NATs (natural antisense transcripts) are important regulators of eukaryotic gene expression. Interference between the expression of protein-coding sense transcripts and the corresponding NAT is well documented. In the present review, we focus on an additional, higher-order role of NATs that is currently emerging. The recent discovery of endogenous siRNAs (short interfering RNAs), as well as NAT-induced transcriptional gene silencing, are key to the proposed novel function of NATs.
Skip Nav Destination
Conference Article| July 26 2010
What are natural antisense transcripts good for?
Andreas Werner 1
*RNA Biology Group, Institute for Cell and Molecular Biosciences, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, U.K.
1To whom correspondence should be addressed (email firstname.lastname@example.org).
Search for other works by this author on:
- Views Icon Views
- Share Icon Share
Andreas Werner, Daniel Swan; What are natural antisense transcripts good for?. Biochem Soc Trans 1 August 2010; 38 (4): 1144–1149. doi: https://doi.org/10.1042/BST0381144
Download citation file:
Don't already have an account? Register
Get Access To This Article
Buy This Article