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Keywords: thioredoxin peroxidase
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Biochem J (2007) 405 (1): 77–83.
Published: 13 June 2007
... with increased gene expression level of various antioxidant enzymes, including TRx (thioredoxin), TR (thioredoxin reductase) 1, TR2 and peroxiredoxin 1/TPx2 (thioredoxin peroxidase 2). Importantly, enforced TPx2 gene expression inhibited UV-C-induced A-SMase translocation. Finally, PKCζ inhibition led...
Biochem J (2006) 393 (2): 513–521.
Published: 23 December 2005
... of TPx I (thioredoxin peroxidase I), an enzyme that reduces the generation of intracellular ROS (reactive oxygen species). Additional data showed that ROS regulated both the deacylation and reacylation steps of C 6 -cer. At a functional level, C 6 -cer inhibited the DNA-binding function of the c-Myc/Max...