The metabolism of tryptophan by the kynurenine pathway leads to the production of several neurotoxic compounds, some of which have been associated with neurological disorders. Recent investigation of some relevant compounds in this pathway has provided further evidence of their neurotoxicity.
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Conference Article| October 25 2007
Neurotoxicity of tryptophan metabolites
A.J. Smith 1
1Division of Neuroscience and Biomedical Systems, Institute of Biomedical and Life Sciences, West Medical Building, University of Glasgow, Glasgow G12 8QQ, U.K.
1To whom correspondence should be addressed (email firstname.lastname@example.org).
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Publisher: Portland Press Ltd
Received: July 06 2007
Online ISSN: 1470-8752
Print ISSN: 0300-5127
© The Authors Journal compilation © 2007 Biochemical Society
A.J. Smith, T.W. Stone, R.A. Smith; Neurotoxicity of tryptophan metabolites. Biochem Soc Trans 1 November 2007; 35 (5): 1287–1289. doi: https://doi.org/10.1042/BST0351287
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