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Keywords: trypanosomes
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Biochem J (2022) 479 (17): 1743–1758.
Published: 06 September 2022
...Samuel M. Duncan; Michael A.J. Ferguson Eukaryotic protein glycosylation is mediated by glycosyl- and oligosaccharyl-transferases. Here, we describe how African trypanosomes exhibit both evolutionary conservation and significant divergence compared with other eukaryotes in how they synthesise...
Biochem J (2018) 475 (23): 3763–3778.
Published: 06 December 2018
... structure TbCentrin4 trypanosomes Figure 1. Sequence alignments and solution structure of TbCentrin4. ( A ) Multiple sequence alignments of TbCentrin4 with other centrins. Tb, T. brucei ; Hs, Homo sapiens . Identical residues are shaded in red box and conserved residues are colored in red...
Includes: Supplementary data
Biochem J (2018) 475 (16): 2593–2610.
Published: 29 August 2018
... drug metabolism isoprostane lipid mediators methylglyoxal trypanosomes Enzymatic activity was assessed by measuring the continuous oxidation of NADPH at 340 nm in the presence of varying concentrations of substrate using a Shimadzu UV-2401 or 1601 spectrophotometer. Measurements were...
Includes: Supplementary data
Biochem J (2017) 474 (22): 3817–3830.
Published: 09 November 2017
... at probable TSSs (transcription start sites) and may play an essential role in transcription initiation [ 21 ]. All these previous studies revealed that bromodomain-containing proteins are essential in the physiological regulation of trypanosome and are potential targets for therapy of trypanosomiasis...
Includes: Supplementary data
Biochem J (2017) 474 (14): 2315–2332.
Published: 27 June 2017
...-conicet.gov.ar ) 23 1 2017 1 6 2017 5 6 2017 6 6 2017 © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 Chagas disease complex IV heme A heme A synthase trypanosomes T. cruzi epimastigotes Dm28c, containing...
Includes: Supplementary data
Biochem J (1999) 338 (2): 545–551.
Published: 22 February 1999
...-lactosamine are 46 µ M and 4.5 mM respectively. From these results we would like to suggest that the galactosyltransferase functions in the processing of terminal N -acetyl-lactosamine structures of trypanosomal glycoproteins. 1 Present address: Department of Immunology, The Babraham Institute...