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Keywords: thapsigargin
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Biochem J (2018) 475 (1): 289–303.
Published: 11 January 2018
... to cyclopiazonic acid but different sensitivities to thapsigargin, two specific inhibitors of SERCA pumps. On the basis of transcriptomic data available in GeneDB, we hypothesize that SMA1 is a housekeeping Ca 2+ -ATPase, whereas SMA2 might be required in particular striated-like muscles like those present...
Includes: Supplementary data
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Biochem J (2007) 408 (2): 181–191.
Published: 14 November 2007
... a significant change in the secondary structure of fortilin. In order to evaluate the impact of the binding of fortilin to Ca 2+ in vivo , we measured intracellular Ca 2+ levels upon thapsigargin challenge and found that the lack of fortilin in the cell results in the exaggerated elevation of intracellular Ca 2...
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Biochem J (2003) 375 (3): 561–565.
Published: 01 November 2003
... for GlcCer-mediated sensitization of the RyaR. GlcSph-induced Ca 2+ mobilization was partially blocked by heparin, an inhibitor of the Ins(1,4,5) P 3 receptor, and also partially blocked by thapsigargin or ADP, inhibitors of SERCA (sarcoplasmic/endoplasmic reticulum Ca 2+ -ATPase), but completely blocked...
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Biochem J (2001) 357 (2): 363–371.
Published: 09 July 2001
... observed at both day 1 and 12. Thapsigargin (TG) prevented ATP- and caffeine-induced Ca 2+ transients at day 1. At day 12, where only 50% of the cells were sensitive to caffeine, TG did not prevent the caffeine-induced Ca 2+ transient, and prevented ATP-induced Ca 2+ transient in only half of the cells...
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