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October 2006
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ISSN 0300-5127
EISSN 1470-8752
In this Issue
Biochemical Society Awards
Novartis Medal Lecture
Colworth Medal Lecture
Morton Lecture
Biochemical Society Award Lecture
The mystery of intracellular developmental programmes and timers
Biochem Soc Trans (2006) 34 (5): 663–670.
BioScience2006
Co-ordination of Cellular Processes
The role of myosin Va in secretory granule trafficking and exocytosis
Biochem Soc Trans (2006) 34 (5): 671–674.
Rapid three-dimensional imaging of individual insulin release events by Nipkow disc confocal microscopy
Biochem Soc Trans (2006) 34 (5): 675–678.
Fluorescence lifetime imaging microscopy (FLIM) to quantify protein–protein interactions inside cells
Biochem Soc Trans (2006) 34 (5): 679–682.
Interactions between Rabs, tethers, SNAREs and their regulators in exocytosis
Biochem Soc Trans (2006) 34 (5): 683–686.
The molecular mechanisms of the mammalian exocyst complex in exocytosis
Biochem Soc Trans (2006) 34 (5): 687–690.
Rab27 and its effectors in secretory granule exocytosis: a novel docking machinery composed of a Rab27·effector complex
Biochem Soc Trans (2006) 34 (5): 691–695.
Mechanisms controlling the expression of the components of the exocytotic apparatus under physiological and pathological conditions
Biochem Soc Trans (2006) 34 (5): 696–700.
The Kaposi's sarcoma-associated herpesvirus ORF57 protein: a pleurotropic regulator of gene expression
Biochem Soc Trans (2006) 34 (5): 705–710.
Mitotic spindle morphogenesis: Ran on the microtubule cytoskeleton and beyond
Biochem Soc Trans (2006) 34 (5): 716–721.
Phosphoinositide 3-kinase signalling and FoxO transcription factors in rheumatoid arthritis
Biochem Soc Trans (2006) 34 (5): 727–730.
Information Processing and Molecular Signalling
p62 mutations, ubiquitin recognition and Paget's disease of bone
Biochem Soc Trans (2006) 34 (5): 735–737.
Molecular misreading: the occurrence of frameshift proteins in different diseases
Biochem Soc Trans (2006) 34 (5): 738–742.
The aggravating role of the ubiquitin–proteasome system in neurodegenerative disease
Biochem Soc Trans (2006) 34 (5): 743–745.
Control of growth factor receptor dynamics by reversible ubiquitination
Biochem Soc Trans (2006) 34 (5): 754–756.
The role of ubiquitin in neurotrophin receptor signalling and sorting
Biochem Soc Trans (2006) 34 (5): 757–760.
Reversible ubiquitination regulates the Smad/TGF-β signalling pathway
Biochem Soc Trans (2006) 34 (5): 761–763.
De-ubiquitinating enzymes: intracellular signalling and disease
Biochem Soc Trans (2006) 34 (5): 764–769.
The G-protein-coupled receptor 40 family (GPR40–GPR43) and its role in nutrient sensing
Biochem Soc Trans (2006) 34 (5): 770–773.
Nutrient regulation of pancreatic β-cell function in diabetes: problems and potential solutions
Biochem Soc Trans (2006) 34 (5): 774–778.
Maternal nutrition during pregnancy and health of the offspring
Biochem Soc Trans (2006) 34 (5): 779–782.
Hsp90 chaperone control over transcriptional regulation by the yeast Slt2(Mpk1)p and human ERK5 mitogen-activated protein kinases (MAPKs)
Biochem Soc Trans (2006) 34 (5): 783–785.
Regulation of purine nucleotide biosynthesis: in yeast and beyond
Biochem Soc Trans (2006) 34 (5): 786–790.
Regulation by Per-Arnt-Sim (PAS) kinase of pancreatic duodenal homeobox-1 nuclear import in pancreatic β-cells
Biochem Soc Trans (2006) 34 (5): 791–793.
Phosphorylation of Zn(II)2Cys6 proteins: a cause or effect of transcriptional activation?
Biochem Soc Trans (2006) 34 (5): 794–797.
Mechanisms regulating energy metabolism by adiponectin in obesity and diabetes
Biochem Soc Trans (2006) 34 (5): 798–801.
Nicotinamide nucleotide transhydrogenase: a link between insulin secretion, glucose metabolism and oxidative stress
Biochem Soc Trans (2006) 34 (5): 806–810.
The importance of redox shuttles to pancreatic β-cell energy metabolism and function
Biochem Soc Trans (2006) 34 (5): 811–814.
Molecular architecture of the pyruvate dehydrogenase complex: bridging the gap
Biochem Soc Trans (2006) 34 (5): 815–818.
Mitochondrial diabetes and its lessons for common Type 2 diabetes
Biochem Soc Trans (2006) 34 (5): 819–823.
Mitochondrial damages and the regulation of insulin secretion
Biochem Soc Trans (2006) 34 (5): 824–827.
Spatio-temporal regulation of mitogen-activated protein kinase (MAPK) signalling by protein phosphatases
Biochem Soc Trans (2006) 34 (5): 842–845.
The GAP1 family of GTPase-activating proteins: spatial and temporal regulators of small GTPase signalling
Biochem Soc Trans (2006) 34 (5): 846–850.
Regulation of RalA GTPase by phosphatidylinositol 3-kinase as visualized by FRET probes
Biochem Soc Trans (2006) 34 (5): 851–854.
The lipid second messenger diacylglycerol as a negative regulator of Rac signalling
Biochem Soc Trans (2006) 34 (5): 855–857.
Ion Channels: Communication across Membranes
The role of GABAA receptor biogenesis, structure and function in epilepsy
Biochem Soc Trans (2006) 34 (5): 863–867.
Do polymorphisms in the human 5-HT3 genes contribute to pathological phenotypes?
Biochem Soc Trans (2006) 34 (5): 872–876.
Novel structural determinants of single-channel conductance in nicotinic acetylcholine and 5-hydroxytryptamine type-3 receptors
Biochem Soc Trans (2006) 34 (5): 882–886.
The structural biology of voltage-gated calcium channel function and regulation
Biochem Soc Trans (2006) 34 (5): 887–893.
Do voltage-gated calcium channel α2δ subunits require proteolytic processing into α2 and δ to be functional?
Biochem Soc Trans (2006) 34 (5): 894–898.
Role of voltage-gated L-type Ca2+ channel isoforms for brain function
J. Striessnig; A. Koschak; M.J. Sinnegger-Brauns; A. Hetzenauer; N.K. Nguyen; P. Busquet; G. Pelster; N. Singewald
Biochem Soc Trans (2006) 34 (5): 903–909.
Role of ryanodine receptor mutations in cardiac pathology: more questions than answers?
Biochem Soc Trans (2006) 34 (5): 913–918.
Redox regulation of the ryanodine receptor/calcium release channel
Biochem Soc Trans (2006) 34 (5): 919–921.
NAADP, a new intracellular messenger that mobilizes Ca2+ from acidic stores
Biochem Soc Trans (2006) 34 (5): 922–926.
Kainate receptor-interacting proteins and membrane trafficking
Biochem Soc Trans (2006) 34 (5): 927–930.
Molecular mechanisms for regulation of AMPAR trafficking by PICK1
Biochem Soc Trans (2006) 34 (5): 931–935.
Molecular characterization of the metabotropic glutamate receptor family in Caenorhabditis elegans
Biochem Soc Trans (2006) 34 (5): 942–948.
Proteins: Structure and Function
Interactions between nitric oxide, oxygen, reactive oxygen species and reactive nitrogen species
Biochem Soc Trans (2006) 34 (5): 953–956.
Linking proximal and downstream signalling events in hepatic ischaemia/reperfusion injury
Biochem Soc Trans (2006) 34 (5): 957–959.
Redox signalling involving NADPH oxidase-derived reactive oxygen species
Biochem Soc Trans (2006) 34 (5): 960–964.
Superoxide, peroxynitrite and oxidative/nitrative stress in inflammation
Biochem Soc Trans (2006) 34 (5): 965–970.
Folding and unfolding for binding: large-scale protein dynamics in protein–protein interactions
Biochem Soc Trans (2006) 34 (5): 971–974.
Blinking fluorophores: what do they tell us about protein dynamics?
Biochem Soc Trans (2006) 34 (5): 979–982.
Inhibitors of the catalytic domain of mitochondrial ATP synthase
Biochem Soc Trans (2006) 34 (5): 989–992.