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Keywords: tyrosine kinase inhibitors
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Biochem J (2023) 480 (2): 161–176.
Published: 31 January 2023
... pathways. With the development of specific BCR-ABL1 tyrosine kinase inhibitors (TKIs) CML became a much more tractable disease. Nevertheless, TKIs do not cure CML patients and a substantial number of them develop intolerance or become resistant to the treatment. Therefore, novel anti-cancer strategies must...