Spliced leader trans-splicing occurs in many primitive eukaryotes including nematodes. Most of our knowledge of trans-splicing in nematodes stems from the model organism Caenorhabditis elegans and relatives, and from work with Ascaris. Our investigation of spliced leader trans-splicing in distantly related Dorylaimia nematodes indicates that spliced-leader trans-splicing arose before the nematode phylum and suggests that the spliced leader RNA gene complements in extant nematodes have evolved from a common ancestor with a diverse set of spliced leader RNA genes.
The evolution of spliced leader trans-splicing in nematodes
Jonathan Pettitt, Neale Harrison, Ian Stansfield, Bernadette Connolly, Berndt Müller; The evolution of spliced leader trans-splicing in nematodes. Biochem Soc Trans 1 August 2010; 38 (4): 1125–1130. doi: https://doi.org/10.1042/BST0381125
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