Investigation of electrostatic and hydrogen bonding interactions of caricain and caricain D158N with time-dependent inhibitors

HUSSAIN, SYEED; ALLEN, KIMBERLEY K.; CONNERTON, IAN F.; CUMMINGS, NICOLA J.; GUL, SHERAZ; KHAN, AKAVISH; TAYLOR, MARK A.J.; THOMAS, EMRYS W.; VERMA, CHANDRA; BROCKLEHURST, KEITH

doi:10.1042/bst027a037a

SYEED HUSSAIN;

SYEED HUSSAIN

¹Laboratory of Structural and Mechanistic Enzymology, Dept. of Biochemistry, Queen Mary and Westfield College, University of London, London El 4NS, UK

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KIMBERLEY K. ALLEN;

KIMBERLEY K. ALLEN

¹Laboratory of Structural and Mechanistic Enzymology, Dept. of Biochemistry, Queen Mary and Westfield College, University of London, London El 4NS, UK

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IAN F. CONNERTON;

IAN F. CONNERTON

²Protein Engineering Dept., Institute of Food Research, Reading Laboratory, Earley Gate, Whiteknights Road, Reading RG6 2EF, UK

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NICOLA J. CUMMINGS;

NICOLA J. CUMMINGS

²Protein Engineering Dept., Institute of Food Research, Reading Laboratory, Earley Gate, Whiteknights Road, Reading RG6 2EF, UK

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SHERAZ GUL;

SHERAZ GUL

¹Laboratory of Structural and Mechanistic Enzymology, Dept. of Biochemistry, Queen Mary and Westfield College, University of London, London El 4NS, UK

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AKAVISH KHAN;

AKAVISH KHAN

¹Laboratory of Structural and Mechanistic Enzymology, Dept. of Biochemistry, Queen Mary and Westfield College, University of London, London El 4NS, UK

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MARK A.J. TAYLOR;

MARK A.J. TAYLOR

²Protein Engineering Dept., Institute of Food Research, Reading Laboratory, Earley Gate, Whiteknights Road, Reading RG6 2EF, UK

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EMRYS W. THOMAS;

EMRYS W. THOMAS

³Dept. of Biological Sciences, University of Salford, Salford M5 4JW, UK

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CHANDRA VERMA;

CHANDRA VERMA

⁴Protein Structure Research Group, Dept. of Chemistry, University of York, Heslington, York Y01 5DD, UK

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KEITH BROCKLEHURST

¹Laboratory of Structural and Mechanistic Enzymology, Dept. of Biochemistry, Queen Mary and Westfield College, University of London, London El 4NS, UK

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Investigation of electrostatic and hydrogen bonding interactions of caricain and caricain D158N with time-dependent inhibitors

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