Biochemical Society Transactions

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676th Meeting

Antibodies: a paradigm for the evolution of molecular recognition

Michael Neuberger

Biochem Soc Trans (2002) 30 (3): A47.

View Articletitled, Antibodies: a paradigm for the evolution of molecular recognition

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Tetrapyrroles: their Birth, Life and Death

Structure and function of glutamyl-tRNA reductase involved in 5-aminolevulinic acid formation

J. Moser; W.-D. Schubert; D. Heinz; D. Jahn

Biochem Soc Trans (2002) 30 (3): A47.

View Articletitled, Structure and function of glutamyl-tRNA reductase involved in 5-aminolevulinic acid formation

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Mutants, metals and mechanism of 5-aminolaevulinic acid dehydratase

P. M. Shoolingin-Jordan

Biochem Soc Trans (2002) 30 (3): A47.

View Articletitled, Mutants, metals and mechanism of 5-aminolaevulinic acid dehydratase

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The terminal steps of heme biosynthesis

H. A. Dailey

Biochem Soc Trans (2002) 30 (3): A47.

View Articletitled, The terminal steps of heme biosynthesis

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Structural diversity in metal ion chelation, and the structure of uro'gen III synthase

H. L. Schubert; E. Raux; M. A. A. Mathews; J. D. Phillips; K. S. Wilson; C. P. Hill; M. J. Warren

Biochem Soc Trans (2002) 30 (3): A48.

View Articletitled, Structural diversity in metal ion chelation, and the structure of uro'gen III synthase

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The biochemistry and enzymology of chlorophyll biosynthesis

C. N. Hunter

Biochem Soc Trans (2002) 30 (3): A48.

View Articletitled, The biochemistry and enzymology of chlorophyll biosynthesis

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Making light of it: the role of plant heme oxygenases in phytochrome chromophore synthesis

Matthew J. Terry

Biochem Soc Trans (2002) 30 (3): A48.

View Articletitled, Making light of it: the role of plant heme oxygenases in phytochrome chromophore synthesis

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Two enzymes for oxygen-dependent and independent decarboxylation of coproporphyrinogen III during bacterial tetrapyrrole biosynthesis

G. Layer; E. Mahlitz; D. Breckau; D. Jahn

Biochem Soc Trans (2002) 30 (3): A48.

View Articletitled, Two enzymes for oxygen-dependent and independent decarboxylation of coproporphyrinogen III during bacterial tetrapyrrole biosynthesis

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An investigation into the mechanism of SirB from Bacillus megaterium - a Sirohydrochlorin ferrochelatase

H. K. Leech; E. Raux-Deery; M. J. Warren

Biochem Soc Trans (2002) 30 (3): A49.

View Articletitled, An investigation into the mechanism of SirB from Bacillus megaterium - a Sirohydrochlorin ferrochelatase

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How Nature Sunthesizes Vitamin B₁₂. A Survey of the Last Four Billion Years

A. I. Scott

Biochem Soc Trans (2002) 30 (3): A49.

View Articletitled, How Nature Sunthesizes Vitamin B12. A Survey of the Last Four Billion Years

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Radical journeys catalyzed by B12-dependent methylmalonyl-CoA mutase

Ruma Banerjee

Biochem Soc Trans (2002) 30 (3): A49.

View Articletitled, Radical journeys catalyzed by B12-dependent methylmalonyl-CoA mutase

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Unraveling chlorophyll catabolism in higher plants

Bernhard Kraeutler

Biochem Soc Trans (2002) 30 (3): A49.

View Articletitled, Unraveling chlorophyll catabolism in higher plants

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Haem degradation in animals and plants

Timothy J. Mantle

Biochem Soc Trans (2002) 30 (3): A50.

View Articletitled, Haem degradation in animals and plants

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Cytochrome c maturation: a complex pathway for a simple task?

L. Thöny-Meyer

Biochem Soc Trans (2002) 30 (3): A50.

View Articletitled, Cytochrome c maturation: a complex pathway for a simple task?

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Structure of an unusual haemoprotein involved in thiosulfate oxidation

V. Bamford; T. Rasmussen; C. Appia-Ayme; P. J. Little; M. R. Cheesman; A. M. Hemmings; B. C. Berks

Biochem Soc Trans (2002) 30 (3): A50.

View Articletitled, Structure of an unusual haemoprotein involved in thiosulfate oxidation

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The coupling of ATP hydrolysis to metal ion insertion into porphyrins by magnesium chelatase

J. D. Reid; C. N. Hunter

Biochem Soc Trans (2002) 30 (3): A50.

View Articletitled, The coupling of ATP hydrolysis to metal ion insertion into porphyrins by magnesium chelatase

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Cobalamin (Vitamin B₁₂) Biosynthesis in Rhodobacter capsulatus.

H. M. McGoldrick

Biochem Soc Trans (2002) 30 (3): A51.

View Articletitled, Cobalamin (Vitamin B12) Biosynthesis in Rhodobacter capsulatus.

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Bacterial cytochrome c nitrite reductase: three-dimensional structure and spectroscopy of the multiheme enzyme

P. M. H. Kroneck

Biochem Soc Trans (2002) 30 (3): A51.

View Articletitled, Bacterial cytochrome c nitrite reductase: three-dimensional structure and spectroscopy of the multiheme enzyme

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Structure and function of the nickel tetrapyrrole F430 in methanogenic archaea

Rudolf K. Thauer

Biochem Soc Trans (2002) 30 (3): A51.

View Articletitled, Structure and function of the nickel tetrapyrrole F430 in methanogenic archaea

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A universal mechanism for fumarate reduction

Graeme A. Reid; Christopher G. Mowat; Caroline S. Miles; Kate Pankhurst; Malcolm D. Walkinshaw; Stephen K. Chapman

Biochem Soc Trans (2002) 30 (3): A51.

View Articletitled, A universal mechanism for fumarate reduction

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The resuscitation of two diheme respiratory enzymes

Nicholas J. Watmough

Biochem Soc Trans (2002) 30 (3): A52.

View Articletitled, The resuscitation of two diheme respiratory enzymes

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Crystal structure of formate dehydrogenase-N from E. coli

S. Iwata; M. Jormakka; S. Törnroth; B. Byrne

Biochem Soc Trans (2002) 30 (3): A52.

View Articletitled, Crystal structure of formate dehydrogenase-N from E. coli

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The structure and function of purple bacterial antenna complexes

R. J. Cogdell

Biochem Soc Trans (2002) 30 (3): A52.

View Articletitled, The structure and function of purple bacterial antenna complexes

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Spectroscopic characterisation of Cytochrome cbb3 oxidase from Pseudomonas stutzeri

R. S. Pitcher; M. R. Cheesman; T. Brittain; N. J. Watmough

Biochem Soc Trans (2002) 30 (3): A52.

View Articletitled, Spectroscopic characterisation of Cytochrome cbb3 oxidase from Pseudomonas stutzeri

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The role of membrane bound tetraheme CymA in the anaerobic respiration of Shewanella oneidensis MR-1

C. Schwalb; S. K. Chapman; G. A. Reid

Biochem Soc Trans (2002) 30 (3): A53.

View Articletitled, The role of membrane bound tetraheme CymA in the anaerobic respiration of Shewanella oneidensis MR-1

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The denitrification pathway of the hyperthermophile Pyrobaculum aerophilum

S. de Vries; I. Schroeder

Biochem Soc Trans (2002) 30 (3): A53.

View Articletitled, The denitrification pathway of the hyperthermophile Pyrobaculum aerophilum

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Amyloidogenic Proteins Involved in Neurodegeneration and Therapeutic Implications

The neuropatholgy of Alzheimer's disease

N. J. Cairns

Biochem Soc Trans (2002) 30 (3): A53.

View Articletitled, The neuropatholgy of Alzheimer's disease

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Protein misfolding and its links with human disease

C. M. Dobson

Biochem Soc Trans (2002) 30 (3): A53.

View Articletitled, Protein misfolding and its links with human disease

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Three-dimensional structure of amyloid fibrils

Louise C. Serpell; Sumner Makin

Biochem Soc Trans (2002) 30 (3): A54.

View Articletitled, Three-dimensional structure of amyloid fibrils

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Cholesterol and Alzheimer's disease

B. Wolozin

Biochem Soc Trans (2002) 30 (3): A54.

View Articletitled, Cholesterol and Alzheimer's disease

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Memapsin 2 (β-secretase) as a therapeutic target

L. Hong; R. Turner; G. Koelsch; A. K. Ghosh; J. Tang

Biochem Soc Trans (2002) 30 (3): A54.

View Articletitled, Memapsin 2 (β-secretase) as a therapeutic target

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γ-Secretase inhibition

D. Beher; M. S. Shearman

Biochem Soc Trans (2002) 30 (3): A54.

View Articletitled, γ-Secretase inhibition

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Transgenic models of Alzheimer's disease: behavioural studies and the prospects of therapeutic immunization

R. G. M. Morris

Biochem Soc Trans (2002) 30 (3): A55.

View Articletitled, Transgenic models of Alzheimer's disease: behavioural studies and the prospects of therapeutic immunization

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Inhibition of toxicity and protofibril formation in the β-amyloid peptide β(25–35) using N-Methylated derivatives

A. J. Doig; E. Hughes; R. M. Burke; T. J. Su; R. K. Heenan; J. Lu

Biochem Soc Trans (2002) 30 (3): A55.

View Articletitled, Inhibition of toxicity and protofibril formation in the β-amyloid peptide β(25–35) using N-Methylated derivatives

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Amyloid fibril formation by human stefin B; influence of solvent composition, trifluoroethanol and temperature

E. Zerovnik

Biochem Soc Trans (2002) 30 (3): A55.

View Articletitled, Amyloid fibril formation by human stefin B; influence of solvent composition, trifluoroethanol and temperature

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Polyglutamine conformation in GST-polyglutamine fusion proteins

L. Masino; A. Pastore

Biochem Soc Trans (2002) 30 (3): A55.

View Articletitled, Polyglutamine conformation in GST-polyglutamine fusion proteins

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Cell-derived Aβ oligomers: production, activity and inhibition

D. M. Walsh; I. Kylubin; J. V. Fadeeva; M. J. Rowan; D. J. Selkoe

Biochem Soc Trans (2002) 30 (3): A56.

View Articletitled, Cell-derived Aβ oligomers: production, activity and inhibition

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Properties of neurotoxic peptides related to the BRI gene

Brian Austen; Omar El-Agnaf; Sid Nagala; Bhroma Patel; Nicola Gunasekera

Biochem Soc Trans (2002) 30 (3): A56.

View Articletitled, Properties of neurotoxic peptides related to the BRI gene

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Oligomerisation and toxicity of alpha-synuclein

Omar M. A. El-Agnaf

Biochem Soc Trans (2002) 30 (3): A56.

View Articletitled, Oligomerisation and toxicity of alpha-synuclein

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Interactions between prion protein isoforms

B. Caughey

Biochem Soc Trans (2002) 30 (3): A56.

View Articletitled, Interactions between prion protein isoforms

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Altering prion protein misfolding for therapy and diagnosis of transmissible spongiform encephalopathies

C. Soto

Biochem Soc Trans (2002) 30 (3): A57.

View Articletitled, Altering prion protein misfolding for therapy and diagnosis of transmissible spongiform encephalopathies

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The role of poly-glutamine sequences in Huntington's disease

Stephen Davies

Biochem Soc Trans (2002) 30 (3): A57.

View Articletitled, The role of poly-glutamine sequences in Huntington's disease

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Quantitative detection and identification of amyloid beta peptides directly from crude biological samples using the ProteinChip® Biology System

S. C. Cleverley

Biochem Soc Trans (2002) 30 (3): A57.

View Articletitled, Quantitative detection and identification of amyloid beta peptides directly from crude biological samples using the ProteinChip® Biology System

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Lessons from the Type II Family of G-protein-Coupled Receptors; Ligands, Receptor Structure and Function

Transcriptional regulation of the human calcitonin receptor gene

M. Pondel; C. Jagger; G. Partington

Biochem Soc Trans (2002) 30 (3): A57.

View Articletitled, Transcriptional regulation of the human calcitonin receptor gene

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Corticotropin releasing hormone receptors: regulation of expression and signaling properties

Edward W. Hillhouse

Biochem Soc Trans (2002) 30 (3): A58.

View Articletitled, Corticotropin releasing hormone receptors: regulation of expression and signaling properties

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Adrenomedullin: receptor and signal transduction

D. M. Smith

Biochem Soc Trans (2002) 30 (3): A58.

View Articletitled, Adrenomedullin: receptor and signal transduction

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Identification of the Secretin, VIP and glucagon binding sites: from chimeric receptors to point mutations

M. Waelbroeck; J. Perret; P. Vertongen; M. Van Craenenbroeck; P. Robberecht

Biochem Soc Trans (2002) 30 (3): A58.

View Articletitled, Identification of the Secretin, VIP and glucagon binding sites: from chimeric receptors to point mutations

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Additional Signals from PAC/VPAC family receptors

R. Mitchell

Biochem Soc Trans (2002) 30 (3): A58.

View Articletitled, Additional Signals from PAC/VPAC family receptors

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The structure & function of the GLP-1 receptor

Dan Donnelly

Biochem Soc Trans (2002) 30 (3): A59.

View Articletitled, The structure & function of the GLP-1 receptor

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A small sequence in the third intracellular loop of the VPAC₁ receptor is responsible for its efficient coupling to the calcium effector

I. Langer; P. Vertongen; J. Perret; M. Waelbroeck; P. Robberecht

Biochem Soc Trans (2002) 30 (3): A59.

View Articletitled, A small sequence in the third intracellular loop of the VPAC1 receptor is responsible for its efficient coupling to the calcium effector

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Transcriptional regulation of the human CRLR in microvascular endothelial cells

L. L. Nikitenko; C. M. P. Rees; R. Bicknell

Biochem Soc Trans (2002) 30 (3): A59.

View Articletitled, Transcriptional regulation of the human CRLR in microvascular endothelial cells

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The interaction of CGRP with its receptors

D. R. Poyner; A. C. Conner; S. G. Howitt; D. L. Hay; U. Langel; K. Kilk; D. M. Smith; M. Wheatley

Biochem Soc Trans (2002) 30 (3): A59.

View Articletitled, The interaction of CGRP with its receptors

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The functional relevance of G protein receptor associated proteins exemplified by the receptor-activity-modifying proteins (RAMP)

J. A. Fischer

Biochem Soc Trans (2002) 30 (3): A60.

View Articletitled, The functional relevance of G protein receptor associated proteins exemplified by the receptor-activity-modifying proteins (RAMP)

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Receptor component protein (rep): a member of a multi-protein complex required for G protein-coupled signal transduction

M. A. Prado; B. Evans-Bains; I. M. Dickerson

Biochem Soc Trans (2002) 30 (3): A60.

View Articletitled, Receptor component protein (rep): a member of a multi-protein complex required for G protein-coupled signal transduction

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Interactions of G-protein coupled receptors with synaptic scaffolding proteins

H.-J. Kreienkamp; M. Soltau; D. Richter; T. Boeckers

Biochem Soc Trans (2002) 30 (3): A60.

View Articletitled, Interactions of G-protein coupled receptors with synaptic scaffolding proteins

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In-vitro folding and functional characterization of the extracellular domain of G protein-coupled receptors

A. Kuntzsch; U. Grauschopf; A. Bazarsuren; K. Wenig; H. Lilie; R. Rudolph

Biochem Soc Trans (2002) 30 (3): A60.

View Articletitled, In-vitro folding and functional characterization of the extracellular domain of G protein-coupled receptors

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The development and potential of non-peptide antagonists for calcitonin-gene related peptide receptors

M. Schindler; K. Arndt; D. Wu; H. Doods

Biochem Soc Trans (2002) 30 (3): A61.

View Articletitled, The development and potential of non-peptide antagonists for calcitonin-gene related peptide receptors

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RAMPs interact with and modulate the signalling of VPAC1 receptors

P. M. Sexton; M. Morfis; G. Christopoulos; M. Laburthe; A. Couvineau; A. Christopoulos

Biochem Soc Trans (2002) 30 (3): A61.

View Articletitled, RAMPs interact with and modulate the signalling of VPAC1 receptors

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Bioinformatics and type II GPCRs

S. M. Foord

Biochem Soc Trans (2002) 30 (3): A61.

View Articletitled, Bioinformatics and type II GPCRs

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14-3-3 Proteins in Cell Regulation

14-3-3 structure, function and role in neurodegenerative diseases, trafficking and nuclear signalling

A. Aitken; H. C. Baxter; T. Dubois; S. Mackie; A. Peden; E. Zemlickova

Biochem Soc Trans (2002) 30 (3): A61.

View Articletitled, 14-3-3 structure, function and role in neurodegenerative diseases, trafficking and nuclear signalling

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The molecular architecture of kinase/phosphatase signalling complexes

John Scott

Biochem Soc Trans (2002) 30 (3): A62.

View Articletitled, The molecular architecture of kinase/phosphatase signalling complexes

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Prosurvival Function of 14-3-3 Proteins

S. C. Masters; R. R. Subramanian; A. Truong; H. Yang; K. Fujii; H. Zhang; H. Fu

Biochem Soc Trans (2002) 30 (3): A62.

View Articletitled, Prosurvival Function of 14-3-3 Proteins

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Structure and function of a cAMP operated 14-3-3 binding switch: essential role in biological timing

D. C. Klein

Biochem Soc Trans (2002) 30 (3): A62.

View Articletitled, Structure and function of a cAMP operated 14-3-3 binding switch: essential role in biological timing

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Structure and function of tomato 14-3-3 protein isoforms

M. R. Roberts; G. L. de Bruxelles; A. P. Brown; T. C. McCabe

Biochem Soc Trans (2002) 30 (3): A62.

View Articletitled, Structure and function of tomato 14-3-3 protein isoforms

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Signalling pathways that target diverse plant and human 14-3-3-binding partners

C. MacKintosh; M. Pozuelo Rubio; J. Harthill; A. Kulma; B. Wong; J. Diplexcito

Biochem Soc Trans (2002) 30 (3): A63.

View Articletitled, Signalling pathways that target diverse plant and human 14-3-3-binding partners

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Use of cerebrospinal fluid 14-3-3 analysis in the diagnosis of sporadic and variant Creutzfeldt-Jakob disease

A. J. E. Green; R. S. G. Knight; R. G. Will

Biochem Soc Trans (2002) 30 (3): A63.

View Articletitled, Use of cerebrospinal fluid 14-3-3 analysis in the diagnosis of sporadic and variant Creutzfeldt-Jakob disease

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Analysis of 14-3-3 isoforms in the lateral geniculate nucleus in murine brain

H. C. Baxter; W-G. Liu; S. J. H. Clokie; A. Aitken; J. R. Fraser

Biochem Soc Trans (2002) 30 (3): A63.

View Articletitled, Analysis of 14-3-3 isoforms in the lateral geniculate nucleus in murine brain

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In vivo association of 14-3-3 isoforms with mammalian origins of DNA replication

O. Novac; D. Alvarez; G. B. Price; M. Zannis-Hadjopoulos

Biochem Soc Trans (2002) 30 (3): A63.

View Articletitled, In vivo association of 14-3-3 isoforms with mammalian origins of DNA replication

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IGF-1 induces phosphorylation of two novel residues of FKHR

Graham Rena; Yvonne L. Woods; Alan R. Prescott; Mark Peggie; Terry G. Unterman; Michayla R. Williams; Philip Cohen

Biochem Soc Trans (2002) 30 (3): A64.

View Articletitled, IGF-1 induces phosphorylation of two novel residues of FKHR

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Multiple roles for 14-3-3 proteins in nucleo-cytoplasmic transport

A. Brunet; F. Kanai; J. Stehn; M. E. Greenberg; M. B. Yaffe

Biochem Soc Trans (2002) 30 (3): A64.

View Articletitled, Multiple roles for 14-3-3 proteins in nucleo-cytoplasmic transport

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14-3-3 as cruciform-binding DNA replication protein

M. ZannisHadjopoulos; O. Novac; D. Alvarez; G. B. Price

Biochem Soc Trans (2002) 30 (3): A64.

View Articletitled, 14-3-3 as cruciform-binding DNA replication protein

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ExoS binds its co-factor 14-3-3 through a non-phosphorylated motif

B. Hallberg

Biochem Soc Trans (2002) 30 (3): A64.

View Articletitled, ExoS binds its co-factor 14-3-3 through a non-phosphorylated motif

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Transgenic 14-3-3 isoforms in plants

Jan Szopa

Biochem Soc Trans (2002) 30 (3): A65.

View Articletitled, Transgenic 14-3-3 isoforms in plants

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Phosphorylation-independent interaction between 14-3-3 protein and the plant plasma membrane H⁺-ATPase

A. T. Fuglsang; K. Bych; T. P. Jahn; M. G. Palmgren

Biochem Soc Trans (2002) 30 (3): A65.

View Articletitled, Phosphorylation-independent interaction between 14-3-3 protein and the plant plasma membrane H+-ATPase

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Plants call 14-3-3 for transport assistance

A. H. de Boer; I. Roobeek; M. P. Sinnige; P. W. J. van den Wijngaard

Biochem Soc Trans (2002) 30 (3): A65.

View Articletitled, Plants call 14-3-3 for transport assistance

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Mediation and Modulation of Antibody Function

X-ray crystallographic studies of IgG-FcγR interactions

P. Sondermann; V. Oosthuizen

Biochem Soc Trans (2002) 30 (3): A65.

View Articletitled, X-ray crystallographic studies of IgG-FcγR interactions

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Engineering therapeutic antibodies for improved function

L. G. Presta; R. L. Shields; A. K. Namenuk; K. Hong; Y. G. Meng

Biochem Soc Trans (2002) 30 (3): A66.

View Articletitled, Engineering therapeutic antibodies for improved function

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IgE Fc structure and receptor interactions

A. J. Beavil; R. L. Beavil; T. Wan; S. M. Fabiane; J. M. McDonnell; H. J. Gould; B. J. Sutton

Biochem Soc Trans (2002) 30 (3): A66.

View Articletitled, IgE Fc structure and receptor interactions

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The human IgA-FcαR interaction and its blockade by streptococcal IgA binding proteins

Jenny M. Woof

Biochem Soc Trans (2002) 30 (3): A66.

View Articletitled, The human IgA-FcαR interaction and its blockade by streptococcal IgA binding proteins

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The contrasting IgG-binding interactions of human and herpes simplex virus Fc receptors

K. L. Armour; A. Atherton; L. M. Williamson; M. R. Clark

Biochem Soc Trans (2002) 30 (3): A66.

View Articletitled, The contrasting IgG-binding interactions of human and herpes simplex virus Fc receptors

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Novel antibody therapeutics for treatment of cancer and inflammation

Jan van de Winkel

Biochem Soc Trans (2002) 30 (3): A67.

View Articletitled, Novel antibody therapeutics for treatment of cancer and inflammation

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Pepbodies and Troybodies

I. Sandlie

Biochem Soc Trans (2002) 30 (3): A67.

View Articletitled, Pepbodies and Troybodies

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Bispecific antibodies targeting cancer cells

Matthias Peipp; Thomas Valerius

Biochem Soc Trans (2002) 30 (3): A67.

View Articletitled, Bispecific antibodies targeting cancer cells

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Prions: conformations, diagnosis, therapy

R. Anthony Williamson

Biochem Soc Trans (2002) 30 (3): A67.

View Articletitled, Prions: conformations, diagnosis, therapy

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Formatting antibody fragments to mediate specific therapeutic functions

A. N. C. Weir; A. Nesbitt; A. Chapman; A. Popplewell; P. Antoniw; A. D. G. Lawson

Biochem Soc Trans (2002) 30 (3): A68.

View Articletitled, Formatting antibody fragments to mediate specific therapeutic functions

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Amino acid sequence requirements in the human IgAl hinge for cleavage by streptococcal IgAl proteases

B. W. Senior; M. R. Batten; M. Kilian; J. M. Woof

Biochem Soc Trans (2002) 30 (3): A68.

View Articletitled, Amino acid sequence requirements in the human IgAl hinge for cleavage by streptococcal IgAl proteases

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A single-domain antibody fragment that stabilises the native state of two amyloidogenic lysozyme variants and hence prevents aggregation

M. Dumoulin; A. Last; D. Canet; L. Wyns; S. Muyldermans; A. Matagne; C. Redfield; C. V. Robinson; C. M. Dobson

Biochem Soc Trans (2002) 30 (3): A68.

View Articletitled, A single-domain antibody fragment that stabilises the native state of two amyloidogenic lysozyme variants and hence prevents aggregation

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Red blood cells (RBC) coated with IgG anti-D bind transforming growth factor-beta (TGF-beta)

B. M. Kumpel

Biochem Soc Trans (2002) 30 (3): A68.

View Articletitled, Red blood cells (RBC) coated with IgG anti-D bind transforming growth factor-beta (TGF-beta)

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Targeted cytokine delivery to neuroblastoma

P. K. Dehal; M. J. Embleton; J. T. Kemshead; R. E. Hawkins

Biochem Soc Trans (2002) 30 (3): A69.

View Articletitled, Targeted cytokine delivery to neuroblastoma

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Neurodegeneration

Characterisation of thermodynamic diversity between TSE agent strains

R. A. Somerville; R. C. Oberthr; U. Havekost; F. MacDonald; A. G. Dickinsonü

Biochem Soc Trans (2002) 30 (3): A69.

View Articletitled, Characterisation of thermodynamic diversity between TSE agent strains

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An investigation into the mechanism of toxicity of amyloid-forming proteins and peptides

I. S. Turnbull; B. J. Tabner; D. Allsop; O. M. A. El-Agnaf; S. Moore; Y. Davies

Biochem Soc Trans (2002) 30 (3): A69.

View Articletitled, An investigation into the mechanism of toxicity of amyloid-forming proteins and peptides

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Heparan sulphate binds the aspartic protease β-Secretase and regulates cleavage of APP

Zoe Scholefield; Gareth Wayne; Augustin Amour; Edwin Yates; Bill McDowell; Jeremy Turnbull

Biochem Soc Trans (2002) 30 (3): A69.

View Articletitled, Heparan sulphate binds the aspartic protease β-Secretase and regulates cleavage of APP

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Does pentosan polysulphate have prophylactic potential for transmissible spongiform encephalopathies?

C. F. Farquhar; I. McConnell; J. Graham; S. Cumming; G. R. Barclay; A. Boyle; M. L. Turner; M. E. Bruce

Biochem Soc Trans (2002) 30 (3): A70.

View Articletitled, Does pentosan polysulphate have prophylactic potential for transmissible spongiform encephalopathies?

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Controlled release of cytochrome c from functional brain mitochondria; implications for apoptotic mechanisms in neurdegenerative disease

R. A. Clayton; M. A. Sharpe; J. B. Clark; T. E. Bates

Biochem Soc Trans (2002) 30 (3): A70.

View Articletitled, Controlled release of cytochrome c from functional brain mitochondria; implications for apoptotic mechanisms in neurdegenerative disease

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Chronic nicotine treatment reduces beta-amyloidosis

J. Court; E. Hellstrom-Lindhal; M. Lee; M. Johnson; M. Mousavi; R. Hall; E. Perry; I. Bednar; A. Nordberg

Biochem Soc Trans (2002) 30 (3): A70.

View Articletitled, Chronic nicotine treatment reduces beta-amyloidosis

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Changes in Nestin and AMPA receptors are associated with preconditioning of the mouse cortex by repetitive spreading depression

P. L. Chazot; O. V. Godukhin; T. P. Obrenovitch

Biochem Soc Trans (2002) 30 (3): A70.

View Articletitled, Changes in Nestin and AMPA receptors are associated with preconditioning of the mouse cortex by repetitive spreading depression

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An investigation in changes in gene regulation and subsequent signal transduction activation after ischemic stroke

Nicholas Mitsios; John Gaffney; Pat Kumar; Shant Kumar; Mark Slevin

Biochem Soc Trans (2002) 30 (3): A71.

View Articletitled, An investigation in changes in gene regulation and subsequent signal transduction activation after ischemic stroke

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Therapeutics for Alzheimer's disease

T. Wisniewski

Biochem Soc Trans (2002) 30 (3): A71.

View Articletitled, Therapeutics for Alzheimer's disease

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Assembly of haem cofactors into diverse haemoproteins

Q. Cheng; A. Smith

Biochem Soc Trans (2002) 30 (3): A71.

View Articletitled, Assembly of haem cofactors into diverse haemoproteins

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Aminolevulic acid transport in murine mammary adenocarcinoma cells

M. Bermudez Moretti; S. Correa Garcia; C. Perotti; A. Casas; A. Batlle

Biochem Soc Trans (2002) 30 (3): A71.

View Articletitled, Aminolevulic acid transport in murine mammary adenocarcinoma cells

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The effect of NO-donors on sulfur amino acids produced by rat hepatoma cells

M. Abulahbas; K. Naseem; A. Nicolaou

Biochem Soc Trans (2002) 30 (3): A72.

View Articletitled, The effect of NO-donors on sulfur amino acids produced by rat hepatoma cells

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Pharmacokinetics of PPIX synthesis induced by administration of ALA and He-ALA

C. Perotti; A. Casas; H. Fukuda; A. Batlle

Biochem Soc Trans (2002) 30 (3): A72.

View Articletitled, Pharmacokinetics of PPIX synthesis induced by administration of ALA and He-ALA

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Genotype/phenotype correlation in patients with Erythropoietic Protoporphyria

V. Parera; R. Koole; G. Minderman; M. V. Rossetti; A. Batlle; F. W. M. de Rooij

Biochem Soc Trans (2002) 30 (3): A72.

View Articletitled, Genotype/phenotype correlation in patients with Erythropoietic Protoporphyria

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Oxidative stress induced by Griseofulvin in mice liver

S. Afonso; V. Rouvier Garay; M. Martinez; A. Molinari; A. Batlle

Biochem Soc Trans (2002) 30 (3): A72.

View Articletitled, Oxidative stress induced by Griseofulvin in mice liver

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Preliminary studies about the effect of acute and chronic ALA intoxication in brain mice

J. A. Rodriguez; A. M. Buzaleh; A. Batlle

Biochem Soc Trans (2002) 30 (3): A73.

View Articletitled, Preliminary studies about the effect of acute and chronic ALA intoxication in brain mice

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Spectroscopic characterisation of Cytochrome cbb₃ oxidase from Pseudomonas stutzeri

R. S. Pitcher; M. R. Cheesman; T. Brittain; N. J. Watmough

Biochem Soc Trans (2002) 30 (3): A73.

View Articletitled, Spectroscopic characterisation of Cytochrome cbb3 oxidase from Pseudomonas stutzeri

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An investigation into the mechanism of SirB from Bacillus megaterium - a sirohydrochlorin ferrochelatase

H. K. Leech; E. Raux-Deery; M. J. Warren

Biochem Soc Trans (2002) 30 (3): A73.

View Articletitled, An investigation into the mechanism of SirB from Bacillus megaterium - a sirohydrochlorin ferrochelatase

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Cloning, expression and characterisation of ALAD from the deep-sea fish Coryphaenoides armatus

A. A. Brindley; D. M. Hunt; J. C. Partridge; M. J. Warren

Biochem Soc Trans (2002) 30 (3): A73.

View Articletitled, Cloning, expression and characterisation of ALAD from the deep-sea fish Coryphaenoides armatus

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Haem A synthesis in Bacillus subtilis: stucture and function of CtaA

M. Throne-Holst; L. Hederstedt

Biochem Soc Trans (2002) 30 (3): A74.

View Articletitled, Haem A synthesis in Bacillus subtilis: stucture and function of CtaA

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Cobalamin (Vitamin B₁₂) biosynthesis in Rhodobacter capsulatus.

H. M. McGoldrick; E. Deery; M. Warren

Biochem Soc Trans (2002) 30 (3): A74.

View Articletitled, Cobalamin (Vitamin B12) biosynthesis in Rhodobacter capsulatus.

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Inhibition of cytochrome c oxidase by nitrite and nitric oxide:reversible and irreversible

A. Mann; P. Nicholls; M. Sharpe; C. E. Cooper

Biochem Soc Trans (2002) 30 (3): A74.

View Articletitled, Inhibition of cytochrome c oxidase by nitrite and nitric oxide:reversible and irreversible

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Spectroscopic characterisation of the substrate binding properties of NADPH:protochlorophyllide oxidoreductase (POR)

Derren J. Heyes; C. Neil Hunter

Biochem Soc Trans (2002) 30 (3): A74.

View Articletitled, Spectroscopic characterisation of the substrate binding properties of NADPH:protochlorophyllide oxidoreductase (POR)

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Two enzymes for oxygen-dependent and independent decarboxylation of coproporphyrinogen III during bacterial tetrapyrrole biosynthesis

G. Layer; E. Mahlitz; D. Breckau; D. Jahn

Biochem Soc Trans (2002) 30 (3): A75.

View Articletitled, Two enzymes for oxygen-dependent and independent decarboxylation of coproporphyrinogen III during bacterial tetrapyrrole biosynthesis

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Mechanistic insights into flavocytochrome c₃, the soluble fumarate reductase from Shewanella frigidimarina

E. L. Rothery; K. L. Pankhurst; C. S. Miles; C. G. Mowat; G. A. Reid; S. K. Chapman

Biochem Soc Trans (2002) 30 (3): A75.

View Articletitled, Mechanistic insights into flavocytochrome c3, the soluble fumarate reductase from Shewanella frigidimarina

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The coupling of ATP hydrolysis to metal ion insertion into porphyrins by magnesium chelatase

J. D. Reid; C. N. Hunter

Biochem Soc Trans (2002) 30 (3): A75.

View Articletitled, The coupling of ATP hydrolysis to metal ion insertion into porphyrins by magnesium chelatase

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The role of membrane bound tetraheme CymA in the anaerobic respiration of Shewanella oneidensis MR-1

C. Schwalb; S. K. Chapman; G. A. Reid

Biochem Soc Trans (2002) 30 (3): A75.

View Articletitled, The role of membrane bound tetraheme CymA in the anaerobic respiration of Shewanella oneidensis MR-1

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Novel respiratory flavocytochromes of Shewanella oneidensis MR-1

M. Bilsland; M. D. Walkinshaw; G. A. Reid

Biochem Soc Trans (2002) 30 (3): A76.

View Articletitled, Novel respiratory flavocytochromes of Shewanella oneidensis MR-1

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Cobalamin Synthesis in Pseudomonas aeruginosa

Ross Graham; Anastasia Papakonstantinopoulou; Carly Crampton; Michael Curtis; Martin Warren

Biochem Soc Trans (2002) 30 (3): A76.

View Articletitled, Cobalamin Synthesis in Pseudomonas aeruginosa

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Spectral properties of bacterial nitric oxide reductase

Sarah J. Field; Louise Prior; M. Dolores Roldán; Myles R. Cheesman; Andrew J. Thomson; Stephen Spiro; Julea Butt; Nicholas J. Watmough; David J. Richardson

Biochem Soc Trans (2002) 30 (3): A76.

View Articletitled, Spectral properties of bacterial nitric oxide reductase

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Studies on 5-aminolaevulinic acid dehydratase from Pisum sativum

J. H. Youell; M. Sarwar; K-M. Cheung; P. M. Shoolingin-Jordan

Biochem Soc Trans (2002) 30 (3): A76.

View Articletitled, Studies on 5-aminolaevulinic acid dehydratase from Pisum sativum

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Studies on human recombinant 5-aminolaevulinic acid dehydratase and human recombinant porphobilinogen deaminase

D. Butler; M. Sarwar; P. M. Shoolingin-Jordan

Biochem Soc Trans (2002) 30 (3): A77.

View Articletitled, Studies on human recombinant 5-aminolaevulinic acid dehydratase and human recombinant porphobilinogen deaminase

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Preliminary NMR analysis of uroporphyrinogen synthase

D. I. Kahari; M. P. Crump; P. M. Shoolingin-Jordan

Biochem Soc Trans (2002) 30 (3): A77.

View Articletitled, Preliminary NMR analysis of uroporphyrinogen synthase

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The expression, purification and steady state analysis of magnesium protoporphyrin IX methyltransferase from Synechocystis PCC6803

M. Shepherd; C. N. Hunter

Biochem Soc Trans (2002) 30 (3): A77.

View Articletitled, The expression, purification and steady state analysis of magnesium protoporphyrin IX methyltransferase from Synechocystis PCC6803

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20S Proteasomal degradation of α-synuclein does not generate the non-β-amyloid plaque component (NAC)

R. Layfield; G. K. Tofaris; M. P. Mee; K. Bailey; M. G. Spillantini

Biochem Soc Trans (2002) 30 (3): A77.

View Articletitled, 20S Proteasomal degradation of α-synuclein does not generate the non-β-amyloid plaque component (NAC)

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Inhibition of Toxicity and protofibril formation in the β-amyloid peptide β(25–35) using N-Methylated derivatives

A. J. Doig; E. Hughes; R. M. Burke; T. J. Su; R. K. Heenan; J. Lu

Biochem Soc Trans (2002) 30 (3): A78.

View Articletitled, Inhibition of Toxicity and protofibril formation in the β-amyloid peptide β(25–35) using N-Methylated derivatives

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Chronic nicotine treatment reduces beta-amyloidosis

J. Court; E. Hellstrom-Lindhal; M. Lee; M. Johnson; M. Mousavi; R. Hall; E. Perry; I. Bednar; A. Nordberg

Biochem Soc Trans (2002) 30 (3): A78.

View Articletitled, Chronic nicotine treatment reduces beta-amyloidosis

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Proteolytic processing of the amyloid precursor protein by α-secretase

T. M. J. Allinson; A. J. Turner; N. M. Hooper

Biochem Soc Trans (2002) 30 (3): A78.

View Articletitled, Proteolytic processing of the amyloid precursor protein by α-secretase

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Heparan sulphate binds the aspartic protease β-secretase and regulates cleavage of APP

Zoe Scholefield; Gareth Wayne; Augustin Amour; Edwin Yates; Bill McDowell; Jeremy Turnbull

Biochem Soc Trans (2002) 30 (3): A78.

View Articletitled, Heparan sulphate binds the aspartic protease β-secretase and regulates cleavage of APP

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Altered processing of the Alzheimer's amyloid precursor protein in human neuroblastoma cells expressing the prion protein

E. T. Parkin; A. J. Turner; N. M. Hooper

Biochem Soc Trans (2002) 30 (3): A79.

View Articletitled, Altered processing of the Alzheimer's amyloid precursor protein in human neuroblastoma cells expressing the prion protein

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An N-methylated analogue inhibits α-synuclein(68–78) aggregation

G. B. Irvine; A. M. Bodles; O. M. A. El-Agnaf; D. J. S. Guthrie; B. Greer

Biochem Soc Trans (2002) 30 (3): A79.

View Articletitled, An N-methylated analogue inhibits α-synuclein(68–78) aggregation

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Role of the transmembrane form of the prion protein in neurodegeneration

Andrew Gillott; Nigel M. Hooper

Biochem Soc Trans (2002) 30 (3): A79.

View Articletitled, Role of the transmembrane form of the prion protein in neurodegeneration

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Characterisation of thermodynamic diversity between TSE agent strains

R. A. Somerville; R. C. Oberthür; F. MacDonald; U. Havekost; A. G. Dickinson

Biochem Soc Trans (2002) 30 (3): A79.

View Articletitled, Characterisation of thermodynamic diversity between TSE agent strains

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Polyglutamine conformation in GST-polyglutamine fusion proteins

L. Masino; G. Kelly; K. Leonard; Y. Trottier; A. Pastore

Biochem Soc Trans (2002) 30 (3): A80.

View Articletitled, Polyglutamine conformation in GST-polyglutamine fusion proteins

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Amyloid sequences and human prion sequences are able to functionally replace repeat regions of the prion-forming domain of yeast Sup35p

A. D. Dunn; S. N. Parham; C. G. Resende; M. F. Tuite

Biochem Soc Trans (2002) 30 (3): A80.

View Articletitled, Amyloid sequences and human prion sequences are able to functionally replace repeat regions of the prion-forming domain of yeast Sup35p

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PrP gene expression regulation in scrapie

S. T. G. Burgess; W. Goldmann; G. O'Neill; N. Hunter

Biochem Soc Trans (2002) 30 (3): A80.

View Articletitled, PrP gene expression regulation in scrapie

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Amyloid fibril formation by human stefin B; influence of solvent composition, trifluoroethanol and temperature

E. Zerovnik

Biochem Soc Trans (2002) 30 (3): A80.

View Articletitled, Amyloid fibril formation by human stefin B; influence of solvent composition, trifluoroethanol and temperature

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A correlation study of human serum Aβ1–42 and serum cholesterol measurements

G. L. Gibson; E. B. Renvoize; M. C. Dale; P. Bladon; D. Allsop

Biochem Soc Trans (2002) 30 (3): A81.

View Articletitled, A correlation study of human serum Aβ1–42 and serum cholesterol measurements

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Cyclodextrin dimers and trimers inhibit the aggregation of β-amyloid

S. Moore; J. Askew; G. L. Gibson; D. K. Lueng; R. Breslow; O. M. A. El-Agnaf; D. Allsop

Biochem Soc Trans (2002) 30 (3): A81.

View Articletitled, Cyclodextrin dimers and trimers inhibit the aggregation of β-amyloid

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A beta-site amyloid precursor protein cleaving enzyme (BACE) assay

S. McMeekin; C. H. Williams; J. Cummings; J. Law; B. Greer; J. A. Johnston

Biochem Soc Trans (2002) 30 (3): A81.

View Articletitled, A beta-site amyloid precursor protein cleaving enzyme (BACE) assay

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Does pentosan polysulphate have prophylactic potential for transmissible spongiform encephalopathies?

C. F. Farquhar; I. McConnell; J. Graham; S. Cumming; R. Prescott; G. R. Barclay; A. Boyle; M. L. Turner; M. E. Bruce

Biochem Soc Trans (2002) 30 (3): A81.

View Articletitled, Does pentosan polysulphate have prophylactic potential for transmissible spongiform encephalopathies?

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New analytical methods for the study of protein aggregation in real time

Susan Moore; Omar El Agnaf; Yvonne Davies; David Allsop; Marcus Swann

Biochem Soc Trans (2002) 30 (3): A82.

View Articletitled, New analytical methods for the study of protein aggregation in real time

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Expression of cellular prion protein in Xenopus oocytes

John G. Connolly; Roth J. Tate; Glenn C. Telling; Jan Fraser; Debbie Brown; Mark W. Head

Biochem Soc Trans (2002) 30 (3): A82.

View Articletitled, Expression of cellular prion protein in Xenopus oocytes

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Neurotoxicity of Abri and Adan

Nicola Gunasekera; Maria Lee; Sudhara Nagala; Omar El-Agnaf; Victor Lelyveld; Brian Austen

Biochem Soc Trans (2002) 30 (3): A82.

View Articletitled, Neurotoxicity of Abri and Adan

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What constitutes infectivity in Transmissible Spongiform Encephalopathy disease?

SL Campbell; R. Barron; J. Shaw; J. Manson

Biochem Soc Trans (2002) 30 (3): A82.

View Articletitled, What constitutes infectivity in Transmissible Spongiform Encephalopathy disease?

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Characterisation of amyloid fibrils formed from β-lactoglobulin

Walraj S. Gosal; Simon B. Ross-Murphy; Paul D. A. Pudney; Allan H. Clark

Biochem Soc Trans (2002) 30 (3): A83.

View Articletitled, Characterisation of amyloid fibrils formed from β-lactoglobulin

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The role of cholesterol in the processing β-secretase ASP-2

Christina Sidera; Jocelyn Frampong-Manso; Chibuu Liu; Brian Austen

Biochem Soc Trans (2002) 30 (3): A83.

View Articletitled, The role of cholesterol in the processing β-secretase ASP-2

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Changes in Nestin and AMPA receptors are associated with preconditioning of the mouse cortex by repetitive spreading depression

P. L. Chazot; O. V. Godukhin; T. P. Obrenovitch

Biochem Soc Trans (2002) 30 (3): A83.

View Articletitled, Changes in Nestin and AMPA receptors are associated with preconditioning of the mouse cortex by repetitive spreading depression

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Molecular characterization of protein interactions essential for neurotransmitter exocytosis: munc18 and mint

M. Okamoto; M. Sakanaka

Biochem Soc Trans (2002) 30 (3): A83.

View Articletitled, Molecular characterization of protein interactions essential for neurotransmitter exocytosis: munc18 and mint

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Haem oxygenase/nitric oxide synthase interaction: a role in neurodegeneration?

A. J. Heslegrave; V. C. Stewart; M. Sharpe; V. Calabrese; J. B. Clark

Biochem Soc Trans (2002) 30 (3): A84.

View Articletitled, Haem oxygenase/nitric oxide synthase interaction: a role in neurodegeneration?

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An investigation in changes in gene regulation and subsequent signal transduction activation after ischemic stroke

Nicholas Mitsios; John Gaffney; Pat Kumar; Shant Kumar; Mark Slevin

Biochem Soc Trans (2002) 30 (3): A84.

View Articletitled, An investigation in changes in gene regulation and subsequent signal transduction activation after ischemic stroke

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Controlled release of cytochrome c from functional brain mitochondria; implications for apoptotic mechanisms in neur-degenerative disease

R. A. Clayton; M. A. Sharpe; J. B. Clark; T. E. Bates

Biochem Soc Trans (2002) 30 (3): A84.

View Articletitled, Controlled release of cytochrome c from functional brain mitochondria; implications for apoptotic mechanisms in neur-degenerative disease

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Molecular and cellular characterisation of the Prion-like protein Doppel

A. P. Ison; N. M. Hooper

Biochem Soc Trans (2002) 30 (3): A84.

View Articletitled, Molecular and cellular characterisation of the Prion-like protein Doppel

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An investigation into the mechanism of toxicity of amyloid-forming proteins and peptides

I. S. Turnbull; B. J. Tabner; O. M. A. El-Agnaf; S. Moore; Y. Davies; D. Allsop

Biochem Soc Trans (2002) 30 (3): A85.

View Articletitled, An investigation into the mechanism of toxicity of amyloid-forming proteins and peptides

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Calcium-dependent proteolysis of adenylyl cyclase IX (ACIX)

F. A. Antoni; J. Simpson

Biochem Soc Trans (2002) 30 (3): A85.

View Articletitled, Calcium-dependent proteolysis of adenylyl cyclase IX (ACIX)

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SOD1 aggregation in familial amyotrophic lateral sclerosis (FALS)

T. P. Beaujeux; E. L. Schofield; P. J. Shaw; J. D. Wood

Biochem Soc Trans (2002) 30 (3): A85.

View Articletitled, SOD1 aggregation in familial amyotrophic lateral sclerosis (FALS)

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Poster withdrawn

Biochem Soc Trans (2002) 30 (3): A85.

View Articletitled, Poster withdrawn

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Heat shock proteins protect PC12 cells from MPP⁺ toxicity

D. J. Quigney; A. Samali; A. M. Gorman

Biochem Soc Trans (2002) 30 (3): A86.

View Articletitled, Heat shock proteins protect PC12 cells from MPP+ toxicity

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Lessons from the Type II Family of G-Protein-Coupled Receptors: Ligands, Receptor Structure and Function

EMR4, a novel EGF-TM7 molecule up-regulated in activated mouse macrophages, is involved in the adhesion to a B lymphoma cell line, A20

Martin Stacey; Gin-Wen Chang; Stephanie Sanos; Laura Chittenden; Lisa Stubbs; Siamon Gordon; Hsi-Hsien Lin

Biochem Soc Trans (2002) 30 (3): A86.

View Articletitled, EMR4, a novel EGF-TM7 molecule up-regulated in activated mouse macrophages, is involved in the adhesion to a B lymphoma cell line, A20

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Adenylyl cyclase 9: biochemical and pharmacological characterisation of recombinantly expressed ‘active core’

A. Haunsø; F. Antoni

Biochem Soc Trans (2002) 30 (3): A86.

View Articletitled, Adenylyl cyclase 9: biochemical and pharmacological characterisation of recombinantly expressed ‘active core’

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The effect on CGRP-binding of mutations to hydrophilic residues within the second transmembrane region of human calcitonin receptor-like receptor (CRLR)

A. C. Conner; S. G. Howitt; M. Wheatley; D. M. Smith; D. R. Poyner

Biochem Soc Trans (2002) 30 (3): A86.

View Articletitled, The effect on CGRP-binding of mutations to hydrophilic residues within the second transmembrane region of human calcitonin receptor-like receptor (CRLR)

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Pharmacology and desensitisation of the human ramp3 and rat crlr combination

D. L. Hay; T. Choksi; D. M. Smith

Biochem Soc Trans (2002) 30 (3): A87.

View Articletitled, Pharmacology and desensitisation of the human ramp3 and rat crlr combination

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Specific interaction between ARF6 and the Hop-1 intracellular loop 3 domain of the human PAC 1 receptor

E. Ronaldson; D. N. Robertson; M. S. Johnson; P. J. Holland; R. Mitchell; E. M. Lutz

Biochem Soc Trans (2002) 30 (3): A87.

View Articletitled, Specific interaction between ARF6 and the Hop-1 intracellular loop 3 domain of the human PAC 1 receptor

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Mitogenic signalling via the parathyroid hormone-related protein receptor

N. G. Anderson; C. Sanderson; N. J. Bundred

Biochem Soc Trans (2002) 30 (3): A87.

View Articletitled, Mitogenic signalling via the parathyroid hormone-related protein receptor

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Selective regulation of secretin receptor responsiveness by PKA and GRK6

R. Ghadessy; E. Kelly

Biochem Soc Trans (2002) 30 (3): A87.

View Articletitled, Selective regulation of secretin receptor responsiveness by PKA and GRK6

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Direct interaction between the threonine 11 of Vasoactive Intestinal Polypeptide (VIP) and tyrosine 184 of the VPAC₂ receptor

I. Nachtergael; P. Vertongen; J. Perret; I. Langer; P. Robberecht; M. Waelbroeck

Biochem Soc Trans (2002) 30 (3): A88.

View Articletitled, Direct interaction between the threonine 11 of Vasoactive Intestinal Polypeptide (VIP) and tyrosine 184 of the VPAC2 receptor

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A small sequence in the third intracellular loop of the VPAC₁ receptor is responsible for its efficient coupling to the calcium effector

I. Langer; P. Vertongen; J. Perret; M. Waelbroeck; P. Robberecht

Biochem Soc Trans (2002) 30 (3): A88.

View Articletitled, A small sequence in the third intracellular loop of the VPAC1 receptor is responsible for its efficient coupling to the calcium effector

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Study of agonist-dependent VPAC₁ receptor phosphorylation

C. Langlet; P. Vertongen; M. Waelbroeck; P. Robberecht

Biochem Soc Trans (2002) 30 (3): A88.

View Articletitled, Study of agonist-dependent VPAC1 receptor phosphorylation

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Interaction of calmodulin with the intracellular C-tails of metabotropic glutamate receptors assayed with the yeast two-hybrid system

B. Pilkington; O. El Far; H. Betz; V. O'Connor

Biochem Soc Trans (2002) 30 (3): A88.

View Articletitled, Interaction of calmodulin with the intracellular C-tails of metabotropic glutamate receptors assayed with the yeast two-hybrid system

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Transcriptional regulation of the human CRLR in microvascular endothelial cells

L. L. Nikitenko; C. M. P. Rees; R. Bicknell

Biochem Soc Trans (2002) 30 (3): A89.

View Articletitled, Transcriptional regulation of the human CRLR in microvascular endothelial cells

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The role of CBP/14-3-3 in DNA replication

D. Alvarez; M. Callejo; O. Novac; G. B. Price; M. Zannis-Hadjopoulos

Biochem Soc Trans (2002) 30 (3): A89.

View Articletitled, The role of CBP/14-3-3 in DNA replication

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In vivo association of 14-3-3 isoforms with mammalian origins of DNA replication

O. Novac; D. Alvarez; G. B. Price; M. Zannis-Hadjopoulos

Biochem Soc Trans (2002) 30 (3): A89.

View Articletitled, In vivo association of 14-3-3 isoforms with mammalian origins of DNA replication

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A docking site on the carboxy-terminus of ERK-2 is essential for different functionality between ERK-1 and ERK-2

N. A. Hernadez-Rodriguez; M. J. Kortenjann; S. W. Doughty; P. E. Shaw

Biochem Soc Trans (2002) 30 (3): A89.

View Articletitled, A docking site on the carboxy-terminus of ERK-2 is essential for different functionality between ERK-1 and ERK-2

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Use of cerebrospinal fluid 14-3-3 analysis in the diagnosis of sporadic and variant Creutzfeldt-Jakob disease

A. J. E. Green; R. S. G. Knight; R. G. Will

Biochem Soc Trans (2002) 30 (3): A90.

View Articletitled, Use of cerebrospinal fluid 14-3-3 analysis in the diagnosis of sporadic and variant Creutzfeldt-Jakob disease

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Approaches to study the structure and function of tomato 14-3-3 protein isoforms

A. P. Brown; T. C. McCabe; M. R. Roberts

Biochem Soc Trans (2002) 30 (3): A90.

View Articletitled, Approaches to study the structure and function of tomato 14-3-3 protein isoforms

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Isolation of a member of the 14-3-3 gene family from a marine alga, Fucus vesiculosus

J. R. Chaseley; C. A. Morris; B. Nicolaus; J. L. Harwood; P. Kille

Biochem Soc Trans (2002) 30 (3): A90.

View Articletitled, Isolation of a member of the 14-3-3 gene family from a marine alga, Fucus vesiculosus

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Temporal nuclear translocation of PKC Isoenzymes during adipocyte differentiation

P. R. Webb; N. G. Anderson

Biochem Soc Trans (2002) 30 (3): A90.

View Articletitled, Temporal nuclear translocation of PKC Isoenzymes during adipocyte differentiation

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Analysis of 14-3-3 isoforms in the lateral geniculate nucleus in murine brain

H. C. Baxter; W-G. Liu; S. J. H. Clokie; A. Aitken; J. R. Fraser

Biochem Soc Trans (2002) 30 (3): A91.

View Articletitled, Analysis of 14-3-3 isoforms in the lateral geniculate nucleus in murine brain

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Early changes in protein kinase c and tubulinα expression in rat liver by phenobarbital

P. Pantasri; K. M. Doyle; R. Rapley; R. Hoffman; J. M. Walker; P. G. Lord; M. J. Skehel; K. Kramer

Biochem Soc Trans (2002) 30 (3): A91.

View Articletitled, Early changes in protein kinase c and tubulinα expression in rat liver by phenobarbital

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Characterisation of the interaction of BCR Kinase with 14-3-3

S. J. H. Clokie; K. Y. Cheng; A. H. Peden; S. Mackie; A. Aitken

Biochem Soc Trans (2002) 30 (3): A91.

View Articletitled, Characterisation of the interaction of BCR Kinase with 14-3-3

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IGF-1 induces phosphorylation of two novel residues of FKHR

Graham Rena; Yvonne L. Woods; Alan R. Prescott; Mark Peggie; Terry G. Unterman; Michayla R. Williams; Philip Cohen

Biochem Soc Trans (2002) 30 (3): A91.

View Articletitled, IGF-1 induces phosphorylation of two novel residues of FKHR

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Anti-malaria immune effector mechanisms recruited by human IgG1 and IgA1 monoclonal antibodies

R. J. Pleass; D. H. McGuinness; A. A. Holder; J. M. Woof

Biochem Soc Trans (2002) 30 (3): A92.

View Articletitled, Anti-malaria immune effector mechanisms recruited by human IgG1 and IgA1 monoclonal antibodies

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Amino acid sequence requirements in the human IgA1 hinge for cleavage by streptococcal IgA1 proteases

B. W. Senior; M. R. Batten; M. Kilian; J. M. Woof

Biochem Soc Trans (2002) 30 (3): A92.

View Articletitled, Amino acid sequence requirements in the human IgA1 hinge for cleavage by streptococcal IgA1 proteases

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Chimeric human antibodies directed against a major surface antigen of Pseudomonas aeruginosa

D. H. McGuinness; R. J. Pleass; B. W. Senior; J. M. Woof

Biochem Soc Trans (2002) 30 (3): A92.

View Articletitled, Chimeric human antibodies directed against a major surface antigen of Pseudomonas aeruginosa

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A solution structural model of human IgA2

P. W. Whitty; A. Robertson; M. A. Kerr; J. M. Woof; S. J. Perkins

Biochem Soc Trans (2002) 30 (3): A92.

View Articletitled, A solution structural model of human IgA2

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A single-domain antibody fragment that stabilises the native state of two amyloidogenic lysozyme variants and hence prevents aggregation

M. Dumoulin; A. Last; D. Canet; L. Wyns; S. Muyldermans; A. Matagne; C. Redfield; C. V. Robinson; C. M. Dobson

Biochem Soc Trans (2002) 30 (3): A93.

View Articletitled, A single-domain antibody fragment that stabilises the native state of two amyloidogenic lysozyme variants and hence prevents aggregation

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Red blood cells (RBC) coated with IgG anti-D bind transforming growth factor-beta (TGF-beta)

B. M. Kumpel

Biochem Soc Trans (2002) 30 (3): A93.

View Articletitled, Red blood cells (RBC) coated with IgG anti-D bind transforming growth factor-beta (TGF-beta)

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Targeted cytokine delivery to neuroblastoma

P. K. Dehal; M. J. Embleton; J. T. Kemshead; R. E. Hawkins

Biochem Soc Trans (2002) 30 (3): A93.

View Articletitled, Targeted cytokine delivery to neuroblastoma

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MISCELLANEOUS

Highly stable single-domain antibody fragments from camelids

M. Dumoulin; K. Conrath; F. Meersman; K. Heremans; S. Muyldermans; L. Wyns; A. Matagne

Biochem Soc Trans (2002) 30 (3): A93.

View Articletitled, Highly stable single-domain antibody fragments from camelids

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Kaempferol metabolism by rat hepatocytes cultured on different collagen substrates

M. Kataropoulou; C. Henderson; M. H. Grant

Biochem Soc Trans (2002) 30 (3): A94.

View Articletitled, Kaempferol metabolism by rat hepatocytes cultured on different collagen substrates

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Cryopreserved rat hepatocyte monolayers

D. Stevenson; C. Morgan; E. Goldie; G. Connel; E. Oliveira; M. H. Grant

Biochem Soc Trans (2002) 30 (3): A94.

View Articletitled, Cryopreserved rat hepatocyte monolayers

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The role of adrenomedullin (AM) and pro-adrenomedullin N-terminal 20 peptide (PAMP) in osteoblast metabolism

S. Papaioannou; S. Kapas; M. C. Meikle; F. McDonald

Biochem Soc Trans (2002) 30 (3): A94.

View Articletitled, The role of adrenomedullin (AM) and pro-adrenomedullin N-terminal 20 peptide (PAMP) in osteoblast metabolism

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Hepatic heme-oxygenase and oxidative stress during short-term treatment with DAB

E. Gerez; F. Caballero; A. Batlle; E. Vazquez

Biochem Soc Trans (2002) 30 (3): A94.

View Articletitled, Hepatic heme-oxygenase and oxidative stress during short-term treatment with DAB

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Scrapie spreads from the gastrointestinal tract to the CNS along autonomic and sensory relays of the peripheral nervous system

P. A. McBride; M. Donaldson; J. Oxley; M. Beekes

Biochem Soc Trans (2002) 30 (3): A95.

View Articletitled, Scrapie spreads from the gastrointestinal tract to the CNS along autonomic and sensory relays of the peripheral nervous system

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Refolding studies of recombinant prp(90–231) in solution

Andy Harvey; Teresa JT Pinheiro

Biochem Soc Trans (2002) 30 (3): A95.

View Articletitled, Refolding studies of recombinant prp(90–231) in solution

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Binding of prion proteins to lipid membranes and implications for prion conversion

Jurate Kazlauskaite; Teresa JT Pinheiro

Biochem Soc Trans (2002) 30 (3): A95.

View Articletitled, Binding of prion proteins to lipid membranes and implications for prion conversion

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γ-secretase enzyme specificity toward cleavage of amyloid precursor protein and Notch

H. D. Lewis; Perez B. I. Revuelta; D. Beher; M. S. Shearman

Biochem Soc Trans (2002) 30 (3): A95.

View Articletitled, γ-secretase enzyme specificity toward cleavage of amyloid precursor protein and Notch

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Investigation into the role of the second and third extracellular loop domains of the glucagon-like peptide-1 receptor in ligand binding and activation

S. Y. Al-Sabah; D. Donnelly

Biochem Soc Trans (2002) 30 (3): A96.

View Articletitled, Investigation into the role of the second and third extracellular loop domains of the glucagon-like peptide-1 receptor in ligand binding and activation

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Overexpression, purification and characterisation of the N-terminal domain of the glucagon-like peptide-1 receptor

R. López de Maturana; D. Donnelly

Biochem Soc Trans (2002) 30 (3): A96.

View Articletitled, Overexpression, purification and characterisation of the N-terminal domain of the glucagon-like peptide-1 receptor

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Alanine scan of the first extracellular loop of the glucagon-like peptide-1 receptor

R. López de Maturana; Janet Treece-Birch; Dan Donnelly

Biochem Soc Trans (2002) 30 (3): A96.

View Articletitled, Alanine scan of the first extracellular loop of the glucagon-like peptide-1 receptor

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Issues

Cover Image

676th Meeting

Tetrapyrroles: their Birth, Life and Death

Amyloidogenic Proteins Involved in Neurodegeneration and Therapeutic Implications

Lessons from the Type II Family of G-protein-Coupled Receptors; Ligands, Receptor Structure and Function

14-3-3 Proteins in Cell Regulation

Mediation and Modulation of Antibody Function

Neurodegeneration