... Attribution License 4.0 (CC BY) . genomics hypoxia hypoxia inducible factors proteomics transcriptomics Molecular oxygen is best known for its connection to oxidative phosphorylation and ATP production. Changes to oxygen availability give rise to complex cellular and organismic responses...

... by the participation of University of Liverpool in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with JISC. flux host metabolomics optimisation proteomics transcriptomics Much of microbial biotechnology consists...

... neurotoxicity remain undefined. Understanding these processes will underpin therapeutic and control strategies for human and animal prion diseases, respectively. Prion diseases are difficult to study in their natural hosts and require the use of tractable animal models. Here we used RNA-Seq-based transcriptome...

... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . globotriaosylsphingosine lysosomal enzyme proteasome inhibitor protein misfolding transcriptomics Fabry disease (FD, OMIM 301500) is one of more than 40 lysosomal storage diseases (LSD) [ 1...

... 12 2019 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 apoptosis autophagy breast cancers DNA synthesis and repair lysosomes transcriptomics Breast cancer is a leading cause of death among women. Notably, five-year...

...Emre Amirak; Stephen J. Fuller; Peter H. Sugden; Angela Clerk ERK1/2 (extracellular-signal-regulated kinase 1/2) and their substrates RSKs (p90 ribosomal S6 kinases) phosphorylate different transcription factors, contributing differentially to transcriptomic profiles. In cardiomyocytes ERK1/2...