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June 1987
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ISSN 0300-5127
EISSN 1470-8752
Twenty-Third Colworth Medal Lecture
621st Meeting
Aspects of Lipid Metabolism in Relation to Health and Disease
Phosphatidylinositol-transfer protein and cellular phosphatidylinositol metabolism
Biochem Soc Trans (1987) 15 (3): 321–323.
Role of arachidonic acid metabolites in inflammatory and thrombotic responses
Biochem Soc Trans (1987) 15 (3): 324–326.
Arachidonic acid and leukotriene synthesis in relation to lung disease
Biochem Soc Trans (1987) 15 (3): 326–327.
The role of metabolites of arachidonic acid in the physiology and pathophysiology of muscle protein metabolism
Biochem Soc Trans (1987) 15 (3): 328–331.
Fatty acid transport in muscle: the role of fatty acid-binding proteins
Biochem Soc Trans (1987) 15 (3): 331–336.
Regulation of cholesterol metabolism in the liver in vivo and in vitro
Biochem Soc Trans (1987) 15 (3): 339–340.
Delivery of liposome-associated drugs to liver cells
GERRIT L. SCHERPHOF; HALBE H. SPANJER; JOHANNES T. P. DERKSEN; FOLKERT KUIPERS; ROEL J. VONK; TOOS DAEMEN; FRITS H. ROERDINK
Biochem Soc Trans (1987) 15 (3): 345–348.
Learning Aids
Computers in biochemical education: MBT-NET, the Liverpool Biochemistry/Microbiology teaching network
Biochem Soc Trans (1987) 15 (3): 349–351.
Audio-enhanced computer-assisted learning in science teaching
Biochem Soc Trans (1987) 15 (3): 351–354.
Interactive videodiscs in the life sciences: the use of ‘generic’ discs in the teaching of cell biology
Biochem Soc Trans (1987) 15 (3): 354–356.
Liver Heterogeneity: Intercellular and Intracellular
Intracellular and intercellular liver heterogeneity: an overview
Biochem Soc Trans (1987) 15 (3): 359–360.
Digitonin perfusion in the study of metabolic zonation of the rat liver: potassium as an intracellular concentration reference
Biochem Soc Trans (1987) 15 (3): 361–363.
Structural-functional organization of hepatic glutamine and ammonium metabolism
Biochem Soc Trans (1987) 15 (3): 369–372.
A comparative study of drug-metabolizing enzymes present in isolated rat liver parenchymal, Kupffer and endothelial cells
Biochem Soc Trans (1987) 15 (3): 372–373.
Methods in vitro for investigating the pathogenesis of alcoholic fatty liver disease in man
Biochem Soc Trans (1987) 15 (3): 374–375.
Communication
Human α-enolase and γ-enolase: purification and amino acid sequence comparisons
Biochem Soc Trans (1987) 15 (3): 377–378.
Properties of 6-phosphofructokinase from insect flight muscle
Biochem Soc Trans (1987) 15 (3): 378–379.
Theoretical properties of the steady-state distribution of H2PO-4 and HPO2-4 ions across the plasma membrane in glycolysing cells
Biochem Soc Trans (1987) 15 (3): 380–381.
Pitfalls in the interpretation of [32P]orthophosphate labelling in glycolysing cells
Biochem Soc Trans (1987) 15 (3): 381–382.
Selective measurement of orthophosphate concentration in microlitre volumes of cultured human cells
Biochem Soc Trans (1987) 15 (3): 382–383.
Purification and properties of 6-phosphofructo-2-kinase and fructose-2,6-bisphosphatase from rat hepatoma cells
Biochem Soc Trans (1987) 15 (3): 384–385.
Glycoprotein synthesis by human colon carcinoma cells in vitro and as xenografts in nude mice
Biochem Soc Trans (1987) 15 (3): 385.
A simple method for the calibration of recording fluorimeters by kinetic means in the study of NAD(P)+-dependent dehydrogenases
Biochem Soc Trans (1987) 15 (3): 386–387.
Is tissue β-hexosaminidase I2 the abnormally expressed form in acute lymphoblastic leukaemia?
Biochem Soc Trans (1987) 15 (3): 387–388.
The relationship between abnormal β-hexosaniinidase expression in leukaemia and changes in glycosylation
Biochem Soc Trans (1987) 15 (3): 388–389.
Uptake of heparan sulphate by rat rhabdomyosarcoma cells with different metastatic potentials
Biochem Soc Trans (1987) 15 (3): 389–390.
Glycosaminoglycan synthesis by aortic smooth muscle cells is modified by heparan sulphate, heparin and heparin-derived oligosaccharides
Biochem Soc Trans (1987) 15 (3): 390–391.
Demonstration of 9-O-lactyl-N-acetylneuraminic acid in human gastric aspirates
Biochem Soc Trans (1987) 15 (3): 391.
Radioactive substrates for the specific assay of glycoprotein glycosyl transfer and β-galactosidase activities
Biochem Soc Trans (1987) 15 (3): 392.
Detection of an O-acetyl-sialic acid esterase in faecal bacteria
Biochem Soc Trans (1987) 15 (3): 393.
The effect of glycosidases on the survival of red blood cells in circulation
Biochem Soc Trans (1987) 15 (3): 394.
Sialoglycoconjugates of gingiva in non-diabetic and diabetic dental patients
Biochem Soc Trans (1987) 15 (3): 395–396.
Sialyl compounds as acceptor substrates for fucosyltransferases in normal and leukaemic human granulocytes
Biochem Soc Trans (1987) 15 (3): 396.
Reassessment of fucosyltransferases in human leucocytes and platelets
Biochem Soc Trans (1987) 15 (3): 397.
N-Acetyl-β-d-glucosaminide α1 → 3fucosyltransferase purified from human neuroblastoma
Biochem Soc Trans (1987) 15 (3): 398–399.
Purification of β-d-(l-4)-N-acetylgalactosaminyltransferase from guinea-pig kidney
Biochem Soc Trans (1987) 15 (3): 399–400.
A new monoclonal antibody recognizing a Lewis-related structure
Biochem Soc Trans (1987) 15 (3): 400–401.
The ABH and Lewis antigens on the human intestinal hydrolases
Biochem Soc Trans (1987) 15 (3): 401–402.
Contact-induced lymphocyte lysosomal enzyme synthesis and transfer
Biochem Soc Trans (1987) 15 (3): 403–404.
The effect of fibre on the bacterial metabolism of bile acid in a continuous culture model of the large intestine
Biochem Soc Trans (1987) 15 (3): 405–406.
Faecal steroids and colorectal cancer: bile acid profiles in familial polyposis patients and siblings
Biochem Soc Trans (1987) 15 (3): 406–407.
A reversible Ca2+-dependent pore activated by oxidative stress in heart mitochondria
Biochem Soc Trans (1987) 15 (3): 408–409.
Apolipoprotein A abnormalities in patients with liver disease
Biochem Soc Trans (1987) 15 (3): 409–410.
Platelet function and tissue lipid peroxidation in rats fed polyunsaturated fatty acids
Biochem Soc Trans (1987) 15 (3): 410–411.
Synthesis of bile acids in Hep G2 cells: effect of substrate supply
Biochem Soc Trans (1987) 15 (3): 411–412.
Liposomes formed from polymerizable diacetylenic phospholipids and their potential as drug delivery systems
Biochem Soc Trans (1987) 15 (3): 413–414.
Synthesis of myo-inositol phosphates and analogues using a phosphite chemistry approach
Biochem Soc Trans (1987) 15 (3): 415–416.
Studies on the antioxidant activity of 5-lipoxygenase inhibitors
Biochem Soc Trans (1987) 15 (3): 416–417.
A comparison of zymosan and opsonized zymosan as stimuli for arachidonic acid metabolism in human leucocytes
Biochem Soc Trans (1987) 15 (3): 417–418.
Arachidonic acid analogues as inhibitors of phospholipase A2 activity
Biochem Soc Trans (1987) 15 (3): 418–419.
A radiometric assay for the measurement of phospholipase A2: comparison of different substrate lipids
Biochem Soc Trans (1987) 15 (3): 419–420.
Relationship between pseudocholinesterase and lipids in hyperlipoproteinaemia
Biochem Soc Trans (1987) 15 (3): 421–422.
Dietary cholesterol and bile acid synthesis in isolated rat hepatocytes
Biochem Soc Trans (1987) 15 (3): 422–423.
Temporal changes in the fatty acid composition of liver and plasma lipids in the male chicken after oestrogen administration
Biochem Soc Trans (1987) 15 (3): 423–424.
Changes in prostaglandin E excretion induced with linoleates and dihomo-γ-linolenic acid
Biochem Soc Trans (1987) 15 (3): 424–425.
Effect of inhibitors of the arachidonic acid cascade on muscle protein degradation
Biochem Soc Trans (1987) 15 (3): 425–426.
K+ depolarization markedly enhances carbachol-stimulated inositol 1,3,4,5-tetrakisphosphate production in cerebral cortex
Biochem Soc Trans (1987) 15 (3): 426–427.
Enzymes involved in adenosine metabolism in brown and white adipocytes
Biochem Soc Trans (1987) 15 (3): 427–428.
Enzymes of glycerolipid synthesis in brown and white adipocytes
Biochem Soc Trans (1987) 15 (3): 428–429.
Partial purification and characterization of rat brain myo-inositol-1-phosphatase
Biochem Soc Trans (1987) 15 (3): 429–430.
Lysosomal engorgement inhibits fluid-phase pinocytosis in macrophages
Biochem Soc Trans (1987) 15 (3): 432–433.
Inhibition of insulin degradation in isolated rat kidney tubules
Biochem Soc Trans (1987) 15 (3): 433–434.
A study of lysosomal membrane with monoclonal antibodies
MARIE-MONIQUE GONZE; SIMONE WATTIAUX-DE CONINCK; FRANCIS MAINFERME; JEAN-JACQUES LETESSON; ROBERT WATTIAUX
Biochem Soc Trans (1987) 15 (3): 436.
Antibodies as probes of the human erythrocyte glucose transporter
Biochem Soc Trans (1987) 15 (3): 436–437.
Reconstitution in vitro of events on the endocytic pathway for asialoglycoproteins in rat hepatocytes
Biochem Soc Trans (1987) 15 (3): 438–439.
Vitamin B12 transport through polarized monolayers of a colon carcinoma cell line
Biochem Soc Trans (1987) 15 (3): 439–440.
Release of iron from transferrin in the isolated endocytic vesicle
Biochem Soc Trans (1987) 15 (3): 442–443.
The effect of phorbol esters on receptor-mediated endocytosis of asialoglycoproteins by hepatocytes
Biochem Soc Trans (1987) 15 (3): 443–444.
Intracellular delivery and release of fluorescein from an acid-labile transferrin conjugate
JACINTA M. KEOGH-BENNETT; IAN T. MATTHEWS; JACQUELINE S. BEESLEY; FRANK PAUL; GLYNN WILSON; PETER W. TAYLOR
Biochem Soc Trans (1987) 15 (3): 444–445.
Receptor-mediated endocytosis in perfused rat livers pretreated with aflatoxin B1
Biochem Soc Trans (1987) 15 (3): 445–446.
Cell-to-cell transfer of lysosomal enzymes from lymphocytes to I-cell disease fibroblasts
Biochem Soc Trans (1987) 15 (3): 446–447.
Species variations in the hepatic and renal conjugation of benzoic acid with glycine or glucuronic acid
Biochem Soc Trans (1987) 15 (3): 451–452.
Effects of co-administration of polychlorinated biphenyls and the plasticizer di(2-ethylhexyl)phthalate on the liver and thyroid
Biochem Soc Trans (1987) 15 (3): 452–453.
Location of binding sites for monoclonal antibodies on cytochrome P-450c
Biochem Soc Trans (1987) 15 (3): 455.
Absorption and excretion of linear alkylbenzene sulphonates in rats
Biochem Soc Trans (1987) 15 (3): 456.
Isolation and characterization of rat renal proximal tubular cells
Biochem Soc Trans (1987) 15 (3): 457–458.
Changes in polyamine concentrations in human breast cancer cells in culture: the effect of serum type and 17β-oestradiol
Biochem Soc Trans (1987) 15 (3): 458–459.
A distinctive 30 base pair sequence in the 5′-flanking region of the CDC7 gene of yeast
Biochem Soc Trans (1987) 15 (3): 460–461.
Splicing of the SV40 small t intron is restricted by its size
Biochem Soc Trans (1987) 15 (3): 461–462.
Expression of a human phosphoglycerate kinase cDNA in Chinese hamster cells
Biochem Soc Trans (1987) 15 (3): 463.
Isolation of phosphoglycerate kinase genes from Chinese hamster cells
Biochem Soc Trans (1987) 15 (3): 463–464.
Inhibition of sarcoplasmic reticulum calcium pump by monoclonal antibodies
Biochem Soc Trans (1987) 15 (3): 464–465.
Effect of local anaesthetics on influx of Ca2+, Na+ and K+ into human isolated saphenous vein
Biochem Soc Trans (1987) 15 (3): 465–466.
The anti-histamine, Triludan, reduces the contraction produced by a skeletal muscle relaxant, atracurium, in rat isolated ileum
Biochem Soc Trans (1987) 15 (3): 466–467.
Neuronotrophic activity of adult human skeletal muscle extract on cultured rat spinal neurons
Biochem Soc Trans (1987) 15 (3): 467–468.
Toxic peptide from the blue-green alga Microcystis aeruginosa: effects on hepatocytes and thymocytes
Biochem Soc Trans (1987) 15 (3): 468–469.
The use of a personalized system of instruction for the teaching of enzymology
Biochem Soc Trans (1987) 15 (3): 469–470.
An analysis of student responses to a personalized system of instruction for teaching enzymology
Biochem Soc Trans (1987) 15 (3): 470–471.
The effects of carbamylation on the antigenicity of human immunoglobulin G probed with monoclonal antibodies
Biochem Soc Trans (1987) 15 (3): 472–473.
Inositol lipid turnover in isolated guinea-pig trachealis and lung parenchyma
Biochem Soc Trans (1987) 15 (3): 474.
Inhibition of antigen-induced release of eicosanoids from mast cells
Biochem Soc Trans (1987) 15 (3): 476.
Polyclonal antibodies to human plasma lecithin:cholesterol acyltransferase
Biochem Soc Trans (1987) 15 (3): 477–478.
Lysis of African trypanosomes by human plasma lipoproteins
Biochem Soc Trans (1987) 15 (3): 478–479.
Altered steroid hormone and prostaglandin metabolism during chlamydial infection in sheep
Biochem Soc Trans (1987) 15 (3): 479.
Evidence that sequential solubilization of the bile canalicular membrane occurs during the onset of bile acid-induced cholestasis
Biochem Soc Trans (1987) 15 (3): 480.
Pulmonary surfactant biosynthesis: studies in vivo and in vitro
Biochem Soc Trans (1987) 15 (3): 480–481.
Changes in the level of hepatic fatty acid-binding protein during development of the rat
Biochem Soc Trans (1987) 15 (3): 483–484.
The binding properties of rat liver fatty acid-binding protein
Biochem Soc Trans (1987) 15 (3): 484–485.
The modification of low-density lipoproteins by macrophages in relation to atherosclerosis
Biochem Soc Trans (1987) 15 (3): 485–486.
Functional heterogeneity of human plasma low-density lipoproteins
Biochem Soc Trans (1987) 15 (3): 486–487.
Purine-induced inhibition of lecithin: cholesterol acyltransfer in rat and human plasma
Biochem Soc Trans (1987) 15 (3): 487–488.
The phospholipase A1 activity in mouse preheparin plasma indicates high levels of unbound hepatic lipase in this species
Biochem Soc Trans (1987) 15 (3): 488–489.
Plasma lipids in retinitis pigmentosa
CAROLYN A. CONVERSE; TRACEY McLACHLAN; ALISON C. BOW; EMILIO ALVAREZ; LUBNA HUQ; CHRISTOPHER J. PACKARD; JAMES SHEPHERD
Biochem Soc Trans (1987) 15 (3): 490–491.
Isolation of a phosphopeptide from bovine hormone-sensitive lipase
Biochem Soc Trans (1987) 15 (3): 491–492.
PhosphatithIcholine synthesis and secretion by isolated rat hepatocytes
Biochem Soc Trans (1987) 15 (3): 493–494.
Purification and characterization of cellular retinoid-binding proteins from human spleen and placenta
Biochem Soc Trans (1987) 15 (3): 495–496.
Effect of supplementation with dihomo-γ-linolenic acid in a subject with cystic fibrosis
Biochem Soc Trans (1987) 15 (3): 497.
Effects of prolonged ethanol consumption on cholinergic function in the basal forebrain and memory
Biochem Soc Trans (1987) 15 (3): 499–500.
Comparison of 125I-α-bugarotoxin and (–)-[3H]nicotine binding in insect ganglia
Biochem Soc Trans (1987) 15 (3): 500–501.
N-Methyl-d-aspartate increases rat brain synaptosomal free calcium
Biochem Soc Trans (1987) 15 (3): 501–502.
Effect of phospholipase C and a rat muscle factor on the binding of α-bungarotoxin
Biochem Soc Trans (1987) 15 (3): 503.
t-Butylbicyclophosphoro[35S]thionate binding to ganglionic membranes of the locust (Schistocerca gregaria)
Biochem Soc Trans (1987) 15 (3): 503–504.
Region-specific defects in glutamate and γ-aminobutyric acid innervation in Alzheimer's disease
Biochem Soc Trans (1987) 15 (3): 505–506.
The αC2 distortion: a recurring structural motif in proteins
Biochem Soc Trans (1987) 15 (3): 506–507.
Trisomy-16 foetal mouse fibroblasts accumulate higher than normal levelsof cyclic AMP in response to β-adrenergic stimulation
Biochem Soc Trans (1987) 15 (3): 508–509.
Lack of effect of modulators of renal phosphate handling on basolateral membrane transport in proximal-tubule cells
Biochem Soc Trans (1987) 15 (3): 509–510.
Purification properties and functional groups of bovine liver xanthine oxidase
Biochem Soc Trans (1987) 15 (3): 511–512.
The molecular mass and trimeric nature of chloramphenicol transacetylase
Biochem Soc Trans (1987) 15 (3): 513.
Putative irreversible inhibitors of trypsin-like enzymes: analogues of basic amino acids bearing a carbodi-imide moiety
Biochem Soc Trans (1987) 15 (3): 513–514.
Platelet aggregation induced by a hepatocellular carcinoma cell line
Biochem Soc Trans (1987) 15 (3): 516–517.
The significance of cholesterol and its autoxidation in relation to thromboplastin activity
Biochem Soc Trans (1987) 15 (3): 517–518.
Characterization of α-adrenergic receptors in rat islets of Langerhans
Biochem Soc Trans (1987) 15 (3): 518–519.
The influence of proteases on the colony-forming efficiency of human keratinocytes in culture
Biochem Soc Trans (1987) 15 (3): 519–520.
An extracellular protease from the alga Chlorella sphaerkii
Biochem Soc Trans (1987) 15 (3): 520–521.
α-Glucosidase inhibitory activities from freshwater green algae
Biochem Soc Trans (1987) 15 (3): 521.
Bicarbonate dehydration kinetics and sulphonamide inhibition of carbonic anhydrase isoenzymes
Biochem Soc Trans (1987) 15 (3): 523–524.
Porphyrin synthesis during pregnancy and lactation in the golden hamster
FIONA M. KELLY; KENNETH J. MURRAY; J. ANGELE MAHARAJ; S. LOUISE STEWART; ANTHONY P. PAYNE; ROSEMARY C. SPIKE; GEORGE G. THOMPSON; MICHAEL R. MOORE
Biochem Soc Trans (1987) 15 (3): 527–528.
Cytochemical demonstration of 5′-nucleotidase in rat brain synaptosomes
Biochem Soc Trans (1987) 15 (3): 528–529.
Inhibitors of enzyme efflux from damaged skeletal muscle do not influence ultrastructural damage
Biochem Soc Trans (1987) 15 (3): 530.
The low-conductance delayed rectifier potassium channel involved in the action potential: a new hypothesis
Biochem Soc Trans (1987) 15 (3): 530–531.
Inhibition of proteoglycan synthesis in cartilage by high hydrostatic pressure
Biochem Soc Trans (1987) 15 (3): 531–532.
Anomalous effects of membrane transport inhibitors at low temperatures
Biochem Soc Trans (1987) 15 (3): 532–533.
Effects of temperature on (Na+ + K+) co-transport in erythrocytes from hibernators and non-hibernators
Biochem Soc Trans (1987) 15 (3): 533–534.
Localization and characterization of glutaminase activity in the murine macrophage
Biochem Soc Trans (1987) 15 (3): 536.
Purification of the major ricin 120-binding proteins of rat spleen by preparative gel electrophoresis
Biochem Soc Trans (1987) 15 (3): 537.
A fast protein liquid chromatography procedure for the assessment of subunit heterogeneity of plant 11S storage globulins
Biochem Soc Trans (1987) 15 (3): 538–539.
Detection of the sickle cell mutation using synthetic oligonucleotide probes
Biochem Soc Trans (1987) 15 (3): 543–544.
Phorbol myristoyl acetate- and endotoxin-stimulated generation of intracellular superoxide in human monocytes during endotoxaemia
Biochem Soc Trans (1987) 15 (3): 544–545.
Selective binding of endotoxin by human monocytes demonstrated using flo cytometry: requirement of serum
Biochem Soc Trans (1987) 15 (3): 545–546.
Use of DNA probes to detect mycobacterial DNA in tuberculosis tissue
Biochem Soc Trans (1987) 15 (3): 548–549.
The use of cloned mycobacterial DNA probes for the detection of mycobacteria in Crohn's disease tissue
Biochem Soc Trans (1987) 15 (3): 549–550.
Extracellular products of mutant strains of Vibrio cholerae: physiological response
Biochem Soc Trans (1987) 15 (3): 550–551.
Gaucher's disease: increase of di- and tri-peptidyl carboxypeptidase in plasma
MARC VAN SANDE; SIMON SCHARPE; FRANCOIS VAN HOOF; THIERRY DE BARSY; JIN-ICHI INOKUCHI; DIRK HENDRIKS
Biochem Soc Trans (1987) 15 (3): 552–553.
Kininase I and kininase II serum activity in Plasmodium falciparum infection
Biochem Soc Trans (1987) 15 (3): 553–554.
Structure of Molluscum contagiosum virus DNA and mapping of an epidermal growth factor-like coding sequence
Biochem Soc Trans (1987) 15 (3): 554–555.
Reduced concentrations of purine nucleotides in hypoxanthine phosphoribosyltransferase-deficient human lymphoblasts
Biochem Soc Trans (1987) 15 (3): 555–556.
Coxsackie B virus in biopsies from patients with myocarditis, dilated cardiomyopathy or skeletal muscle diseases
Biochem Soc Trans (1987) 15 (3): 556–557.
Stability of brain RNA post mortem: effect of Alzheimer's disease
Biochem Soc Trans (1987) 15 (3): 558–559.
Quantitative and qualitative characterization of serum and urine glycosaminoglycans in hyperthyroidism
Biochem Soc Trans (1987) 15 (3): 559–560.
Cloned mRNA sequences from the human colon: their potential use in the early diagnosis of neoplasia
Biochem Soc Trans (1987) 15 (3): 560.
Effect of mefloquine on the turnover of rat liver microsomal proteins
Biochem Soc Trans (1987) 15 (3): 561–562.
Spectral interactions of isonitrile odorants with hepatic and olfactory cytochrome P-450
Biochem Soc Trans (1987) 15 (3): 562–563.
Prostacyclin production by cultured human endothelial cells and tissue homogenates in response to fish liver extracts
Biochem Soc Trans (1987) 15 (3): 563–564.
Computer Software Review
Book Review
Ion-Exchange Sorption and Preparative Chromatography of Biologically Active Molecules
Biochem Soc Trans (1987) 15 (3): 569–570.