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October 2001
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ISSN 0300-5127
EISSN 1470-8752
In this Issue
674th Trinity College, Dublin Signalling Homeostasis
DNA Damage Signalling and Apoptosis
DNA damage signalling and NFκB: mechanisms of activation and implications for death
Biochem Soc Trans (2001) 29 (5): A92.
Uncovering BRCA1 regulated signalling pathways by microarray based expression profiling
Biochem Soc Trans (2001) 29 (5): A93.
Pyrrolo-1,5-benzoxazepines: A new class of apoptotic agents
P.M. Zisterer; M.M. McGee; G. Campiani; A. Rumunno; C. Fattorusso; V. Nacci; M. Lawler; D.C. Williams
Biochem Soc Trans (2001) 29 (5): A94.
Neurotransmitter Transporters: Molecular Mechanism and Regulation
Molecular characterisation of substrate binding sites in the glutamate transporter family
Biochem Soc Trans (2001) 29 (5): A95.
Molecular cloning and characterization of hemicholinium-3-sensitive choline transporters
Biochem Soc Trans (2001) 29 (5): A95.
Molecular determinants involved in the asymmetrical distribution of glycine transporters in polarised cells
Biochem Soc Trans (2001) 29 (5): A97.
Mitochondrial Uncoupling Proteins
Life without UCP1
Jan Nedergaard; Valeria Golozoubova; Anita Matthias; Irina G. Shabalina; Anders Jacobsson; Barbara Cannon
Biochem Soc Trans (2001) 29 (5): A97.
The function of UCP1 homologues
M.D. Brand; M.B. Jekabsons; D. Roussel; J. St-Pierre; S. Cadenas; J.C. Clapham; J.A. Harper; J.A. Stuart; K. Echtay
Biochem Soc Trans (2001) 29 (5): A98.
Ucp3 expression and function:Studies in transgenic mice and human muscle
Biochem Soc Trans (2001) 29 (5): A98.
Signal Transduction During Innate and Adaptive Immunity
Dimerization of the CD45 RPTPase inhibits its function in vivo and is necessary in order to prevent autoimmunity
Biochem Soc Trans (2001) 29 (5): A102.
Signal transduction downstrean of PI 3-kinase
Ricardo M. Biondi; Maria Deak; Simon Dowler; Wendy Kimber; Margaret Lawlor; Christine Thomas; Daan Van Aalton; Dario R. Alessi
Biochem Soc Trans (2001) 29 (5): A104.
Teaching Practical Skills to 21st Century Biochemists
Specialist and refresher courses for the practising biochemist: the importance of continuing education
Biochem Soc Trans (2001) 29 (5): A107.
Enzymes That Regulate Lipid Metabolism In Cell Signalling
Coordinate regulation of growth factor receptors and lipid phosphate phosphatase-1 controls cell activation by exogenous lysophosphatidate
Biochem Soc Trans (2001) 29 (5): A108.
Regulation of phospholipase C-γ2 and phosphoinositide 3-kinase pathways by adaptor molecules in B lymphocytes
Biochem Soc Trans (2001) 29 (5): A109.
Signalling via PI3-kinases
P.T. Hawkins; L. Stephens; H. Welch; C. Ellson; S. Gobert; A.B. Holmes; J.W. Thuring; M.A. Cooper; Z-Y Lim; P. Tempst; H. Erdjument-Bromage; A. Grewal
Biochem Soc Trans (2001) 29 (5): A109.
Type I Interferon Inhibit Neutrophil Apoptosis via a PI-3 kinase Dependent Signaling Pathway
Biochem Soc Trans (2001) 29 (5): A110.
Xanthine oxidoreductase activity in synovial fluid from patients with rheumatoid arthritis
Biochem Soc Trans (2001) 29 (5): A110.
Cloning, characterisation and analysis of endonuclease V from three different classes of bacteria
Biochem Soc Trans (2001) 29 (5): A111.
Expression and localisation of a CLIC (Chloride Intracellular Channel) protein fused to green fluorescent protein
Biochem Soc Trans (2001) 29 (5): A112.
Relationship between variable Bcr-Abl expression levels and drug resistance: Role of AKT/Protein Kinase B pathway
Biochem Soc Trans (2001) 29 (5): A112.
The role of tyrosine phosphorylation in TNFα-induced apoptosis of Human Umbilical Vein Endothelial Cells (HUVECs)
Biochem Soc Trans (2001) 29 (5): A113.
Studies on induction of differentiation in mouse embryonic stem cells using retinoic acid and dimethyl sulphoxide
Biochem Soc Trans (2001) 29 (5): A115.
The neuronal apoptosis inhibitory protein (NAIP) is a membrane-associated cytoplasmic protein in rabbit brain
Biochem Soc Trans (2001) 29 (5): A116.
The effects of protein kinase inhibitors on Type I diabetic serum-induced BRIN BD11 pancreatic beta-cell cytotoxicity
Biochem Soc Trans (2001) 29 (5): A116.
A human cell culture system for studying post-translational regulation of p53 at physiological levels
Biochem Soc Trans (2001) 29 (5): A116.
Transient Jun N-terminal kinase (JNK) activation and suppression of apoptosis by IGF-I
Biochem Soc Trans (2001) 29 (5): A117.
The type of cell death induced by MPP+ is both concentration and time dependant
Biochem Soc Trans (2001) 29 (5): A117.
Domain requirements for IGF-1 receptor and insulin receptor tyrosine kinase activity
Biochem Soc Trans (2001) 29 (5): A117.
Impairments in IGF-1-PKB signal transduction in Alzheimer's disease brain
Biochem Soc Trans (2001) 29 (5): A118.
Attenuation of G-protein coupled receptor activated p42/p44 mitogen activated protein kinase by lipid phosphate phosphatases 1,1a and 2
Biochem Soc Trans (2001) 29 (5): A118.
Vav1 is required for platelet aggregation to threshold concentrations of Glycoprotein VI agonist, independent of phospholipase C and Rac
Biochem Soc Trans (2001) 29 (5): A118.
Characterisation of Phenylalanine Dehydrogenase with chemically synthesised non-natural amino acids
Biochem Soc Trans (2001) 29 (5): A119.
Examination of coenzyme specificity in Clostridial glutamate dehydrogenase by site-directed mutagenesis
Biochem Soc Trans (2001) 29 (5): A119.
The isolation and characterisation of a cold-adapted metallo-alkaline phosphatase from the Arctic psychrophile strain PA-43
Biochem Soc Trans (2001) 29 (5): A119.
RT-PCR evidence for the expression of UCP-2 in Spleen and a murine macrophage cell line (J774)
Biochem Soc Trans (2001) 29 (5): A119.
Artefactual uncoupling following UCP3 expression in yeast mitochondria
Biochem Soc Trans (2001) 29 (5): A120.
Skeletal Muscle Uncoupling Protein 3 Expression Following Endurance Swimming Training in Mice
Biochem Soc Trans (2001) 29 (5): A120.
UCP2, expressed at endogenous levels, mediates mitochondrial proton leak in mammalian cells
Biochem Soc Trans (2001) 29 (5): A120.
Relationship between uncoupling proteins and mitochondrial proton leak in multiple tissues of arctic ground squirrels
Biochem Soc Trans (2001) 29 (5): A121.
Effect of chronic leptin administration on UCP1 expression in neonatal lambs
Biochem Soc Trans (2001) 29 (5): A121.
Effect of administration of phosphorolated prolactin (p-prl) on voltage dependent anion channel (vdac) and cytochrome c abundance in liver of pregnant rats
Biochem Soc Trans (2001) 29 (5): A121.
Overfeeding adolescent sheep affects uncoupling protein-1 (UCP-1) but not voltage dependent anion channel (VDAC) abundance in fetal perirenal adipose tissue
Biochem Soc Trans (2001) 29 (5): A121.
Uncoupling protein 2 expression and coenzyme Q content of spleen and lung-effects of neonatal endotoxaemia
Biochem Soc Trans (2001) 29 (5): A122.
Effects of maternal nutrient restriction on ovine fetal uncoupling protein-1 expression
Biochem Soc Trans (2001) 29 (5): A122.
Systematic investigation of the second repeat of the uncoupling protein UCP1 by replacement with divergent UCP2 motifs
Biochem Soc Trans (2001) 29 (5): A123.
The effect of Y253F on the activity of the plant alternative oxidase in Schizosaccharomyces pombe mitochondria
Biochem Soc Trans (2001) 29 (5): A123.
Amino acid sequencing and possible cloning of a new proline specific peptidase from bovine serum
Biochem Soc Trans (2001) 29 (5): A125.
Significant raise of IgM and IgG anti-(xanthine oxidoreductase) antibodies in synovial fluid of rheumatoid arthritis patients
Biochem Soc Trans (2001) 29 (5): A125.
A family of proteins related to spatzle, the Tol receptor ligand are encoded in the Drosophila genome
Biochem Soc Trans (2001) 29 (5): A126.
Requirement for CD28 co-stimulation is lower in SHP-1 deficient T cells
R.J. Matthews; J.G. Sathish; K.G. Johnson; E.G. LeRoy; K.J. Fuller; M.B. Hallett; P. Brennan; L.K. Borysiewicz; M.J. Sims
Biochem Soc Trans (2001) 29 (5): A126.
Signal transduction mechanisms generating T-cell leukaemias in CD45-deficient mutant Lck mice
Biochem Soc Trans (2001) 29 (5): A126.
The tyrosine phosphatase, SHP-1, modulates proliferation and apoptotic responses in the interleukin-3 dependant cell line Ba/F3
Biochem Soc Trans (2001) 29 (5): A126.
CD28 upregulates expression of EphA3 in Jurkat cells through the IGF-I receptor
Biochem Soc Trans (2001) 29 (5): A127.
Regulation of IL-1 induced NF-κB signalling by Tollip involves both receptor complex components TRAF6 and MyD88
Biochem Soc Trans (2001) 29 (5): A127.
Tumor-expressed Fas ligand suppresses IL-2 production in tumor-infiltrating lymphocytes
Biochem Soc Trans (2001) 29 (5): A127.
Oxidation decreases the anti-inflammatory activity of secretory leucoprotease inhibitor
Biochem Soc Trans (2001) 29 (5): A128.
The Jurkat cell line has constitutively active PI3K/PKB SIgnalling: effect of inducible expression of a membrane-localised SHIP construct
Biochem Soc Trans (2001) 29 (5): A128.
GPVI signalling in glycosphingolipid enriched membrane domains (GEMs)
Biochem Soc Trans (2001) 29 (5): A129.
Acylation of Lysophosphatidylcholine is Crucial to the Monocyte Response to LPS
Biochem Soc Trans (2001) 29 (5): A129.
Vav-2 signalling participates in the humoral immune response and B cell maturation
Biochem Soc Trans (2001) 29 (5): A129.
The putative GTPase activating protein IIP-1 functions antagonistically to Ras in the regulation of Interleukin-1 signalling
Biochem Soc Trans (2001) 29 (5): A130.
Role of the cytoplasmic tyrosine phosphatase SHP-2 in haemopoietic cells following IL-3 stimulation
Biochem Soc Trans (2001) 29 (5): A130.
Mal (MyD88 adapter-like) is a novel Toll IL-1 receptor (TIR) domain-containing adapter which recruits IRAK-2 during Toll-like receptor-4 signal transduction
K.A. Fitzgerald; A.G. Bowie; E.M. Palsson-McDermott; A. Dunne; P. Gray; M.T. Harte; C.A. Jefferies; A.S. Mansell; D. McMurray; D.E. Smith; J.E. Sims; T.A. Bird; L.A.J. O'Neill
Biochem Soc Trans (2001) 29 (5): A132.
CXCR3-mediated signal transduction events in T-blasts in response to IP-10 and ITAC stimulation
Biochem Soc Trans (2001) 29 (5): A132.
Investigation into the activation status of PKC isoforms β1, δ and θ in a Jurkat T cell line using phospho-specific antibodies
Biochem Soc Trans (2001) 29 (5): A133.
CCR4-mediated signal transduction events in CCR4 transfected CHO cells in response to MDC stimulation
Biochem Soc Trans (2001) 29 (5): A134.
Dichloropropionanilide (DCPA) down regulates T cell IL-2 production by interfering with the binding of key transcription factors
Biochem Soc Trans (2001) 29 (5): A134.