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Volume 18, Issue 1

February 1990

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Cover Image

Cover Image
Front Matter
Table of Contents

ISSN 0300-5127

EISSN 1470-8752

In this Issue

631st Meeting
12th Keilin Memorial Lecture

631st Meeting

Nutrient Regulation of Insulin Secretion

The role of the entero-insular axis in insulin secretion

LINDA M. MORGAN

Biochem Soc Trans (1990) 18 (1): 101–102.

View Articletitled, The role of the entero-insular axis in insulin secretion

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Intra-islet cellular interrelationships

VINCENT MARKS; KIM S. TAN; JOHN I. STAGNER; ELLIS SAMOLS

Biochem Soc Trans (1990) 18 (1): 103–104.

View Articletitled, Intra-islet cellular interrelationships

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Hexose recognition mechanisms in pancreatic B-cells

SIGURD LENZEN

Biochem Soc Trans (1990) 18 (1): 105–107.

View Articletitled, Hexose recognition mechanisms in pancreatic B-cells

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The fuel concept for insulin release: regulation of glucose phosphorylation in pancreatic islets

WILLY J. MALAISSE; FRANCINE MALAISSE-LAGAE; JOANNE RASSCHAERT; DAGMAR ZÄHNER; ABDULLAH SENER; DEWI R. DAVIES; EMILE VAN SCHAFTINGEN

Biochem Soc Trans (1990) 18 (1): 107–108.

View Articletitled, The fuel concept for insulin release: regulation of glucose phosphorylation in pancreatic islets

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ATP-sensitive K⁺ channels: a link between B-cell metabolism and insulin secretion

FRANCES M. ASHCROFT; PATRIK RORSMAN

Biochem Soc Trans (1990) 18 (1): 109–111.

View Articletitled, ATP-sensitive K+ channels: a link between B-cell metabolism and insulin secretion

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Cytoplasmic calcium ions and other signalling events in insulin secretion

CLAES B. WOLLHEIM; WILLIAM-F. PRALONG

Biochem Soc Trans (1990) 18 (1): 111–114.

View Articletitled, Cytoplasmic calcium ions and other signalling events in insulin secretion

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Protein kinase C and the regulation of insulin secretion

SIMON L. HOWELL; PETER M. JONES; SHANTA J. PERSAUD

Biochem Soc Trans (1990) 18 (1): 114–116.

View Articletitled, Protein kinase C and the regulation of insulin secretion

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Protein phosphorylation in the regulation of insulin secretion and biosynthesis

STEPHEN J. H. ASHCROFT; STEPHEN J. HUGHES

Biochem Soc Trans (1990) 18 (1): 116–118.

View Articletitled, Protein phosphorylation in the regulation of insulin secretion and biosynthesis

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Mechanisms of action of entero-insular hormones and neural input on the insulin secretory process

PER-OLOF BERGGREN; PATRIK RORSMAN; PER ARKHAMMAR; THOMAS NILSSON

Biochem Soc Trans (1990) 18 (1): 119–122.

View Articletitled, Mechanisms of action of entero-insular hormones and neural input on the insulin secretory process

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Biosynthesis and storage of insulin

JOHN C. HUTTON; ELAINE M. BAILYES; CHRISTOPHER J. RHODES; NICHOLAS G. RUTHERFORD; SUSAN D. ARDEN; PAUL C. GUEST

Biochem Soc Trans (1990) 18 (1): 122–124.

View Articletitled, Biosynthesis and storage of insulin

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Defective regulation of insulin secretion in diabetes and insulinoma

PETER R. FLATT

Biochem Soc Trans (1990) 18 (1): 124–127.

View Articletitled, Defective regulation of insulin secretion in diabetes and insulinoma

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Peroxisome Proliferation: Mechanisms and Biological Consequences

Protein targeting to peroxisomes

GILLIAN M. SMALL; ALFRED S. LEWIN

Biochem Soc Trans (1990) 18 (1): 85–87.

View Articletitled, Protein targeting to peroxisomes

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The peroxisome: functional properties in health and disease

GUY P. MANNAERTS; PAUL P. VAN VELDHOVEN

Biochem Soc Trans (1990) 18 (1): 87–89.

View Articletitled, The peroxisome: functional properties in health and disease

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Liver growth and early cellular changes in response to peroxisome proliferation

BETTINA KRAUPP; WOLFGANG HUBER; ROLF SCHULTE HERMANN

Biochem Soc Trans (1990) 18 (1): 89–92.

View Articletitled, Liver growth and early cellular changes in response to peroxisome proliferation

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Carcinogenicity of peroxisome proliferators: evaluation and mechanisms

JANARDAN K. REDDY

Biochem Soc Trans (1990) 18 (1): 92–94.

View Articletitled, Carcinogenicity of peroxisome proliferators: evaluation and mechanisms

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Hepatic peroxisome proliferation and oxidative stress

BRIAN G. LAKE; J. B. GRAY. TIM; ANDREW G. SMITH; JOHN G. EVANS

Biochem Soc Trans (1990) 18 (1): 94–97.

View Articletitled, Hepatic peroxisome proliferation and oxidative stress

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Induction of cytochrome P-450 IVA 1-mediated fatty acid hydroxylation: relevance to peroxisome proliferation

G. GORDON GIBSON; MARK N. MILTON; CLIFF R. ELCOMBE

Biochem Soc Trans (1990) 18 (1): 97–99.

View Articletitled, Induction of cytochrome P-450 IVA 1-mediated fatty acid hydroxylation: relevance to peroxisome proliferation

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Metbolic Control in Cancer

Signal transduction mechanisms in cancer

HANS GRUNICKE

Biochem Soc Trans (1990) 18 (1): 67–69.

View Articletitled, Signal transduction mechanisms in cancer

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Tyrosine kinase activities and neoplastic transformation

GEORGE FELICE; ANDREA R. HORVATH; STUART KELLIE

Biochem Soc Trans (1990) 18 (1): 69–72.

View Articletitled, Tyrosine kinase activities and neoplastic transformation

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Metabolic control of oncogene expression

EDITH OLÁH; REZSO EZER; WALTER GIARETTI; JOHN EBLE

Biochem Soc Trans (1990) 18 (1): 72–74.

View Articletitled, Metabolic control of oncogene expression

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Metabolic strategies in cancer chemotherapy

GEORGE WEBER

Biochem Soc Trans (1990) 18 (1): 74–78.

View Articletitled, Metabolic strategies in cancer chemotherapy

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Application of metabolic-control logic to the requirements for cell division

ERIC A. NEWSHOLME

Biochem Soc Trans (1990) 18 (1): 78–80.

View Articletitled, Application of metabolic-control logic to the requirements for cell division

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Tumour-host metabolic interrelationships

LEONARD A. SAUER; ROBERT T. DAUCHY

Biochem Soc Trans (1990) 18 (1): 80–82.

View Articletitled, Tumour-host metabolic interrelationships

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Metabolic effects in a murine cachexia model

MICHAEL J. TISDALE

Biochem Soc Trans (1990) 18 (1): 83–84.

View Articletitled, Metabolic effects in a murine cachexia model

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Post-Squalene Inhibition of Sterol Biosynthesis

Inhibition of squalene epoxidase and sterol side-chain methylation by allylamines

NEIL S. RYDER

Biochem Soc Trans (1990) 18 (1): 45–47.

View Articletitled, Inhibition of squalene epoxidase and sterol side-chain methylation by allylamines

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Inhibitors of 2,3-oxidosqualene lanosterol-cyclase as potential antifungal agents

SYNESE JOLIDON; ANNE-MARIE POLAK; PHILIPPE GUERRY; PETER G. HARTMAN

Biochem Soc Trans (1990) 18 (1): 47–48.

View Articletitled, Inhibitors of 2,3-oxidosqualene lanosterol-cyclase as potential antifungal agents

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Inhibition of sterol biosynthesis enzymes in vitro by analogues of high-energy carbocationic intermediates

ALAIN RAHIER; MARYSE TATON; PIERRE BENVENISTE

Biochem Soc Trans (1990) 18 (1): 48–52.

View Articletitled, Inhibition of sterol biosynthesis enzymes in vitro by analogues of high-energy carbocationic intermediates

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Plant sterol biosynthesis inhibitors: the 14-demethylation steps, their enzymology and inhibition

ALAIN RAHIER; MARYSE TATON

Biochem Soc Trans (1990) 18 (1): 52–56.

View Articletitled, Plant sterol biosynthesis inhibitors: the 14-demethylation steps, their enzymology and inhibition

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Mutation in cytochrome P-450-dependent 14α-demethylase results in decreased affinity for azole antifungals

HUGO VANDEN BOSSCHE; PATRICK MARICHAL; JOS GORRENS; DANNY BELLENS; HENRI MOEREELS; PAUL A. J. JANSSEN

Biochem Soc Trans (1990) 18 (1): 56–59.

View Articletitled, Mutation in cytochrome P-450-dependent 14α-demethylase results in decreased affinity for azole antifungals

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Inhibition of the sterol Δ¹⁴-reductase and Δ⁸→Δ⁷-isomerase in fungi

ANTONIUS KERKENAAR

Biochem Soc Trans (1990) 18 (1): 59–61.

View Articletitled, Inhibition of the sterol Δ14-reductase and Δ8→Δ7-isomerase in fungi

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Inhibitors of ergosterol biosynthesis as crop protection agents

BRIAN C. BALDWIN

Biochem Soc Trans (1990) 18 (1): 61–62.

View Articletitled, Inhibitors of ergosterol biosynthesis as crop protection agents

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Application of sterol synthesis inhibitors to investigate the sterol requirements of protozoa and plants

L. JOHN GOAD

Biochem Soc Trans (1990) 18 (1): 63–65.

View Articletitled, Application of sterol synthesis inhibitors to investigate the sterol requirements of protozoa and plants

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Small Group Teaching

Is small beautiful?

E. M. EVANS

Biochem Soc Trans (1990) 18 (1): 37–39.

View Articletitled, Is small beautiful?

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Biochemistry in the Oxford tutorial system: better teaching or wasted effort?

DONALD G. WILD

Biochem Soc Trans (1990) 18 (1): 39–40.

View Articletitled, Biochemistry in the Oxford tutorial system: better teaching or wasted effort?

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Keller Plan teaching in first year biochemistry

BRIAN C. STACE

Biochem Soc Trans (1990) 18 (1): 41–43.

View Articletitled, Keller Plan teaching in first year biochemistry

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Small-group teaching of biochemistry in the medical student laboratory

J. HYWEL THOMAS

Biochem Soc Trans (1990) 18 (1): 43–44.

View Articletitled, Small-group teaching of biochemistry in the medical student laboratory

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Development of Mixed-Function Oxidases

Evolution of the P450 gene superfamily and regulation of the murine Cyplal gene

ALVARO PUGA; DANIEL W. NEBERT

Biochem Soc Trans (1990) 18 (1): 7–10.

View Articletitled, Evolution of the P450 gene superfamily and regulation of the murine Cyplal gene

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From 14α-demethylase inhibitors in fungal cells to androgen and oestrogen biosynthesis inhibitors in mammalian cells

HUGO VANDEN BOSSCHE; GUSTAAF WILLEMSENS; DANNY BELLENS; IVAN ROELS; PAUL A. J. JANSSEN

Biochem Soc Trans (1990) 18 (1): 10–13.

View Articletitled, From 14α-demethylase inhibitors in fungal cells to androgen and oestrogen biosynthesis inhibitors in mammalian cells

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The cytochrome P450 IV family: constitutive and inducible haemoproteins

G. GORDON GIBSON

Biochem Soc Trans (1990) 18 (1): 14–15.

View Articletitled, The cytochrome P450 IV family: constitutive and inducible haemoproteins

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Cytochrome P-450 and oxidative metabolism in invertebrates

DAVID R. LIVINGSTONE

Biochem Soc Trans (1990) 18 (1): 15–19.

View Articletitled, Cytochrome P-450 and oxidative metabolism in invertebrates

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Structure, function and regulation of cytochrome P-450 forms in fish

JOHN J. STEGEMAN; BRUCE R. WOODIN; ROXANNA M. SMOLOWITZ

Biochem Soc Trans (1990) 18 (1): 19–21.

View Articletitled, Structure, function and regulation of cytochrome P-450 forms in fish

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Molecular genetics of the human cytochrome P-450 system

C. ROLAND WOLF; JOHN S. MILES; ALAN GOUGH; NIGEL K. SPURR

Biochem Soc Trans (1990) 18 (1): 21–24.

View Articletitled, Molecular genetics of the human cytochrome P-450 system

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Role of hormones in the control of mixed-function oxidases

PAUL SKETT

Biochem Soc Trans (1990) 18 (1): 24–26.

View Articletitled, Role of hormones in the control of mixed-function oxidases

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Regulation of steroid hydroxylase gene expression and steroid hormone biosynthesis

MICHAEL R. WATERMAN; JOHAN LUND; RAGNHILD AHLGREN; DONGAHI WU; EVAN R. SIMPSON

Biochem Soc Trans (1990) 18 (1): 26–28.

View Articletitled, Regulation of steroid hydroxylase gene expression and steroid hormone biosynthesis

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Cytochrome P-450 in the brain

MARIA STRÖMSTEDT; SHIN-ICHI HAYASHI; MARGARET WARNER; JAN-ÅKE GUSTAFSSON

Biochem Soc Trans (1990) 18 (1): 28–30.

View Articletitled, Cytochrome P-450 in the brain

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Molecular mechanisms of cytochrome P-450 gene regulation

PETER GOLDFARB

Biochem Soc Trans (1990) 18 (1): 30–32.

View Articletitled, Molecular mechanisms of cytochrome P-450 gene regulation

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Induction of cytochrome P450 I and its influences in chemical carcinogenesis

COSTAS IOANNIDES

Biochem Soc Trans (1990) 18 (1): 32–34.

View Articletitled, Induction of cytochrome P450 I and its influences in chemical carcinogenesis

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Future developments with the cytochromes P-450: promises for the applied chemical and medical sciences

RONALD W. ESTABROOK

Biochem Soc Trans (1990) 18 (1): 34–36.

View Articletitled, Future developments with the cytochromes P-450: promises for the applied chemical and medical sciences

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12th Keilin Memorial Lecture

Kinetics of ligand binding to haemoproteins

QUENTIN H. GIBSON

Biochem Soc Trans (1990) 18 (1): 1–6.

View Articletitled, Kinetics of ligand binding to haemoproteins

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Issues

Cover Image

631st Meeting

Nutrient Regulation of Insulin Secretion

Peroxisome Proliferation: Mechanisms and Biological Consequences

Metbolic Control in Cancer

Post-Squalene Inhibition of Sterol Biosynthesis

Small Group Teaching

Development of Mixed-Function Oxidases

12th Keilin Memorial Lecture

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