Meiosis creates haploid cells from diploid progenitors. Homologous chromosomes are moved, paired and segregated from each other in a specialized meiosis I division. A second division that lacks a preceding S-phase produces haploid cells. In prophase I, chromosomes attach with their telomeres to the nuclear envelope and undergo oscillating movements that become restricted to a limited nuclear sector during the widely conserved bouquet stage. Recent observations in budding yeast meiosis suggest that telomere clustering depends on actin, whereas exit from the bouquet stage requires meiotic cohesin. Telomere clustering may also be modulated by progression in recombination. These observations suggest that the unique meiotic nuclear topology and telomere dynamics are regulated at different levels.
Skip Nav Destination
Article navigation
August 2006
-
Cover Image
Cover Image
- PDF Icon PDF LinkFront Matter
- PDF Icon PDF LinkTable of Contents
Conference Article|
July 21 2006
Factors directing telomere dynamics in synaptic meiosis
H. Scherthan
H. Scherthan
1
1Max-Planck-Institute for Molecular Genetics, Berlin, Germany
Search for other works by this author on:
Publisher: Portland Press Ltd
Received:
March 23 2006
Online ISSN: 1470-8752
Print ISSN: 0300-5127
© 2006 The Biochemical Society
2006
Biochem Soc Trans (2006) 34 (4): 550–553.
Article history
Received:
March 23 2006
Citation
H. Scherthan; Factors directing telomere dynamics in synaptic meiosis. Biochem Soc Trans 1 August 2006; 34 (4): 550–553. doi: https://doi.org/10.1042/BST0340550
Download citation file:
Sign in
Don't already have an account? Register
Sign in to your personal account
You could not be signed in. Please check your email address / username and password and try again.
Captcha Validation Error. Please try again.