–1697.
The evolution of protein moonlighting: adaptive traps and promiscuity in the chaperonins
Biochem Soc Trans (2014) 42 (6): 1709–1714.
Peptidylprolyl cis–trans isomerases of Legionella pneumophila: virulence, moonlighting and novel therapeutic targets
Biochem Soc Trans (2014) 42 (6): 1728–1733.
Immunoglobulin heavy-chain-binding protein (BiP): a stress protein that has the potential to be a novel therapy for rheumatoid arthritis
Biochem Soc Trans (2014) 42 (6): 1752–1755.
Chemical genetics and its application to moonlighting in glycolytic enzymes
Biochem Soc Trans (2014) 42 (6): 1756–1761.
Comparison of moonlighting guanylate cyclases: roles in signal direction?
Biochem Soc Trans (2014) 42 (6): 1773–1779.
Moonlighting and pleiotropy within two regulators of the degradation machinery: the proteasome lid and the CSN
Biochem Soc Trans (2014) 42 (6): 1786–1791.
Fructose-1,6-bisphosphate aldolase (FBA)–a conserved glycolytic enzyme with virulence functions in bacteria: ‘ill met by moonlight’
Biochem Soc Trans (2014) 42 (6): 1792–1795.
Protein moonlighting in iron metabolism: glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
Biochem Soc Trans (2014) 42 (6): 1796–1801.
