TSEs (transmissible spongiform encephalopathies) are neurodegenerative diseases of various mammalian species, the best known of which include BSE (bovine spongiform encephalopathies) in cattle, CJD (Creutzfeldt–Jakob disease) in humans, scrapie in sheep and CWD (chronic wasting disease) in deer. This review examines the emergence of various TSE strains and their transmission, and discusses disease surveillance and control.

Keywords:
bovine spongiform encephalopathy (BSE), chronic wasting disease (CWD), Creutzfeldt–Jakob disease (CJD), prion protein (PrP), scrapie, transmissible spongiform encephalopathy (TSE)
© 2006 The Biochemical Society
2006
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