Members of the family of BPI (bactericidal/permeability-increasing protein)-like proteins are as yet incompletely characterized, particularly in cattle, where full-length sequence information is available for only three of the 13 family members known from other species. Structural bioinformatic analyses incorporating bovine homologues of several members of the BPI-like protein family, including two forms of bovine parotid secretory protein (PSP), showed that this family is also present in cattle. Expression analyses of several members of the BPI-like protein family in cattle, including PSP (Bsp30), von Ebner's minor salivary gland protein (VEMSGP) and lung-specific X protein (LUNX), showed a restricted pattern of expression, consistent with earlier hypotheses that these proteins function in the innate immune response to bacteria. The possible role of bovine PSP in susceptibility to pasture bloat in cattle is discussed.
Skip Nav Destination
Article navigation
August 2003
- PDF Icon PDF LinkFront Matter
Conference Article|
August 01 2003
Bovine parotid secretory protein: structure, expression and relatedness to other BPI (bactericidal/permeability-increasing protein)-like proteins
T.T. Wheeler;
T.T. Wheeler
1
*Dairy Biotechnology, AgResearch, Ruakura Research Centre, East St, Hamilton, New Zealand
1To whom correspondence should be addressed (e-mail tom.wheeler@agresearch.co.nz).
Search for other works by this author on:
K. Hood;
K. Hood
*Dairy Biotechnology, AgResearch, Ruakura Research Centre, East St, Hamilton, New Zealand
Search for other works by this author on:
K. Oden;
K. Oden
*Dairy Biotechnology, AgResearch, Ruakura Research Centre, East St, Hamilton, New Zealand
Search for other works by this author on:
J. McCracken;
J. McCracken
2
*Dairy Biotechnology, AgResearch, Ruakura Research Centre, East St, Hamilton, New Zealand
Search for other works by this author on:
C.A. Morris
C.A. Morris
†Animal Genomics, AgResearch, Ruakura Research Centre, East St, Hamilton, New Zealand
Search for other works by this author on:
Publisher: Portland Press Ltd
Online ISSN: 1470-8752
Print ISSN: 0300-5127
© 2003 Biochemical Society
2003
Biochem Soc Trans (2003) 31 (4): 781–784.
Citation
T.T. Wheeler, K. Hood, K. Oden, J. McCracken, C.A. Morris; Bovine parotid secretory protein: structure, expression and relatedness to other BPI (bactericidal/permeability-increasing protein)-like proteins. Biochem Soc Trans 1 August 2003; 31 (4): 781–784. doi: https://doi.org/10.1042/bst0310781
Download citation file:
Sign in
Don't already have an account? Register
Sign in to your personal account
You could not be signed in. Please check your email address / username and password and try again.
Captcha Validation Error. Please try again.