The oxidative modification of low-density lipoprotein (LDL) can be induced by various active species by different mechanisms. Vitamin E and other radical-scavenging antioxidants can inhibit the free radical-mediated oxidation of LDL, but they are not effective against LDL oxidation induced by non-radical mechanisms.

Keywords:
antioxidant, atherosclerosis, free radical, lipid peroxidation, low-density lipoprotein, vitamin E
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© 2004 Biochemical Society
2004
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