Primary cilia are sensory organelles that play a role as signalling hubs. Disruption of primary cilia structure and function is increasingly recognised in a range of cancers, with a growing body of evidence suggesting that ciliary disruption contributes to tumourigenesis. This review considers the role of primary cilia in the pathogenesis of endocrine-related cancers.
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Review Article| October 19 2016
Primary cilia: a link between hormone signalling and endocrine-related cancers?
Samuel M. O'Toole;
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Samuel M. O'Toole, J. Paul Chapple; Primary cilia: a link between hormone signalling and endocrine-related cancers?. Biochem Soc Trans 15 October 2016; 44 (5): 1227–1234. doi: https://doi.org/10.1042/BST20160149
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