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Keywords: thrombosis
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Articles
Biochem J (2020) 477 (22): 4327–4342.
Published: 26 November 2020
... researchers to generate an impressive amount of data on the role of class I PI3Kα, β, δ and γ in platelet activation and in thrombosis. Furthermore, platelets do also express two class II PI3Ks (PI3KC2α and PI3KC2β), thought to generate PtdIns(3,4)P 2 and PtdIns3P, and the sole class III PI3K (Vps34), known...
Articles
Biochem J (2015) 466 (3): 431–442.
Published: 06 March 2015
... thrombosis The activities of Rho GTPase proteins are central to many of the processes that underpin the physiological and pathological roles of platelets [ 1 ]. Platelets are small, disc-shaped cells with a short lifespan that number in the hundreds of millions per millilitre of blood...
Articles
Biochem J (2014) 462 (3): 513–523.
Published: 22 August 2014
... (AD) calcium platelet secretion thrombosis Abnormal metabolism of the APP (amyloid precursor protein) through the amyloidogenic pathway results in the accumulation of heterogeneous Aβ (amyloid β)-peptides (40–42 amino acids) in the central nervous system, causing the onset of AD...
Includes: Supplementary data
Articles
Biochem J (2011) 437 (3): 455–460.
Published: 13 July 2011
...@unsw.edu.au ). 20 4 2011 18 5 2011 20 5 2011 20 5 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 coagulation disulfide bond haemostasis redox potential thrombosis tissue factor TF (tissue factor) is the primary initiator of blood...
Articles
Biochem J (2010) 432 (3): 535–547.
Published: 25 November 2010
... and cytometry showed that platelets not only contain Gal-8, but also expose Gal-8 after thrombin activation. These findings reveal Gal-8 as a potent platelet activator, supporting a role for this lectin in thrombosis and inflammation. 1 These authors contributed equally to this work. 2...
Articles
Biochem J (2006) 393 (2): 529–535.
Published: 23 December 2005
... simplex virus Herpesvirus thrombosis To confirm and quantify the relative amount of gC and TF on purified HSV1 strains, virus proteins were subjected to SDS/12% PAGE followed by electrotransfer on to PVDF membranes and evaluated by Western blot analysis [ 23 ]. Antigen was detected by incubation...
Articles
Biochem J (2003) 373 (3): 723–732.
Published: 01 August 2003
... 27 3 2003 30 4 2003 30 4 2003 The Biochemical Society, London ©2003 2003 cancer protease serpin therapeutic target thrombosis Abbreviations used: bis-ANS, 4,4′-dianilino-1,1′-bisnaphthyl-5,5′-disulphonic acid, dipotassium salt; h, α-helix; HBS, Hepes-buffered...
Articles
Biochem J (2003) 372 (3): 747–755.
Published: 15 June 2003
... to pathological protein polymerization in general. 1 To whom correspondence should be addressed (e-mail kep@mb.au.dk ). 2 12 2002 24 3 2003 26 3 2003 26 3 2003 The Biochemical Society, London ©2003 2003 cancer polymerization serpin thrombosis urokinase...
Articles
Biochem J (2003) 369 (1): 129–139.
Published: 01 January 2003
... metalloproteinases thrombosis Abbreviations used: berythractivase, B. erythr omelas prothrombin activase ; CONICET, Consejo Nacional de Investigaciones Científicas y Técnicas; E-64, trans -epoxysuccinyl- l -leucylamido-(4-guanidino)butane; FBS, fetal bovine serum; HUVECs, human umbilical-vein...
Articles
Biochem J (2001) 357 (1): 107–115.
Published: 25 June 2001
... proteinase gelatinase-A proteinase inhibitors angiogenesis thrombosis Abbreviations used: BCA, bicinchronic acid; con A, concanavalin A; E64, trans -epoxysuccinyl- l -leucylamido-(4-guanidino)butane; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HUVEC, human umbilical-vein endothelial cell...