Skip Nav Destination
Issues
August 2014
- Cover Image
- PDF Icon PDF LinkFront Matter
- PDF Icon PDF LinkTable of Contents
ISSN 0300-5127
EISSN 1470-8752
In this Issue
Biochemical Society Awards
GlaxoSmithKline Award Lecture
Biochemical Society Focused Meetings
Signalling and Acquired Resistance to Targeted Cancer Therapeutics
MAPK pathway inhibition in melanoma: resistance three ways
Biochem Soc Trans (2014) 42 (4): 727–732.
Anticipating mechanisms of resistance to PI3K inhibition in breast cancer: a challenge in the era of precision medicine
Biochem Soc Trans (2014) 42 (4): 733–741.
Understanding life and death decisions in human leukaemias
David J. MacEwan; Lawrence N. Barrera; Sujitra Keadsanti; Stuart A. Rushworth; Niraj M. Shah; Tianma Yuan; Lyubov Zaitseva
Biochem Soc Trans (2014) 42 (4): 747–751.
Adaptive protein and phosphoprotein networks which promote therapeutic sensitivity or acquired resistance
Biochem Soc Trans (2014) 42 (4): 758–764.
Assessing adaptation of the cancer kinome in response to targeted therapies
Biochem Soc Trans (2014) 42 (4): 765–769.
Consequences of feedback in signal transduction for targeted therapies
Biochem Soc Trans (2014) 42 (4): 770–775.
Intrinsic and acquired resistance to MEK1/2 inhibitors in cancer
Biochem Soc Trans (2014) 42 (4): 776–783.
Approaches for measuring signalling plasticity in the context of resistance to targeted cancer therapies
Biochem Soc Trans (2014) 42 (4): 791–797.
The role of the bone morphogenetic proteins in leukaemic stem cell persistence
Biochem Soc Trans (2014) 42 (4): 809–815.
One Hippo and many masters: differential regulation of the Hippo pathway in cancer
Biochem Soc Trans (2014) 42 (4): 816–821.
A role for the pseudokinase HER3 in the acquired resistance against EGFR- and HER2-directed targeted therapy
Biochem Soc Trans (2014) 42 (4): 831–836.
Behaviour Meets Biochemistry: Animals Making Sense of Molecules Making Scents
The complexity of protein semiochemistry in mammals
Robert J. Beynon; Stuart D. Armstrong; Guadalupe Gómez-Baena; Victoria Lee; Deborah Simpson; Jennifer Unsworth; Jane L. Hurst
Biochem Soc Trans (2014) 42 (4): 837–845.
Selection shaped the evolution of mouse androgen-binding protein (ABP) function and promoted the duplication of Abp genes
Biochem Soc Trans (2014) 42 (4): 851–860.
Do you smell what I smell? Genetic variation in olfactory perception
Biochem Soc Trans (2014) 42 (4): 861–865.
Structure and function of a peptide pheromone family that stimulate the vomeronasal sensory system in mice
Biochem Soc Trans (2014) 42 (4): 873–877.
Female puberty acceleration by male odour in mice: neural pathway and behavioural consequences
Biochem Soc Trans (2014) 42 (4): 878–881.
Pheromone-induced cell proliferation in the murine subventricular zone
Biochem Soc Trans (2014) 42 (4): 882–885.
Complementary roles of mouse lipocalins in chemical communication and immunity
Biochem Soc Trans (2014) 42 (4): 893–898.
Redox Regulation in Health and Disease: a Celebration of 50 Years of the Keilin Memorial Lecture
About the dangers, costs and benefits of living an aerobic lifestyle
Daniela Knoefler; Lars I.O. Leichert; Maike Thamsen; Claudia M. Cremers; Dana Reichmann; Michael J. Gray; Wei-Yun Wholey; Ursula Jakob
Biochem Soc Trans (2014) 42 (4): 917–921.
Thioredoxin as a putative biomarker and candidate target in age-related immune decline
Biochem Soc Trans (2014) 42 (4): 922–927.
Endothelial cell oxidative stress in diabetes: a key driver of cardiovascular complications?
Biochem Soc Trans (2014) 42 (4): 928–933.
Mitochondria and redox homoeostasis as chemotherapeutic targets
Biochem Soc Trans (2014) 42 (4): 939–944.
Regulation of the 2-oxoglutarate-dependent dioxygenases and implications for cancer
Biochem Soc Trans (2014) 42 (4): 945–951.
Mechanisms and physiological impact of the dual localization of mitochondrial intermembrane space proteins
Biochem Soc Trans (2014) 42 (4): 952–958.
Aberrant redox homoeostasis and mitochondrial dysfunction in Rett syndrome
Biochem Soc Trans (2014) 42 (4): 959–964.
Application of redox proteomics to skeletal muscle aging and exercise
Biochem Soc Trans (2014) 42 (4): 965–970.
Reassessing cellular glutathione homoeostasis: novel insights revealed by genetically encoded redox probes
Biochem Soc Trans (2014) 42 (4): 979–984.
Ultra-endurance exercise: unanswered questions in redox biology and immunology
Biochem Soc Trans (2014) 42 (4): 989–995.
The red blood cell: a new key player in cardiovascular homoeostasis? Focus on the nitric oxide pathway
Biochem Soc Trans (2014) 42 (4): 996–1000.
Hypercholesterolaemia-induced oxidative stress at the blood–brain barrier
Biochem Soc Trans (2014) 42 (4): 1001–1005.
The role of oxidative stress in the cardiovascular actions of particulate air pollution
Biochem Soc Trans (2014) 42 (4): 1006–1011.
Manganese superoxide dismutase in carcinogenesis: friend or foe?
Biochem Soc Trans (2014) 42 (4): 1012–1016.
Novel flavonoids as anti-cancer agents: mechanisms of action and promise for their potential application in breast cancer
Carlos Martinez-Perez; Carol Ward; Graeme Cook; Peter Mullen; Donald McPhail; David J. Harrison; Simon P. Langdon
Biochem Soc Trans (2014) 42 (4): 1017–1023.
Coenzyme A and Its Derivatives in Cellular Metabolism and Disease
Coenzyme A and its derivatives: renaissance of a textbook classic
Biochem Soc Trans (2014) 42 (4): 1025–1032.
Physiological roles of the pantothenate kinases
Lorraine E. Dansie; Stacy Reeves; Karen Miller; Stephen P. Zano; Matthew Frank; Caroline Pate; Jina Wang; Suzanne Jackowski
Biochem Soc Trans (2014) 42 (4): 1033–1036.
Protein acetylation as a means to regulate protein function in tune with metabolic state
Biochem Soc Trans (2014) 42 (4): 1037–1042.
Role of CoA and acetyl-CoA in regulating cardiac fatty acid and glucose oxidation
Biochem Soc Trans (2014) 42 (4): 1043–1051.
Chemical biology tools to study pantetheinases of the vanin family
Biochem Soc Trans (2014) 42 (4): 1052–1055.
Signalling functions of coenzyme A and its derivatives in mammalian cells
Biochem Soc Trans (2014) 42 (4): 1056–1062.
Alteration of the coenzyme A biosynthetic pathway in neurodegeneration with brain iron accumulation syndromes
Biochem Soc Trans (2014) 42 (4): 1069–1074.
Recent advances in targeting coenzyme A biosynthesis and utilization for antimicrobial drug development
Biochem Soc Trans (2014) 42 (4): 1080–1086.
Exploiting the coenzyme A biosynthesis pathway for the identification of new antimalarial agents: the case for pantothenamides
Biochem Soc Trans (2014) 42 (4): 1087–1093.
Role of the Vnn1 pantetheinase in tissue tolerance to stress
Biochem Soc Trans (2014) 42 (4): 1094–1100.
Intracellular redistribution of acetyl-CoA, the pivotal point in differential susceptibility of cholinergic neurons and glial cells to neurodegenerative signals
Andrzej Szutowicz; Hanna Bielarczyk; Anna Ronowska; Sylwia Gul-Hinc; Joanna Klimaszewska-Łata; Aleksandra Dyś; Marlena Zyśk; Tadeusz Pawełczyk
Biochem Soc Trans (2014) 42 (4): 1101–1106.
Methods for measuring CoA and CoA derivatives in biological samples
Biochem Soc Trans (2014) 42 (4): 1107–1111.
Deregulated coenzyme A, loss of metabolic flexibility and diabetes
Biochem Soc Trans (2014) 42 (4): 1118–1122.
Independent Meetings
RNA UK 2014
Mechanisms of transcriptional dysregulation in repeat expansion disorders
Biochem Soc Trans (2014) 42 (4): 1123–1128.
Regulation of miRNA strand selection: follow the leader?
Biochem Soc Trans (2014) 42 (4): 1135–1140.
Structural investigations of the RNA-binding properties of STAR proteins
Biochem Soc Trans (2014) 42 (4): 1141–1146.
Regulation of ELAV/Hu RNA-binding proteins by phosphorylation
Biochem Soc Trans (2014) 42 (4): 1147–1151.
Tra2 protein biology and mechanisms of splicing control
Andrew Best; Caroline Dalgliesh; Mahsa Kheirollahi-Kouhestani; Marina Danilenko; Ingrid Ehrmann; Alison Tyson-Capper; David J. Elliott
Biochem Soc Trans (2014) 42 (4): 1152–1158.
Conflict RNA modification, host–parasite co-evolution, and the origins of DNA and DNA-binding proteins
Biochem Soc Trans (2014) 42 (4): 1159–1167.
Emerging functions of alternative splicing coupled with nonsense-mediated decay
Biochem Soc Trans (2014) 42 (4): 1168–1173.
Human genetic variation and its effect on miRNA biogenesis, activity and function
Biochem Soc Trans (2014) 42 (4): 1184–1189.
Regulation of gene expression through production of unstable mRNA isoforms
Biochem Soc Trans (2014) 42 (4): 1196–1205.
Single-molecule fluorescence-based studies on the dynamics, assembly and catalytic mechanism of the spliceosome
Biochem Soc Trans (2014) 42 (4): 1211–1218.
Acute kidney injury: a paradigm for miRNA regulation of the cell cycle
Biochem Soc Trans (2014) 42 (4): 1219–1223.
Recent studies implicate the nucleolus as the major site of nuclear translation
Biochem Soc Trans (2014) 42 (4): 1224–1228.
Poly(A)-binding proteins are required for diverse biological processes in metazoans
Biochem Soc Trans (2014) 42 (4): 1229–1237.
eIF4E-binding proteins: new factors, new locations, new roles
Biochem Soc Trans (2014) 42 (4): 1238–1245.
Yeast mRNA localization: protein asymmetry, organelle localization and response to stress
Biochem Soc Trans (2014) 42 (4): 1256–1260.
