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November 1991
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ISSN 0300-5127
EISSN 1470-8752
In this Issue
639th Meeting
Communication
Ultrastructural characterisation of normal and pathological human scleral proteoglycans
Biochem Soc Trans (1991) 19 (4): 350S.
Mucins synthesized in organ culture of human conjuctival tissue
Biochem Soc Trans (1991) 19 (4): 352S.
Proteoglycan-collagen interactions in chronic superficial keratitis in the dog
Biochem Soc Trans (1991) 19 (4): 353S.
Differential effect of oxygen supply and lactate concentration on keratan sulphate and glycoseminoglycuronan production in bovine cornea
Biochem Soc Trans (1991) 19 (4): 354S.
Kinetic analysis of halothane induced Ca2+ release from isolated heavy sarcoplasmic reticulum
Biochem Soc Trans (1991) 19 (4): 355S.
An alternative interpretation of multiple-affinity agonist binding to ß-adrenoceptors
Biochem Soc Trans (1991) 19 (4): 357S.
Stimulation of prostaglandin E2 binding to a murine macrophage cell line (P388D1) by insulin
Biochem Soc Trans (1991) 19 (4): 358S.
Binding saturation analysis of inositol-1,4,5-trisphosphate in suspension cultures of lucerne cells
Biochem Soc Trans (1991) 19 (4): 359S.
An assessment of the efficacy of anti-integrin α subunit monoclonal antibody production using affinity purified β1-integrin dimers as immunogen
Biochem Soc Trans (1991) 19 (4): 361S.
Relationship between the secretion of cysteine proteinases and their inhibitors and malignant potential
Biochem Soc Trans (1991) 19 (4): 362S.
Effect of oxygen tension on 35S-glycosaminoglycan synthesis and UDP-sugar pool size in articular cartilage
Biochem Soc Trans (1991) 19 (4): 364S.
The aromatic zipper: A model for the initial trimerization event in collagen folding
Biochem Soc Trans (1991) 19 (4): 365S.
Use of the polymerase chain reaction to amplify and clone α-chains of bovine collagen IV
Biochem Soc Trans (1991) 19 (4): 366S.
Kidney levels of mRNA encoding S and B2 laminin and α1(IV) collagen in diabetic rats fed an aldose reductase inhibitor
Biochem Soc Trans (1991) 19 (4): 367S.
Maintenance of collagen IV expression by bovine retinal pericytes isolated directly onto Matrigel film
Biochem Soc Trans (1991) 19 (4): 368S.
Effects of hyperglycaemic conditions on basement membrane gene expression in cultured cells
Biochem Soc Trans (1991) 19 (4): 369S.
Recombinant human and dog procollagenases Purification and characterisation
Biochem Soc Trans (1991) 19 (4): 371S.
Purification of recombinant dog tissue inhibitor of etalloproteinases
Biochem Soc Trans (1991) 19 (4): 372S.
T-cell responses to human cartilage antigens in patients with inflammatory joint disease
Biochem Soc Trans (1991) 19 (4): 378S.
Types II, VI and IX collagens in normal and osteoarthrotic human articular cartilage
Biochem Soc Trans (1991) 19 (4): 379S.
Severe Osteogenesis Imperfecta: Type 1 collagen abnormalities in 17 skin fibroblast cell lines
Biochem Soc Trans (1991) 19 (4): 382S.
Type VI collagen forms a structural association with hyaluronan in vivo
Biochem Soc Trans (1991) 19 (4): 384S.
A collagenase-sensitive glycoprotein identified in foetal bovine cell cultures
Biochem Soc Trans (1991) 19 (4): 385S.
Deglycosylation of cartilage proteoglycans and their T cell responses
Biochem Soc Trans (1991) 19 (4): 386S.
Isolation of calcium- binding proteins by immobilized metal affinity chromatography
Biochem Soc Trans (1991) 19 (4): 387S.
N.m.r. spectroscopy of Ca2+-heparin suggests delocalized binding of the cation
Biochem Soc Trans (1991) 19 (4): 390S.
A relationship between cation-induced changes in heparin optical rotation and heparin-cation association constants
Biochem Soc Trans (1991) 19 (4): 392S.
Optical rotation changes in chemically modified heparins as a guide to anionic groups involved in Ca2+ binding
Biochem Soc Trans (1991) 19 (4): 393S.
Carboxylate symmetric stretching frequencies and optical rotation shifts of heparin-cation complexes
Biochem Soc Trans (1991) 19 (4): 394S.
Effect of physiological pressure on the secretion of cysteine proteinases and their inhibitors from articular cartilage
Biochem Soc Trans (1991) 19 (4): 396S.
Analysis of kinetic parameters of cyclic nucleotide phosphodiesterase systems by fast atom bombardment tandem mass spectrometry
TERENCE J WALTON; JAMES I LANGRIDGE; JALAL A KHAN; ANDREA M EVANS; A GARETH BRENTON; DIPANKAR GHOSH; FRANK M HARRIS; RUSSELL P NEWTON
Biochem Soc Trans (1991) 19 (4): 397S.
Differential effect of Coxsackie B4 virus on murine pancreatic islet preproinsulin mRNA and glyceraldehyde-3-phosphate dehydrogenase mRNA
Biochem Soc Trans (1991) 19 (4): 398S.
The place of bioenergetics in the modular biochemistry course in the School of Biological Sciences at Manchester
Biochem Soc Trans (1991) 19 (4): 399S.
Indirect measurement of betaine - homocysteine methyltransferase activity using 1H nmr spectroscopy
Biochem Soc Trans (1991) 19 (4): 402S.
Evidence for a protein X-like domain at the N-terminus of the E1 component of the mammalian 2-oxoglutarate dehydrogenase complex
Biochem Soc Trans (1991) 19 (4): 403S.
COMPUTER SIMULATIONS OF THE EFFECT OF GLYCOSYLATON ON THE CONFORMATIONAL FREEDOM OF PEPTIDES
Biochem Soc Trans (1991) 19 (4): 405S.
Solid phase synthesis of monosaccharide-containing N-glycopeptides
Biochem Soc Trans (1991) 19 (4): 406S.
Proton gradient-dependent active transport of l-lactate in basal plasma membrane vesicles isolated from syncytiotrophoblast human placenta
Biochem Soc Trans (1991) 19 (4): 409S.
Comparison of inhibitory effects of lithium and magnesium on longitudinal smooth muscle contraction
Biochem Soc Trans (1991) 19 (4): 411S.
Application of approach to equilbrium analytical ultracentrifugation (Archibald method) to the determination of molecular weights of humic substances
Biochem Soc Trans (1991) 19 (4): 414S.
The preparation and characteristics of immunoliposomes for targeting to tumour cells (A 431)
Biochem Soc Trans (1991) 19 (4): 415S.
The preparation and characterisation of proteoliposomes for targeting to oral bacteria
Biochem Soc Trans (1991) 19 (4): 416S.
Inactivation of the nucleoside transporter of the human erythrocyte by dimethyl (2-hydroxy-5-nitrobenzyl) sulphonium bromide
Biochem Soc Trans (1991) 19 (4): 418S.
The Use of Nested PCR and Southern Blotting to Confirm the Presence of Actin in Plasmodium yoelli
Biochem Soc Trans (1991) 19 (4): 419S.
The effects of essential fatty acid supplementation on lithium absorption kinetics in guinea pig jejunum
Biochem Soc Trans (1991) 19 (4): 422S.
Effects of pancuronium and vecuronium on plasma levels of lactate dehydrogenase and creatine kinase in patients undergoing gynaecological surgery
Biochem Soc Trans (1991) 19 (4): 423S.
Generation and metabolism of Ins(1,4,5)P3 in SH-SY5Y human neuroblastoma cells: The regulatory role of Ca2+
Biochem Soc Trans (1991) 19 (4): 424S.
Isolation of microperoxisomes from human colonic mucosa
ADRIAN J. WOOD; ZULFIQAR A. MALIK; PRAMJIT S. TAPPIA; VALERIE POXON; ROGER GRACE; JOHN NEOPTOLEMOS; KEITH BURDETT; MARTIN J CONNOCK
Biochem Soc Trans (1991) 19 (4): 425S.
Menaquinone mediated free radical generation: a possible mutagenic mechanism
Biochem Soc Trans (1991) 19 (4): 426S.
Studies on a toxin produced by the cyanobacterium Phormidium persicinum
Biochem Soc Trans (1991) 19 (4): 428S.
Preparation of phenylalanine-deuterated, and totally 15N-enriched, calmodulins from Trypanosoma brucei, and its application in drug binding studies
Biochem Soc Trans (1991) 19 (4): 430S.
Effects of Methylazoxymethanol treatment on the GABAergic synaptosomes in the P2 fraction from developing mouse cerebellum
Biochem Soc Trans (1991) 19 (4): 431S.
The application of mass spectrometry in the study of labile natural products
Biochem Soc Trans (1991) 19 (4): 432S.
Effects of different de-endothelializing injuries to the rabbit carotid artery on glycosaminoglycan content and sulphonation during early wound healing
Biochem Soc Trans (1991) 19 (4): 435S.
Replication of the human immunodeficiency virus type 1 is inhibited in human cells with antisense RNA expression
Biochem Soc Trans (1991) 19 (4): 437S.
Replication of the human immunodeficiency virus type 1 is inhibited by the adeno-associated virus rep gene
Biochem Soc Trans (1991) 19 (4): 438S.
Integrin-dependent platelet recognition sites in collagen: Identification of a short platelet-reactive sequence in the type III-derived fragment α1(III)CB3
LAURENCE F. MORTON; LYNN S. ZIJENAH; ISOBEL Y. McCULLOCH; C. GRAHAM KNIGHT; MARTIN J. HUMPHRIES; MICHAEL J. BARNES
Biochem Soc Trans (1991) 19 (4): 439S.
Characterisation and regulation of angiotensin receptors in a rat intestinal epithelial cell line
Biochem Soc Trans (1991) 19 (4): 440S.
Biochemical changes in liver function due to prolonged administration of Co-protoporphyrin
Biochem Soc Trans (1991) 19 (4): 441S.
MONITORING OF THE IN SITU THYMINE PHOTO-ADDUCT USING OV IRRADIATED DNA ANTIBODY F(ab)2 FRAGMENT
Biochem Soc Trans (1991) 19 (4): 442S.
Catalase Activity in Cultured Human Retinal Pigment Epithelial Cells
Biochem Soc Trans (1991) 19 (4): 443S.
Correction
Cytochalasins potently inhibit glycogen synthesis in hepatocyte cultures by an indirect mechanism
Biochem Soc Trans (1991) 19 (4): 1125–1127.
G-proteins and the association of ligand/receptor complexes with the cytoskeleton in human neutrophils
Biochem Soc Trans (1991) 19 (4): 1127–1129.
Differences in basal and formyl-Met-Leu-Phe-stimulated F-actin content of human blood neutrophil subpopulations separated by continuous-flow electrophoresis
Biochem Soc Trans (1991) 19 (4): 1129–1130.
Microinjection of the Yersinia YopE cytotoxin in mammalian cells induces actin microfilament disruption
Biochem Soc Trans (1991) 19 (4): 1131–1132.
Glycoprotein Ib- and actin-binding regions in human platelet actin-binding protein
Biochem Soc Trans (1991) 19 (4): 1133–1134.
Differences in the content of actin-binding proteins in subcellular fractions prepared from Krebs II ascites cells
Biochem Soc Trans (1991) 19 (4): 1135–1136.
Changes in amounts of polysomes in free, cytoskeleton-bound and membrane-bound populations in Krebs II ascites cells subjected to different growth conditions
Biochem Soc Trans (1991) 19 (4): 1136–1137.
Difference in patterns of proteins isolated from polysomes in free, cytoskeleton-bound and membrane-bound fractions in MPC-II cells incubated with insulin
Biochem Soc Trans (1991) 19 (4): 1138–1139.
Inhibition by p-bromophenacyl bromide of microtubule assembly in vitro
Biochem Soc Trans (1991) 19 (4): 1140–1143.
Tubulin: tyrosine ligase activity in regenerating peripheral nerve
Biochem Soc Trans (1991) 19 (4): 1143–1146.
The largest neurofilament component assembles in non-neuronal cells (fibroblasts), but is not phosphorylated
Biochem Soc Trans (1991) 19 (4): 1147–1148.
Association of pp60c-src with the cytoskeleton upon platelet activation
Biochem Soc Trans (1991) 19 (4): 1150–1154.
Morphological changes in adherent cells induced by Clostridium difficile toxins
Biochem Soc Trans (1991) 19 (4): 1154–1160.
Restricted efflux of the type II isoform of cyclic AMP-dependent protein kinase in permeabilized rat hepatocytes
Biochem Soc Trans (1991) 19 (4): 1161–1162.
High-molecular-mass complexes of the regulatory subunits of cyclic AMP-dependent protein kinase
Biochem Soc Trans (1991) 19 (4): 1163–1165.
Joint Meeting of the Biochemical Societies of Denmark
Cytoskeleton: its Role in Cellular Function
Aspects of the evolution of the lamin/intermediate filament protein family: a current analysis of invertebrate intermediate filament proteins
Biochem Soc Trans (1991) 19 (4): 1021–1023.
Microtubule dynamic instability: some possible physical mechanisms and their implications
Biochem Soc Trans (1991) 19 (4): 1023–1028.
Cytoskeletal proteins in adherens-type cell-matrix junctions
David R. Critchley; Andrew Gilmore; Lance Hemmings; Paul Jackson; Alistair McGregor; Vasken Ohanian; Bipin Patel; Gillian Waites; Carlton Wood
Biochem Soc Trans (1991) 19 (4): 1028–1033.
p103 and A60: novel proteins of the neuronal membrane-associated cytoskeleton
Biochem Soc Trans (1991) 19 (4): 1042–1048.
Dynamic changes in neutrophil cytoskeleton during priming and subsequent surface stimulated functions
Biochem Soc Trans (1991) 19 (4): 1048–1055.
Generation of plasma membrane domains in polarized epithelial cells: role of cell-cell contacts and assembly of the membrane cytoskeleton
Biochem Soc Trans (1991) 19 (4): 1055–1059.
Desmosomal glycoproteins I, II and III: novel members of the cadherin superfamily
Grant N. Wheeler; Roger S. Buxton; Andrew E. Parker; Joachim Arnemann; David A. Rees; Ian A. King; Anthony I. Magee
Biochem Soc Trans (1991) 19 (4): 1060–1064.
Syndecan, a regulator of cell behaviour, is lost in malignant transformation
Biochem Soc Trans (1991) 19 (4): 1069–1072.
Developmental changes in expression of adhesion-mediating proteins in human aortic smooth muscle
Biochem Soc Trans (1991) 19 (4): 1072–1076.
Characterization of cytoplasmic proteins essential for exocytosis in chromaffin cells
Biochem Soc Trans (1991) 19 (4): 1090–1094.
Association of ribosomes with myofibrils and microfilaments: a role in the spatial organization of protein synthesis
Biochem Soc Trans (1991) 19 (4): 1103–1107.
Compartmentalization of polysomes into free, cytoskeletal-bound and membrane-bound populations
Biochem Soc Trans (1991) 19 (4): 1108–1111.
Keratin genes, epidermal differentiation and animal models for the study of human skin diseases
Biochem Soc Trans (1991) 19 (4): 1112–1115.
Reorganization and turnover of actin filament architectures in cell
Biochem Soc Trans (1991) 19 (4): 1120–1124.
639th Meeting
Enzymology in vivo
N.m.r. studies of muscle glycogen synthesis in normal and non-insulin-dependent diabetic subjects
Biochem Soc Trans (1991) 19 (4): 992–994.
A combined n.m.r. and molecular biological approach to studying enzymes in vivo
Biochem Soc Trans (1991) 19 (4): 997–1001.
Is there tight channelling in the tricarboxylic acid cycle metabolon?
Biochem Soc Trans (1991) 19 (4): 1002–1005.
Manipulating creatine kinase activity in transgenic mice to study control of energy metabolism
Biochem Soc Trans (1991) 19 (4): 1010–1014.
Bioenergetics — What Should We Teach and How Should We Teach it?
Using the bacterium, Paracoccus denitrificans and other ‘runaway mitochondria’ as classroom models for respiratory electron transport studies
Biochem Soc Trans (1991) 19 (4): 976–981.
Regulation of Retroviral Gene Expression
Biological Mass Spectrometry
The structural domains in the E2 component of the pyruvate dehydrogenase multienzyme complex from Bacillus stearothermophilus
Biochem Soc Trans (1991) 19 (4): 917–922.
Laser-desorption-ionization Fourier-transform ion-cyclotron-resonance (LDI-FT-ICR) mass spectrometry (m.s.) of bacterial oligosaccharides
Biochem Soc Trans (1991) 19 (4): 922–929.
Some biochemical applications of electrospray-magnetic sector mass spectrometry
Biochem Soc Trans (1991) 19 (4): 940–943.
Application of electrospray ionization mass spectrometry and tandem mass spectrometry in combination with capillary electrophoresis for biochemical investigations
Charles G. Edmonds; Joseph A. Loo; Rachel R. Ogorzalek Loo; Harold R. Udseth; Charles J. Barinaga; Richard D. Smith
Biochem Soc Trans (1991) 19 (4): 943–947.
The integration of mass spectrometry into the biochemistry laboratory
Biochem Soc Trans (1991) 19 (4): 948–953.
A comparison of electrospray-ionization m.s. and matrix-assisted laser desorption time-of-flight m.s. for the analysis of protein mixtures
Biochem Soc Trans (1991) 19 (4): 954–957.
Mass spectrometry software for biochemical analysis in electrospray and fast atom bombardment modes
Biochem Soc Trans (1991) 19 (4): 957–962.
Autocoid and Hormone Receptors: Rational Drug Design
Rational methods for site-directed drug design: novel approaches for the discovery of potential ligands
Biochem Soc Trans (1991) 19 (4): 883–887.
Intracellular recognition sites for inositol 1,4,5-triphosphate and inositol 1,3,4,5-tetrakisphosphate
Biochem Soc Trans (1991) 19 (4): 888–893.
Design of ligands for the glucocorticoid and progestin receptors
Biochem Soc Trans (1991) 19 (4): 901–908.
Tachykinin receptor antagonists and potential clinical applications at peripheral level
Biochem Soc Trans (1991) 19 (4): 909–912.
Cholecystokinin receptors: synthetic antagonists with selectivity for receptor subtypes and possible clinical applications
Biochem Soc Trans (1991) 19 (4): 913–915.
Biochemistry of the Eye
Structural and biochemical changes in the sclera of experimentally myopic eyes
Biochem Soc Trans (1991) 19 (4): 861–865.
Morphological and biochemical studies of the structure of the vitreous and the zonular fibres
Biochem Soc Trans (1991) 19 (4): 868–871.
Physical and biological properties of keratan sulphate proteoglycan
Biochem Soc Trans (1991) 19 (4): 871–876.
The Extracellular Matrix in Health and Disease
The human collagen X gene: complete primary sequence and re-expression in osteoarthritis
J. Terrig Thomas; Carl J. Cresswell; Bharat Rash; Judith Hoyland; Anthony J. Freemont; Michael E. Grant; Raymond P. Boot-Handford
Biochem Soc Trans (1991) 19 (4): 804–808.
Approaches to the design of anti-fibrotic drugs
Trevor J. Franklin; Neil J. Hales; Donna Johnstone; William B. Morris; C. Jane Cunliffe; Andrew J. Millest; George B. Hill
Biochem Soc Trans (1991) 19 (4): 812–815.
Structure and function of the fibril-associated collagens
Michel van der Rest; Elizabeth Aubert-Foucher; Bernard Dublet; Denise Eichenberger; Bernard Font; Denise Goldschmidt
Biochem Soc Trans (1991) 19 (4): 820–824.
Assembly of laminin isoforms by triple- and double-stranded coiled-coil structures
Biochem Soc Trans (1991) 19 (4): 839–843.