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August 2010
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ISSN 0300-5127
EISSN 1470-8752
Biochemical Society Awards
Keilin Memorial Lecture
AstraZeneca Award Lecture
Synchrotron radiation circular dichroism (SRCD) spectroscopy: an enhanced method for examining protein conformations and protein interactions
Biochem Soc Trans (2010) 38 (4): 861–873.
Biochemical Society Focused Meetings
Experimental Approaches to Protein–Protein Interactions
Interaction proteomics: characterization of protein complexes using tandem affinity purification–mass spectrometry
Biochem Soc Trans (2010) 38 (4): 883–887.
Calorimetry as a tool for understanding biomolecular interactions and an aid to drug design
Biochem Soc Trans (2010) 38 (4): 888–893.
Unravelling protein–protein interactions between complement factor H and C-reactive protein using a multidisciplinary strategy
Biochem Soc Trans (2010) 38 (4): 894–900.
Selection of soluble protein expression constructs: the experimental determination of protein domain boundaries
Biochem Soc Trans (2010) 38 (4): 908–913.
Single-molecule two-colour coincidence detection to probe biomolecular associations
Biochem Soc Trans (2010) 38 (4): 914–918.
High-throughput identification of transient extracellular protein interactions
Biochem Soc Trans (2010) 38 (4): 919–922.
Proteomic Complex Detection using Sedimentation (ProCoDeS): screening for proteins in stable complexes and their candidate interaction partners
Biochem Soc Trans (2010) 38 (4): 923–927.
The Biology of Tau and its Role in Tauopathies
Alzheimer's disease neurofibrillary degeneration: pivotal and multifactorial
Biochem Soc Trans (2010) 38 (4): 962–966.
From tau phosphorylation to tau aggregation: what about neuronal death?
Luc Buée; Laëtitia Troquier; Sylvie Burnouf; Karim Belarbi; Anneke Van der Jeugd; Tariq Ahmed; Francisco Fernandez-Gomez; Raphaelle Caillierez; Marie-Eve Grosjean; Séverine Begard; Bérangère Barbot; Dominique Demeyer; Hélène Obriot; Ingrid Brion; Valérie Buée-Scherrer; Claude-Alain Maurage; Detlef Balschun; Rudi D'Hooge; Malika Hamdane; David Blum; Nicolas Sergeant
Biochem Soc Trans (2010) 38 (4): 967–972.
The role of MSUT-2 in tau neurotoxicity: a target for neuroprotection in tauopathy?
Biochem Soc Trans (2010) 38 (4): 973–976.
Tau phosphorylation in hippocampus results in toxic gain-of-function
Biochem Soc Trans (2010) 38 (4): 977–980.
Phosphorylation differentiates tau-dependent neuronal toxicity and dysfunction
Biochem Soc Trans (2010) 38 (4): 981–987.
Deletion of murine tau gene increases tau aggregation in a human mutant tau transgenic mouse model
Kunie Ando; Karelle Leroy; Céline Heraud; Anna Kabova; Zehra Yilmaz; Michèle Authelet; Valèrie Suain; Robert De Decker; Jean-Pierre Brion
Biochem Soc Trans (2010) 38 (4): 1001–1005.
NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease
Isabelle Landrieu; Arnaud Leroy; Caroline Smet-Nocca; Isabelle Huvent; Laziza Amniai; Malika Hamdane; Nathalie Sibille; Luc Buée; Jean-Michel Wieruszeski; Guy Lippens
Biochem Soc Trans (2010) 38 (4): 1006–1011.
Links between ApoE, brain cholesterol metabolism, tau and amyloid β-peptide in patients with cognitive impairment
Biochem Soc Trans (2010) 38 (4): 1021–1025.
Revolutionizing Drug Discovery with Stem Cell Technology
Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening
Biochem Soc Trans (2010) 38 (4): 1037–1045.
High-content screening of small compounds on human embryonic stem cells
Biochem Soc Trans (2010) 38 (4): 1046–1050.
Human pluripotent stem cells in drug discovery and predictive toxicology
Biochem Soc Trans (2010) 38 (4): 1051–1057.
Identification and characterization of small-molecule ligands that maintain pluripotency of human embryonic stem cells
Peter Burton; David R. Adams; Achamma Abraham; Robert W. Allcock; Zhong Jiang; Angela McCahill; Jane Gilmour; John McAbney; Nicole M. Kane; George S. Baillie; Fergus R. McKenzie; Andrew H. Baker; Miles D. Houslay; Joanne C. Mountford; Graeme Milligan
Biochem Soc Trans (2010) 38 (4): 1058–1061.
The potential of small chemical functional groups for directing the differentiation of kidney stem cells
Patricia Murray; Krasimir Vasilev; Cristina Fuente Mora; Egon Ranghini; Hayeit Tensaout; Aleksandra Rak-Raszewska; Bettina Wilm; David Edgar; Robert D. Short; Simon E. Kenny
Biochem Soc Trans (2010) 38 (4): 1062–1066.
Imaging-based chemical screens using normal and glioma-derived neural stem cells
Davide Danovi; Anna Falk; Peter Humphreys; Richard Vickers; Jon Tinsley; Austin G. Smith; Steven M. Pollard
Biochem Soc Trans (2010) 38 (4): 1067–1071.
Developments in three-dimensional cell culture technology aimed at improving the accuracy of in vitro analyses
Biochem Soc Trans (2010) 38 (4): 1072–1075.
RNA UK 2010
Alternative polyadenylation of antisense RNAs and flowering time control
Biochem Soc Trans (2010) 38 (4): 1077–1081.
Secondary structure of U6 small nuclear RNA: implications for spliceosome assembly
Biochem Soc Trans (2010) 38 (4): 1099–1104.
The function of the NineTeen Complex (NTC) in regulating spliceosome conformations and fidelity during pre-mRNA splicing
Biochem Soc Trans (2010) 38 (4): 1110–1115.
The evolution of spliced leader trans-splicing in nematodes
Biochem Soc Trans (2010) 38 (4): 1125–1130.
Inhibition of translation initiation following glucose depletion in yeast facilitates a rationalization of mRNA content
Biochem Soc Trans (2010) 38 (4): 1131–1136.
