Transcription factors of the ETS family are important regulators of endothelial gene expression. Here, we review the evidence that ETS factors regulate angiogenesis and briefly discuss the target genes and pathways involved. Finally, we discuss novel evidence that shows how these transcription factors act in a combinatorial fashion with others, through composite sites that may be crucial in determining endothelial specificity in gene transcription.
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Conference Article| November 19 2009
Regulation of angiogenesis by ETS transcription factors
Anna M. Randi;
Anna M. Randi 1
1National Heart and Lung Institute (NHLI) Cardiovascular Sciences Unit, Hammersmith Hospital, Du Cane Road, Imperial College London, London W12 0NN, U.K.
1To whom correspondence should be addressed (email email@example.com).
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Nicola H. Dryden;
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Anna M. Randi, Andrea Sperone, Nicola H. Dryden, Graeme M. Birdsey; Regulation of angiogenesis by ETS transcription factors. Biochem Soc Trans 1 December 2009; 37 (6): 1248–1253. doi: https://doi.org/10.1042/BST0371248
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