.... Leucine-rich repeat-containing 8A (LRRC8A), the core component of the volume-regulated anion channel, is closely associated with acquiring heterogeneity for tumor cells. However, the role of LRRC8A in the exosomes remains largely unknown. Here, we reported that LRRC8A was one of the compositions...

... bicarbonate transport Cl − /HCO 3 − anion exchanger (AE) Na + /HCO3 − co-transporter (NBC) pH regulation solute carrier (SLC) volume regulation Bicarbonate (HCO 3 − ) has a central position in mammalian physiology. Mitochondrial respiratory oxidation produces CO 2 as its oxidative waste...