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June 2002
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ISSN 0300-5127
EISSN 1470-8752
In this Issue
676th Meeting
Antibodies: a paradigm for the evolution of molecular recognition
Biochem Soc Trans (2002) 30 (3): A47.
Tetrapyrroles: their Birth, Life and Death
Structure and function of glutamyl-tRNA reductase involved in 5-aminolevulinic acid formation
Biochem Soc Trans (2002) 30 (3): A47.
Mutants, metals and mechanism of 5-aminolaevulinic acid dehydratase
Biochem Soc Trans (2002) 30 (3): A47.
Structural diversity in metal ion chelation, and the structure of uro'gen III synthase
Biochem Soc Trans (2002) 30 (3): A48.
Making light of it: the role of plant heme oxygenases in phytochrome chromophore synthesis
Biochem Soc Trans (2002) 30 (3): A48.
Two enzymes for oxygen-dependent and independent decarboxylation of coproporphyrinogen III during bacterial tetrapyrrole biosynthesis
Biochem Soc Trans (2002) 30 (3): A48.
An investigation into the mechanism of SirB from Bacillus megaterium - a Sirohydrochlorin ferrochelatase
Biochem Soc Trans (2002) 30 (3): A49.
How Nature Sunthesizes Vitamin B12. A Survey of the Last Four Billion Years
Biochem Soc Trans (2002) 30 (3): A49.
Radical journeys catalyzed by B12-dependent methylmalonyl-CoA mutase
Biochem Soc Trans (2002) 30 (3): A49.
Structure of an unusual haemoprotein involved in thiosulfate oxidation
Biochem Soc Trans (2002) 30 (3): A50.
The coupling of ATP hydrolysis to metal ion insertion into porphyrins by magnesium chelatase
Biochem Soc Trans (2002) 30 (3): A50.
Cobalamin (Vitamin B12) Biosynthesis in Rhodobacter capsulatus.
Biochem Soc Trans (2002) 30 (3): A51.
Bacterial cytochrome c nitrite reductase: three-dimensional structure and spectroscopy of the multiheme enzyme
Biochem Soc Trans (2002) 30 (3): A51.
Structure and function of the nickel tetrapyrrole F430 in methanogenic archaea
Biochem Soc Trans (2002) 30 (3): A51.
A universal mechanism for fumarate reduction
Graeme A. Reid; Christopher G. Mowat; Caroline S. Miles; Kate Pankhurst; Malcolm D. Walkinshaw; Stephen K. Chapman
Biochem Soc Trans (2002) 30 (3): A51.
The structure and function of purple bacterial antenna complexes
Biochem Soc Trans (2002) 30 (3): A52.
Spectroscopic characterisation of Cytochrome cbb3 oxidase from Pseudomonas stutzeri
Biochem Soc Trans (2002) 30 (3): A52.
The role of membrane bound tetraheme CymA in the anaerobic respiration of Shewanella oneidensis MR-1
Biochem Soc Trans (2002) 30 (3): A53.
The denitrification pathway of the hyperthermophile Pyrobaculum aerophilum
Biochem Soc Trans (2002) 30 (3): A53.
Amyloidogenic Proteins Involved in Neurodegeneration and Therapeutic Implications
Transgenic models of Alzheimer's disease: behavioural studies and the prospects of therapeutic immunization
Biochem Soc Trans (2002) 30 (3): A55.
Inhibition of toxicity and protofibril formation in the β-amyloid peptide β(25–35) using N-Methylated derivatives
Biochem Soc Trans (2002) 30 (3): A55.
Amyloid fibril formation by human stefin B; influence of solvent composition, trifluoroethanol and temperature
Biochem Soc Trans (2002) 30 (3): A55.
Polyglutamine conformation in GST-polyglutamine fusion proteins
Biochem Soc Trans (2002) 30 (3): A55.
Cell-derived Aβ oligomers: production, activity and inhibition
Biochem Soc Trans (2002) 30 (3): A56.
Altering prion protein misfolding for therapy and diagnosis of transmissible spongiform encephalopathies
Biochem Soc Trans (2002) 30 (3): A57.
Lessons from the Type II Family of G-protein-Coupled Receptors; Ligands, Receptor Structure and Function
Transcriptional regulation of the human calcitonin receptor gene
Biochem Soc Trans (2002) 30 (3): A57.
Corticotropin releasing hormone receptors: regulation of expression and signaling properties
Biochem Soc Trans (2002) 30 (3): A58.
Identification of the Secretin, VIP and glucagon binding sites: from chimeric receptors to point mutations
Biochem Soc Trans (2002) 30 (3): A58.
Transcriptional regulation of the human CRLR in microvascular endothelial cells
Biochem Soc Trans (2002) 30 (3): A59.
The functional relevance of G protein receptor associated proteins exemplified by the receptor-activity-modifying proteins (RAMP)
Biochem Soc Trans (2002) 30 (3): A60.
Receptor component protein (rep): a member of a multi-protein complex required for G protein-coupled signal transduction
Biochem Soc Trans (2002) 30 (3): A60.
Interactions of G-protein coupled receptors with synaptic scaffolding proteins
Biochem Soc Trans (2002) 30 (3): A60.
In-vitro folding and functional characterization of the extracellular domain of G protein-coupled receptors
Biochem Soc Trans (2002) 30 (3): A60.
The development and potential of non-peptide antagonists for calcitonin-gene related peptide receptors
Biochem Soc Trans (2002) 30 (3): A61.
RAMPs interact with and modulate the signalling of VPAC1 receptors
Biochem Soc Trans (2002) 30 (3): A61.
14-3-3 Proteins in Cell Regulation
14-3-3 structure, function and role in neurodegenerative diseases, trafficking and nuclear signalling
Biochem Soc Trans (2002) 30 (3): A61.
The molecular architecture of kinase/phosphatase signalling complexes
Biochem Soc Trans (2002) 30 (3): A62.
Structure and function of a cAMP operated 14-3-3 binding switch: essential role in biological timing
Biochem Soc Trans (2002) 30 (3): A62.
Signalling pathways that target diverse plant and human 14-3-3-binding partners
Biochem Soc Trans (2002) 30 (3): A63.
Use of cerebrospinal fluid 14-3-3 analysis in the diagnosis of sporadic and variant Creutzfeldt-Jakob disease
Biochem Soc Trans (2002) 30 (3): A63.
Analysis of 14-3-3 isoforms in the lateral geniculate nucleus in murine brain
Biochem Soc Trans (2002) 30 (3): A63.
In vivo association of 14-3-3 isoforms with mammalian origins of DNA replication
Biochem Soc Trans (2002) 30 (3): A63.
IGF-1 induces phosphorylation of two novel residues of FKHR
Graham Rena; Yvonne L. Woods; Alan R. Prescott; Mark Peggie; Terry G. Unterman; Michayla R. Williams; Philip Cohen
Biochem Soc Trans (2002) 30 (3): A64.
Multiple roles for 14-3-3 proteins in nucleo-cytoplasmic transport
Biochem Soc Trans (2002) 30 (3): A64.
ExoS binds its co-factor 14-3-3 through a non-phosphorylated motif
Biochem Soc Trans (2002) 30 (3): A64.
Phosphorylation-independent interaction between 14-3-3 protein and the plant plasma membrane H+-ATPase
Biochem Soc Trans (2002) 30 (3): A65.
Mediation and Modulation of Antibody Function
The human IgA-FcαR interaction and its blockade by streptococcal IgA binding proteins
Biochem Soc Trans (2002) 30 (3): A66.
The contrasting IgG-binding interactions of human and herpes simplex virus Fc receptors
Biochem Soc Trans (2002) 30 (3): A66.
Novel antibody therapeutics for treatment of cancer and inflammation
Biochem Soc Trans (2002) 30 (3): A67.
Formatting antibody fragments to mediate specific therapeutic functions
Biochem Soc Trans (2002) 30 (3): A68.
Amino acid sequence requirements in the human IgAl hinge for cleavage by streptococcal IgAl proteases
Biochem Soc Trans (2002) 30 (3): A68.
Red blood cells (RBC) coated with IgG anti-D bind transforming growth factor-beta (TGF-beta)
Biochem Soc Trans (2002) 30 (3): A68.
Neurodegeneration
Characterisation of thermodynamic diversity between TSE agent strains
Biochem Soc Trans (2002) 30 (3): A69.
An investigation into the mechanism of toxicity of amyloid-forming proteins and peptides
Biochem Soc Trans (2002) 30 (3): A69.
Heparan sulphate binds the aspartic protease β-Secretase and regulates cleavage of APP
Biochem Soc Trans (2002) 30 (3): A69.
Does pentosan polysulphate have prophylactic potential for transmissible spongiform encephalopathies?
C. F. Farquhar; I. McConnell; J. Graham; S. Cumming; G. R. Barclay; A. Boyle; M. L. Turner; M. E. Bruce
Biochem Soc Trans (2002) 30 (3): A70.
Chronic nicotine treatment reduces beta-amyloidosis
J. Court; E. Hellstrom-Lindhal; M. Lee; M. Johnson; M. Mousavi; R. Hall; E. Perry; I. Bednar; A. Nordberg
Biochem Soc Trans (2002) 30 (3): A70.
An investigation in changes in gene regulation and subsequent signal transduction activation after ischemic stroke
Biochem Soc Trans (2002) 30 (3): A71.
Aminolevulic acid transport in murine mammary adenocarcinoma cells
Biochem Soc Trans (2002) 30 (3): A71.
The effect of NO-donors on sulfur amino acids produced by rat hepatoma cells
Biochem Soc Trans (2002) 30 (3): A72.
Pharmacokinetics of PPIX synthesis induced by administration of ALA and He-ALA
Biochem Soc Trans (2002) 30 (3): A72.
Genotype/phenotype correlation in patients with Erythropoietic Protoporphyria
Biochem Soc Trans (2002) 30 (3): A72.
Preliminary studies about the effect of acute and chronic ALA intoxication in brain mice
Biochem Soc Trans (2002) 30 (3): A73.
Spectroscopic characterisation of Cytochrome cbb3 oxidase from Pseudomonas stutzeri
Biochem Soc Trans (2002) 30 (3): A73.
An investigation into the mechanism of SirB from Bacillus megaterium - a sirohydrochlorin ferrochelatase
Biochem Soc Trans (2002) 30 (3): A73.
Cloning, expression and characterisation of ALAD from the deep-sea fish Coryphaenoides armatus
Biochem Soc Trans (2002) 30 (3): A73.
Haem A synthesis in Bacillus subtilis: stucture and function of CtaA
Biochem Soc Trans (2002) 30 (3): A74.
Cobalamin (Vitamin B12) biosynthesis in Rhodobacter capsulatus.
Biochem Soc Trans (2002) 30 (3): A74.
Inhibition of cytochrome c oxidase by nitrite and nitric oxide:reversible and irreversible
Biochem Soc Trans (2002) 30 (3): A74.
Spectroscopic characterisation of the substrate binding properties of NADPH:protochlorophyllide oxidoreductase (POR)
Biochem Soc Trans (2002) 30 (3): A74.
Two enzymes for oxygen-dependent and independent decarboxylation of coproporphyrinogen III during bacterial tetrapyrrole biosynthesis
Biochem Soc Trans (2002) 30 (3): A75.
Mechanistic insights into flavocytochrome c3, the soluble fumarate reductase from Shewanella frigidimarina
Biochem Soc Trans (2002) 30 (3): A75.
The coupling of ATP hydrolysis to metal ion insertion into porphyrins by magnesium chelatase
Biochem Soc Trans (2002) 30 (3): A75.
The role of membrane bound tetraheme CymA in the anaerobic respiration of Shewanella oneidensis MR-1
Biochem Soc Trans (2002) 30 (3): A75.
Novel respiratory flavocytochromes of Shewanella oneidensis MR-1
Biochem Soc Trans (2002) 30 (3): A76.
Spectral properties of bacterial nitric oxide reductase
Sarah J. Field; Louise Prior; M. Dolores Roldán; Myles R. Cheesman; Andrew J. Thomson; Stephen Spiro; Julea Butt; Nicholas J. Watmough; David J. Richardson
Biochem Soc Trans (2002) 30 (3): A76.
Studies on 5-aminolaevulinic acid dehydratase from Pisum sativum
Biochem Soc Trans (2002) 30 (3): A76.
Studies on human recombinant 5-aminolaevulinic acid dehydratase and human recombinant porphobilinogen deaminase
Biochem Soc Trans (2002) 30 (3): A77.
The expression, purification and steady state analysis of magnesium protoporphyrin IX methyltransferase from Synechocystis PCC6803
Biochem Soc Trans (2002) 30 (3): A77.
20S Proteasomal degradation of α-synuclein does not generate the non-β-amyloid plaque component (NAC)
Biochem Soc Trans (2002) 30 (3): A77.
Inhibition of Toxicity and protofibril formation in the β-amyloid peptide β(25–35) using N-Methylated derivatives
Biochem Soc Trans (2002) 30 (3): A78.
Chronic nicotine treatment reduces beta-amyloidosis
J. Court; E. Hellstrom-Lindhal; M. Lee; M. Johnson; M. Mousavi; R. Hall; E. Perry; I. Bednar; A. Nordberg
Biochem Soc Trans (2002) 30 (3): A78.
Proteolytic processing of the amyloid precursor protein by α-secretase
Biochem Soc Trans (2002) 30 (3): A78.
Heparan sulphate binds the aspartic protease β-secretase and regulates cleavage of APP
Biochem Soc Trans (2002) 30 (3): A78.
Altered processing of the Alzheimer's amyloid precursor protein in human neuroblastoma cells expressing the prion protein
Biochem Soc Trans (2002) 30 (3): A79.
An N-methylated analogue inhibits α-synuclein(68–78) aggregation
Biochem Soc Trans (2002) 30 (3): A79.
Role of the transmembrane form of the prion protein in neurodegeneration
Biochem Soc Trans (2002) 30 (3): A79.
Characterisation of thermodynamic diversity between TSE agent strains
Biochem Soc Trans (2002) 30 (3): A79.
Polyglutamine conformation in GST-polyglutamine fusion proteins
Biochem Soc Trans (2002) 30 (3): A80.
Amyloid fibril formation by human stefin B; influence of solvent composition, trifluoroethanol and temperature
Biochem Soc Trans (2002) 30 (3): A80.
A correlation study of human serum Aβ1–42 and serum cholesterol measurements
Biochem Soc Trans (2002) 30 (3): A81.
Cyclodextrin dimers and trimers inhibit the aggregation of β-amyloid
Biochem Soc Trans (2002) 30 (3): A81.
A beta-site amyloid precursor protein cleaving enzyme (BACE) assay
Biochem Soc Trans (2002) 30 (3): A81.
Does pentosan polysulphate have prophylactic potential for transmissible spongiform encephalopathies?
C. F. Farquhar; I. McConnell; J. Graham; S. Cumming; R. Prescott; G. R. Barclay; A. Boyle; M. L. Turner; M. E. Bruce
Biochem Soc Trans (2002) 30 (3): A81.
New analytical methods for the study of protein aggregation in real time
Biochem Soc Trans (2002) 30 (3): A82.
What constitutes infectivity in Transmissible Spongiform Encephalopathy disease?
Biochem Soc Trans (2002) 30 (3): A82.
Characterisation of amyloid fibrils formed from β-lactoglobulin
Biochem Soc Trans (2002) 30 (3): A83.
Molecular characterization of protein interactions essential for neurotransmitter exocytosis: munc18 and mint
Biochem Soc Trans (2002) 30 (3): A83.
Haem oxygenase/nitric oxide synthase interaction: a role in neurodegeneration?
Biochem Soc Trans (2002) 30 (3): A84.
An investigation in changes in gene regulation and subsequent signal transduction activation after ischemic stroke
Biochem Soc Trans (2002) 30 (3): A84.
Molecular and cellular characterisation of the Prion-like protein Doppel
Biochem Soc Trans (2002) 30 (3): A84.
An investigation into the mechanism of toxicity of amyloid-forming proteins and peptides
Biochem Soc Trans (2002) 30 (3): A85.
SOD1 aggregation in familial amyotrophic lateral sclerosis (FALS)
Biochem Soc Trans (2002) 30 (3): A85.
Lessons from the Type II Family of G-Protein-Coupled Receptors: Ligands, Receptor Structure and Function
Adenylyl cyclase 9: biochemical and pharmacological characterisation of recombinantly expressed ‘active core’
Biochem Soc Trans (2002) 30 (3): A86.
Pharmacology and desensitisation of the human ramp3 and rat crlr combination
Biochem Soc Trans (2002) 30 (3): A87.
Specific interaction between ARF6 and the Hop-1 intracellular loop 3 domain of the human PAC 1 receptor
Biochem Soc Trans (2002) 30 (3): A87.
Mitogenic signalling via the parathyroid hormone-related protein receptor
Biochem Soc Trans (2002) 30 (3): A87.
Selective regulation of secretin receptor responsiveness by PKA and GRK6
Biochem Soc Trans (2002) 30 (3): A87.
Interaction of calmodulin with the intracellular C-tails of metabotropic glutamate receptors assayed with the yeast two-hybrid system
Biochem Soc Trans (2002) 30 (3): A88.
Transcriptional regulation of the human CRLR in microvascular endothelial cells
Biochem Soc Trans (2002) 30 (3): A89.
In vivo association of 14-3-3 isoforms with mammalian origins of DNA replication
Biochem Soc Trans (2002) 30 (3): A89.
Use of cerebrospinal fluid 14-3-3 analysis in the diagnosis of sporadic and variant Creutzfeldt-Jakob disease
Biochem Soc Trans (2002) 30 (3): A90.
Approaches to study the structure and function of tomato 14-3-3 protein isoforms
Biochem Soc Trans (2002) 30 (3): A90.
Isolation of a member of the 14-3-3 gene family from a marine alga, Fucus vesiculosus
Biochem Soc Trans (2002) 30 (3): A90.
Temporal nuclear translocation of PKC Isoenzymes during adipocyte differentiation
Biochem Soc Trans (2002) 30 (3): A90.
Analysis of 14-3-3 isoforms in the lateral geniculate nucleus in murine brain
Biochem Soc Trans (2002) 30 (3): A91.
Early changes in protein kinase c and tubulinα expression in rat liver by phenobarbital
Biochem Soc Trans (2002) 30 (3): A91.
IGF-1 induces phosphorylation of two novel residues of FKHR
Graham Rena; Yvonne L. Woods; Alan R. Prescott; Mark Peggie; Terry G. Unterman; Michayla R. Williams; Philip Cohen
Biochem Soc Trans (2002) 30 (3): A91.
Anti-malaria immune effector mechanisms recruited by human IgG1 and IgA1 monoclonal antibodies
Biochem Soc Trans (2002) 30 (3): A92.
Amino acid sequence requirements in the human IgA1 hinge for cleavage by streptococcal IgA1 proteases
Biochem Soc Trans (2002) 30 (3): A92.
Chimeric human antibodies directed against a major surface antigen of Pseudomonas aeruginosa
Biochem Soc Trans (2002) 30 (3): A92.
Red blood cells (RBC) coated with IgG anti-D bind transforming growth factor-beta (TGF-beta)
Biochem Soc Trans (2002) 30 (3): A93.
MISCELLANEOUS
Kaempferol metabolism by rat hepatocytes cultured on different collagen substrates
Biochem Soc Trans (2002) 30 (3): A94.
The role of adrenomedullin (AM) and pro-adrenomedullin N-terminal 20 peptide (PAMP) in osteoblast metabolism
Biochem Soc Trans (2002) 30 (3): A94.
Hepatic heme-oxygenase and oxidative stress during short-term treatment with DAB
Biochem Soc Trans (2002) 30 (3): A94.
Scrapie spreads from the gastrointestinal tract to the CNS along autonomic and sensory relays of the peripheral nervous system
Biochem Soc Trans (2002) 30 (3): A95.
Binding of prion proteins to lipid membranes and implications for prion conversion
Biochem Soc Trans (2002) 30 (3): A95.
γ-secretase enzyme specificity toward cleavage of amyloid precursor protein and Notch
Biochem Soc Trans (2002) 30 (3): A95.
Overexpression, purification and characterisation of the N-terminal domain of the glucagon-like peptide-1 receptor
Biochem Soc Trans (2002) 30 (3): A96.
Alanine scan of the first extracellular loop of the glucagon-like peptide-1 receptor
Biochem Soc Trans (2002) 30 (3): A96.
