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August 2005
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ISSN 0300-5127
EISSN 1470-8752
In this Issue
Biochemical Society Focused Meetings
Molecular Mechanisms of Neurodegeneration
‘Nature-inspired’ drug–protein complexes as inhibitors of Aβ aggregation
Biochem Soc Trans (2005) 33 (4): 543–547.
The production of hydrogen peroxide during early-stage protein aggregation: a common pathological mechanism in different neurodegenerative diseases?
Biochem Soc Trans (2005) 33 (4): 548–550.
Disease modifying strategies for the treatment of Alzheimer's disease targeted at modulating levels of the β-amyloid peptide
Biochem Soc Trans (2005) 33 (4): 553–558.
Synaptic plasticity disruption by amyloid β protein: modulation by potential Alzheimer's disease modifying therapies
Biochem Soc Trans (2005) 33 (4): 563–567.
Evidence that vitamin D3 reverses age-related inflammatory changes in the rat hippocampus
Biochem Soc Trans (2005) 33 (4): 573–577.
Evidence suggesting that Homo neanderthalensis contributed the H2 MAPT haplotype to Homo sapiens
Biochem Soc Trans (2005) 33 (4): 582–585.
Pathophysiology, pleotrophy and paradigm shifts: genetic lessons from Parkinson's disease
Biochem Soc Trans (2005) 33 (4): 586–590.
Localization and Activation of Ras-like GTPases
Insights into biological functions across species: examining the role of Rab proteins in YIP1 family function
Biochem Soc Trans (2005) 33 (4): 614–618.
Membrane curvature and the control of GTP hydrolysis in Arf1 during COPI vesicle formation
Biochem Soc Trans (2005) 33 (4): 619–622.
RhoGDI-3, a promising system to investigate the regulatory function of rhoGDIs: uncoupling of inhibitory and shuttling functions of rhoGDIs
Biochem Soc Trans (2005) 33 (4): 623–626.
Mechanism and role of localized activation of Rho-family GTPases in growth factor-stimulated fibroblasts and neuronal cells
Biochem Soc Trans (2005) 33 (4): 631–634.
On the action of Brefeldin A on Sec7-stimulated membrane-recruitment and GDP/GTP exchange of Arf proteins
Biochem Soc Trans (2005) 33 (4): 635–638.
Use of the Ras binding domain of c-Raf for biochemical and live-cell analysis of Ras activation
Biochem Soc Trans (2005) 33 (4): 662–663.
The Molecular Biology of Colorectal Cancer
Prospects in NSAID-derived chemoprevention of colorectal cancer
S. Chell; H.A. Patsos; D. Qualtrough; A.M. H-Zadeh; D.J. Hicks; A. Kaidi; I.R. Witherden; A.C. Williams; C. Paraskeva
Biochem Soc Trans (2005) 33 (4): 667–671.
The role of the retinoblastoma protein (Rb) in the nuclear localization of BAG-1: implications for colorectal tumour cell survival
N.K. Clemo; N.J. Arhel; J.D. Barnes; J. Baker; M. Moorghen; G.K. Packham; C. Paraskeva; A.C. Williams
Biochem Soc Trans (2005) 33 (4): 676–678.
Functional consequences of DNA mismatch repair missense mutations in murine models and their impact on cancer predisposition
Biochem Soc Trans (2005) 33 (4): 689–693.
Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal regulation
Biochem Soc Trans (2005) 33 (4): 694–697.
Pro-inflammatory mediator leukotriene D4 induces transcriptional activity of potentially oncogenic genes
Biochem Soc Trans (2005) 33 (4): 698–700.
Cannabinoids and cancer: potential for colorectal cancer therapy
Biochem Soc Trans (2005) 33 (4): 712–714.
DNA damage hypersensitivity in cells lacking BRCA2: a review of in vitro and in vivo data
Biochem Soc Trans (2005) 33 (4): 715–717.
Phenotype associated with recessively inherited mutations in DNA mismatch repair (MMR) genes
Biochem Soc Trans (2005) 33 (4): 718–720.
Action of a library of O-glycosylation inhibitors on the growth of human colorectal cancer cells in culture
Biochem Soc Trans (2005) 33 (4): 721–723.
DNA mismatch repair status may influence anti-neoplastic effects of butyrate
Biochem Soc Trans (2005) 33 (4): 728–729.
DMBT1 expression and glycosylation during the adenoma–carcinoma sequence in colorectal cancer
Biochem Soc Trans (2005) 33 (4): 730–732.
The importance of colonic butyrate transport to the regulation of genes associated with colonic tissue homoeostasis
Biochem Soc Trans (2005) 33 (4): 733–735.
Independent Meetings
Coenzymology: the biochemistry of vitamin biogenesis and cofactor-containing enzymes
Flavocytochrome P450 BM3: an update on structure and mechanism of a biotechnologically important enzyme
A.J. Warman; O. Roitel; R. Neeli; H.M. Girvan; H.E. Seward; S.A. Murray; K.J. McLean; M.G. Joyce; H. Toogood; R.A. Holt; D. Leys; N.S. Scrutton; A.W. Munro
Biochem Soc Trans (2005) 33 (4): 747–753.
Flavoenzyme catalysed oxidation of amines: roles for flavin and protein-based radicals
S.E. Rigby; J. Basran; J.P. Combe; A.W. Mohsen; H. Toogood; A. van Thiel; M.J. Sutcliffe; D. Leys; A.W. Munro; N.S. Scrutton
Biochem Soc Trans (2005) 33 (4): 754–757.
Mechanistic and inhibition studies of chorismate-utilizing enzymes
Biochem Soc Trans (2005) 33 (4): 763–766.
Biophysical tools to monitor enzyme–ligand interactions of enzymes involved in vitamin biosynthesis
Biochem Soc Trans (2005) 33 (4): 767–771.
Crystal structure of DMGO provides a prototype for a new tetrahydrofolate-binding fold
Biochem Soc Trans (2005) 33 (4): 776–779.
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin
Biochem Soc Trans (2005) 33 (4): 780–784.
Biodiversity of cytochrome P450 redox systems
K.J. McLean; M. Sabri; K.R. Marshall; R.J. Lawson; D.G. Lewis; D. Clift; P.R. Balding; A.J. Dunford; A.J. Warman; J.P. McVey; A.-M. Quinn; M.J. Sutcliffe; N.S. Scrutton; A.W. Munro
Biochem Soc Trans (2005) 33 (4): 796–801.
Inhibition of 7,8-diaminopelargonic acid aminotransferase by amiclenomycin and analogues
Biochem Soc Trans (2005) 33 (4): 802–805.
Anaerobic synthesis of vitamin B12: characterization of the early steps in the pathway
S. Frank; A.A. Brindley; E. Deery; P. Heathcote; A.D. Lawrence; H.K. Leech; R.W. Pickersgill; M.J. Warren
Biochem Soc Trans (2005) 33 (4): 811–814.
Aerobic synthesis of vitamin B12: ring contraction and cobalt chelation
Biochem Soc Trans (2005) 33 (4): 815–819.
Mechanisms of Bioenergetic Membrane Proteins: Structures and Beyond
Is a third proton-conducting pathway operative in bacterial cytochrome c oxidase?
Biochem Soc Trans (2005) 33 (4): 829–831.
Ion translocation by the Escherichia coli NADH:ubiquinone oxidoreductase (complex I)
Biochem Soc Trans (2005) 33 (4): 836–839.
Structure–function relationships in mitochondrial complex I of the strictly aerobic yeast Yarrowia lipolytica
Biochem Soc Trans (2005) 33 (4): 840–844.
Ubiquinone reduction in the photosynthetic reaction centre of Rhodobacter sphaeroides: interplay between electron transfer, proton binding and flips of the quinone ring
Biochem Soc Trans (2005) 33 (4): 845–850.
Rewiring photosynthesis: engineering wrong-way electron transfer in the purple bacterial reaction centre
Biochem Soc Trans (2005) 33 (4): 851–857.
Role of electron-transfer quenching of chlorophyll fluorescence by carotenoids in non-photochemical quenching of green plants
Biochem Soc Trans (2005) 33 (4): 858–862.
Active membrane transport and receptor proteins from bacteria
M. Saidijam; K.E. Bettaney; G. Szakonyi; G. Psakis; K. Shibayama; S. Suzuki; J.L. Clough; V. Blessie; A. Abu-bakr; S. Baumberg; J. Meuller; C.K. Hoyle; S.L. Palmer; P. Butaye; K. Walravens; S.G. Patching; J. O'Reilly; N.G. Rutherford; R.M. Bill; D.I. Roper; M.K. Phillips-Jones; P.J.F. Henderson
Biochem Soc Trans (2005) 33 (4): 867–872.
NMR and fluorescence spectroscopy approaches to secondary and primary active multidrug efflux pumps
Biochem Soc Trans (2005) 33 (4): 873–877.
Subunit movement in individual H+-ATP synthases during ATP synthesis and hydrolysis revealed by fluorescence resonance energy transfer
Biochem Soc Trans (2005) 33 (4): 878–882.
Structural features and nucleotide-binding capability of the C subunit are integral to the regulation of the eukaryotic V1Vo ATPases
Biochem Soc Trans (2005) 33 (4): 883–885.
