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October 2005
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ISSN 0300-5127
EISSN 1470-8752
Biochemical Society Awards
Novartis Medal Lecture
BioScience2005
Mechanistic and Functional Studies of Proteins
Simulation studies of the interactions between membrane proteins and detergents
Biochem Soc Trans (2005) 33 (5): 910–912.
Molecular simulations and lipid–protein interactions: potassium channels and other membrane proteins
Biochem Soc Trans (2005) 33 (5): 916–920.
Binding sites of lipophilic quinone and quinone analogue inhibitors in the cytochrome b6f complex of oxygenic photosynthesis
Biochem Soc Trans (2005) 33 (5): 921–923.
Quantification of the effects of melittin on liposome structure
Biochem Soc Trans (2005) 33 (5): 931–933.
Synchronizing the Neurospora crassa circadian clock with the rhythmic environment
Biochem Soc Trans (2005) 33 (5): 949–952.
Degradation of the Neurospora circadian clock protein FREQUENCY through the ubiquitin–proteasome pathway
Biochem Soc Trans (2005) 33 (5): 953–956.
The extraordinary mitochondrion and unusual citric acid cycle in Trypanosoma brucei
Biochem Soc Trans (2005) 33 (5): 967–971.
Implications of a genomic search for autophagy-related genes in trypanosomatids
Biochem Soc Trans (2005) 33 (5): 972–974.
Plasmodium falciparum possesses organelle-specific α-keto acid dehydrogenase complexes and lipoylation pathways
Biochem Soc Trans (2005) 33 (5): 977–980.
The myo-inositol-1-phosphate synthase gene is essential in Trypanosoma brucei
Biochem Soc Trans (2005) 33 (5): 983–985.
What the genome sequence is revealing about trypanosome antigenic variation
J.D. Barry; L. Marcello; L.J. Morrison; A.F. Read; K. Lythgoe; N. Jones; M. Carrington; G. Blandin; U. Böhme; E. Caler; C. Hertz-Fowler; H. Renauld; N. El-Sayed; M. Berriman
Biochem Soc Trans (2005) 33 (5): 986–989.
A molecular understanding of the catalytic cycle of the nucleotide-binding domain of the ABC transporter HlyB
Biochem Soc Trans (2005) 33 (5): 990–995.
Crystallographic and single-particle analyses of native- and nucleotide-bound forms of the cystic fibrosis transmembrane conductance regulator (CFTR) protein
Biochem Soc Trans (2005) 33 (5): 996–999.
Similarities between ATP-dependent and ion-coupled multidrug transporters
Biochem Soc Trans (2005) 33 (5): 1008–1011.
Do protein–lipid interactions determine the recognition of transmembrane helices at the ER translocon?
Biochem Soc Trans (2005) 33 (5): 1012–1015.
The complexity of pathways for protein import into thylakoids: it's not easy being green
Biochem Soc Trans (2005) 33 (5): 1024–1027.
Proteins in Disease
Insulin and cognitive function in humans: experimental data and therapeutic considerations
Biochem Soc Trans (2005) 33 (5): 1037–1040.
Increased risk of Alzheimer's disease in Type II diabetes: insulin resistance of the brain or insulin-induced amyloid pathology?
Biochem Soc Trans (2005) 33 (5): 1041–1044.
Adipose tissue function in the insulin-resistance syndrome
Biochem Soc Trans (2005) 33 (5): 1045–1048.
Mouse models of PPAR-γ deficiency: dissecting PPAR-γ's role in metabolic homoeostasis
Biochem Soc Trans (2005) 33 (5): 1053–1058.
Role of malonyl-CoA in the hypothalamic control of food intake and energy expenditure
Biochem Soc Trans (2005) 33 (5): 1063–1067.
Diet-induced obesity in the Sprague–Dawley rat: dietary manipulations and their effect on hypothalamic neuropeptide energy balance systems
Biochem Soc Trans (2005) 33 (5): 1068–1072.
Diseases of adipose tissue: genetic and acquired lipodystrophies
Biochem Soc Trans (2005) 33 (5): 1073–1077.
Protein aggregation, metals and oxidative stress in neurodegenerative diseases
Biochem Soc Trans (2005) 33 (5): 1082–1086.
The role of cell-derived oligomers of Aβ in Alzheimer's disease and avenues for therapeutic intervention
D.M. Walsh; I. Klyubin; G.M. Shankar; M. Townsend; J.V. Fadeeva; V. Betts; M.B. Podlisny; J.P. Cleary; K.H. Ashe; M.J. Rowan; D.J. Selkoe
Biochem Soc Trans (2005) 33 (5): 1087–1090.
Expression and activity of β-site amyloid precursor protein cleaving enzyme in Alzheimer's disease
Biochem Soc Trans (2005) 33 (5): 1096–1100.
Aβ-degrading enzymes: modulators of Alzheimer's disease pathogenesis and targets for therapeutic intervention
Biochem Soc Trans (2005) 33 (5): 1101–1105.
α-Synuclein aggregation in neurodegenerative diseases and its inhibition as a potential therapeutic strategy
Biochem Soc Trans (2005) 33 (5): 1106–1110.
Structure and neurotoxicity of novel amyloids derived from the BRI gene
Biochem Soc Trans (2005) 33 (5): 1111–1112.
Studies of the aggregation of an amyloidogenic α-synuclein peptide fragment
Biochem Soc Trans (2005) 33 (5): 1113–1115.
Novel heparan sulphate analogues: inhibition of β-secretase cleavage of amyloid precursor protein
Biochem Soc Trans (2005) 33 (5): 1116–1118.
Research Colloquia
Reactive oxygen species (ROS)-mediated β-cleavage of the prion protein in the mechanism of the cellular response to oxidative stress
Biochem Soc Trans (2005) 33 (5): 1123–1125.
Inhibition of pro-inflammatory cytokine receptor signalling by cAMP in vascular endothelial cells
Biochem Soc Trans (2005) 33 (5): 1126–1128.
Compartmentation of G-protein-coupled receptors and their signalling components in lipid rafts and caveolae
Biochem Soc Trans (2005) 33 (5): 1131–1134.
Independent Meetings
Seventh Yeast Lipid Conference
The contributions of biosynthesis and acyl chain remodelling to the molecular species profile of phosphatidylcholine in yeast
Biochem Soc Trans (2005) 33 (5): 1146–1149.
In Saccharomyces cerevisiae, impaired PRPP synthesis is accompanied by valproate and Li+ sensitivity
Biochem Soc Trans (2005) 33 (5): 1154–1157.
Deficiency in mitochondrial anionic phospholipid synthesis impairs cell wall biogenesis
Biochem Soc Trans (2005) 33 (5): 1158–1161.
Mitochondrial fatty acid synthesis and maintenance of respiratory competent mitochondria in yeast
Biochem Soc Trans (2005) 33 (5): 1162–1165.
Using genomic and lipidomic strategies to investigate sphingolipid function in the yeast heat-stress response
Biochem Soc Trans (2005) 33 (5): 1166–1169.
Signalling functions for sphingolipid long-chain bases in Saccharomyces cerevisiae
Biochem Soc Trans (2005) 33 (5): 1170–1173.
Formation and mobilization of neutral lipids in the yeast Saccharomyces cerevisiae
Biochem Soc Trans (2005) 33 (5): 1174–1177.
Saccharomyces cerevisiae, a model to study sterol uptake and transport in eukaryotes
Biochem Soc Trans (2005) 33 (5): 1186–1188.
Enzyme redesign and interactions of substrate analogues with sterol methyltransferase to understand phytosterol diversity, reaction mechanism and the nature of the active site
Biochem Soc Trans (2005) 33 (5): 1189–1196.
Single amino acid exchanges in FAD-binding domains of squalene epoxidase of Saccharomyces cerevisiae lead to either loss of functionality or terbinafine sensitivity
Biochem Soc Trans (2005) 33 (5): 1197–1201.
Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies
Biochem Soc Trans (2005) 33 (5): 1202–1205.
Two mutants selectively resistant to polyenes reveal distinct mechanisms of antifungal activity by nystatin and amphotericin B
Biochem Soc Trans (2005) 33 (5): 1206–1209.
Membrane raft lipid constituents affect drug susceptibilities of Candida albicans
Biochem Soc Trans (2005) 33 (5): 1219–1223.
