Both helminth infections and contact with allergens result in development of a Th2 type of immune response in the affected individual. In this context, the hygiene hypothesis suggests that reduced prevalence of parasitic infections and successful vaccination strategies are causative for an increase of allergies in industrialized countries. It is therefore of interest to study glycans and their role as immunogenic structures in both parasitic infections and allergies. In the present paper we review information on the different types of glycan structure present in proteins from plant and animal food, insect venom and helminth parasites, and their role as diagnostic markers. In addition, the application of these glycan structures as immunomodulators in novel immunotherapeutic strategies is discussed.
Skip Nav Destination
Article navigation
February 2011
-
Cover Image
Cover Image
- PDF Icon PDF LinkFront Matter
- PDF Icon PDF LinkTable of Contents
Conference Article|
January 19 2011
Glycomarkers in parasitic infections and allergy
Karin Hoffmann-Sommergruber;
Karin Hoffmann-Sommergruber
*Institut für Pathophysiologie und Allergieforschung, Medizinische Universität Wien, 1090 Wien, Austria
Search for other works by this author on:
Katharina Paschinger;
Katharina Paschinger
†Department für Chemie, Universität für Bodenkultur Wien, 1190 Wien, Austria
Search for other works by this author on:
Iain B.H. Wilson
Iain B.H. Wilson
1
†Department für Chemie, Universität für Bodenkultur Wien, 1190 Wien, Austria
1To whom correspondence should be addressed (email iain.wilson@boku.ac.at).
Search for other works by this author on:
Publisher: Portland Press Ltd
Received:
October 19 2010
Online ISSN: 1470-8752
Print ISSN: 0300-5127
© The Authors Journal compilation © 2011 Biochemical Society
2011
Biochem Soc Trans (2011) 39 (1): 360–364.
Article history
Received:
October 19 2010
Citation
Karin Hoffmann-Sommergruber, Katharina Paschinger, Iain B.H. Wilson; Glycomarkers in parasitic infections and allergy. Biochem Soc Trans 1 February 2011; 39 (1): 360–364. doi: https://doi.org/10.1042/BST0390360
Download citation file:
Sign in
Don't already have an account? Register
Sign in to your personal account
You could not be signed in. Please check your email address / username and password and try again.
Captcha Validation Error. Please try again.