Three distinct genes encode α1-adrenoceptors. Although homodimers of each subtype have been reported, certain but not all combinations of heterodimers of the α1-adrenoceptors appear to form. Key studies in this field are reviewed and the approaches that have been applied to monitoring the selectivity and the basis of α1-adrenoceptor dimerization are discussed.
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Conference Article| October 26 2004
Dimerization of α1-adrenoceptors
G. Milligan 1
*Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland, U.K.
1To whom correspondence should be addressed (email firstname.lastname@example.org).
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G. Milligan, J. Pediani, M. Fidock, J.F. López-Giménez; Dimerization of α1-adrenoceptors. Biochem Soc Trans 1 November 2004; 32 (5): 847–850. doi: https://doi.org/10.1042/BST0320847
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