The Centre for Synthetic and Systems Biology ('SynthSys') was originally established in 2007 as the Centre for Integrative Systems Biology, funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Engineering and Physical Sciences Research Council (EPSRC). Today, SynthSys embraces an extensive multidisciplinary community of more than 200 researchers from across the University with a common interest in synthetic and systems biology. Our research is broad and deep, addressing a diversity of scientific questions, with wide ranging impact. We bring together the power of synthetic biology and systems approaches to focus on three core thematic areas: industrial biotechnology, agriculture and the environment, and medicine and healthcare. In October 2015, we opened a newly refurbished building as a physical hub for our new U.K. Centre for Mammalian Synthetic Biology funded by the BBSRC/EPSRC/MRC as part of the U.K. Research Councils' Synthetic Biology for Growth programme.
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June 2016
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Cover Image
Cover Image
Shining a spotlight on outer membrane protein folding. Outer membrane proteins (OMPs) [such as OmpA (green, top left)] have to navigate their way from the ribosome (bottom of image) via trigger factor (red) and SecB (turquoise), through the SecYEG translocon (red/yellow) in the inner membrane (IM). They are then chaperoned across the periplasm until they can insert and fold into their ultimate destination, the outer membrane. For further details see pp. 802–809. The figure was produced by Jim Horne. - PDF Icon PDF LinkTable of Contents
Review Article|
June 09 2016
Exploring Synthetic and Systems Biology at the University of Edinburgh
Liz Fletcher;
Liz Fletcher
1
1U.K. Centre for Mammalian Synthetic Biology, University of Edinburgh, Edinburgh EH8 9YL, U.K.
1To whom correspondence should be addressed (email liz.fletcher@ed.ac.uk).
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Susan Rosser;
Susan Rosser
1U.K. Centre for Mammalian Synthetic Biology, University of Edinburgh, Edinburgh EH8 9YL, U.K.
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Alistair Elfick
Alistair Elfick
2Centre for Synthetic and Systems Biology, University of Edinburgh, Edinburgh EH9 3BF, U.K.
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Publisher: Portland Press Ltd
Received:
January 15 2016
Online ISSN: 1470-8752
Print ISSN: 0300-5127
© 2016 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society
2016
Biochem Soc Trans (2016) 44 (3): 692–695.
Article history
Received:
January 15 2016
Citation
Liz Fletcher, Susan Rosser, Alistair Elfick; Exploring Synthetic and Systems Biology at the University of Edinburgh. Biochem Soc Trans 15 June 2016; 44 (3): 692–695. doi: https://doi.org/10.1042/BST20160006
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