The present mini-review covers the local and global geometry of framed curves and the computation of twist and writhe in knotted DNA circles. Classical inequalities relating the total amount of bending of a closed space curve and associated knot parameters are also explained.

Keywords:
continuum model, DNA, framed curve, knotted DNA, space curve, twist, writhe
© The Authors Journal compilation © 2013 Biochemical Society
2013
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