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Agnès Ribes, Antoine Oprescu, Julien Viaud, Karim Hnia, Gaëtan Chicanne, Jean-Marie Xuereb, Sonia Severin, Marie-Pierre Gratacap, Bernard Payrastre
Biochem J (2020) 477 (22): 4327–4342.
Published: 26 November 2020
... researchers to generate an impressive amount of data on the role of class I PI3Kα, β, δ and γ in platelet activation and in thrombosis. Furthermore, platelets do also express two class II PI3Ks (PI3KC2α and PI3KC2β), thought to generate PtdIns(3,4)P 2 and PtdIns3P, and the sole class III PI3K (Vps34), known...
Biochem J (2015) 466 (3): 431–442.
Published: 06 March 2015
... thrombosis The activities of Rho GTPase proteins are central to many of the processes that underpin the physiological and pathological roles of platelets [ 1 ]. Platelets are small, disc-shaped cells with a short lifespan that number in the hundreds of millions per millilitre of blood...
Ilaria Canobbio, Gianni F. Guidetti, Barbara Oliviero, Daria Manganaro, Dina Vara, Mauro Torti, Giordano Pula
Biochem J (2014) 462 (3): 513–523.
Published: 22 August 2014
... (AD) calcium platelet secretion thrombosis Abnormal metabolism of the APP (amyloid precursor protein) through the amyloidogenic pathway results in the accumulation of heterogeneous Aβ (amyloid β)-peptides (40–42 amino acids) in the central nervous system, causing the onset of AD...
Includes: Supplementary data
Biochem J (2011) 437 (3): 455–460.
Published: 13 July 2011
...@unsw.edu.au ). 20 4 2011 18 5 2011 20 5 2011 20 5 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 coagulation disulfide bond haemostasis redox potential thrombosis tissue factor TF (tissue factor) is the primary initiator of blood...
Maria Albertina Romaniuk, Maria Virginia Tribulatti, Valentina Cattaneo, Maria Jose Lapponi, Felisa Concepcion Molinas, Oscar Campetella, Mirta Schattner
Biochem J (2010) 432 (3): 535–547.
Published: 25 November 2010
... and cytometry showed that platelets not only contain Gal-8, but also expose Gal-8 after thrombin activation. These findings reveal Gal-8 as a potent platelet activator, supporting a role for this lectin in thrombosis and inflammation. 1 These authors contributed equally to this work. 2...
Biochem J (2006) 393 (2): 529–535.
Published: 23 December 2005
... simplex virus Herpesvirus thrombosis To confirm and quantify the relative amount of gC and TF on purified HSV1 strains, virus proteins were subjected to SDS/12% PAGE followed by electrotransfer on to PVDF membranes and evaluated by Western blot analysis [ 23 ]. Antigen was detected by incubation...
Anja P. EINHOLM, Katrine E. PEDERSEN, Troels WIND, Paulina KULIG, Michael T. OVERGAARD, Jan K. JENSEN, Julie S. BØDKER, Anni CHRISTENSEN, Peter CHARLTON, Peter A. ANDREASEN
Biochem J (2003) 373 (3): 723–732.
Published: 01 August 2003
... 27 3 2003 30 4 2003 30 4 2003 The Biochemical Society, London ©2003 2003 cancer protease serpin therapeutic target thrombosis Abbreviations used: bis-ANS, 4,4′-dianilino-1,1′-bisnaphthyl-5,5′-disulphonic acid, dipotassium salt; h, α-helix; HBS, Hepes-buffered...
Katrine E. PEDERSEN, Anja P. EINHOLM, Anni CHRISTENSEN, Lotte SCHACK, Troels WIND, John M. KENNEY, Peter A. ANDREASEN
Biochem J (2003) 372 (3): 747–755.
Published: 15 June 2003
... to pathological protein polymerization in general. 1 To whom correspondence should be addressed (e-mail email@example.com ). 2 12 2002 24 3 2003 26 3 2003 26 3 2003 The Biochemical Society, London ©2003 2003 cancer polymerization serpin thrombosis urokinase...
Márcia B. SILVA, Mirta SCHATTNER, Celso R.R. RAMOS, Inácio L.M. JUNQUEIRA-de-AZEVEDO, Míriam C. GUARNIERI, María A. LAZZARI, Claudio A.M. SAMPAIO, Roberto G. POZNER, Janaina S. VENTURA, Paulo L. HO, Ana M. CHUDZINSKI-TAVASSI
Biochem J (2003) 369 (1): 129–139.
Published: 01 January 2003
... metalloproteinases thrombosis Abbreviations used: berythractivase, B. erythr omelas prothrombin activase ; CONICET, Consejo Nacional de Investigaciones Científicas y Técnicas; E-64, trans -epoxysuccinyl- l -leucylamido-(4-guanidino)butane; FBS, fetal bovine serum; HUVECs, human umbilical-vein...
Marc A. LAFLEUR, Morley D. HOLLENBERG, Susan J. ATKINSON, Vera KNÄUPER, Gillian MURPHY, Dylan R. EDWARDS
Biochem J (2001) 357 (1): 107–115.
Published: 25 June 2001
... proteinase gelatinase-A proteinase inhibitors angiogenesis thrombosis Abbreviations used: BCA, bicinchronic acid; con A, concanavalin A; E64, trans -epoxysuccinyl- l -leucylamido-(4-guanidino)butane; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HUVEC, human umbilical-vein endothelial cell...