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April 1986
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ISSN 0300-5127
EISSN 1470-8752
In this Issue
Twenty-Second Colworth Medal Lecture
614th Meeting
Proteins Acting on DNA
Mechanism of activation of transcription by the complex formed between cyclic AMP and its receptor in Escherichia coli
Biochem Soc Trans (1986) 14 (2): 196–199.
Oligodeoxynucleotides covalently linked to intercalating agents: a new family of gene regulatory substances
C. HÉLÉNE; T. MONTENAY-GARESTIER; T. SAISON-BEHMOARAS; J. J. TOULMÉ; M. BOIDOT-FORGET; C. CAZENAVE; U. ASSELINE; G. LANCELOT; J. C. MAURIZOT; F. TOULMÉ; N. T. THUONG
Biochem Soc Trans (1986) 14 (2): 201–202.
Structural and catalytic properties of specific complexes between Tn3 resolvase and the recombination site res
Biochem Soc Trans (1986) 14 (2): 214–216.
Repetitive Zn2+-binding domains in the protein transcription factor IIIA from Xenopus oocytes
Biochem Soc Trans (1986) 14 (2): 221.
A triple complex between transcription factor IIIA, a Xenopus gene for 5S RNA and the histone octamer
Biochem Soc Trans (1986) 14 (2): 221–222.
Brown Adipose Tissue
Sympathetic and hormonal regulation of brown adipose tissue thermogenesis
Biochem Soc Trans (1986) 14 (2): 230–233.
Molecular Mechanisms of Membrane Fusion
Cell fusion and measurement of membrane properties using electric fields and other forces
Biochem Soc Trans (1986) 14 (2): 246–249.
Structural changes in influenza virus haemagglutinin at the pH of membrane fusion
J. J. SKEHEL; R. S. DANIELS; A. J. HAY; R. RUIGROK; S. A. WHARTON; N. G. WRIGLEY; W. WEISS; D. C. WILLEY
Biochem Soc Trans (1986) 14 (2): 252–253.
COMMUNICATION
Cytosine: cytosine formed in duplex DNA by the ligation of NciI- or CauII-cleaved DNA
Biochem Soc Trans (1986) 14 (2): 259.
Restriction-modification genes from bacterial genera which produce PstI isoschizomers
Biochem Soc Trans (1986) 14 (2): 261–262.
Cloning and overexpression of the Escherichia coli aroC gene encoding the enzyme chorismate synthase
Biochem Soc Trans (1986) 14 (2): 262–263.
Evidence for a mixed operon encoding enzymes from two different biosynthetic pathways
Biochem Soc Trans (1986) 14 (2): 263–264.
Evidence for the repair of the promutagenic lesion O6-methylguanine from mitochondrial DNA
Biochem Soc Trans (1986) 14 (2): 266–267.
Superhelicity and expression in vitro of the Escherichia coli lactose promoters: unwinding experiments and abortive initiation assays
Biochem Soc Trans (1986) 14 (2): 272–273.
Enhancer-dependent expression and processing of transcripts from a cloned trout protamine gene transferred into Hela cells
Biochem Soc Trans (1986) 14 (2): 273–274.
The spatial relationship between the ‘TATA-box’ and the site of initiation of transcription
Biochem Soc Trans (1986) 14 (2): 274–275.
Use of cloned cDNA sequences to measure changes in the level of brown fat uncoupling protein mRNA
Biochem Soc Trans (1986) 14 (2): 277.
Fatty acids of brown adipose tissue from obese and lean mice: effect of transplantation
Biochem Soc Trans (1986) 14 (2): 279.
The role of ketone bodies in the conversion of fatty acids to cholesterol in liver
Biochem Soc Trans (1986) 14 (2): 280–281.
Increased response to noradrenaline of isolated brown adipocytes from guinea pigs during cold-adaptation
Biochem Soc Trans (1986) 14 (2): 282–283.
Decrease in mitochondrial GDP binding without parallel changes in uncoupling protein in brown adipose tissue of the guinea pig
Biochem Soc Trans (1986) 14 (2): 283–284.
Rates of lipogenesis in isolated brown adipocytes from newborn rats
Biochem Soc Trans (1986) 14 (2): 284.
Fatty acid composition of phospholipids from interscapular brown adipose tissue of obese and lean Zucker rats
Biochem Soc Trans (1986) 14 (2): 287–288.
Electron microscope immunocytochemical localization of uncoupling protein in rat brown adipose tissue
Biochem Soc Trans (1986) 14 (2): 289–290.
The effect of palmitoyl-CoA on GDP binding to brown adipose tissue mitochondria from lean and obese Zucker rats
Biochem Soc Trans (1986) 14 (2): 290–291.
The rapid isolation, using a vertical rotor, of rat liver endocytic vesicles involved in transfer of polymeric IgA from blood to bile
Biochem Soc Trans (1986) 14 (2): 296–297.
Electrically induced cell fusion in the production of monoclonal antibodies
Biochem Soc Trans (1986) 14 (2): 297–298.
Transfer of the reconstituted epidermal growth factor receptor to receptor-negative cells by liposome fusion
Biochem Soc Trans (1986) 14 (2): 298–299.
The translocation of phospholipids and wax esters from the cytoplasmic to outer membrane of the cell envelope in Micrococcus cryophilus
Biochem Soc Trans (1986) 14 (2): 302–303.
Monoclonal antibody studies of creatine kinase: cross-reaction between chicken and human enzymes
Biochem Soc Trans (1986) 14 (2): 304.
3-Hydroxy-7,8-dihydro-7,8-dihydroxybenzo[a]pyrene: a biliary metabolite of 3-hydroxybenzo[a]pyrene in the rat
Biochem Soc Trans (1986) 14 (2): 305.
Inhibition of placental γ-glutamyltransferase results in a decreased placental transfer of alanine
Biochem Soc Trans (1986) 14 (2): 306–307.
The handling of proinsulin and [Nα-GlyA1,Nε-LysB29-dodecanediol]insulin by the isolated prefused rat kidney
Biochem Soc Trans (1986) 14 (2): 307–308.
Fuel homoeostasis after partial hepatectomy in the rat: effects of inhibition of fat oxidation by 2-tetradecylglycidate
Biochem Soc Trans (1986) 14 (2): 308–309.
The effects of two inhalational anaesthetic agents on carbohydrate metabolism in the isolated, perfused, rabbit lung
Biochem Soc Trans (1986) 14 (2): 309–310.
Insulin antagonizes the glucagon-mediated stimulation of phenylalanine hydroxylase activity in isolated liver cells
Biochem Soc Trans (1986) 14 (2): 310–311.
Are the γ-glutamyl-amino acids signals for the amino acid uptake by lactating mammary gland?
Biochem Soc Trans (1986) 14 (2): 311–312.
The action of phenylarsine oxide on insulin stimulation of glucose transport in rat adipocytes
Biochem Soc Trans (1986) 14 (2): 313–314.
Use of permeabilized mitochondria in the study of insulin-induced pyruvate dehydrogenase activation
Biochem Soc Trans (1986) 14 (2): 314–315.
Involvement of protein kinase C in intracellular mechanisms regulating gastric acid secretion
Biochem Soc Trans (1986) 14 (2): 315–316.
Immunoaffinity purification of insulin receptor by use of monclonal antibodies
Biochem Soc Trans (1986) 14 (2): 316–317.
Insulin-inhibitory and insulin-like effects of monoclonal antibodies for the human insulin receptor
Biochem Soc Trans (1986) 14 (2): 317–318.
Molecular cloning and bacterial expression of a peptide with immunological similarity to the insulin receptor
Biochem Soc Trans (1986) 14 (2): 318–319.
The kinetics of the insulin, catecholamine and adenosine interaction in the regulation of adipocyte glucose transport
Biochem Soc Trans (1986) 14 (2): 319–320.
Dephosphorylation of branched-chain 2-oxoacid dehydrogenase complex by a mitochondrial protein phosphatase
Biochem Soc Trans (1986) 14 (2): 325.
The effect of adenosine deaminase on insulin sensitivity in the extensor digitorum longus muscle of the rat
Biochem Soc Trans (1986) 14 (2): 328–329.
Synergistic effects of growth hormone and prolactin on lactation, using a specific antiserum to rat growth hormone and bromocryptine
Biochem Soc Trans (1986) 14 (2): 330–331.
Applications of cellulose acetate and gel electrophoresis in the study of dermatan sulphate proteoglycans
Biochem Soc Trans (1986) 14 (2): 331–332.
Characterization of purified rat thyroglobulin and thyroglobulin secreted by FRTL-5 cells
Biochem Soc Trans (1986) 14 (2): 337–338.
Assessment of a multi-wire camera for quantitative autoradiography
Biochem Soc Trans (1986) 14 (2): 338.
Polypeptide synthesis by human polymorphonuclear leucocytes in response to dexamethasone
Biochem Soc Trans (1986) 14 (2): 342–343.
Effects of tolbutamide, aminoglutethimide, SU 10603 and SU 9055 on steroid metabolism in rat adrenal
Biochem Soc Trans (1986) 14 (2): 344–345.
Dantrolene sodium and verapamil increase pancuronium-induced neuromuscular blockade in the chick skeletal muscle
Biochem Soc Trans (1986) 14 (2): 347.
Phosphorylation in vivo of the larger subunit of 2′,3′-cyclic nucleotide-3′-phosphohydrolase in rabbit central nervous system myelin
Biochem Soc Trans (1986) 14 (2): 351–352.
A DNA-sequencing approach to the structure of a key brain membrane endopeptidase
IAN S. FULCHER; JANE R. GRIFFIN; GILLIAN T. BOTTOMLEY; STEPHEN J. HIGGINS; B. DAVID HAMES; ANTHONY J. TURNER; A. JOHN KENNY
Biochem Soc Trans (1986) 14 (2): 352–353.
Polyphosphoinositide labelling in Chinese hamster ovary (CHO-K1) cells: stimulation by serum and reduction by calcium ionophore A23187
Biochem Soc Trans (1986) 14 (2): 357–358.
Developmental changes in the polypeptide profiles of different cochlear regions in rodents
Biochem Soc Trans (1986) 14 (2): 358–359.
Synaptic nerve-endings (synaptosomes) with cholinergic properties from a simple nervous system
Biochem Soc Trans (1986) 14 (2): 359–360.
MAPI(x), a rat brain-specific microtubule-associated protein, is present in developing but not mature axons
Biochem Soc Trans (1986) 14 (2): 362.
Role of intracellular Ca2+ stores in neurotransmitter release from isolated neuronal growth cones
Biochem Soc Trans (1986) 14 (2): 363.
myo-Inositol metabolism and (Na+ + K+)-ATPase activity in relation to peripheral nerve function in rats with streptozotocin-induced diabetes
Biochem Soc Trans (1986) 14 (2): 364–365.
An immunologically active fragment of Tamm-Horsfall glycoprotein, derived by trypsinization
Biochem Soc Trans (1986) 14 (2): 367.
Iron-mediated free-radical effects on erythrocytes: the role of desferrioxamine
Biochem Soc Trans (1986) 14 (2): 368–369.
615th Meeting
Queen's University, Distinguished Scholar's Lecture
Analogues of folate antagonists as affinity and fluorescent probes of dihydrofolate reductase structure and function
Biochem Soc Trans (1986) 14 (2): 371–373.
Action Cancer Guest Lecture
Prodrugs
Lipoidal anti-inflammatory prodrugs as local targeting agents
ANDREW J. BILSKI; J. RAY EVANS; MICHAEL P. HARRISON; GERAINT JONES; TIMOTHY R. MARTEN; GEWN T. MILBURN; DAVID S. THOMSON; DAVID F. WHITE
Biochem Soc Trans (1986) 14 (2): 388–391.
Suicide Substrates
A new perspective on pyridoxal chemistry and its relevance to enzyme inhibition
Biochem Soc Trans (1986) 14 (2): 404–408.
Anti-convulsant effects of manipulation of brain 4-aminobutyrate concentrations by selective enzyme inhibition
Biochem Soc Trans (1986) 14 (2): 408–410.
The rational design of suicide substrates of amine oxidases
MICHAEL G. PALFREYMAN; IAN A. MCDONALD; PHILIPPE BEY; CHARLES DANZIN; MONIQUE ZREIKA; GEOFFREY A. LYLES; JOHN R. FOZARD
Biochem Soc Trans (1986) 14 (2): 410–413.
What to Leave Out: Curriculum Development in Biochemistry
COMMUNICATION
Analysis of Candida albicans antigens by sodium dodecyl sulphate/polyacrylamide-gel electrophoresis and immunoblotting
Biochem Soc Trans (1986) 14 (2): 435–436.
Electrophoretic analysis of changes in beef myofibrillar proteins during the early post-mortem period
Biochem Soc Trans (1986) 14 (2): 436–438.
Properties of the complexes formed between 8-halogenated flavins and apo-electron-transferring flavoprotein from Megasphaera elsdenii
Biochem Soc Trans (1986) 14 (2): 440–441.
Changes in the relative proportions of the microheterogenous forms of human plasma orosomucoid (α1-acid glycoprotein) after surgical trauma
Biochem Soc Trans (1986) 14 (2): 441–442.
The plasma membrane of murine spermatozoa: surface-labelling using isethionyl-[1-14C]acetimidate
Biochem Soc Trans (1986) 14 (2): 442–443.
A study in vivo of mammary differentiation and involution during a normal lactation cycle in the mouse
Biochem Soc Trans (1986) 14 (2): 443–444.
A volatile solvent for high-performance gel-permeation chromatography of polypeptides
Biochem Soc Trans (1986) 14 (2): 445–446.
The effects of Mg2+ or EDTA on the subcellular distribution of unoccupied oestrogen receptor in ZR-75-1 and MCF-7 cells
Biochem Soc Trans (1986) 14 (2): 447.
The influence of vincristine on the oestrogen-binding capacity of two human breast cancer cell lines in vitro
Biochem Soc Trans (1986) 14 (2): 449–450.
Identification of cell types in human muscle cultures using two-dimensional polyacrylamide-gel electrophoresis and immunofluorescence with monoclonal antibodies
Biochem Soc Trans (1986) 14 (2): 451–452.
The induction of an arginine-metabolizing enzyme in Methanobrevibacter smithii PS
Biochem Soc Trans (1986) 14 (2): 453–454.
Cd2+ may cause changes in transmitter function by inhibiting monoamine oxidase activity
Biochem Soc Trans (1986) 14 (2): 454–455.
Cauliflower curds of different cultivars show distinct isoenzyme differences in acid phosphatases and aspartate aminotransferase
Biochem Soc Trans (1986) 14 (2): 455–456.
A kinetic study of the behaviour of plasminogen activators towards synthetic substrates
Biochem Soc Trans (1986) 14 (2): 457–458.
Results of a questionnaire on the acceptance of a general biochemistry course by first-year life-science students
Biochem Soc Trans (1986) 14 (2): 462.
A program for the analysis of students' enzyme kinetics results with diagnosis of experimental inadequacies
Biochem Soc Trans (1986) 14 (2): 466.
The production and characterization of monoclonal antibodies to Landschutz ascites tumour cells
Biochem Soc Trans (1986) 14 (2): 471–472.
Isolation of chromosome 21-specific sequences responsible for the phenotypic expression of Down's syndrome
Biochem Soc Trans (1986) 14 (2): 476–477.
A comparison of Ca2+ -induced Ca2+ -release systems in rat and human sarcoplasmic reticulum
Biochem Soc Trans (1986) 14 (2): 481–482.
Reactivity of anti-HL-60 cell monoclonal antibody with normal and leukaemic bone marrow samples
Biochem Soc Trans (1986) 14 (2): 482–483.
Effect of γ-irradiation on the adhesion of baby hamster kidney cells (BHK 21)
Biochem Soc Trans (1986) 14 (2): 485–486.
The response of cultured Trypanosmona brucei to DNA-damaging agents
Biochem Soc Trans (1986) 14 (2): 486–487.
DNA Topoisomerase Inhibitors as Anti-Microbial Agents
DNA breakage by Escherichia coli DNA gyrase in vitro and in vivo
Biochem Soc Trans (1986) 14 (2): 493–496.
The action of quinolone carboxylic acids on Chlamydia trachomatis in vitro
Biochem Soc Trans (1986) 14 (2): 503–504.
Book Review
A History of Biochemistry: Selected Topics in the History of Biochemistry. Personal Recollections I (Comprehensive Biochemistry, Vol. 35)
Biochem Soc Trans (1986) 14 (2): 509–510.
NMR of Newly Accessible Nuclei (Volume 1, Chemical and Biochemical Applications; Volume 2, Chemically and Biochemically Important Elements)
Biochem Soc Trans (1986) 14 (2): 510.