An immunosensing device, comprising a lipid membrane incorporating ion channels tethered to the surface of a gold electrode, has been reported [Cornell, Braach-Maksvytis, King, Osman, Raguse, Wieczorek and Pace (1997) Nature (London) 387, 580–583]. The present article describes key steps in the assembly of the device and provides further evidence for its proposed sensing mechanism.
Tethered-bilayer lipid membranes as a support for membrane-active peptides
B. A. Cornell, G. Krishna, P. D. Osman, R. D. Pace, L. Wieczorek; Tethered-bilayer lipid membranes as a support for membrane-active peptides. Biochem Soc Trans 1 August 2001; 29 (4): 613–617. doi: https://doi.org/10.1042/bst0290613
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