Volume 44 (1), pp 13-17

The wrong version of Figure 1 was published in this article; the correct version is presented here. In the original Figure 1 the phosphoramidate was improperly represented with a phosphate linked to the oxygen group. The correct bond is P-N.

Model of two independent PTMs, serine-pyrophosphorylation and lysine-polyphosphorylation

Figure 1
Model of two independent PTMs, serine-pyrophosphorylation and lysine-polyphosphorylation

Protein pyrophosphorylation is the transfer of the b-phosphate group of the pyrophosphate moiety of IP7 on to a pre-phosphorylated serine residue (left) [16,17]. Conversely, protein polyphosphorylation is the covalent attachment of a chain of inorganic polyP on to a lysine residue dependent on the hydrolysis of an internal phosphate ester linkage (right) [1].

Figure 1
Model of two independent PTMs, serine-pyrophosphorylation and lysine-polyphosphorylation

Protein pyrophosphorylation is the transfer of the b-phosphate group of the pyrophosphate moiety of IP7 on to a pre-phosphorylated serine residue (left) [16,17]. Conversely, protein polyphosphorylation is the covalent attachment of a chain of inorganic polyP on to a lysine residue dependent on the hydrolysis of an internal phosphate ester linkage (right) [1].

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