Although it has been known for many years that dietary lipids influence the development of atherosclerosis, in the past this has been attributed to their effects on blood cholesterol levels. Recent work, however, has shown that CMRs (chylomicron remnants), the lipoproteins which carry dietary lipids in the blood, potentially have a direct role in initiating atherogenesis by influencing vascular function. The Diet and Cardiovascular Health: Chylomicron Remnants and Their Emerging Roles in Vascular Dysfunction in Atherosclerosis Meeting focused attention on studies which have shown that CMRs influence vascular function via interactions with cells of the artery wall, including endothelial cells and macrophages, and also highlighted the part played by CMRs in the development of premature atherosclerosis in conditions such as the metabolic syndrome, which are an increasing cause of heart disease in developed countries.
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Conference Article|
May 22 2007
Introduction to the Biochemical Society Focused Meeting on Diet and Cardiovascular Health: Chylomicron Remnants and Their Emerging Roles in Vascular Dysfunction in Atherosclerosis
K.M. Botham;
K.M. Botham
1
1Department of Veterinary Basic Sciences, The Royal Veterinary College, Royal College Street, London NW1 0TU, U.K.
1To whom correspondence should be addressed (email kbotham@rvc.ac.uk).
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C.P.D. Wheeler-Jones
C.P.D. Wheeler-Jones
1Department of Veterinary Basic Sciences, The Royal Veterinary College, Royal College Street, London NW1 0TU, U.K.
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Publisher: Portland Press Ltd
Received:
February 28 2007
Online ISSN: 1470-8752
Print ISSN: 0300-5127
© 2007 Biochemical Society
2007
Biochem Soc Trans (2007) 35 (3): 437–439.
Article history
Received:
February 28 2007
Citation
K.M. Botham, C.P.D. Wheeler-Jones; Introduction to the Biochemical Society Focused Meeting on Diet and Cardiovascular Health: Chylomicron Remnants and Their Emerging Roles in Vascular Dysfunction in Atherosclerosis. Biochem Soc Trans 1 June 2007; 35 (3): 437–439. doi: https://doi.org/10.1042/BST0350437
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